Author results

1DPT
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D-DOPACHROME TAUTOMERASE
Descriptor:D-DOPACHROME TAUTOMERASE
Authors:Sugimoto, H., Taniguchi, M., Nakagawa, A., Tanaka, I.
Deposit date:1998-05-11
Release date:1999-03-30
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Crystal structure of human D-dopachrome tautomerase, a homologue of macrophage migration inhibitory factor, at 1.54 A resolution.
Biochemistry, 38, 1999
1V5H
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CRYSTAL STRUCTURE OF HUMAN CYTOGLOBIN (FERRIC FORM)
Descriptor:Cytoglobin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sugimoto, H., Makino, M., Sawai, H., Kawada, N., Yoshizato, K., Shiro, Y., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-11-23
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of human cytoglobin for ligand binding.
J.Mol.Biol., 339, 2004
2D0T
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CRYSTAL STRUCTURE OF 4-PHENYLIMIDAZOLE BOUND FORM OF HUMAN INDOLEAMINE 2,3-DIOXYGENASE
Descriptor:Indoleamine 2,3-dioxygenase, PROTOPORPHYRIN IX CONTAINING FE, 4-PHENYL-1H-IMIDAZOLE, ...
Authors:Sugimoto, H., Oda, S., Otsuki, T., Hino, T., Yoshida, T., Shiro, Y., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-08-08
Release date:2006-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of human indoleamine 2,3-dioxygenase: catalytic mechanism of O2 incorporation by a heme-containing dioxygenase.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2D0U
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CRYSTAL STRUCTURE OF CYANIDE BOUND FORM OF HUMAN INDOLEAMINE 2,3-DIOXYGENASE
Descriptor:Indoleamine 2,3-dioxygenase, CYANIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Sugimoto, H., Oda, S., Otsuki, T., Hino, T., Yoshida, T., Shiro, Y., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-08-08
Release date:2006-01-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structure of human indoleamine 2,3-dioxygenase: catalytic mechanism of O2 incorporation by a heme-containing dioxygenase.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2ZBX
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CRYSTAL STRUCTURE OF VITAMIN D HYDROXYLASE CYTOCHROME P450 105A1 (WILD TYPE) WITH IMIDAZOLE BOUND
Descriptor:Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE, IMIDAZOLE
Authors:Sugimoto, H., Shinkyo, R., Hayashi, K., Yoneda, S., Yamada, M., Kamakura, M., Ikushiro, S., Shiro, Y., Sakaki, T.
Deposit date:2007-10-30
Release date:2008-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1alpha,25-Dihydroxyvitamin D3
Biochemistry, 47, 2008
2ZBY
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CRYSTAL STRUCTURE OF VITAMIN D HYDROXYLASE CYTOCHROME P450 105A1 (R84A MUTANT)
Descriptor:Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sugimoto, H., Shinkyo, R., Hayashi, K., Yoneda, S., Yamada, M., Kamakura, M., Ikushiro, S., Shiro, Y., Sakaki, T.
Deposit date:2007-10-30
Release date:2008-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1alpha,25-Dihydroxyvitamin D3
Biochemistry, 47, 2008
2ZBZ
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CRYSTAL STRUCTURE OF VITAMIN D HYDROXYLASE CYTOCHROME P450 105A1 (R84A MUTANT) IN COMPLEX WITH 1,25-DIHYDROXYVITAMIN D3
Descriptor:Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE, 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL
Authors:Sugimoto, H., Shinkyo, R., Hayashi, K., Yoneda, S., Yamada, M., Kamakura, M., Ikushiro, S., Shiro, Y., Sakaki, T.
Deposit date:2007-10-30
Release date:2008-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1alpha,25-Dihydroxyvitamin D3
Biochemistry, 47, 2008
4U72
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CRYSTAL STRUCTURE OF 4-PHENYLIMIDAZOLE BOUND FORM OF HUMAN INDOLEAMINE 2,3-DIOXYGENASE (A260G MUTANT)
Descriptor:Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, 4-PHENYL-1H-IMIDAZOLE, ...
Authors:Sugimoto, H., Horitani, M., Kometani, E., Shiro, Y.
Deposit date:2014-07-30
Release date:2015-09-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformation and Mobility of Active Site Loop is Critical for Substrate Binding and Inhibition in Human Indoleamine 2,3-Dioxygenase
to be published
4U74
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CRYSTAL STRUCTURE OF 4-PHENYLIMIDAZOLE BOUND FORM OF HUMAN INDOLEAMINE 2,3-DIOXYGENASE (G262A MUTANT)
Descriptor:Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, 4-PHENYL-1H-IMIDAZOLE, ...
Authors:Sugimoto, H., Horitani, M., Kometani, E., Shiro, Y.
Deposit date:2014-07-30
Release date:2015-09-02
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Conformation and Mobility of Active Site Loop is Critical for Substrate Binding and Inhibition in Human Indoleamine 2,3-Dioxygenase
to be published
5GUW
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COMPLEX OF CYTOCHROME CD1 NITRITE REDUCTASE AND NITRIC OXIDE REDUCTASE IN DENITRIFICATION OF PSEUDOMONAS AERUGINOSA
Descriptor:Nitric oxide reductase subunit C, Nitric oxide reductase subunit B, Nitrite reductase, ...
Authors:Terasaka, E., Sugimoto, H., Shiro, Y., Tosha, T.
Deposit date:2016-08-31
Release date:2017-08-16
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Dynamics of nitric oxide controlled by protein complex in bacterial system
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5GUX
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CYTOCHROME C-DEPENDENT NITRIC OXIDE REDUCTASE (CNOR) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH XENON
Descriptor:Antibody fab fragment light chain, Antibody fab fragment heavy chain, Nitric oxide reductase subunit B, ...
Authors:Ishii, S., Terasaka, E., Sugimoto, H., Shiro, Y., Tosha, T.
Deposit date:2016-08-31
Release date:2017-08-16
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Dynamics of nitric oxide controlled by protein complex in bacterial system.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3A0R
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CRYSTAL STRUCTURE OF HISTIDINE KINASE THKA (TM1359) IN COMPLEX WITH RESPONSE REGULATOR PROTEIN TRRA (TM1360)
Descriptor:Sensor protein, Response regulator, MERCURY (II) ION
Authors:Yamada, S., Sugimoto, H., Kobayashi, M., Ohno, A., Nakamura, H., Shiro, Y.
Deposit date:2009-03-24
Release date:2009-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure of PAS-linked histidine kinase and the response regulator complex
Structure, 17, 2009
1FIM
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MACROPHAGE MIGRATION INHIBITORY FACTOR
Descriptor:MACROPHAGE MIGRATION INHIBITORY FACTOR
Authors:Suzuki, M., Sugimoto, H., Nakagawa, A., Tanaka, I.
Deposit date:1996-01-31
Release date:1996-07-11
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the macrophage migration inhibitory factor from rat liver.
Nat.Struct.Biol., 3, 1996
3CV8
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CRYSTAL STRUCTURE OF VITAMIN D HYDROXYLASE CYTOCHROME P450 105A1 (R84F MUTANT)
Descriptor:Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Hayashi, K., Sugimoto, H., Shinkyo, R., Yamada, M., Ikeda, S., Ikushiro, S., Kamakura, M., Shiro, Y., Sakaki, T.
Deposit date:2008-04-18
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-based design of a highly active vitamin D hydroxylase from Streptomyces griseolus CYP105A1
Biochemistry, 47, 2008
3CV9
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CRYSTAL STRUCTURE OF VITAMIN D HYDROXYLASE CYTOCHROME P450 105A1 (R73A/R84A MUTANT) IN COMPLEX WITH 1ALPHA,25-DIHYDROXYVITAMIN D3
Descriptor:Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE, 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL
Authors:Hayashi, K., Sugimoto, H., Shinkyo, R., Yamada, M., Ikeda, S., Ikushiro, S., Kamakura, M., Shiro, Y., Sakaki, T.
Deposit date:2008-04-18
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-based design of a highly active vitamin D hydroxylase from Streptomyces griseolus CYP105A1
Biochemistry, 47, 2008
3WFC
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REDUCED AND CARBONMONOXIDE-BOUND CYTOCHROME C-DEPENDENT NITRIC OXIDE REDUCTASE (CNOR) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH ANTIBODY FRAGMENT
Descriptor:antibody fab fragment light chain, antibody fab fragment heavy chain, Nitric oxide reductase subunit B, ...
Authors:Sato, N., Ishii, S., Hino, T., Sugimoto, H., Fukumori, Y., Shiro, Y., Tosha, T.
Deposit date:2013-07-18
Release date:2014-05-28
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of reduced and ligand-bound nitric oxide reductase provide insights into functional differences in respiratory enzymes
Proteins, 2013
3WFD
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REDUCED AND ACETALDOXIME-BOUND CYTOCHROME C-DEPENDENT NITRIC OXIDE REDUCTASE (CNOR) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH ANTIBODY FRAGMENT
Descriptor:antibody fab fragment light chain, antibody fab fragment heavy chain, Nitric oxide reductase subunit B, ...
Authors:Sato, N., Ishii, S., Hino, T., Sugimoto, H., Fukumori, Y., Shiro, Y., Tosha, T.
Deposit date:2013-07-18
Release date:2014-05-28
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of reduced and ligand-bound nitric oxide reductase provide insights into functional differences in respiratory enzymes
Proteins, 2013
3WFE
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REDUCED AND CYANIDE-BOUND CYTOCHROME C-DEPENDENT NITRIC OXIDE REDUCTASE (CNOR) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH ANTIBODY FRAGMENT
Descriptor:antibody fab fragment light chain, antibody fab fragment heavy chain, Nitric oxide reductase subunit B, ...
Authors:Sato, N., Ishii, S., Hino, T., Sugimoto, H., Fukumori, Y., Shiro, Y., Tosha, T.
Deposit date:2013-07-18
Release date:2014-05-28
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structures of reduced and ligand-bound nitric oxide reductase provide insights into functional differences in respiratory enzymes
Proteins, 2013
5Y5F
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STRUCTURE OF CYTOCHROME P450NOR IN NO-BOUND STATE: DAMAGED BY LOW-DOSE (0.72 MGY) X-RAY
Descriptor:NADP nitrous oxide-forming nitric oxide reductase, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE, ...
Authors:Tosha, T., Nomura, T., Nishida, T., Ueno, G., Murakami, H., Yamashita, K., Hirata, K., Yamamoto, M., Ago, H., Sugimoto, H., Shiro, Y., Kubo, M.
Deposit date:2017-08-09
Release date:2017-12-06
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
5Y5G
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STRUCTURE OF CYTOCHROME P450NOR IN NO-BOUND STATE: DAMAGED BY LOW-DOSE (0.72 MGY) X-RAY
Descriptor:NADP nitrous oxide-forming nitric oxide reductase, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE, ...
Authors:Tosha, T., Nomura, T., Nishida, T., Ueno, G., Murakami, H., Yamashita, K., Hirata, K., Yamamoto, M., Ago, H., Sugimoto, H., Shiro, Y., Kubo, M.
Deposit date:2017-08-09
Release date:2017-12-06
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
5Y5H
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SF-ROX STRUCTURE OF CYTOCHROME P450NOR (NO-BOUND STATE) DETERMINED AT SACLA
Descriptor:NADP nitrous oxide-forming nitric oxide reductase, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE, ...
Authors:Tosha, T., Nomura, T., Nishida, T., Yamagiwa, R., Yamashita, K., Hirata, K., Ueno, G., Kimura, T., Hisano, T., Muramoto, K., Sawai, H., Takeda, H., Yamashita, A., Murakami, H., Owada, S., Tono, K., Yabashi, M., Yamamoto, M., Ago, H., Sugimoto, H., Shiro, Y., Kubo, M.
Deposit date:2017-08-09
Release date:2017-12-06
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
5Y5I
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TIME-RESOLVED SFX STRUCTURE OF CYTOCHROME P450NOR: 20 MS AFTER PHOTO-IRRADIATION OF CAGED NO IN THE PRESENCE OF NADH (NO-BOUND STATE), LIGHT DATA
Descriptor:NADP nitrous oxide-forming nitric oxide reductase, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE, ...
Authors:Tosha, T., Nomura, T., Nishida, T., Saeki, N., Okubayashi, K., Yamagiwa, R., Sugahara, M., Nakane, T., Yamashita, K., Hirata, K., Ueno, G., Kimura, T., Hisano, T., Muramoto, K., Sawai, H., Takeda, H., Mizohata, E., Yamashita, A., Kanematsu, Y., Takano, Y., Nango, E., Tanaka, R., Nureki, O., Ikemoto, Y., Murakami, H., Owada, S., Tono, K., Yabashi, M., Yamamoto, M., Ago, H., Iwata, S., Sugimoto, H., Shiro, Y., Kubo, M.
Deposit date:2017-08-09
Release date:2017-12-06
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
5Y5J
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TIME-RESOLVED SFX STRUCTURE OF CYTOCHROME P450NOR: DARK-2 DATA IN THE PRESENCE OF NADH (RESTING STATE)
Descriptor:NADP nitrous oxide-forming nitric oxide reductase, PROTOPORPHYRIN IX CONTAINING FE, GLYCEROL
Authors:Tosha, T., Nomura, T., Nishida, T., Saeki, N., Okubayashi, K., Yamagiwa, R., Sugahara, M., Nakane, T., Yamashita, K., Hirata, K., Ueno, G., Kimura, T., Hisano, T., Muramoto, K., Sawai, H., Takeda, H., Mizohata, E., Yamashita, A., Kanematsu, Y., Takano, Y., Nango, E., Tanaka, R., Nureki, O., Ikemoto, Y., Murakami, H., Owada, S., Tono, K., Yabashi, M., Yamamoto, M., Ago, H., Iwata, S., Sugimoto, H., Shiro, Y., Kubo, M.
Deposit date:2017-08-09
Release date:2017-12-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
5Y5K
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TIME-RESOLVED SFX STRUCTURE OF CYTOCHROME P450NOR : 20 MS AFTER PHOTO-IRRADIATION OF CAGED NO IN THE ABSENCE OF NADH (NO-BOUND STATE), LIGHT DATA
Descriptor:NADP nitrous oxide-forming nitric oxide reductase, PROTOPORPHYRIN IX CONTAINING FE, NITRIC OXIDE
Authors:Tosha, T., Nomura, T., Nishida, T., Saeki, N., Okubayashi, K., Yamagiwa, R., Sugahara, M., Nakane, T., Yamashita, K., Hirata, K., Ueno, G., Kimura, T., Hisano, T., Muramoto, K., Sawai, H., Takeda, H., Mizohata, E., Yamashita, A., Kanematsu, Y., Takano, Y., Nango, E., Tanaka, R., Nureki, O., Ikemoto, Y., Murakami, H., Owada, S., Tono, K., Yabashi, M., Yamamoto, M., Ago, H., Iwata, S., Sugimoto, H., Shiro, Y., Kubo, M.
Deposit date:2017-08-09
Release date:2017-12-06
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017
5Y5L
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TIME-RESOLVED SFX STRUCTURE OF CYTOCHROME P450NOR: DARK-2 DATA IN THE ABSENCE OF NADH (RESTING STATE)
Descriptor:NADP nitrous oxide-forming nitric oxide reductase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Tosha, T., Nomura, T., Nishida, T., Saeki, N., Okubayashi, K., Yamagiwa, R., Sugahara, M., Nakane, T., Yamashita, K., Hirata, K., Ueno, G., Kimura, T., Hisano, T., Muramoto, K., Sawai, H., Takeda, H., Mizohata, E., Yamashita, A., Kanematsu, Y., Takano, Y., Nango, E., Tanaka, R., Nureki, O., Ikemoto, Y., Murakami, H., Owada, S., Tono, K., Yabashi, M., Yamamoto, M., Ago, H., Iwata, S., Sugimoto, H., Shiro, Y., Kubo, M.
Deposit date:2017-08-09
Release date:2017-12-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate.
Nat Commun, 8, 2017