Author results

2DK9
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SOLUTION STRUCTURE OF CALPONIN HOMOLOGY DOMAIN OF HUMAN MICAL-1
分子名称:NEDD9-interacting protein with calponin homology and LIM domains
著者Sun, H., Dai, H., Zhang, J., Xiong, S., Wu, J., Shi, Y.
登録日2006-04-07
公開日2006-09-19
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of calponin homology domain of Human MICAL-1
J.Biomol.Nmr, 36, 2006
2I7K
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SOLUTION STRUCTURE OF THE BROMODOMAIN OF HUMAN BRD7 PROTEIN
分子名称:Bromodomain-containing protein 7
著者Sun, H., Liu, J., Zhang, J., Huang, H., Wu, J., Shi, Y.
登録日2006-08-31
公開日2007-07-10
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of BRD7 bromodomain and its interaction with acetylated peptides from histone H3 and H4
Biochem.Biophys.Res.Commun., 358, 2007
5WTD
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STRUCTURE OF HUMAN SERUM TRANSFERRIN BOUND RUTHENIUM AT N-LOBE
分子名称:Serotransferrin, FE (III) ION, MALONATE ION, ...
著者Sun, H., Wang, M., Lai, T.P., Zhang, H., Hao, Q.
登録日2016-12-11
公開日2017-12-20
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Ruthenium bound to the N-lobe of human serum transferrin
To Be Published
5X5P
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HUMAN SERUM TRANSFERRIN BOUND TO RUTHENIUM NTA
分子名称:Serotransferrin, MALONATE ION, FE (III) ION, ...
著者Sun, H., Wang, M.
登録日2017-02-17
公開日2018-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The additional metal-binding site on human serum transferrin surface
To Be Published
2XFL
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INDUCED-FIT AND ALLOSTERIC EFFECTS UPON POLYENE BINDING REVEALED BY CRYSTAL STRUCTURES OF THE DYNEMICIN THIOESTERASE
分子名称:DYNE7
著者Liew, C.W., Sharff, A., Kotaka, M., Kong, R., Sun, H., Bricogne, G., Liang, Z., Lescar, J.
登録日2010-05-26
公開日2010-10-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Induced-Fit Upon Ligand Binding Revealed by Crystal Structures of the Hot-Dog Fold Thioesterase in Dynemicin Biosynthesis.
J.Mol.Biol., 404, 2010
6BNS
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STRUCTURE OF HUMAN PREGNANE X RECEPTOR LIGAND BINDING DOMAIN BOUND TETHERED WITH SRC CO-ACTIVATOR PEPTIDE AND COMPOUND 25A AKA BICYCLIC HEXAFLUOROISOPROPYL 2 ALCOHOL SULFONAMIDES
分子名称:Nuclear receptor subfamily 1 group I member 2,Nuclear receptor coactivator 1 Chimera, 2-[(2S)-4-[(4-fluorophenyl)sulfonyl]-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-3,4-dihydro-2H-1,4-benzothiazin-2-yl]-N-(2-hydroxy-2-methylpropyl)acetamide
著者DHAR, T.G., GONG, H., WEINSTEIN, D.S., LU, Z., DUAN, J.J.W., STACHURA, S., HAQUE, L., KARMAKAR, A., HEMAGIRI, H., RAUT, D.K., GUPTA, A.K., KHAN, J.A., SACK, J.S., CAMAC, D.M., PUDZIANOWSKI, A.A., WU, D.R., YARDE, M., SHEN, D.R., BOROWSKI, V., XIE, J.H., SUN, H., ARIENZO, C.D., DABROS, M., GALELLA, M.A., WANG, F., WEIGELT, C.A., ZHAO, Q., FOSTER, W., SOMERVILLE, J.E., SALTER-CID, L.M., BARRISH, J.C., CARTER, P.H.
登録日2017-11-17
公開日2017-12-20
最終更新日2018-01-03
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (ROR gamma /RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity.
Bioorg. Med. Chem. Lett., 28, 2018
2KR7
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SOLUTION STRUCTURE OF HELICOBACTER PYLORI SLYD
分子名称:FKBP-type peptidyl-prolyl cis-trans isomerase slyD
著者Cheng, T., Li, H., Xia, W., Sze, K., Sun, H.
登録日2009-12-07
公開日2010-12-15
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献solution structure of Helicobacter pylori SlyD
To be Published
3QYT
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DIFERRIC BOUND HUMAN SERUM TRANSFERRIN
分子名称:Serotransferrin, FE (III) ION, CARBONATE ION, ...
著者Yang, N., Zhang, H., Wang, M., Hao, Q., Sun, H.
登録日2011-03-03
公開日2012-03-14
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe
Sci Rep, 2, 2012
4DZO
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STRUCTURE OF HUMAN MAD1 C-TERMINAL DOMAIN REVEALS ITS INVOLVEMENT IN KINETOCHORE TARGETING
分子名称:Mitotic spindle assembly checkpoint protein MAD1
著者Luo, X., Sun, H., Tomchick, D.R.
登録日2012-03-01
公開日2012-04-11
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structure of human Mad1 C-terminal domain reveals its involvement in kinetochore targeting.
Proc.Natl.Acad.Sci.USA, 109, 2012
4H0W
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BISMUTH BOUND HUMAN SERUM TRANSFERRIN
分子名称:Serotransferrin, FE (III) ION, CARBONATE ION, ...
著者Yang, N., Zhang, H., Wang, M., Hao, Q., Sun, H.
登録日2012-09-10
公開日2012-12-26
最終更新日2013-01-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe.
Sci Rep, 2, 2012
4X1B
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HUMAN SERUM TRANSFERRIN WITH FERRIC ION BOUND AT THE C-LOBE ONLY
分子名称:Serotransferrin, FE (III) ION, MALONATE ION, ...
著者Wang, M., Zhang, H., Sun, H.
登録日2014-11-24
公開日2015-04-08
最終更新日2015-05-06
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献"Anion clamp" allows flexible protein to impose coordination geometry on metal ions
Chem.Commun.(Camb.), 51, 2015
4X1D
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YTTERBIUM-BOUND HUMAN SERUM TRANSFERRIN
分子名称:Serotransferrin, YTTERBIUM (III) ION, MALONATE ION, ...
著者Wang, M., Zhang, H., Sun, H.
登録日2014-11-24
公開日2015-04-08
最終更新日2015-05-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献"Anion clamp" allows flexible protein to impose coordination geometry on metal ions
Chem.Commun.(Camb.), 51, 2015
5XP6
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NATIVE STRUCTURE OF NDM-1 CRYSTALLIZED AT PH5.5
分子名称:Metallo-beta-lactamase type 2, ZINC ION, HYDROXIDE ION, ...
著者Zhang, H., Ma, G., Lai, J., Sun, H.
登録日2017-06-01
公開日2018-03-07
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Bismuth antimicrobial drugs serve as broad-spectrum metallo-beta-lactamase inhibitors
Nat Commun, 9, 2018
5XP9
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CRYSTAL STRUCTURE OF BISMUTH BOUND NDM-1
分子名称:Metallo-beta-lactamase type 2, Bismuth(III) ION, GLYCEROL
著者Zhang, H., Ma, G., Lai, T.P., Sun, H.
登録日2017-06-01
公開日2018-03-07
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Bismuth antimicrobial drugs serve as broad-spectrum metallo-beta-lactamase inhibitors
Nat Commun, 9, 2018
5Y6K
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HUMAN SERUM TRNASFERRIN BOUND TO A FLUORESCENT PROBE
分子名称:Serotransferrin, MALONATE ION, FE (III) ION, ...
著者Jiang, N., Cheng, T., Wang, M., Chan, G.C.F., Jin, L., Li, H., Sun, H.
登録日2017-08-12
公開日2018-01-24
最終更新日2018-02-07
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Tracking iron-associated proteomes in pathogens by a fluorescence approach.
Metallomics, 10, 2018
5Z3W
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MALATE DEHYDROGENASE BINDS SILVER AT C113
分子名称:Malate dehydrogenase, SILVER ION
著者Wang, H., Wang, M., Sun, H.
登録日2018-01-09
公開日2019-01-16
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structure of silver-bound malate dehydrogenase
To Be Published
6IO4
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SILVER-BOUND GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE A
分子名称:Glyceraldehyde-3-phosphate dehydrogenase A, SILVER ION
著者Wang, H., Sun, H., Wang, M.
登録日2018-10-29
公開日2019-07-03
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis of E. coli
Chem Sci, 2019
6IO6
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SILVER-BOUND GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE A AT NON-CATALYTIC SITE
分子名称:Glyceraldehyde-3-phosphate dehydrogenase A, SILVER ION
著者Wang, H., Sun, H., Wang, M.
登録日2018-10-29
公開日2019-07-03
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis of E. coli
Chem Sci, 2019
6IOJ
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GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE A (APO-FORM)
分子名称:Glyceraldehyde-3-phosphate dehydrogenase A
著者Wang, H., Sun, H., Wang, M.
登録日2018-10-30
公開日2019-07-03
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis of E. coli
Chem Sci, 2019
5X5S
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LIGAND INDUCED STRUCTURE OF AMYP-SBD
分子名称:Amylase
著者Li, X., Yu, J., Sun, H., Zhang, X.
登録日2017-02-17
公開日2017-04-05
実験手法SOLUTION NMR
主引用文献Ligand binding induced folding of a novel CBM69 starch binding domain
To Be Published
1QHI
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HERPES SIMPLEX VIRUS TYPE-I THYMIDINE KINASE COMPLEXED WITH A NOVEL NON-SUBSTRATE INHIBITOR, 9-(4-HYDROXYBUTYL)-N2-PHENYLGUANINE
分子名称:PROTEIN (THYMIDINE KINASE), SULFATE ION, 9-(4-HYDROXYBUTYL)-N2-PHENYLGUANINE
著者Bennett, M.S., Wien, F., Champness, J.N., Batuwangala, T., Rutherford, T., Summers, W.C., Sun, H., Wright, G., Sanderson, M.R.
登録日1999-05-12
公開日1999-07-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure to 1.9 A resolution of a complex with herpes simplex virus type-1 thymidine kinase of a novel, non-substrate inhibitor: X-ray crystallographic comparison with binding of aciclovir.
FEBS Lett., 443, 1999
2KI5
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HERPES SIMPLEX TYPE-1 THYMIDINE KINASE IN COMPLEX WITH THE DRUG ACICLOVIR AT 1.9A RESOLUTION
分子名称:PROTEIN (THYMIDINE KINASE), SULFATE ION, 9-HYROXYETHOXYMETHYLGUANINE
著者Bennett, M.S., Wien, F., Champness, J.N., Batuwangala, T., Rutherford, T., Summers, W.C., Sun, H., Wright, G., Sanderson, M.R.
登録日1999-02-12
公開日1999-03-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure to 1.9 A resolution of a complex with herpes simplex virus type-1 thymidine kinase of a novel, non-substrate inhibitor: X-ray crystallographic comparison with binding of aciclovir.
FEBS Lett., 443, 1999
2W3X
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CRYSTAL STRUCTURE OF A BIFUNCTIONAL HOTDOG FOLD THIOESTERASE IN ENEDIYNE BIOSYNTHESIS, CALE7
分子名称:CALE7, PHOSPHATE ION, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), ...
著者Kotaka, M., Kong, R., Qureshi, I., Ho, Q.S., Sun, H., Liew, C.W., Goh, L.P., Cheung, P., Mu, Y., Lescar, J., Liang, Z.X.
登録日2008-11-17
公開日2009-04-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure and Catalytic Mechanism of the Thioesterase Cale7 in Enediyne Biosynthesis.
J.Biol.Chem., 284, 2009
3S49
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RNA CRYSTAL STRUCTURE WITH 2-SE-URIDINE MODIFICATION
分子名称:RNA (5'-R(*GP*UP*AP*UP*AP*(RUS)P*AP*C)-3'), POTASSIUM ION
著者Sheng, J., Gan, J., Sun, H., Hassan, A.E.H., Jiang, S., Huang, Z.
登録日2011-05-19
公開日2011-06-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Higher Specificity of RNA Base Pairing with 2-Selenouridine
To be Published
4JAB
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U/G WOBBLE BASE PAIR IN A RNA DUPLEX
分子名称:RNA (5'-R(*GP*UP*GP*UP*AP*UP*AP*C)-3'), STRONTIUM ION
著者Jiang, S., Sun, H., Gan, J., Huang, Z.
登録日2013-02-18
公開日2014-01-29
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献2-Se Uridine enhanced U/G Wobble Base Pair Discrimination
To be Published