Author results

1B4U
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PROTOCATECHUATE 4,5-DIOXYGENASE (LIGAB) IN COMPLEX WITH PROTOCATECHUATE (PCA)
Descriptor:PROTOCATECHUATE 4,5-DIOXYGENASE, FE (III) ION, 3,4-DIHYDROXYBENZOIC ACID
Authors:Sugimoto, K., Senda, T., Mitsui, Y.
Deposit date:1998-12-29
Release date:1999-08-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of an aromatic ring opening dioxygenase LigAB, a protocatechuate 4,5-dioxygenase, under aerobic conditions.
Structure Fold.Des., 7, 1999
1BOU
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THREE-DIMENSIONAL STRUCTURE OF LIGAB
Descriptor:4,5-DIOXYGENASE ALPHA CHAIN, 4,5-DIOXYGENASE BETA CHAIN, FE (III) ION
Authors:Sugimoto, K., Senda, T., Fukuda, M., Mitsui, Y.
Deposit date:1998-08-06
Release date:1999-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of an aromatic ring opening dioxygenase LigAB, a protocatechuate 4,5-dioxygenase, under aerobic conditions.
Structure, 7, 1999
3WKU
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CRYSTAL STRUCTURE OF THE ANAEROBIC DESB-GALLATE COMPLEX
Descriptor:Gallate dioxygenase, FE (III) ION, 3,4,5-trihydroxybenzoic acid
Authors:Sugimoto, K., Senda, M., Kasai, D., Fukuda, M., Masai, E., Senda, T.
Deposit date:2013-10-31
Release date:2014-04-30
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular Mechanism of Strict Substrate Specificity of an Extradiol Dioxygenase, DesB, Derived from Sphingobium sp. SYK-6
Plos One, 9, 2014
3WPM
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CRYSTAL STRUCTURE OF THE ANAEROBIC DESB-GALLATE COMPLEX BY CO-CRYSTALLIZATION
Descriptor:Gallate dioxygenase, FE (III) ION, 3,4,5-trihydroxybenzoic acid
Authors:Sugimoto, K., Senda, M., Kasai, D., Fukuda, M., Masai, E., Senda, T.
Deposit date:2014-01-14
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular Mechanism of Strict Substrate Specificity of an Extradiol Dioxygenase, DesB, Derived from Sphingobium sp. SYK-6
Plos One, 9, 2014
3WR3
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CRYSTAL STRUCTURE OF THE ANAEROBIC DESB-GALLATE COMPLEX
Descriptor:Gallate dioxygenase, FE (II) ION, 3,4,5-trihydroxybenzoic acid
Authors:Sugimoto, K., Senda, M., Kasai, D., Fukuda, M., Masai, E., Senda, T.
Deposit date:2014-02-13
Release date:2014-04-30
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular Mechanism of Strict Substrate Specificity of an Extradiol Dioxygenase, DesB, Derived from Sphingobium sp. SYK-6
Plos One, 9, 2014
3WR4
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CRYSTAL STRUCTURE OF THE ANAEROBIC DESB-GALLATE COMPLEX
Descriptor:Gallate dioxygenase, FE (III) ION, 3,4,5-trihydroxybenzoic acid
Authors:Sugimoto, K., Senda, M., Kasai, D., Fukuda, M., Masai, E., Senda, T.
Deposit date:2014-02-13
Release date:2014-04-30
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular Mechanism of Strict Substrate Specificity of an Extradiol Dioxygenase, DesB, Derived from Sphingobium sp. SYK-6
Plos One, 9, 2014
3WR8
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CRYSTAL STRUCTURE OF DESB FROM SPHINGOBIUM SP. STRAIN SYK-6
Descriptor:Gallate dioxygenase, FE (II) ION
Authors:Sugimoto, K., Senda, M., Kasai, D., Fukuda, M., Masai, E., Senda, T.
Deposit date:2014-02-21
Release date:2014-04-30
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Molecular Mechanism of Strict Substrate Specificity of an Extradiol Dioxygenase, DesB, Derived from Sphingobium sp. SYK-6
Plos One, 9, 2014
3WR9
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CRYSTAL STRUCTURE OF THE ANAEROBIC DESB-GALLATE COMPLEX
Descriptor:Gallate dioxygenase, FE (II) ION, 3,4,5-trihydroxybenzoic acid
Authors:Sugimoto, K., Senda, M., Kasai, D., Fukuda, M., Masai, E., Senda, T.
Deposit date:2014-02-21
Release date:2014-04-30
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular Mechanism of Strict Substrate Specificity of an Extradiol Dioxygenase, DesB, Derived from Sphingobium sp. SYK-6
Plos One, 9, 2014
3WRA
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CRYSTAL STRUCTURE OF THE DESB-GALLATE COMPLEX EXPOSED TO AEROBIC ATOMOSPHERE
Descriptor:Gallate dioxygenase, FE (II) ION
Authors:Sugimoto, K., Senda, M., Kasai, D., Fukuda, M., Masai, E., Senda, T.
Deposit date:2014-02-21
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular Mechanism of Strict Substrate Specificity of an Extradiol Dioxygenase, DesB, Derived from Sphingobium sp. SYK-6
Plos One, 9, 2014
3WRB
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CRYSTAL STRUCTURE OF THE ANAEROBIC H124F DESB-GALLATE COMPLEX
Descriptor:Gallate dioxygenase, FE (II) ION, 3,4,5-trihydroxybenzoic acid
Authors:Sugimoto, K., Senda, M., Kasai, D., Fukuda, M., Masai, E., Senda, T.
Deposit date:2014-02-21
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular Mechanism of Strict Substrate Specificity of an Extradiol Dioxygenase, DesB, Derived from Sphingobium sp. SYK-6
Plos One, 9, 2014
3WRC
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CRYSTAL STRUCTURE OF THE ANAEROBIC DESB-PROTOCATECHUATE (PCA) COMPLEX
Descriptor:Gallate dioxygenase, FE (II) ION, 3,4-DIHYDROXYBENZOIC ACID
Authors:Sugimoto, K., Senda, M., Kasai, D., Fukuda, M., Masai, E., Senda, T.
Deposit date:2014-02-21
Release date:2014-04-30
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular Mechanism of Strict Substrate Specificity of an Extradiol Dioxygenase, DesB, Derived from Sphingobium sp. SYK-6
Plos One, 9, 2014
1KW3
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CRYSTAL STRUCTURE OF 2,3-DIHYDROXYBIPHENYAL DIOXYGENASE (BPHC) AT 1.45 A RESOLUTION
Descriptor:2,3-Dihydroxybiphenyl dioxygenase, FE (II) ION, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Sato, N., Uragami, Y., Nishizaki, T., Takahashi, Y., Sazaki, G., Sugimoto, K., Nonaka, T., Masai, E., Fukuda, M., Senda, T.
Deposit date:2002-01-28
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal Structures of the Reaction Intermediate and its Homologue of an Extradiol-cleaving Catecholic Dioxygenase
J.Mol.Biol., 321, 2002
1KW6
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CRYSTAL STRUCTURE OF 2,3-DIHYDROXYBIPHENYL DIOXYGENASE (BPHC) IN COMPLEX WITH 2,3-DIHYDROXYBIPHENYL AT 1.45 A RESOLUTION
Descriptor:2,3-Dihydroxybiphenyl dioxygenase, FE (II) ION, BIPHENYL-2,3-DIOL, ...
Authors:Sato, N., Uragami, Y., Nishizaki, T., Takahashi, Y., Sazaki, G., Sugimoto, K., Nonaka, T., Masai, E., Fukuda, M., Senda, T.
Deposit date:2002-01-28
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal Structures of the Reaction Intermediate and its Homologue of an Extradiol-cleaving Catecholic Dioxygenase
J.Mol.Biol., 321, 2002
1KW8
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CRYSTAL STRUCTURE OF BPHC-2,3-DIHYDROXYBIPHENYL-NO COMPLEX
Descriptor:2,3-Dihydroxybiphenyl dioxygenase, FE (II) ION, NITRIC OXIDE, ...
Authors:Sato, N., Uragami, Y., Nishizaki, T., Takahashi, Y., Sazaki, G., Sugimoto, K., Nonaka, T., Masai, E., Fukuda, M., Senda, T.
Deposit date:2002-01-29
Release date:2003-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of the Reaction Intermediate and its Homologue of an Extradiol-cleaving Catecholic Dioxygenase
J.Mol.Biol., 321, 2002
1KW9
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CRYSTAL STRUCTURE OF 2,3-DIHYDROXYBIPHENYL DIOXYGENASE (BPHC) IN COMPLEX WITH 2,3-DIHYDROXYBIPHENYL AT 2.0A RESOLUTION
Descriptor:2,3-Dihydroxybiphenyl dioxygenase, FE (II) ION, BIPHENYL-2,3-DIOL
Authors:Sato, N., Uragami, Y., Nishizaki, T., Takahashi, Y., Sazaki, G., Sugimoto, K., Nonaka, T., Masai, E., Fukuda, M., Senda, T.
Deposit date:2002-01-29
Release date:2003-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structures of the Reaction Intermediate and its Homologue of an Extradiol-cleaving Catecholic Dioxygenase
J.Mol.Biol., 321, 2002
1KWB
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CRYSTAL STRUCTURE OF THE HIS145ALA MUTANT OF 2,3-DIHYDROXYBIPHENY DIOXYGENASE (BPHC)
Descriptor:2,3-Dihydroxybiphenyl dioxygenase
Authors:Sato, N., Uragami, Y., Nishizaki, T., Takahashi, Y., Sazaki, G., Sugimoto, K., Nonaka, T., Masai, E., Fukuda, M., Senda, T.
Deposit date:2002-01-29
Release date:2003-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of the Reaction Intermediate and its Homologue of an Extradiol-cleaving Catecholic Dioxygenase
J.Mol.Biol., 321, 2002
1KWC
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THE HIS145ALA MUTANT OF 2,3-DIHYDROXYBIPHENYL DIOXYGENASE IN COMPLEX WITH 2,3-DIHYDROXYBIPHENYL
Descriptor:2,3-dihydroxybiphenyl dioxygenase, BIPHENYL-2,3-DIOL
Authors:Sato, N., Uragami, Y., Nishizaki, T., Takahashi, Y., Sazaki, G., Sugimoto, K., Nonaka, T., Masai, E., Fukuda, M., Senda, T.
Deposit date:2002-01-29
Release date:2003-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of the Reaction Intermediate and its Homologue of an Extradiol-cleaving Catecholic Dioxygenase
J.Mol.Biol., 321, 2002
1QG7
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STROMA CELL-DERIVED FACTOR-1ALPHA (SDF-1ALPHA)
Descriptor:STROMAL CELL-DERIVED FACTOR 1 ALPHA, SULFATE ION
Authors:Senda, T., Nandhagopal, N., Sugimoto, K., Mitsui, Y.
Deposit date:1999-04-21
Release date:2001-02-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of recombinant native SDF-1alpha with additional mutagenesis studies: an attempt at a more comprehensive interpretation of accumulated structure-activity relationship data.
J.Interferon Cytokine Res., 20, 2000
3VQS
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CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE WITH A NOVEL PIPERAZINE INHIBITOR
Descriptor:RNA-directed RNA polymerase, (2R)-4-(5-cyclopropyl[1,3]thiazolo[4,5-d]pyrimidin-2-yl)-N-[3-fluoro-4-(trifluoromethoxy)benzyl]-1-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine-2-carboxamide, CHLORIDE ION
Authors:Adachi, T., Doi, S., Ando, I., Sugimoto, K., Orita, T., Nomura, A., Kamada, M.
Deposit date:2012-03-30
Release date:2012-08-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Preclinical Characterization of JTK-853, a Novel Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase.
Antimicrob.Agents Chemother., 56, 2012
4KNR
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HIN GLMU BOUND TO WG188
Descriptor:Bifunctional protein GlmU, N-{4-[(2-benzyl-7-hydroxy-6-methoxyquinazolin-4-yl)amino]phenyl}benzamide, TETRAETHYLENE GLYCOL, ...
Authors:Doig, P., Kazmirski, S.L., Boriack-Sjodin, P.A.
Deposit date:2013-05-10
Release date:2014-10-15
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping.
Bioorg.Med.Chem., 22, 2014
4KNX
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HIN GLMU BOUND TO WG176
Descriptor:Bifunctional protein GlmU, [(4-{[4-(benzoylamino)phenyl]amino}-6-methoxyquinazolin-7-yl)oxy]acetic acid, TETRAETHYLENE GLYCOL, ...
Authors:Doig, P., Kazmirski, S.L., Boriack-Sjodin, P.A.
Deposit date:2013-05-10
Release date:2014-10-15
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping.
Bioorg.Med.Chem., 22, 2014
4KPX
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HIN GLMU BOUND TO WG766
Descriptor:Bifunctional protein GlmU, SULFATE ION, MAGNESIUM ION, ...
Authors:Doig, P., Kazmirski, S.L., Boriack-Sjodin, P.A.
Deposit date:2013-05-14
Release date:2014-10-15
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping.
Bioorg.Med.Chem., 22, 2014
4KPZ
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HIN GLMU BOUND TO A SMALL MOLECULE FRAGMENT
Descriptor:Bifunctional protein GlmU, 1-(3-nitrophenyl)dihydropyrimidine-2,4(1H,3H)-dione, SULFATE ION, ...
Authors:Doig, P., Kazmirski, S.L., Boriack-Sjodin, P.A.
Deposit date:2013-05-14
Release date:2014-10-15
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping.
Bioorg.Med.Chem., 22, 2014
4KQL
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HIN GLMU BOUND TO WG578
Descriptor:Bifunctional protein GlmU, SULFATE ION, MAGNESIUM ION, ...
Authors:Doig, P., Kazmirski, S.L., Boriack-Sjodin, P.A.
Deposit date:2013-05-15
Release date:2014-10-15
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping.
Bioorg.Med.Chem., 22, 2014
1EIL
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2,3-DIHYDROXYBIPHENYL-1,2-DIOXYGENASE
Descriptor:2,3-DIHYDROXYBIPHENYL 1,2-DIOXYGENASE, SULFATE ION, FE (III) ION
Authors:Senda, T.
Deposit date:2000-02-26
Release date:2001-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of substrate free and complex forms of reactivated BphC, an extradiol type ring-cleavage dioxygenase.
J.Inorg.Biochem., 83, 2001
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