Author results

3KVG
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HSP70 (CGD2_20) FROM CRYPTOSPORIDIUM PARVUM IN COMPLEX WITH AMPPNP
Descriptor:Heat shock 70 (HSP70) protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 1,2-ETHANEDIOL, ...
Authors:Wernimont, A.K., Hutchinson, A., Sullivan, H., Lew, J., Bochkarev, A., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Hui, R., Pizarro, J.C., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2009-11-30
Release date:2010-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of the N-terminal domain of Hsp70 (cgd2_20) from Cryptosporidium parvum in complex with AMPPNP
To be Published
3L19
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CRYSTAL STRUCTURE OF CALCIUM BINDING DOMAIN OF CPCDPK3, CGD5_820
Descriptor:Calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands, CALCIUM ION, GLYCEROL, ...
Authors:Qiu, W., Hutchinson, A., Wernimont, A., Walker, J.R., Sullivan, H., Lin, Y.-H., Mackenzie, F., Kozieradzki, I., Cossar, D., Schapira, M., Senisterra, G., Vedadi, M., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Bochkarev, A., Hui, R., Amani, M., Structural Genomics Consortium (SGC)
Deposit date:2009-12-11
Release date:2009-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Crystal structure of calcium binding domain of CpCDPK3, cgd5_820
To be Published
3L4I
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HSP70 (CGD2_20) FROM CRYPTOSPORIDIUM PARVUM IN COMPLEX WITH ADP AND INORGANIC PHOSPHATE
Descriptor:Heat shock 70 (HSP70) protein, ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ...
Authors:Pizarro, J.C., Wernimont, A.K., Hutchinson, A., Sullivan, H., Lew, J., Bochkarev, A., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Hui, R., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2009-12-20
Release date:2010-01-19
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HSP70 (CGD2_20) FROM Cryptosporidium PARVUM IN COMPLEX WITH ADP and inorganic phosphate
To be Published
3L6Q
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HSP70 FROM CRYPTOSPORIDIUM PARVUM (CGD2_20)
Descriptor:Heat shock 70 (HSP70) protein, SULFATE ION, MAGNESIUM ION
Authors:Pizarro, J.C., Wernimont, A.K., Hutchinson, A., Sullivan, H., Lew, J., Bochkarev, A., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Hui, R., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2009-12-24
Release date:2010-02-02
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Crystal structure of the N-terminal domain of HSP70 from Cryptosporidium parvum (CGD2_20)
To be Published
3LIJ
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CRYSTAL STRUCTURE OF FULL LENGTH CPCDPK3 (CGD5_820) IN COMPLEX WITH CA2+ AND AMPPNP
Descriptor:Calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands, CALCIUM ION, MAGNESIUM ION, ...
Authors:Qiu, W., Hutchinson, A., Wernimont, A., Walker, J.R., Sullivan, H., Lin, Y.-H., Mackenzie, F., Kozieradzki, I., Cossar, D., Schapira, M., Senisterra, G., Vedadi, M., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Bochkarev, A., Hui, R., Amani, M., Structural Genomics Consortium (SGC)
Deposit date:2010-01-25
Release date:2010-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of full length CpCDPK3 (cgd5_820) in complex with Ca2+ and AMPPNP
To be Published
3LLT
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CRYSTAL STRUCTURE OF PF14_0431, KINASE DOMAIN.
Descriptor:Serine/threonine kinase-1, PfLammer, SULFATE ION, ...
Authors:Wernimont, A.K., Tempel, W., Lin, Y.H., Loppnau, P., MacKenzie, F., Sullivan, H., Weadge, J., Kozieradzki, I., Cossar, D., Sinesterra, G., Vedadi, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Hui, R., Qiu, W., Hutchinson, A., Structural Genomics Consortium (SGC)
Deposit date:2010-01-29
Release date:2010-08-04
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of PF14_0431, kinase domain.
TO BE PUBLISHED
3MSE
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CRYSTAL STRUCTURE OF C-TERMINAL DOMAIN OF PF110239.
Descriptor:Calcium-dependent protein kinase, putative, CALCIUM ION, ...
Authors:Wernimont, A.K., Artz, J.D., Hutchinson, A., Sullivan, H., Weadge, J., Tempel, W., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Lin, Y.H., Neculai, A.M., Amani, M., Structural Genomics Consortium (SGC)
Deposit date:2010-04-29
Release date:2010-06-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of C-terminal domain of PF110239
To be Published
3N72
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CRYSTAL STRUCTURE OF AHA-1 FROM PLASMODIUM FALCIPARUM, PFC0270W
Descriptor:putative activator of HSP90, THIOCYANATE ION
Authors:Wernimont, A.K., Dong, A., Hutchinson, A., Sullivan, H., Mackenzie, F., Kozieradzki, I., Cossar, D., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Pizarro, J.C., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2010-05-26
Release date:2010-07-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal Structure of Aha-1 from plasmodium falciparum, PFC0270w
To be Published
3N9X
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CRYSTAL STRUCTURE OF MAP KINASE FROM PLASMODIUM BERGHEI, PB000659.00.0
Descriptor:Phosphotransferase, GLYCEROL
Authors:Wernimont, A.K., Hutchinson, A., Sullivan, H., MacKenzie, F., Kozieradzki, I., Chau, I., Lew, J., Senisterra, G., Artz, J., Amani, M., Cossar, D., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2010-05-31
Release date:2010-07-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of Map Kinase from plasmodium berghei, PB000659.00.0
To be Published
3NI8
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CRYSTAL STRUCTURE OF PFC0360W, AN HSP90 ACTIVATOR FROM PLASMODIUM FALCIPARUM
Descriptor:PFC0360w protein, ISOPROPYL ALCOHOL, GLYCEROL
Authors:Wernimont, A.K., Hutchinson, A., Sullivan, H., MacKenzie, F., Kozieradzki, I., Cossar, D., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Pizzaro, J.C., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2010-06-15
Release date:2010-08-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of PFC0360w, an HSP90 activator from plasmodium falciparum
To be Published
3NIE
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CRYSTAL STRUCTURE OF PF11_0147
Descriptor:MAP2 kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Wernimont, A.K., Hutchinson, A., Sullivan, H., MacKenzie, F., Kozieradzki, I., Chau, I., Lew, J., Senisterra, G., Cossar, D., Amani, M., Artz, J.D., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2010-06-15
Release date:2010-08-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of PF11_0147
To be Published
3O4Y
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CRYSTAL STRUCTURE OF CAD DOMAIN OF THE PLASMODIUM VIVAX CDPK, PVX_11610
Descriptor:Calcium-dependent protein kinase 3, CALCIUM ION, GLYCEROL, ...
Authors:Wernimont, A.K., Hutchinson, A., Sullivan, H., Weadge, J., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Amani, M., Structural Genomics Consortium (SGC)
Deposit date:2010-07-27
Release date:2010-08-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of CAD domain of the Plasmodium Vivax CDPK, PVX_11610
TO BE PUBLISHED
3OZ6
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CRYSTAL STRUCTURE OF MAPK FROM CRYPTOSPORIDIUM PARVUM, CGD2_1960
Descriptor:Mitogen-activated protein kinase 1, serine/threonine protein kinase, GLYCEROL
Authors:Wernimont, A.K., Lew, J., Lin, Y.H., Sullivan, H., Hassanali, A., Kozieradzki, I., Cossar, D., Arrowsmith, C.H., Bochkarev, A., Bountra, C., Edwards, A.M., Weigelt, J., Hui, R., Neculai, A.M., Hutchinson, A., Structural Genomics Consortium (SGC)
Deposit date:2010-09-24
Release date:2010-12-08
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Crystal structure of MapK from Cryptosporidium Parvum, cgd2_1960
To be Published
3Q5I
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CRYSTAL STRUCTURE OF PBANKA_031420
Descriptor:Protein kinase, CALCIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Wernimont, A.K., Hutchinson, A., Sullivan, H., Panico, E., Crombet, L., Cossar, D., Hassani, A., Vedadi, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Neculai, A.M., Amani, M., Structural Genomics Consortium (SGC)
Deposit date:2010-12-28
Release date:2011-06-01
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of CDPK1 from Plasmodium Bergheii, PBANKA_031420
To be Published
3O6O
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF AN HSP90 FROM TRYPANOSOMA BRUCEI, TB10.26.1080 IN THE PRESENCE OF AN THE INHIBITOR BIIB021
Descriptor:Heat shock protein 83, 6-chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-9H-purin-2-amine, PENTAETHYLENE GLYCOL
Authors:Wernimont, A.K., Hutchinson, A., Sullivan, H., Weadge, J., Li, Y., Kozieradzki, I., Cossar, D., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Wyatt, P., Fairlamb, A.H., Ferguson, M.A.J., Thompson, S., MacKenzie, C., Hui, R., Pizarro, J.C., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2010-07-29
Release date:2010-08-18
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Exploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug design.
PLoS Negl Trop Dis, 7, 2013
3OMU
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF AN HSP90 FROM TRYPANOSOMA BRUCEI, TB10.26.1080 IN THE PRESENCE OF A THIENOPYRIMIDINE DERIVATIVE
Descriptor:Heat shock protein 83, 2-amino-4-{2,4-dichloro-5-[2-(diethylamino)ethoxy]phenyl}-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide
Authors:Wernimont, A.K., Hutchinson, A., Sullivan, H., Weadge, J., Cossar, D., Li, Y., Kozieradzki, I., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Wyatt, P.G., Fairlamb, A.H., MacKenzie, C., Ferguson, M.A.J., Hui, R., Pizarro, J.C., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2010-08-27
Release date:2010-10-27
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Exploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug design.
PLoS Negl Trop Dis, 7, 2013
3OPD
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF AN HSP90 FROM TRYPANOSOMA BRUCEI, TB10.26.1080 IN THE PRESENCE OF A BENZAMIDE DERIVATIVE
Descriptor:Heat shock protein 83, 4-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]-2-[(cis-4-hydroxycyclohexyl)amino]benzamide
Authors:Pizarro, J.C., Wernimont, A.K., Hutchinson, A., Sullivan, H., Chamberlain, K., Weadge, J., Cossar, D., Li, Y., Kozieradzki, I., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Wyatt, P.G., Fairlamb, A.H., MacKenzie, C., Ferguson, M.A.J., Hui, R., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2010-08-31
Release date:2010-10-13
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Exploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug design.
PLoS Negl Trop Dis, 7, 2013