Author results

2I7K
  • Download 2i7k
  • View 2i7k
Molmil generated image of 2i7k
SOLUTION STRUCTURE OF THE BROMODOMAIN OF HUMAN BRD7 PROTEIN
分子名称:Bromodomain-containing protein 7
著者Sun, H., Liu, J., Zhang, J., Huang, H., Wu, J., Shi, Y.
登録日2006-08-31
公開日2007-07-10
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of BRD7 bromodomain and its interaction with acetylated peptides from histone H3 and H4
Biochem.Biophys.Res.Commun., 358, 2007
2DK9
  • Download 2dk9
  • View 2dk9
Molmil generated image of 2dk9
SOLUTION STRUCTURE OF CALPONIN HOMOLOGY DOMAIN OF HUMAN MICAL-1
分子名称:NEDD9-interacting protein with calponin homology and LIM domains
著者Sun, H., Dai, H., Zhang, J., Xiong, S., Wu, J., Shi, Y.
登録日2006-04-07
公開日2006-09-19
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of calponin homology domain of Human MICAL-1
J.Biomol.Nmr, 36, 2006
5WTD
  • Download 5wtd
  • View 5wtd
Molmil generated image of 5wtd
STRUCTURE OF HUMAN SERUM TRANSFERRIN BOUND RUTHENIUM AT N-LOBE
分子名称:Serotransferrin, FE (III) ION, MALONATE ION, ...
著者Sun, H., Wang, M., Lai, T.P., Zhang, H., Hao, Q.
登録日2016-12-11
公開日2017-12-20
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Ruthenium bound to the N-lobe of human serum transferrin
To Be Published
6M1V
  • Download 6m1v
  • View 6m1v
Molmil generated image of 6m1v
CRYSTAL STRUCTURE OF POST FUSION CORE OF 2019-NCOV S2 SUBUNIT
分子名称:spike protein
著者Sun, H., Song, H., Wang, Q.
登録日2020-02-26
公開日2020-06-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of post fusion core of 2019-nCoV S2 subunit
To Be Published
5X5P
  • Download 5x5p
  • View 5x5p
Molmil generated image of 5x5p
HUMAN SERUM TRANSFERRIN BOUND TO RUTHENIUM NTA
分子名称:Serotransferrin, MALONATE ION, FE (III) ION, ...
著者Sun, H., Wang, M.
登録日2017-02-17
公開日2018-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The additional metal-binding site on human serum transferrin surface
To Be Published
6KV9
  • Download 6kv9
  • View 6kv9
Molmil generated image of 6kv9
MOEE5 IN COMPLEX WITH UDP-GLUCURONIC ACID AND NAD
分子名称:MoeE5, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID
著者Ko, T.-P., Liu, W., Sun, H., Liu, W., Chen, C.-C., Guo, R.-T.
登録日2019-09-03
公開日2019-11-13
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Structure of an antibiotic-synthesizing UDP-glucuronate 4-epimerase MoeE5 in complex with substrate.
Biochem.Biophys.Res.Commun., 521, 2020
6KVC
  • Download 6kvc
  • View 6kvc
Molmil generated image of 6kvc
MOEE5 IN COMPLEX WITH UDP-GLUCOSE AND NAD
分子名称:MoeE5, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE-GLUCOSE
著者Ko, T.-P., Liu, W., Sun, H., Liu, W., Chen, C.-C., Guo, R.-T.
登録日2019-09-04
公開日2019-11-13
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structure of an antibiotic-synthesizing UDP-glucuronate 4-epimerase MoeE5 in complex with substrate.
Biochem.Biophys.Res.Commun., 521, 2020
2XFL
  • Download 2xfl
  • View 2xfl
Molmil generated image of 2xfl
INDUCED-FIT AND ALLOSTERIC EFFECTS UPON POLYENE BINDING REVEALED BY CRYSTAL STRUCTURES OF THE DYNEMICIN THIOESTERASE
分子名称:DYNE7
著者Liew, C.W., Sharff, A., Kotaka, M., Kong, R., Sun, H., Bricogne, G., Liang, Z., Lescar, J.
登録日2010-05-26
公開日2010-10-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Induced-Fit Upon Ligand Binding Revealed by Crystal Structures of the Hot-Dog Fold Thioesterase in Dynemicin Biosynthesis.
J.Mol.Biol., 404, 2010
4DZO
  • Download 4dzo
  • View 4dzo
Molmil generated image of 4dzo
STRUCTURE OF HUMAN MAD1 C-TERMINAL DOMAIN REVEALS ITS INVOLVEMENT IN KINETOCHORE TARGETING
分子名称:Mitotic spindle assembly checkpoint protein MAD1
著者Luo, X., Sun, H., Tomchick, D.R.
登録日2012-03-01
公開日2012-04-11
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structure of human Mad1 C-terminal domain reveals its involvement in kinetochore targeting.
Proc.Natl.Acad.Sci.USA, 109, 2012
5XP6
  • Download 5xp6
  • View 5xp6
Molmil generated image of 5xp6
NATIVE STRUCTURE OF NDM-1 CRYSTALLIZED AT PH5.5
分子名称:Metallo-beta-lactamase type 2, ZINC ION, HYDROXIDE ION, ...
著者Zhang, H., Ma, G., Lai, J., Sun, H.
登録日2017-06-01
公開日2018-03-07
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Bismuth antimicrobial drugs serve as broad-spectrum metallo-beta-lactamase inhibitors
Nat Commun, 9, 2018
5XP9
  • Download 5xp9
  • View 5xp9
Molmil generated image of 5xp9
CRYSTAL STRUCTURE OF BISMUTH BOUND NDM-1
分子名称:Metallo-beta-lactamase type 2, Bismuth(III) ION, GLYCEROL
著者Zhang, H., Ma, G., Lai, T.P., Sun, H.
登録日2017-06-01
公開日2018-03-07
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Bismuth antimicrobial drugs serve as broad-spectrum metallo-beta-lactamase inhibitors
Nat Commun, 9, 2018
6BNS
  • Download 6bns
  • View 6bns
Molmil generated image of 6bns
STRUCTURE OF HUMAN PREGNANE X RECEPTOR LIGAND BINDING DOMAIN BOUND TETHERED WITH SRC CO-ACTIVATOR PEPTIDE AND COMPOUND 25A AKA BICYCLIC HEXAFLUOROISOPROPYL 2 ALCOHOL SULFONAMIDES
分子名称:Nuclear receptor subfamily 1 group I member 2,Nuclear receptor coactivator 1 Chimera, 2-[(2S)-4-[(4-fluorophenyl)sulfonyl]-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-3,4-dihydro-2H-1,4-benzothiazin-2-yl]-N-(2-hydroxy-2-methylpropyl)acetamide
著者DHAR, T.G., GONG, H., WEINSTEIN, D.S., LU, Z., DUAN, J.J.W., STACHURA, S., HAQUE, L., KARMAKAR, A., HEMAGIRI, H., RAUT, D.K., GUPTA, A.K., KHAN, J.A., SACK, J.S., CAMAC, D.M., PUDZIANOWSKI, A.A., WU, D.R., YARDE, M., SHEN, D.R., BOROWSKI, V., XIE, J.H., SUN, H., ARIENZO, C.D., DABROS, M., GALELLA, M.A., WANG, F., WEIGELT, C.A., ZHAO, Q., FOSTER, W., SOMERVILLE, J.E., SALTER-CID, L.M., BARRISH, J.C., CARTER, P.H.
登録日2017-11-17
公開日2017-12-20
最終更新日2018-01-03
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (ROR gamma /RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity.
Bioorg. Med. Chem. Lett., 28, 2018
6IO4
  • Download 6io4
  • View 6io4
Molmil generated image of 6io4
SILVER-BOUND GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE A
分子名称:Glyceraldehyde-3-phosphate dehydrogenase A, SILVER ION
著者Wang, H., Sun, H., Wang, M.
登録日2018-10-29
公開日2019-07-03
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis ofE. coli.
Chem Sci, 10, 2019
6IO6
  • Download 6io6
  • View 6io6
Molmil generated image of 6io6
SILVER-BOUND GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE A AT NON-CATALYTIC SITE
分子名称:Glyceraldehyde-3-phosphate dehydrogenase A, SILVER ION
著者Wang, H., Sun, H., Wang, M.
登録日2018-10-29
公開日2019-07-03
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis ofE. coli.
Chem Sci, 10, 2019
6IOJ
  • Download 6ioj
  • View 6ioj
Molmil generated image of 6ioj
GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE A (APO-FORM)
分子名称:Glyceraldehyde-3-phosphate dehydrogenase A
著者Wang, H., Sun, H., Wang, M.
登録日2018-10-30
公開日2019-07-03
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis ofE. coli.
Chem Sci, 10, 2019
2KR7
  • Download 2kr7
  • View 2kr7
Molmil generated image of 2kr7
SOLUTION STRUCTURE OF HELICOBACTER PYLORI SLYD
分子名称:FKBP-type peptidyl-prolyl cis-trans isomerase slyD
著者Cheng, T., Li, H., Xia, W., Sze, K., Sun, H.
登録日2009-12-07
公開日2010-12-15
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献solution structure of Helicobacter pylori SlyD
To be Published
3QYT
  • Download 3qyt
  • View 3qyt
Molmil generated image of 3qyt
DIFERRIC BOUND HUMAN SERUM TRANSFERRIN
分子名称:Serotransferrin, FE (III) ION, CARBONATE ION, ...
著者Yang, N., Zhang, H., Wang, M., Hao, Q., Sun, H.
登録日2011-03-03
公開日2012-03-14
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe
Sci Rep, 2, 2012
4H0W
  • Download 4h0w
  • View 4h0w
Molmil generated image of 4h0w
BISMUTH BOUND HUMAN SERUM TRANSFERRIN
分子名称:Serotransferrin, FE (III) ION, CARBONATE ION, ...
著者Yang, N., Zhang, H., Wang, M., Hao, Q., Sun, H.
登録日2012-09-10
公開日2012-12-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe.
Sci Rep, 2, 2012
4X1B
  • Download 4x1b
  • View 4x1b
Molmil generated image of 4x1b
HUMAN SERUM TRANSFERRIN WITH FERRIC ION BOUND AT THE C-LOBE ONLY
分子名称:Serotransferrin, FE (III) ION, MALONATE ION, ...
著者Wang, M., Zhang, H., Sun, H.
登録日2014-11-24
公開日2015-04-08
最終更新日2015-05-06
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献"Anion clamp" allows flexible protein to impose coordination geometry on metal ions
Chem.Commun.(Camb.), 51, 2015
4X1D
  • Download 4x1d
  • View 4x1d
Molmil generated image of 4x1d
YTTERBIUM-BOUND HUMAN SERUM TRANSFERRIN
分子名称:Serotransferrin, YTTERBIUM (III) ION, MALONATE ION, ...
著者Wang, M., Zhang, H., Sun, H.
登録日2014-11-24
公開日2015-04-08
最終更新日2015-05-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献"Anion clamp" allows flexible protein to impose coordination geometry on metal ions
Chem.Commun.(Camb.), 51, 2015
5Y6K
  • Download 5y6k
  • View 5y6k
Molmil generated image of 5y6k
HUMAN SERUM TRNASFERRIN BOUND TO A FLUORESCENT PROBE
分子名称:Serotransferrin, MALONATE ION, FE (III) ION, ...
著者Jiang, N., Cheng, T., Wang, M., Chan, G.C.F., Jin, L., Li, H., Sun, H.
登録日2017-08-12
公開日2018-01-24
最終更新日2018-02-07
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Tracking iron-associated proteomes in pathogens by a fluorescence approach.
Metallomics, 10, 2018
5Z3W
  • Download 5z3w
  • View 5z3w
Molmil generated image of 5z3w
MALATE DEHYDROGENASE BINDS SILVER AT C113
分子名称:Malate dehydrogenase, SILVER ION
著者Wang, H., Wang, M., Sun, H.
登録日2018-01-09
公開日2019-01-16
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structure of silver-bound malate dehydrogenase
To Be Published
6JAS
  • Download 6jas
  • View 6jas
Molmil generated image of 6jas
HUMAN SERUM TRANSFERRIN WITH IRON CITRATE BOUND
分子名称:Serotransferrin, FE (III) ION, MALONATE ION, ...
著者Wang, M., Wang, H., Sun, H.
登録日2019-01-25
公開日2020-01-29
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Binding of ruthenium and osmium at non-iron sites of transferrin explains their iron-independent cellular uptake
To Be Published
6KA0
  • Download 6ka0
  • View 6ka0
Molmil generated image of 6ka0
SILVER-BOUND E.COLI MALATE DEHYDROGENASE
分子名称:Malate dehydrogenase, SILVER ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
著者Wang, H., Wang, M., Sun, H.
登録日2019-06-19
公開日2020-06-17
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献MDH is a major silver target in E. coli
To Be Published
6KA1
  • Download 6ka1
  • View 6ka1
Molmil generated image of 6ka1
E.COLI MALATE DEHYDROGENASE
分子名称:Malate dehydrogenase
著者Wang, H., Wang, M., Sun, H.
登録日2019-06-19
公開日2020-06-17
実験手法X-RAY DIFFRACTION (1.543 Å)
主引用文献MDH is a major silver target in E. coli
To Be Published
167132
件を2020-07-29に公開中