Author results

1DT1
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THERMUS THERMOPHILUS CYTOCHROME C552 SYNTHESIZED BY ESCHERICHIA COLI
Descriptor:CYTOCHROME C552, PROTOPORPHYRIN IX CONTAINING FE
Authors:Fee, J.A., Chen, Y., Hill, M.J., Gomez-Moran, E., Loehr, T., Ai, J., Thony-Meyer, L., Williams, P.A., Stura, E., Sridhar, V., McRee, D.E.
Deposit date:2000-01-10
Release date:2000-02-18
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Integrity of thermus thermophilus cytochrome c552 synthesized by Escherichia coli cells expressing the host-specific cytochrome c maturation genes, ccmABCDEFGH: biochemical, spectral, and structural characterization of the recombinant protein.
Protein Sci., 9, 2000
2AS8
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CRYSTAL STRUCTURE OF MATURE AND FULLY ACTIVE DER P 1 ALLERGEN
Descriptor:Major mite fecal allergen Der p 1, MAGNESIUM ION
Authors:de Halleux, S., Stura, E., VanderElst, L., Carlier, V., Jacquemin, M., Saint-Remy, J.-M.
Deposit date:2005-08-23
Release date:2005-12-06
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Three-dimensional structure and IgE-binding properties of mature fully active Der p 1, a clinically relevant major allergen
J.Allergy Clin.Immunol., 117, 2006
2HEO
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GENERAL STRUCTURE-BASED APPROACH TO THE DESIGN OF PROTEIN LIGANDS: APPLICATION TO THE DESIGN OF KV1.2 POTASSIUM CHANNEL BLOCKERS.
Descriptor:5'-D(*TP*CP*GP*CP*GP*CP*G)-3', Z-DNA binding protein 1
Authors:Magis, C., Gasparini, S., Charbonnier, J.B., Stura, E., Le Du, M.H., Menez, A., Cuniasse, P.
Deposit date:2006-06-21
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-based secondary structure-independent approach to design protein ligands: Application to the design of Kv1.2 potassium channel blockers.
J.Am.Chem.Soc., 128, 2006
2XT1
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CRYSTAL STRUCTURE OF THE HIV-1 CAPSID PROTEIN C-TERMINAL DOMAIN (146- 231) IN COMPLEX WITH A CAMELID VHH.
Descriptor:GAG POLYPROTEIN, CAMELID VHH 9, GLYCEROL
Authors:Igonet, S., Vaney, M.C., Bartonova, V., Helma, J., Rothbauer, U., Leonhardt, H., Stura, E., Krausslich, H.-G., Rey, F.A.
Deposit date:2010-10-03
Release date:2011-10-12
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors
To be Published
2XV6
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CRYSTAL STRUCTURE OF THE HIV-1 CAPSID PROTEIN C-TERMINAL DOMAIN (146- 220) IN COMPLEX WITH A CAMELID VHH.
Descriptor:CAPSID PROTEIN P24, CAMELID VHH 9
Authors:Igonet, S., Vaney, M.C., Bartonova, V., Helma, J., Rothbauer, U., Leonhardt, H., Stura, E., Krausslich, H.-G., Rey, F.A.
Deposit date:2010-10-22
Release date:2011-10-12
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors
To be Published
2XXC
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CRYSTAL STRUCTURE OF A CAMELID VHH RAISED AGAINST THE HIV-1 CAPSID PROTEIN C-TERMINAL DOMAIN.
Descriptor:CAMELID VHH 9
Authors:Igonet, S., Vaney, M.C., Bartonova, V., Helma, J., Rothbauer, U., Leonhardt, H., Stura, E., Krausslich, H.-G., Rey, F.A.
Deposit date:2010-11-10
Release date:2011-10-12
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors
To be Published
2XXM
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CRYSTAL STRUCTURE OF THE HIV-1 CAPSID PROTEIN C-TERMINAL DOMAIN IN COMPLEX WITH A CAMELID VHH AND THE CAI PEPTIDE.
Descriptor:CAPSID PROTEIN P24, CAMELID VHH 9, INHIBITOR OF CAPSID ASSEMBLY, ...
Authors:Igonet, S., Vaney, M.C., Bartonova, V., Helma, J., Rothbauer, U., Leonhardt, H., Stura, E., Krausslich, H.-G., Rey, F.A.
Deposit date:2010-11-10
Release date:2011-10-12
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors
To be Published
1F58
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IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 24-RESIDUE PEPTIDE (RESIDUES 308-333 OF HIV-1 GP120 (MN ISOLATE) WITH ALA TO AIB SUBSTITUTION AT POSITION 323
Descriptor:PROTEIN (IGG1 ANTIBODY 58.2 (LIGHT CHAIN)), PROTEIN (IGG1 ANTIBODY 58.2 (HEAVY CHAIN)), Envelope glycoprotein gp120
Authors:Stanfield, R.L., Cabezas, E., Satterthwait, A.C., Stura, E.A., Profy, A.T., Wilson, I.A.
Deposit date:1998-10-21
Release date:1999-02-02
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs.
Structure Fold.Des., 7, 1999
2F58
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IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 12-RESIDUE CYCLIC PEPTIDE (INCLUDING RESIDUES 315-324 OF HIV-1 GP120) (MN ISOLATE)
Descriptor:PROTEIN (IGG1 FAB 58.2 ANTIBODY (LIGHT CHAIN)), PROTEIN (IGG1 FAB 58.2 ANTIBODY (HEAVY CHAIN)), PROTEIN (HIV-1 GP120), ...
Authors:Stanfield, R.L., Cabezas, E., Satterthwait, A.C., Stura, E.A., Profy, A.T., Wilson, I.A.
Deposit date:1998-10-23
Release date:1999-02-09
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs.
Structure Fold.Des., 7, 1999
3F58
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IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 12-RESIDUE CYCLIC PEPTIDE (INCLUDING RESIDUES 315-324 OF HIV-1 GP120 (MN ISOLATE); H315S MUTATION
Descriptor:PROTEIN (IMMUNOGLOBULIN GAMMA I (58.2)), PROTEIN (CYCLIC PEPTIDE (GP120))
Authors:Stanfield, R.L., Cabezas, E., Satterthwait, A.C., Stura, E.A., Profy, A.T., Wilson, I.A.
Deposit date:1998-10-23
Release date:1999-02-09
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs.
Structure Fold.Des., 7, 1999
2VLW
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CRYSTAL STRUCTURE OF THE MUSCARINIC TOXIN MT7 DIIODOTYR51 DERIVATIVE.
Descriptor:MUSCARINIC M1-TOXIN1, ACETATE ION, SULFATE ION
Authors:Menez, R., Granata, V., Mourier, G., Fruchart-Gaillard, C., Menez, A., Servant, D., Stura, E.A.
Deposit date:2008-01-17
Release date:2008-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Different Interactions between Mt7 Toxin and the Human Muscarinic M1 Receptor in its Free and N-Methylscopolamine-Occupied States.
Mol.Pharmacol., 74, 2008
3LIK
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HUMAN MMP12 IN COMPLEX WITH NON-ZINC CHELATING INHIBITOR
Descriptor:Macrophage metalloelastase, ZINC ION, CALCIUM ION, ...
Authors:Stura, E.A., Dive, V., Devel, L., Czarny, B., Vera, L., Beau, F.
Deposit date:2010-01-25
Release date:2010-09-01
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1' loop canonical conformation.
J.Biol.Chem., 285, 2010
3LIL
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HUMAN MMP12 IN COMPLEX WITH NON-ZINC CHELATING INHIBITOR
Descriptor:Macrophage metalloelastase, ZINC ION, CALCIUM ION, ...
Authors:Stura, E.A., Dive, V., Devel, L., Czarny, B., Vera, L., Beau, F.
Deposit date:2010-01-25
Release date:2010-09-01
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1' loop canonical conformation.
J.Biol.Chem., 285, 2010
3LIR
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HUMAN MMP12 IN COMPLEX WITH NON-ZINC CHELATING INHIBITOR
Descriptor:Macrophage metalloelastase, ZINC ION, CALCIUM ION, ...
Authors:Stura, E.A., Dive, V., Devel, L., Czarny, B., Vera, L., Beau, F.
Deposit date:2010-01-25
Release date:2010-09-01
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1' loop canonical conformation.
J.Biol.Chem., 285, 2010
3LJG
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HUMAN MMP12 IN COMPLEX WITH NON-ZINC CHELATING INHIBITOR
Descriptor:Macrophage metalloelastase, ZINC ION, CALCIUM ION, ...
Authors:Stura, E.A., Dive, V., Devel, L., Vera, L., Beau, F.
Deposit date:2010-01-26
Release date:2010-09-01
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.313 Å)
Cite:Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1' loop canonical conformation.
J.Biol.Chem., 285, 2010
1N64
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CRYSTAL STRUCTURE ANALYSIS OF THE IMMUNODOMINANT ANTIGENIC SITE ON HEPATITIS C VIRUS PROTEIN BOUND TO MAB 19D9D6
Descriptor:Fab 19D9D6 light chain, Fab 19D9D6 heavy chain, Genome polyprotein Capsid protein C
Authors:Menez, R., Bossus, M., Muller, B., Sibai, G., Dalbon, P., Ducancel, F., Jolivet-Reynaud, C., Stura, E.
Deposit date:2002-11-08
Release date:2003-02-25
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structure of a hydrophobic immunodominant antigenic site on hepatitis C virus core protein complexed to monoclonal antibody 19D9D6.
J.Immunol., 170, 2003
1NLB
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CRYSTAL STRUCTURE OF ANTI-HCV MONOCLONAL ANTIBODY 19D9D6
Descriptor:antibody 19D9D6 light chain, antibody 19D9D6 heavy chain
Authors:Menez, R., Bossus, M., Muller, B., Sibai, G., Dalbon, P., Ducancel, F., Jolivet-Reynaud, C., Stura, E.
Deposit date:2003-01-07
Release date:2003-02-25
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of a hydrophobic immunodominant antigenic site on hepatitis C virus core protein complexed to monoclonal antibody 19D9D6.
J.Immunol., 170, 2003
2CKK
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HIGH RESOLUTION CRYSTAL STRUCTURE OF THE HUMAN KIN17 C-TERMINAL DOMAIN CONTAINING A KOW MOTIF
Descriptor:KIN17, IODIDE ION, ACETATE ION
Authors:le Maire, A., Schiltz, M., Pinon-Lataillade, G., Stura, E., Couprie, J., Gondry, M., Angulo-Mora, J., Zinn-Justin, S.
Deposit date:2006-04-20
Release date:2006-10-04
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:A Tandem of SH3-Like Domains Participates in RNA Binding in Kin17, a Human Protein Activated in Response to Genotoxics.
J.Mol.Biol., 364, 2006
2H5F
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DENMOTOXIN: A THE THREE-FINGER TOXIN FROM COLUBRID SNAKE BOIGA DENDROPHILA WITH BIRD-SPECIFIC ACTIVITY
Descriptor:denmotoxin, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Pawlak, J., Kini, R.M., Stura, E.A.
Deposit date:2006-05-26
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Denmotoxin, a three-finger toxin from the colubrid snake Boiga dendrophila (Mangrove Catsnake) with bird-specific activity.
J.Biol.Chem., 281, 2006
2ZCH
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CRYSTAL STRUCTURE OF HUMAN PROSTATE SPECIFIC ANTIGEN COMPLEXED WITH AN ACTIVATING ANTIBODY
Descriptor:Prostate-specific antigen, monoclonal antibody 8G8F5 Fab, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Menez, R., Stura, E., Jolivet-Reynaud, C.
Deposit date:2007-11-08
Release date:2008-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody
J.Mol.Biol., 376, 2008
2ZCK
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX BETWEEN PSA, A SUBSTRAT-ACYL INTERMEDIATE AND AN ACTIVATING ANTIBODY
Descriptor:Prostate-specific antigen, KGISSQY, monoclonal antibody 8G8F5 Fab, ...
Authors:Menez, R., Stura, E., Jolivet-Reynaud, C.
Deposit date:2007-11-09
Release date:2008-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody
J.Mol.Biol., 376, 2008
2ZCL
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CRYSTAL STRUCTURE OF HUMAN PROSTATE SPECIFIC ANTIGEN COMPLEXED WITH AN ACTIVATING ANTIBODY
Descriptor:Prostate-specific antigen, monoclonal antibody 8G8F5 Fab, N-ACETYL-D-GLUCOSAMINE
Authors:Menez, R., Stura, E., Jolivet-Reynaud, C.
Deposit date:2007-11-09
Release date:2008-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody
J.Mol.Biol., 376, 2008
3NDS
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CRYSTAL STRUCTURE OF ENGINEERED NAJA NIGRICOLLIS TOXIN ALPHA
Descriptor:Short neurotoxin 1, (4S)-2-METHYL-2,4-PENTANEDIOL, SULFATE ION
Authors:Stura, E.A., Drevet, P., Gregory, G., Gallopin, M., Vandame, M.
Deposit date:2010-06-08
Release date:2010-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Conformational exchange is critical for the productivity of an oxidative folding intermediate with buried free cysteines.
J.Mol.Biol., 403, 2010
3V95
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CRYSTAL STRUCTURE OF MONOCLONAL HUMAN ANTI-RHESUS D FC AND IGG1 T125(YB2/0) IN THE PRESENCE OF EDTA
Descriptor:Ig gamma-1 chain C region, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Menez, R., A Stura, E., Bourel, D., Siberil, S., Jorieux, S., De Romeuf, C., Ducancel, F., Fridman, W.H., Teillaud, J.L.
Deposit date:2011-12-23
Release date:2012-02-22
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Effect of zinc on human IgG1 and its Fc gamma R interactions.
Immunol.Lett., 143, 2012
6EUO
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CRYSTAL STRUCTURE OF APO FE(II)/ALPHA-KETOGLUTARATE DEPENDENT DIOXYGENASE KDO5
Descriptor:L-lysine 4-hydroxylase, FE (III) ION, D-MALATE, ...
Authors:Isabet, T., Stura, E., Legrand, P., Zaparucha, A., Bastard, K.
Deposit date:2017-10-30
Release date:2018-11-14
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family.
Sci Rep, 8, 2018
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