Author results

2MSV
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SOLUTION STRUCTURE OF THE MLKL N-TERMINAL DOMAIN
分子名称:Mixed lineage kinase domain-like protein
著者Su, L., Rizo, J., Quade, B., Wang, H., Sun, L., Wang, X.
登録日2014-08-07
公開日2014-09-24
最終更新日2014-10-29
実験手法SOLUTION NMR
主引用文献A Plug Release Mechanism for Membrane Permeation by MLKL.
Structure, 22, 2014
437D
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CRYSTAL STRUCTURE OF AN RNA PSEUDOKNOT FROM BEET WESTERN YELLOW VIRUS INVOLVED IN RIBOSOMAL FRAMESHIFTING
分子名称:RNA PSEUDOKNOT, MAGNESIUM ION, SODIUM ION
著者Su, L., Chen, L., Egli, M., Berger, J.M., Rich, A.
登録日1998-11-24
公開日1998-12-03
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Minor groove RNA triplex in the crystal structure of a ribosomal frameshifting viral pseudoknot.
Nat.Struct.Biol., 6, 1999
1IMR
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MOLECULAR STRUCTURE OF THE HALOGENATED ANTI-CANCER DRUG IODODOXORUBICIN COMPLEXED WITH D(TGTACA) AND D(CGATCG)
分子名称:DNA (5'-D(*TP*GP*TP*AP*CP*A)-3'), 4'-DEOXY-4'-IODODOXORUBICIN
著者Berger, I., Su, L., Spitzner, J.R., Kang, C., Burke, T.G., Rich, A.
登録日1995-10-23
公開日1996-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular structure of the halogenated anti-cancer drug iododoxorubicin complexed with d(TGTACA) and d(CGATCG).
Nucleic Acids Res., 23, 1995
1IMS
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MOLECULAR STRUCTURE OF THE HALOGENATED ANTI-CANCER DRUG IODODOXORUBICIN COMPLEXED WITH D(TGTACA) AND D(CGATCG)
分子名称:DNA (5'-D(*CP*GP*AP*TP*CP*G)-3'), 4'-DEOXY-4'-IODODOXORUBICIN
著者Berger, I., Su, L., Spitzner, J.R., Kang, C., Burke, T.G., Rich, A.
登録日1995-10-23
公開日1996-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Molecular structure of the halogenated anti-cancer drug iododoxorubicin complexed with d(TGTACA) and d(CGATCG).
Nucleic Acids Res., 23, 1995
1L2X
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ATOMIC RESOLUTION CRYSTAL STRUCTURE OF A VIRAL RNA PSEUDOKNOT
分子名称:RNA pseudoknot, MAGNESIUM ION, SODIUM ION, ...
著者Egli, M., Minasov, G., Su, L., Rich, A.
登録日2002-02-25
公開日2002-03-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Metal ions and flexibility in a viral RNA pseudoknot at atomic resolution.
Proc.Natl.Acad.Sci.USA, 99, 2002
1L3D
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LOW RESOLUTION CRYSTAL STRUCTURE OF A VIRAL RNA PSEUDOKNOT
分子名称:RNA pseudoknot
著者Egli, M., Minasov, G., Su, L., Rich, A.
登録日2002-02-26
公開日2002-03-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Metal ions and flexibility in a viral RNA pseudoknot at atomic resolution.
Proc.Natl.Acad.Sci.USA, 99, 2002
3HF1
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CRYSTAL STRUCTURE OF HUMAN P53R2
分子名称:Ribonucleoside-diphosphate reductase subunit M2 B, FE (III) ION, SULFATE ION
著者Smith, P., Zhou, B., Yuan, Y.-C., Su, L., Tsai, S.-C., Yen, Y.
登録日2009-05-10
公開日2009-10-13
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献2.6 A X-ray crystal structure of human p53R2, a p53-inducible ribonucleotide reductase .
Biochemistry, 48, 2009
3QAZ
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IL-2 MUTANT D10 TERNARY COMPLEX
分子名称:Interleukin-2, Interleukin-2 receptor subunit beta, Cytokine receptor common subunit gamma, ...
著者Levin, A.M., Bates, D.L., Ring, A.M., Lin, J.T., Su, L., Krieg, C., Bowman, G.R., Novick, P., Pande, V.S., Khort, H.E., Boyman, O., Gathman, C.G., Garcia, K.C.
登録日2011-01-12
公開日2012-04-11
最終更新日2014-10-15
実験手法X-RAY DIFFRACTION (3.802 Å)
主引用文献Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'
Nature, 484, 2012
3QB1
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INTERLEUKIN-2 MUTANT D10
分子名称:Interleukin-2
著者Levin, A.M., Bates, D.L., Ring, A.M., Lin, J.T., Su, L., Krieg, C., Bowman, G.R., Novick, P., Pande, V.S., Khort, H.E., Boyman, O., Fathman, C.G., Garcia, K.C.
登録日2011-01-12
公開日2012-04-11
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'
Nature, 484, 2012
5IJB
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THE LIGAND-FREE STRUCTURE OF THE MOUSE TLR4/MD-2 COMPLEX
分子名称:Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ...
著者Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B.
登録日2016-03-01
公開日2016-04-27
最終更新日2016-05-04
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IJC
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THE CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/NEOSEPTIN-3 COMPLEX
分子名称:Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ...
著者Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B.
登録日2016-03-01
公開日2016-04-27
最終更新日2016-05-04
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IJD
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THE CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LIPID A COMPLEX
分子名称:Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ...
著者Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B.
登録日2016-03-01
公開日2016-04-27
最終更新日2016-05-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5VJI
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CRYSTAL STRUCTURE OF THE CLOCK TRANSCRIPTION DOMAIN EXON19 IN COMPLEX WITH A REPRESSOR
分子名称:Circadian locomoter output cycles protein kaput, CLOCK-interacting pacemaker
著者Hou, Z., Su, L., Pei, J., Grishin, N.V., Zhang, H.
登録日2017-04-19
公開日2017-06-07
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal Structure of the CLOCK Transactivation Domain Exon19 in Complex with a Repressor.
Structure, 25, 2017
5VJX
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CRYSTAL STRUCTURE OF THE CLOCK TRANSCRIPTION DOMAIN EXON19 IN COMPLEX WITH A REPRESSOR
分子名称:CLOCK-interacting pacemaker, Circadian locomoter output cycles protein kaput
著者Hou, Z., Su, L., Pei, J., Grishin, N.V., Zhang, H.
登録日2017-04-20
公開日2017-12-06
実験手法X-RAY DIFFRACTION (2.695 Å)
主引用文献Crystal Structure of the CLOCK Transactivation Domain Exon19 in Complex with a Repressor.
Structure, 25, 2017
3LKJ
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SMALL MOLECULE INHIBITION OF THE TNF FAMILY CYOKINE CD40 LIGAND THROUGH A SUBUNIT FRACTURE MECHANISM
分子名称:CD40 ligand, N-ACETYL-D-GLUCOSAMINE, (2R)-{[(2'-[(biphenyl-3-ylmethyl)carbamoyl]-6'-{[(2R)-2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]carbonyl}-6-{[(2R)-2-(1H-pyrrol-1-ylmethyl)pyrrolidin-1-yl]carbonyl}-4,4'-bipyridin-2-yl)carbonyl]amino}(cyclohexyl)ethanoic acid
著者Silvian, L.F., Whitty, A.
登録日2010-01-27
公開日2011-02-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Small Molecule Inhibition of the TNF Family Cytokine CD40 Ligand through a Subunit Fracture Mechanism.
Acs Chem.Biol., 6, 2011
6CT7
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FAB OF ANTI-A-SYNUCLEIN ANTIBODY BIIB054 IN COMPLEX WITH ACETYLATED A-SYNUCLEIN PEPTIDE (1-10)
分子名称:BIIB054 Fab light chain, BIIB054 Fab heavy chain, ACE-MET-ASP-VAL-PHE-MET-LYS-GLY-LEU-SER-LYS, ...
著者Arndt, J.W.
登録日2018-03-22
公開日2018-12-19
最終更新日2018-12-26
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献Development of an aggregate-selective, human-derived alpha-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models.
Neurobiol. Dis., 124, 2018
4G3Y
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CRYSTAL STRUCTURE OF TNF-ALPHA IN COMPLEX WITH INFLIXIMAB FAB FRAGMENT
分子名称:infliximab Fab L, infliximab Fab H, Tumor necrosis factor
著者Liang, S.Y., Dai, J.X., Guo, Y.J., Lou, Z.Y.
登録日2012-07-15
公開日2013-03-27
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for treating tumor necrosis factor alpha (TNFalpha)-associated diseases with the therapeutic antibody infliximab
J.Biol.Chem., 288, 2013
5WQM
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CRYSTAL STRUCTURE OF A CARBONYL REDUCTASE FROM PSEUDOMONAS AERUGINOSA PAO1 (CONDITION I)
分子名称:Probable dehydrogenase, SODIUM ION
著者Li, S., Wang, Y., Bartlam, M.
登録日2016-11-27
公開日2018-07-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and characterization of a NAD(P)H-dependent carbonyl reductase from Pseudomonas aeruginosa PAO1.
FEBS Lett., 591, 2017
5WQN
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CRYSTAL STRUCTURE OF A CARBONYL REDUCTASE FROM PSEUDOMONAS AERUGINOSA PAO1 (CONDITION II)
分子名称:Probable dehydrogenase
著者Li, S., Wang, Y., Bartlam, M.
登録日2016-11-27
公開日2017-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and characterization of a NAD(P)H-dependent carbonyl reductase from Pseudomonas aeruginosa PAO1.
FEBS Lett., 591, 2017
5WQO
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CRYSTAL STRUCTURE OF A CARBONYL REDUCTASE FROM PSEUDOMONAS AERUGINOSA PAO1 IN COMPLEX WITH NADP (CONDITION I)
分子名称:Probable dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 1,2-ETHANEDIOL, ...
著者Li, S., Wang, Y., Bartlam, M.
登録日2016-11-27
公開日2017-10-04
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structure and characterization of a NAD(P)H-dependent carbonyl reductase from Pseudomonas aeruginosa PAO1.
FEBS Lett., 591, 2017
5WQP
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CRYSTAL STRUCTURE OF A CARBONYL REDUCTASE FROM PSEUDOMONAS AERUGINOSA PAO1 IN COMPLEX WITH NADP (CONDITION II)
分子名称:Probable dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NICOTINAMIDE, ...
著者Li, S., Wang, Y., Bartlam, M.
登録日2016-11-27
公開日2017-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and characterization of a NAD(P)H-dependent carbonyl reductase from Pseudomonas aeruginosa PAO1.
FEBS Lett., 591, 2017
6E3K
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INTERFERON GAMMA SIGNALLING COMPLEX WITH IFNGR1 AND IFNGR2
分子名称:Interferon gamma, Interferon gamma receptor 1, Interferon gamma receptor 2, ...
著者Jude, K.M., Mendoza, J.L., Garcia, K.C.
登録日2018-07-14
公開日2019-02-27
最終更新日2019-03-20
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structure of the IFN gamma receptor complex guides design of biased agonists.
Nature, 567, 2019
6E3L
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INTERFERON GAMMA SIGNALLING COMPLEX WITH IFNGR1 AND IFNGR2
分子名称:Interferon gamma, Interferon gamma receptor 1, Interferon gamma receptor 2, ...
著者Jude, K.M., Mendoza, J.L., Garcia, K.C.
登録日2018-07-14
公開日2019-02-27
最終更新日2019-03-20
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structure of the IFN gamma receptor complex guides design of biased agonists.
Nature, 567, 2019
5UE8
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THE CRYSTAL STRUCTURE OF MUNC13-1 C1C2BMUN DOMAIN
分子名称:Protein unc-13 homolog A, ZINC ION, CHLORIDE ION
著者Tomchick, D.R., Rizo, J., Xu, J.
登録日2016-12-29
公開日2017-02-15
最終更新日2018-03-28
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN.
Elife, 6, 2017
5UF7
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CRYSTAL STRUCTURE OF MUNC13-1 MUN DOMAIN
分子名称:Protein unc-13 homolog A
著者Tomchick, D.R., Rizo, J., Xu, J.
登録日2017-01-03
公開日2017-02-15
最終更新日2018-03-28
実験手法X-RAY DIFFRACTION (2.896 Å)
主引用文献Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN.
Elife, 6, 2017