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2CHN
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BACTEROIDES THETAIOTAOMICRON HEXOSAMINIDASE WITH O-GLCNACASE ACTIVITY- NAG-THIAZOLINE COMPLEX
Descriptor:GLUCOSAMINIDASE, CALCIUM ION, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, ...
Authors:Dennis, R.J., Taylor, E.J., Macauley, M.S., Stubbs, K.A., Turkenburg, J.P., Hart, S.J., Black, G.N., Vocadlo, D.J., Davies, G.J.
Deposit date:2006-03-15
Release date:2006-05-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure and Mechanism of a Bacterial B-Glucosaminidase Having O-Glcnacase Activity
Nat.Struct.Mol.Biol., 13, 2006
2CHO
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BACTEROIDES THETAIOTAOMICRON HEXOSAMINIDASE WITH O-GLCNACASE ACTIVITY
Descriptor:GLUCOSAMINIDASE, CALCIUM ION, ACETATE ION, ...
Authors:Dennis, R.J., Taylor, E.J., Macauley, M.S., Stubbs, K.A., Turkenburg, J.P., Hart, S.J., Black, G.N., Vocadlo, D.J., Davies, G.J.
Deposit date:2006-03-16
Release date:2006-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure and Mechanism of a Bacterial B-Glucosaminidase Having O-Glcnacase Activity
Nat.Struct.Mol.Biol., 13, 2006
2VC9
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FAMILY 89 GLYCOSIDE HYDROLASE FROM CLOSTRIDIUM PERFRINGENS IN COMPLEX WITH 2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN
Descriptor:ALPHA-N-ACETYLGLUCOSAMINIDASE, 2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN, GLYCEROL, ...
Authors:Ficko-Blean, E., Stubbs, K.A., Berg, O., Vocadlo, D.J., Boraston, A.B.
Deposit date:2007-09-19
Release date:2008-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105, 2008
2VCA
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FAMILY 89 GLYCOSIDE HYDROLASE FROM CLOSTRIDIUM PERFRINGENS IN COMPLEX WITH BETA-N-ACETYL-D-GLUCOSAMINE
Descriptor:ALPHA-N-ACETYLGLUCOSAMINIDASE, N-ACETYL-D-GLUCOSAMINE, GLYCEROL, ...
Authors:Ficko-Blean, E., Stubbs, K.A., Berg, O., Vocadlo, D.J., Boraston, A.B.
Deposit date:2007-09-19
Release date:2008-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105, 2008
2VCB
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FAMILY 89 GLYCOSIDE HYDROLASE FROM CLOSTRIDIUM PERFRINGENS IN COMPLEX WITH PUGNAC
Descriptor:ALPHA-N-ACETYLGLUCOSAMINIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE, CALCIUM ION
Authors:Ficko-Blean, E., Stubbs, K.A., Berg, O., Vocadlo, D.J., Boraston, A.B.
Deposit date:2007-09-19
Release date:2008-03-18
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105, 2008
2VCC
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FAMILY 89 GLYCOSIDE HYDROLASE FROM CLOSTRIDIUM PERFRINGENS
Descriptor:ALPHA-N-ACETYLGLUCOSAMINIDASE, GLYCEROL, SULFATE ION, ...
Authors:Ficko-Blean, E., Stubbs, K.A., Berg, O., Vocadlo, D.J., Boraston, A.B.
Deposit date:2007-09-19
Release date:2008-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105, 2008
2X05
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INHIBITION OF THE EXO-BETA-D-GLUCOSAMINIDASE CSXA BY A GLUCOSAMINE- CONFIGURED CASTANOSPERMINE AND AN AMINO-AUSTRALINE ANALOGUE
Descriptor:EXO-BETA-D-GLUCOSAMINIDASE, AMINO-CASTANOSPERMINE, CADMIUM ION
Authors:Pluvinage, B., Ghinet, M.G., Brzezinski, R., Boraston, A.B., Stubbs, K.A.
Deposit date:2009-12-05
Release date:2009-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Inhibition of the Exo-Beta-D-Glucosaminidase Csxa by a Glucosamine-Configured Castanospermine and an Amino-Australine Analogue.
Org.Biomol.Chem., 7, 2009
2X09
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INHIBITION OF THE EXO-BETA-D-GLUCOSAMINIDASE CSXA BY A GLUCOSAMINE- CONFIGURED CASTANOSPERMINE AND AN AMINO-AUSTRALINE ANALOGUE
Descriptor:EXO-BETA-D-GLUCOSAMINIDASE, AMINO-AUSTRALINE, CADMIUM ION
Authors:Pluvinage, B., Ghinet, M.G., Brzezinski, R., Boraston, A.B., Stubbs, K.A.
Deposit date:2009-12-07
Release date:2010-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inhibition of the Exo-Beta-D-Glucosaminidase Csxa by a Glucosamine-Configured Castanospermine and an Amino-Australine Analogue.
Org.Biomol.Chem., 7, 2009
4AZ5
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DIFFERENTIAL INHIBITION OF THE TANDEM GH20 CATALYTIC MODULES IN THE PNEUMOCOCCAL EXO-BETA-D-N-ACETYLGLUCOSAMINIDASE, STRH
Descriptor:BETA-N-ACETYLHEXOSAMINIDASE, (2S,3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-2,3a,5,6,7,7a-hexahydro-1H-pyrano[3,2-d][1,3]thiazole-6,7-diol, MAGNESIUM ION, ...
Authors:Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.
Deposit date:2012-06-22
Release date:2013-07-10
Last modified:2014-12-03
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.
Org.Biomol.Chem., 11, 2013
4AZ6
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DIFFERENTIAL INHIBITION OF THE TANDEM GH20 CATALYTIC MODULES IN THE PNEUMOCOCCAL EXO-BETA-D-N-ACETYLGLUCOSAMINIDASE, STRH
Descriptor:BETA-N-ACETYLHEXOSAMINIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE, 1,2-ETHANEDIOL, ...
Authors:Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.
Deposit date:2012-06-23
Release date:2013-07-10
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.
Org.Biomol.Chem., 11, 2013
4AZ7
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DIFFERENTIAL INHIBITION OF THE TANDEM GH20 CATALYTIC MODULES IN THE PNEUMOCOCCAL EXO-BETA-D-N-ACETYLGLUCOSAMINIDASE, STRH
Descriptor:BETA-N-ACETYLHEXOSAMINIDASE, LOGNAC, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ...
Authors:Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.
Deposit date:2012-06-23
Release date:2013-07-10
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.
Org.Biomol.Chem., 11, 2013
4AZB
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DIFFERENTIAL INHIBITION OF THE TANDEM GH20 CATALYTIC MODULES IN THE PNEUMOCOCCAL EXO-BETA-D-N-ACETYLGLUCOSAMINIDASE, STRH
Descriptor:BETA-N-ACETYLHEXOSAMINIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE, 1,2-ETHANEDIOL, ...
Authors:Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.
Deposit date:2012-06-25
Release date:2013-07-10
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.
Org.Biomol.Chem., 11, 2013
4AZC
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DIFFERENTIAL INHIBITION OF THE TANDEM GH20 CATALYTIC MODULES IN THE PNEUMOCOCCAL EXO-BETA-D-N-ACETYLGLUCOSAMINIDASE, STRH
Descriptor:BETA-N-ACETYLHEXOSAMINIDASE, (2S,3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-2,3a,5,6,7,7a-hexahydro-1H-pyrano[3,2-d][1,3]thiazole-6,7-diol, MAGNESIUM ION, ...
Authors:Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.
Deposit date:2012-06-25
Release date:2013-07-10
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.
Org.Biomol.Chem., 11, 2013
4AZG
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DIFFERENTIAL INHIBITION OF THE TANDEM GH20 CATALYTIC MODULES IN THE PNEUMOCOCCAL EXO-BETA-D-N-ACETYLGLUCOSAMINIDASE, STRH
Descriptor:BETA-N-ACETYLHEXOSAMINIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE, ACETATE ION, ...
Authors:Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.
Deposit date:2012-06-25
Release date:2013-07-10
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.
Org.Biomol.Chem., 11, 2013
4AZH
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DIFFERENTIAL INHIBITION OF THE TANDEM GH20 CATALYTIC MODULES IN THE PNEUMOCOCCAL EXO-BETA-D-N-ACETYLGLUCOSAMINIDASE, STRH
Descriptor:BETA-N-ACETYLHEXOSAMINIDASE, LOGNAC, 1,2-ETHANEDIOL
Authors:Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.
Deposit date:2012-06-26
Release date:2013-07-10
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.
Org.Biomol.Chem., 11, 2013
4AZI
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DIFFERENTIAL INHIBITION OF THE TANDEM GH20 CATALYTIC MODULES IN THE PNEUMOCOCCAL EXO-BETA-D-N-ACETYLGLUCOSAMINIDASE, STRH
Descriptor:BETA-N-ACETYLHEXOSAMINIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE, 1,2-ETHANEDIOL, ...
Authors:Pluvinage, B., Stubbs, K.A., Vocadlo, D.J., Boraston, A.B.
Deposit date:2012-06-26
Release date:2013-07-10
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.
Org.Biomol.Chem., 11, 2013
4BMX
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NATIVE STRUCTURE OF FUTALOSINE HYDROLASE OF HELICOBACTER PYLORI STRAIN 26695
Descriptor:MTA/SAH NUCLEOSIDASE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENINE
Authors:Kim, R.Q., Offen, W.A., Stubbs, K.A., Davies, G.J.
Deposit date:2013-05-12
Release date:2013-09-11
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural Enzymology of Helicobacter Pylori Methylthioadenosine Nucleosidase in the Futalosine Pathway
Acta Crystallogr.,Sect.D, 70, 2014
4BMY
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STRUCTURE OF FUTALOSINE HYDROLASE MUTANT OF HELICOBACTER PYLORI STRAIN 26695
Descriptor:MTA/SAH NUCLEOSIDASE, SULFATE ION
Authors:Kim, R.Q., Offen, W.A., Stubbs, K.A., Davies, G.J.
Deposit date:2013-05-12
Release date:2013-09-11
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Enzymology of Helicobacter Pylori Methylthioadenosine Nucleosidase in the Futalosine Pathway
Acta Crystallogr.,Sect.D, 70, 2014
4BMZ
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STRUCTURE OF FUTALOSINE HYDROLASE MUTANT OF HELICOBACTER PYLORI STRAIN 26695
Descriptor:MTA/SAH NUCLEOSIDASE, 5'-DEOXY-5'-METHYLTHIOADENOSINE
Authors:Kim, R.Q., Offen, W.A., Stubbs, K.A., Davies, G.J.
Deposit date:2013-05-12
Release date:2013-09-11
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural Enzymology of Helicobacter Pylori Methylthioadenosine Nucleosidase in the Futalosine Pathway
Acta Crystallogr.,Sect.D, 70, 2014
4BN0
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STRUCTURE OF FUTALOSINE HYDROLASE MUTANT OF HELICOBACTER PYLORI STRAIN 26695
Descriptor:MTA/SAH NUCLEOSIDASE
Authors:Kim, R.Q., Offen, W.A., Stubbs, K.A., Davies, G.J.
Deposit date:2013-05-12
Release date:2013-09-11
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Structural Enzymology of Helicobacter Pylori Methylthioadenosine Nucleosidase in the Futalosine Pathway
Acta Crystallogr.,Sect.D, 70, 2014
4CU6
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UNRAVELLING THE MULTIPLE FUNCTIONS OF THE ARCHITECTURALLY INTRICATE STREPTOCOCCUS PNEUMONIAE BETA-GALACTOSIDASE, BGAA
Descriptor:BETA-GALACTOSIDASE, 1,2-ETHANEDIOL, SULFATE ION
Authors:Singh, A.K., Pluvinage, B., Higgins, M.A., Dalia, A.B., Flynn, M., Lloyd, A.R., Weiser, J.N., Stubbs, K.A., Boraston, A.B., King, S.J.
Deposit date:2014-03-17
Release date:2014-08-20
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Unravelling the Multiple Functions of the Architecturally Intricate Streptococcus Pneumoniae Beta-Galactosidase, Bgaa.
Plos Pathog., 10, 2014
4CU7
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UNRAVELLING THE MULTIPLE FUNCTIONS OF THE ARCHITECTURALLY INTRICATE STREPTOCOCCUS PNEUMONIAE BETA-GALACTOSIDASE, BGAA
Descriptor:BETA-GALACTOSIDASE, D-galacto-isofagomine, SULFATE ION, ...
Authors:Singh, A.K., Pluvinage, B., Higgins, M.A., Dalia, A.B., Flynn, M., Lloyd, A.R., Weiser, J.N., Stubbs, K.A., Boraston, A.B., King, S.J.
Deposit date:2014-03-17
Release date:2014-08-20
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Unravelling the Multiple Functions of the Architecturally Intricate Streptococcus Pneumoniae Beta-Galactosidase, Bgaa.
Plos Pathog., 10, 2014
4CU8
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UNRAVELLING THE MULTIPLE FUNCTIONS OF THE ARCHITECTURALLY INTRICATE STREPTOCOCCUS PNEUMONIAE BETA-GALACTOSIDASE, BGAA
Descriptor:GLYCOSIDE HYDROLASE 2, (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, ...
Authors:Singh, A.K., Pluvinage, B., Higgins, M.A., Dalia, A.B., Flynn, M., Lloyd, A.R., Weiser, J.N., Stubbs, K.A., Boraston, A.B., King, S.J.
Deposit date:2014-03-17
Release date:2014-08-20
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Unravelling the Multiple Functions of the Architecturally Intricate Streptococcus Pneumoniae Beta-Galactosidase, Bgaa.
Plos Pathog., 10, 2014
4CU9
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UNRAVELLING THE MULTIPLE FUNCTIONS OF THE ARCHITECTURALLY INTRICATE STREPTOCOCCUS PNEUMONIAE BETA-GALACTOSIDASE, BGAA
Descriptor:BETA-GALACTOSIDASE, CALCIUM ION, 1,2-ETHANEDIOL
Authors:Singh, A.K., Pluvinage, B., Higgins, M.A., Dalia, A.B., Flynn, M., Lloyd, A.R., Weiser, J.N., Stubbs, K.A., Boraston, A.B., King, S.J.
Deposit date:2014-03-17
Release date:2014-08-20
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Unravelling the Multiple Functions of the Architecturally Intricate Streptococcus Pneumoniae Beta-Galactosidase, Bgaa.
Plos Pathog., 10, 2014
4CUA
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UNRAVELLING THE MULTIPLE FUNCTIONS OF THE ARCHITECTURALLY INTRICATE STREPTOCOCCUS PNEUMONIAE BETA-GALACTOSIDASE, BGAA
Descriptor:BETA-GALACTOSIDASE, CALCIUM ION, 1,2-ETHANEDIOL
Authors:Singh, A.K., Pluvinage, B., Higgins, M.A., Dalia, A.B., Flynn, M., Lloyd, A.R., Weiser, J.N., Stubbs, K.A., Boraston, A.B., King, S.J.
Deposit date:2014-03-17
Release date:2014-08-20
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Unravelling the Multiple Functions of the Architecturally Intricate Streptococcus Pneumoniae Beta-Galactosidase, Bgaa.
Plos Pathog., 10, 2014