Author results

1ICH
  • Download 1ich
  • View 1ich
Molmil generated image of 1ich
SOLUTION STRUCTURE OF THE TUMOR NECROSIS FACTOR RECEPTOR-1 DEATH DOMAIN
Descriptor:TUMOR NECROSIS FACTOR RECEPTOR-1
Authors:Sukits, S.F., Lin, L.-L., Malakian, K., Powers, R., Xu, G.-Y.
Deposit date:2001-04-01
Release date:2002-04-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the tumor necrosis factor receptor-1 death domain.
J.Mol.Biol., 310, 2001
2GC8
  • Download 2gc8
  • View 2gc8
Molmil generated image of 2gc8
STRUCTURE OF A PROLINE SULFONAMIDE INHIBITOR BOUND TO HCV NS5B POLYMERASE
Descriptor:RNA-directed RNA polymerase, 1-[(2-AMINO-4-CHLORO-5-METHYLPHENYL)SULFONYL]-L-PROLINE
Authors:Gopalsamy, A., Chopra, R., Lim, K., Ciszewski, G., Shi, M., Curran, K.J., Sukits, S.F., Svenson, K., Bard, J., Ellingboe, J.W., Agarwal, A., Krishnamurthy, G., Howe, A.Y., Orlowski, M., Feld, B., O'connell, J., Mansour, T.S.
Deposit date:2006-03-13
Release date:2006-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of Proline Sulfonamides as Potent and Selective Hepatitis C Virus NS5b Polymerase Inhibitors. Evidence for a New NS5b Polymerase Binding Site.
J.Med.Chem., 49, 2006