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3HBN
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BU of 3hbn by Molmil
Crystal structure PseG-UDP complex from Campylobacter jejuni
Descriptor: CHLORIDE ION, GLYCEROL, UDP-sugar hydrolase, ...
Authors:Rangarajan, E.S, Proteau, A, Cygler, M, Matte, A, Sulea, T, Schoenhofen, I.C.
Deposit date:2009-05-04
Release date:2009-05-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and functional analysis of Campylobacter jejuni PseG: a udp-sugar hydrolase from the pseudaminic acid biosynthetic pathway.
J.Biol.Chem., 284, 2009
1ZPS
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BU of 1zps by Molmil
Crystal structure of Methanobacterium thermoautotrophicum phosphoribosyl-AMP cyclohydrolase HisI
Descriptor: ACETIC ACID, CADMIUM ION, Phosphoribosyl-AMP cyclohydrolase
Authors:Sivaraman, J, Myers, R.S, Boju, L, Sulea, T, Cygler, M, Davisson, V.J, Schrag, J.D, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2005-05-17
Release date:2005-08-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Methanobacterium thermoautotrophicum Phosphoribosyl-AMP Cyclohydrolase HisI.
Biochemistry, 44, 2005
1MHW
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BU of 1mhw by Molmil
Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides
Descriptor: 4-biphenylacetyl-Cys-(D)Arg-Tyr-N-(2-phenylethyl) amide, Cathepsin L
Authors:Chowdhury, S, Sivaraman, J, Wang, J, Devanathan, G, Lachance, P, Qi, H, Menard, R, Lefebvre, J, Konishi, Y, Cygler, M, Sulea, T, Purisima, E.O.
Deposit date:2002-08-21
Release date:2002-12-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides
J.Med.Chem., 45, 2002
1NQC
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BU of 1nqc by Molmil
Crystal structures of Cathepsin S inhibitor complexes
Descriptor: Cathepsin S, N-[(1R)-2-(BENZYLSULFANYL)-1-FORMYLETHYL]-N-(MORPHOLIN-4-YLCARBONYL)-L-PHENYLALANINAMIDE
Authors:Pauly, T.A, Sulea, T, Ammirati, M, Sivaraman, J, Danley, D.E, Griffor, M.C, Kamath, A.V, Wang, I.K, Laird, E.R, Menard, R, Cygler, M, Rath, V.L.
Deposit date:2003-01-21
Release date:2003-04-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Specificity determinants of human cathepsin s revealed by crystal structures of complexes.
Biochemistry, 42, 2003
1NPZ
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BU of 1npz by Molmil
Crystal structures of Cathepsin S inhibitor complexes
Descriptor: Cathepsin S, N~2~-(morpholin-4-ylcarbonyl)-N-[(3S)-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]-L-leucinamide
Authors:Pauly, T.A, Sulea, T, Ammirati, M, Sivaraman, J, Danley, D.E, Griffor, M.C, Kamath, A.V, Wang, I.K, Laird, E.R, Seddon, A.P, Menard, R, Cygler, M, Rath, V.L.
Deposit date:2003-01-20
Release date:2003-04-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Specificity determinants of human cathepsin s revealed by crystal structures of complexes.
Biochemistry, 42, 2003
1QD1
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BU of 1qd1 by Molmil
THE CRYSTAL STRUCTURE OF THE FORMIMINOTRANSFERASE DOMAIN OF FORMIMINOTRANSFERASE-CYCLODEAMINASE.
Descriptor: FORMIMINOTRANSFERASE-CYCLODEAMINASE, GLYCEROL, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid
Authors:Kohls, D, Sulea, T, Purisima, E, MacKenzie, R.E, Vrielink, A.
Deposit date:1999-07-08
Release date:2000-01-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure of the formiminotransferase domain of formiminotransferase-cyclodeaminase: implications for substrate channeling in a bifunctional enzyme.
Structure Fold.Des., 8, 2000
2FS5
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BU of 2fs5 by Molmil
Crystal structure of TDP-fucosamine acetyltransferase (WecD)- apo form
Descriptor: TDP-Fucosamine acetyltransferase, ZINC ION
Authors:Hung, M.N, Rangarajan, E, Munger, C, Nadeau, G, Sulea, T, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2006-01-20
Release date:2006-08-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of TDP-Fucosamine Acetyltransferase (WecD) from Escherichia coli, an Enzyme Required for Enterobacterial Common Antigen Synthesis.
J.Bacteriol., 188, 2006
2FT0
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BU of 2ft0 by Molmil
Crystal structure of TDP-fucosamine acetyltransferase (WecD)- complex with acetyl-CoA
Descriptor: ACETYL COENZYME *A, TDP-fucosamine acetyltransferase
Authors:Hung, M.N, Rangarajan, E, Munger, C, Nadeau, G, Sulea, T, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2006-01-23
Release date:2006-08-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Crystal Structure of TDP-Fucosamine Acetyltransferase (WecD) from Escherichia coli, an Enzyme Required for Enterobacterial Common Antigen Synthesis.
J.Bacteriol., 188, 2006
2VHE
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BU of 2vhe by Molmil
PglD-CoA complex: An acetyl transferase from Campylobacter jejuni
Descriptor: ACETYLTRANSFERASE, COENZYME A, SULFATE ION
Authors:Rangarajan, E.S, Ruane, K.M, Sulea, T, Watson, D.C, Proteau, A, Leclerc, S, Cygler, M, Matte, A, Young, N.M.
Deposit date:2007-11-21
Release date:2008-01-29
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and Active Site Residues of Pgld, an N-Acetyltransferase from the Bacillosamine Synthetic Pathway Required for N-Glycan Synthesis in Campylobacter Jejuni
Biochemistry, 47, 2008
3HBM
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BU of 3hbm by Molmil
Crystal Structure of PseG from Campylobacter jejuni
Descriptor: SULFATE ION, UDP-sugar hydrolase
Authors:Rangarajan, E.S, Proteau, A, Cygler, M, Matte, A, Sulea, T, Schoenhofen, I.C.
Deposit date:2009-05-04
Release date:2009-05-26
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional analysis of Campylobacter jejuni PseG: a udp-sugar hydrolase from the pseudaminic acid biosynthetic pathway.
J.Biol.Chem., 284, 2009
4EEC
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BU of 4eec by Molmil
Crystal Structure of the glycopeptide antibiotic sulfotransferase StaL complexed with A3P and desulfo-A47934.
Descriptor: ADENOSINE-3'-5'-DIPHOSPHATE, StaL, desulfo-A47934
Authors:Shi, R, Cygler, M.
Deposit date:2012-03-28
Release date:2012-07-04
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of sulfonation of the glycopeptide antibiotic scaffold by the sulfotransferase StaL
Proc.Natl.Acad.Sci.USA, 2012
7KEZ
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BU of 7kez by Molmil
Crystal structure of bH1 Fab variant (CDR H3 loop design 16_0325) in complex with VEGF
Descriptor: CHLORIDE ION, Isoform L-VEGF206 of Vascular endothelial growth factor A, anti-VEGF-A Fab bH1 heavy chain, ...
Authors:Shi, R, Manenda, M.S, Picard, M.-E.
Deposit date:2020-10-13
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal structure of bH1 Fab CDR H3 loop variants in apo form and in complex with VEGF
to be published
7KF0
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BU of 7kf0 by Molmil
Crystal structure of bH1 Fab variant (CDR H3 loop design 13_0346) in complex with VEGF
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Isoform L-VEGF206 of Vascular endothelial growth factor A, ...
Authors:Shi, R, Picard, M.-E.
Deposit date:2020-10-13
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Crystal structure of bH1 Fab CDR H3 loop variants in apo form and in complex with VEGF
to be published
7KF1
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BU of 7kf1 by Molmil
Crystal structure of bH1 Fab variant (CDR H3 loop design 14_0130) in complex with VEGF
Descriptor: CHLORIDE ION, Isoform L-VEGF206 of Vascular endothelial growth factor A, anti-VEGF-A Fab bH1 heavy chain, ...
Authors:Shi, R, Picard, M.-E, Manenda, M.S.
Deposit date:2020-10-13
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of bH1 Fab CDR H3 loop variants in apo form and in complex with VEGF
to be published
6MXS
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BU of 6mxs by Molmil
Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98F,HC-G99M]
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ...
Authors:Shi, R, Picard, M.-E, Manenda, M.S.
Deposit date:2018-10-31
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Binding symmetry and surface flexibility mediate antibody self-association.
Mabs, 11, 2019
6MY5
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BU of 6my5 by Molmil
Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98F,HC-G99M,LC-S30bR]
Descriptor: 1,2-ETHANEDIOL, anti-VEGF-A Fab fragment bH1 heavy chain, anti-VEGF-A Fab fragment bH1 light chain
Authors:Shi, R.
Deposit date:2018-11-01
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Binding symmetry and surface flexibility mediate antibody self-association.
Mabs, 11, 2019
2ZL1
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BU of 2zl1 by Molmil
MP1-p14 Scaffolding complex
Descriptor: Mitogen-activated protein kinase kinase 1-interacting protein 1, Mitogen-activated protein-binding protein-interacting protein
Authors:Schrag, J.D, Cygler, M, Munger, C, Magloire, A.
Deposit date:2008-04-02
Release date:2008-06-24
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular dynamics-solvated interaction energy studies of protein-protein interactions: the MP1-p14 scaffolding complex.
J.Mol.Biol., 379, 2008
5TX4
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BU of 5tx4 by Molmil
Derivative of mouse TGF-beta2, with a deletion of residues 52-71 and K25R, R26K, L51R, A74K, C77S, L89V, I92V, K94R T95K, I98V single amino acid substitutions, bound to human TGF-beta type II receptor ectodomain residues 15-130
Descriptor: TGF-beta receptor type-2, Transforming growth factor beta-2
Authors:Hinck, A.P, Kim, S.
Deposit date:2016-11-15
Release date:2017-03-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.876 Å)
Cite:An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
J. Biol. Chem., 292, 2017
5TX6
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BU of 5tx6 by Molmil
Structure of TGF-beta2 derivative with deletion of residues 52-71 and 10 single amino acid mutations (mmTGF-beta2-7M)
Descriptor: CALCIUM ION, Transforming growth factor beta-2
Authors:Petrunak, E.M, Hinck, A.P.
Deposit date:2016-11-15
Release date:2017-03-01
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.746 Å)
Cite:An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
J. Biol. Chem., 292, 2017
5TX2
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BU of 5tx2 by Molmil
Miniature TGF-beta2 3-mutant monomer
Descriptor: Transforming growth factor beta-2
Authors:Taylor, A.B, Kim, S.K, Hart, P.J, Hinck, A.P.
Deposit date:2016-11-15
Release date:2017-03-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
J. Biol. Chem., 292, 2017
1OFM
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BU of 1ofm by Molmil
CRYSTAL STRUCTURE OF CHONDROITINASE B COMPLEXED TO CHONDROITIN 4-SULFATE TETRASACCHARIDE
Descriptor: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, CHONDROITINASE B, alpha-D-galactopyranose-(1-3)-[beta-D-glucopyranose-(1-4)]2-O-methyl-alpha-L-fucopyranose-(1-4)-beta-D-xylopyranose-(1-4)-alpha-D-glucopyranuronic acid-(1-2)-[alpha-L-rhamnopyranose-(1-4)]alpha-D-mannopyranose
Authors:Michel, G, Cygler, M.
Deposit date:2003-04-15
Release date:2004-04-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Structure of Chondroitin B Lyase Complexed with Glycosaminoglycan Oligosaccharides Unravels a Calcium-Dependent Catalytic Machinery
J.Biol.Chem., 279, 2004
1OFL
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BU of 1ofl by Molmil
CRYSTAL STRUCTURE OF CHONDROITINASE B COMPLEXED TO DERMATAN SULFATE HEXASACCHARIDE
Descriptor: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-alpha-D-galactopyranose, 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, CALCIUM ION, ...
Authors:Michel, G, Cygler, M.
Deposit date:2003-04-15
Release date:2004-06-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Structure of Chondroitin B Lyase Complexed with Glycosaminoglycan Oligosaccharides Unravels a Calcium-Dependent Catalytic Machinery
J.Biol.Chem., 279, 2004
6MXR
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BU of 6mxr by Molmil
Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98M,HC-G99M]
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ...
Authors:Shi, R.
Deposit date:2018-10-31
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Binding symmetry and surface flexibility mediate antibody self-association.
Mabs, 11, 2019
6MY4
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BU of 6my4 by Molmil
Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98M,HC-G99M,LC-S30bR]
Descriptor: 1,2-ETHANEDIOL, anti-VEGF-A Fab fragment bH1 heavy chain, anti-VEGF-A Fab fragment bH1 light chain
Authors:Shi, R, Picard, M.-E, Manenda, M.
Deposit date:2018-11-01
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Binding symmetry and surface flexibility mediate antibody self-association.
Mabs, 11, 2019
6I9J
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BU of 6i9j by Molmil
Human transforming growth factor beta2 in a tetragonal crystal form
Descriptor: Transforming growth factor beta-2 proprotein
Authors:Gomis-Ruth, F.X, Marino-Puertas, L, del Amo-Maestro, L, Goulas, T.
Deposit date:2018-11-23
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor beta 2 in a new conformation.
Sci Rep, 9, 2019

 

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