Author results

3JBN
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CRYO-ELECTRON MICROSCOPY RECONSTRUCTION OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME BOUND TO P-TRNA
Descriptor:18S ribosomal RNA, P-tRNA, 40S ribosomal protein uS3, ...
Authors:Sun, M., Li, W., Blomqvist, K., Das, S., Hashem, Y., Dvorin, J.D., Frank, J.
Deposit date:2015-09-16
Release date:2015-10-14
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Dynamical features of the Plasmodium falciparum ribosome during translation.
Nucleic Acids Res., 43, 2015
3JBO
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CRYO-ELECTRON MICROSCOPY RECONSTRUCTION OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME BOUND TO P/E-TRNA
Descriptor:18S ribosomal RNA, P/E-tRNA, 40S ribosomal protein uS12, ...
Authors:Sun, M., Li, W., Blomqvist, K., Das, S., Hashem, Y., Dvorin, J.D., Frank, J.
Deposit date:2015-09-16
Release date:2015-10-14
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Dynamical features of the Plasmodium falciparum ribosome during translation.
Nucleic Acids Res., 43, 2015
3JBP
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CRYO-ELECTRON MICROSCOPY RECONSTRUCTION OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME BOUND TO E-TRNA
Descriptor:18S ribosomal RNA, E-tRNA, 40S ribosomal protein uS3, ...
Authors:Sun, M., Li, W., Blomqvist, K., Das, S., Hashem, Y., Dvorin, J.D., Frank, J.
Deposit date:2015-09-16
Release date:2015-10-14
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Dynamical features of the Plasmodium falciparum ribosome during translation.
Nucleic Acids Res., 43, 2015
3PJP
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A TANDEM SH2 DOMAIN IN TRANSCRIPTION ELONGATION FACTOR SPT6 BINDS THE PHOSPHORYLATED RNA POLYMERASE II C-TERMINAL REPEAT DOMAIN(CTD)
Descriptor:Transcription elongation factor SPT6, ACETATE ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Sun, M., Lariviere, L., Dengl, S., Mayer, A., Cramer, P.
Deposit date:2010-11-10
Release date:2010-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A tandem SH2 domain in transcription elongation factor Spt6 binds the phosphorylated RNA polymerase II C-terminal repeat domain (CTD).
J.Biol.Chem., 285, 2010
4O2C
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AN NT-ACETYLATED PEPTIDE COMPLEXED WITH HLA-B*3901
Descriptor:HLA class I histocompatibility antigen, B-39 alpha chain, Beta-2-microglobulin, ...
Authors:Sun, M., Liu, J., Qi, J., Tefsen, B., Shi, Y., Yan, J., Gao, G.F.
Deposit date:2013-12-17
Release date:2014-07-23
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:N alpha-terminal acetylation for T cell recognition: molecular basis of MHC class I-restricted n alpha-acetylpeptide presentation
J.Immunol., 192, 2014
4O2E
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A PEPTIDE COMPLEXED WITH HLA-B*3901
Descriptor:HLA class I histocompatibility antigen, B-39 alpha chain, Beta-2-microglobulin, ...
Authors:Sun, M., Liu, J., Qi, J., Tefsen, B., Shi, Y., Yan, J., Gao, G.F.
Deposit date:2013-12-17
Release date:2014-07-23
Method:X-RAY DIFFRACTION (1.981 Å)
Cite:N alpha-terminal acetylation for T cell recognition: molecular basis of MHC class I-restricted n alpha-acetylpeptide presentation
J.Immunol., 192, 2014
4O2F
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A PEPTIDE COMPLEXED WITH HLA-B*3901
Descriptor:HLA class I histocompatibility antigen, B-39 alpha chain, Beta-2-microglobulin, ...
Authors:Sun, M., Liu, J., Qi, J., Tefsen, B., Shi, Y., Yan, J., Gao, G.F.
Deposit date:2013-12-17
Release date:2014-07-23
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:N alpha-terminal acetylation for T cell recognition: molecular basis of MHC class I-restricted n alpha-acetylpeptide presentation
J.Immunol., 192, 2014
3U1R
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STRUCTURE ANALYSIS OF A NEW PSYCHROPHILIC MARINE PROTEASE
Descriptor:Alkaline metalloprotease, ZINC ION, CALCIUM ION
Authors:Zhang, S.-C., Sun, M., Tang, L., Wang, Q.-H., Hao, J.-H., Han, Y., Hu, X.-J., Zhou, M., Lin, S.-X.
Deposit date:2011-09-30
Release date:2012-10-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure analysis of a new psychrophilic marine protease.
Plos One, 6, 2011
4D2H
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CRYSTAL STRUCTURE OF THE TETRAMERISATION DOMAIN OF HUMAN CTIP
Descriptor:RBBP8, SULFATE ION
Authors:Davies, O.R., Sun, M., Pellegrini, L.
Deposit date:2014-05-09
Release date:2015-01-14
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ctip Tetramer Assembly is Required for DNA-End Resection and Repair.
Nat.Struct.Mol.Biol., 22, 2015
5CE7
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STRUCTURE OF A NON-CANONICAL CID OF CTK3
Descriptor:CTD kinase subunit gamma, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Muehlbacher, W., Mayer, A., Sun, M., Remmert, M., Cheung, A.C., Niesser, J., Soeding, J., Cramer, P.
Deposit date:2015-07-06
Release date:2015-08-05
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a noncanonical CTD-interacting domain fold.
Proteins, 83, 2015
5T5H
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STRUCTURE AND ASSEMBLY MODEL FOR THE TRYPANOSOMA CRUZI 60S RIBOSOMAL SUBUNIT
Descriptor:RNA LARGE SUBUNIT ALPHA, RNA LARGE SUBUNIT BETA, 5.8S rRNA, ...
Authors:Liu, Z., Gutierrez-Vargas, C., Wei, J., Grassucci, R.A., Ramesh, M., Espina, N., Sun, M., Tutuncuoglu, B., Madison-Antenucci, S., Woolford Jr., J.L., Tong, L., Frank, J.
Deposit date:2016-08-31
Release date:2016-10-12
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit.
Proc.Natl.Acad.Sci.USA, 113, 2016
6ORL
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RF1 PRE-ACCOMMODATED 70S COMPLEX AT 24 MS
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Fu, Z., Indrisiunaite, G., Kaledhonkar, S., Shah, B., Sun, M., Chen, B., Grassucci, R.A., Ehrenberg, M., Frank, J.
Deposit date:2019-04-30
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OSK
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RF1 ACCOMMODATED 70S COMPLEX AT 60 MS
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Fu, Z., Indrisiunaite, G., Kaledhonkar, S., Shah, B., Sun, M., Chen, B., Grassucci, R.A., Ehrenberg, M., Frank, J.
Deposit date:2019-05-01
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OSQ
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RF1 ACCOMMODATED STATE BOUND RELEASE COMPLEX 70S AT LONG INCUBATION TIME POINT
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Fu, Z., Indrisiunaite, G., Kaledhonkar, S., Shah, B., Sun, M., Chen, B., Grassucci, R.A., Ehrenberg, M., Frank, J.
Deposit date:2019-05-02
Release date:2019-06-26
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OST
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RF2 PRE-ACCOMMODATED STATE BOUND RELEASE COMPLEX 70S AT 24MS
Descriptor:23S Ribosomal RNA, 16S Ribosomal RNA, 5S Ribosomal RNA, ...
Authors:Fu, Z., Indrisiunaite, G., Kaledhonkar, S., Shah, B., Sun, M., Chen, B., Grassucci, R.A., Ehrenberg, M., Frank, J.
Deposit date:2019-05-02
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OT3
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RF2 ACCOMMODATED STATE BOUND RELEASE COMPLEX 70S AT 24 MS
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Fu, Z., Indrisiunaite, G., Kaledhonkar, S., Shah, B., Sun, M., Chen, B., Grassucci, R.A., Ehrenberg, M., Frank, J.
Deposit date:2019-05-02
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OUO
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RF2 ACCOMMODATED STATE BOUND 70S COMPLEX AT LONG INCUBATION TIME
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Fu, Z., Indrisiunaite, G., Kaledhonkar, S., Shah, B., Sun, M., Chen, B., Grassucci, R.A., Ehrenberg, M., Frank, J.
Deposit date:2019-05-05
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
1YT9
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HIV PROTEASE WITH OXIMINOARYLSULFONAMIDE BOUND
Descriptor:Pol polyprotein, (S)-N-((2S,3R)-3-HYDROXY-4-(4-((E)-(HYDROXYIMINO)METHYL)-N-ISOBUTYLPHENYLSULFONAMIDO)-1-PHENYLBUTAN-2-YL)-3-METHYL-2-(3-((2-METHYLTHIAZOL-4-YL)METHYL)-2-OXOIMIDAZOLIDIN-1-YL)BUTANAMIDE
Authors:Yeung, C.M., Klein, L.L., Flentge, C.A., Randolph, J.T., Zhao, C., Sun, M., Dekhtyar, T., Stoll, V.S., Kempf, D.J.
Deposit date:2005-02-10
Release date:2005-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Oximinoarylsulfonamides as potent HIV protease inhibitors.
Bioorg.Med.Chem.Lett., 15, 2005
2A4F
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SYNTHESIS AND ACTIVITY OF N-AXYL AZACYCLIC UREA HIV-1 PROTEASE INHIBITORS WITH HIGH POTENCY AGAINST MULTIPLE DRUG RESISTANT VIRAL STRAINS.
Descriptor:Pol polyprotein, (5R,6R)-5-BENZYL-6-HYDROXY-2,4-BIS(4-HYDROXY-3-METHOXYBENZYL)-1-[3-(4-HYDROXYPHENYL)PROPANOYL]-1,2,4-TRIAZEPAN-3-ONE
Authors:Zhao, C., Sham, H., Sun, M., Lin, S., Stoll, V., Stewart, K.D., Mo, H., Vasavanonda, S., Saldivar, A., McDonald, E.
Deposit date:2005-06-28
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Synthesis and activity of N-acyl azacyclic urea HIV-1 protease inhibitors with high potency against multiple drug resistant viral strains
Bioorg.Med.Chem.Lett., 15, 2005
2EX0
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CRYSTAL STRUCTURE OF MULTIFUNCTIONAL SIALYLTRANSFERASE FROM PASTEURELLA MULTOCIDA
Descriptor:a2,3-sialyltransferase, a2,6-sialyltransferase
Authors:Ni, L., Sun, M., Chen, X., Fisher, A.J.
Deposit date:2005-11-07
Release date:2006-02-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Cytidine 5'-Monophosphate (CMP)-Induced Structural Changes in a Multifunctional Sialyltransferase from Pasteurella multocida
Biochemistry, 45, 2006
2EX1
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CRYSTAL STRUCTURE OF MUTIFUNCTIONAL SIALYLTRANSFERASE FROM PASTEURELLA MULTOCIDA WITH CMP BOUND
Descriptor:a2,3-sialyltransferase, a2,a6-sialyltransferase, CYTIDINE-5'-MONOPHOSPHATE
Authors:Ni, L., Sun, M., Chen, X., Fisher, A.J.
Deposit date:2005-11-07
Release date:2006-02-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cytidine 5'-Monophosphate (CMP)-Induced Structural Changes in a Multifunctional Sialyltransferase from Pasteurella multocida
Biochemistry, 45, 2006
2VUJ
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ENVIRONMENTALLY ISOLATED GH11 XYLANASE
Descriptor:GH11 XYLANASE, GLYCEROL
Authors:Dumon, C., Varvak, A., Wall, M.A., Flint, J.E., Lewis, R.J., Lakey, J.H., Luginbuhl, P., Healey, S., Todaro, T., DeSantis, G., Sun, M., Parra-Gessert, L., Tan, X., Weiner, D.P., Gilbert, H.J.
Deposit date:2008-05-26
Release date:2008-06-17
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Engineering Hyperthermostability Into a Gh11 Xylanase is Mediated by Subtle Changes to Protein Structure.
J.Biol.Chem., 283, 2008
2VUL
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THERMOSTABLE MUTANT OF ENVIRONMENTALLY ISOLATED GH11 XYLANASE
Descriptor:GH11 XYLANASE, SULFATE ION, DODECAETHYLENE GLYCOL
Authors:Dumon, C., Varvak, A., Wall, M.A., Flint, J.E., Lewis, R.J., Lakey, J.H., Luginbuhl, P., Healey, S., Todaro, T., Desantis, G., Sun, M., Parra-Gessert, L., Tan, X., Weiner, D.P., Gilbert, H.J.
Deposit date:2008-05-27
Release date:2008-06-17
Last modified:2014-06-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Engineering Hyperthermostability Into a Gh11 Xylanase is Mediated by Subtle Changes to Protein Structure.
J.Biol.Chem., 283, 2008
3GXW
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STRUCTURE OF THE SH2 DOMAIN OF THE CANDIDA GLABRATA TRANSCRIPTION ELONGATION FACTOR SPT6, CRYSTAL FORM A
Descriptor:Transcription elongation factor SPT6, SUCCINIC ACID, SODIUM ION
Authors:Dengl, S., Mayer, A., Sun, M., Cramer, P.
Deposit date:2009-04-03
Release date:2009-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and in vivo requirement of the yeast Spt6 SH2 domain
J.Mol.Biol., 389, 2009
3GXX
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STRUCTURE OF THE SH2 DOMAIN OF THE CANDIDA GLABRATA TRANSCRIPTION ELONGATION FACTOR SPT6, CRYSTAL FORM B
Descriptor:Transcription elongation factor SPT6
Authors:Dengl, S., Mayer, A., Sun, M., Cramer, P.
Deposit date:2009-04-03
Release date:2009-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and in vivo requirement of the yeast Spt6 SH2 domain
J.Mol.Biol., 389, 2009
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