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2XMY
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DISCOVERY AND CHARACTERISATION OF 2-ANILINO-4-(THIAZOL-5-YL) PYRIMIDINE TRANSCRIPTIONAL CDK INHIBITORS AS ANTICANCER AGENTS
Descriptor:CELL DIVISION PROTEIN KINASE 2, 4-[4-(3,4-DIMETHYL-2-OXO-2,3-DIHYDRO-THIAZOL-5-YL)-PYRIMIDIN-2-YLAMINO]-N-(2-METHOXY-ETHYL)-BENZENESULFONAMIDE
Authors:Wang, S., Griffiths, G., Midgley, C.A., Barnett, A.L., Cooper, M., Grabarek, J., Ingram, L., Jackson, W., Kontopidis, G., McClue, S.J., McInnes, C., McLachlan, J., Meades, C., Mezna, M., Stuart, I., Thomas, M.P., Zheleva, D.I., Lane, D.P., Jackson, R.C., Glover, D.M., Blake, D.G., Fischer, P.M.
Deposit date:2010-07-29
Release date:2010-11-10
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery and Characterisation of 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Transcriptional Cdk Inhibitors as Anticancer Agents
Chem.Biol., 17, 2010
2XNB
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DISCOVERY AND CHARACTERISATION OF 2-ANILINO-4-(THIAZOL-5-YL) PYRIMIDINE TRANSCRIPTIONAL CDK INHIBITORS AS ANTICANCER AGENTS
Descriptor:CELL DIVISION PROTEIN KINASE 2, 3,4-DIMETHYL-5-(2-{[(1Z)-4-PIPERAZIN-1-YLCYCLOHEXA-2,4-DIEN-1-YLIDENE]AMINO}PYRIMIDIN-4-YL)-1,3-THIAZOL-2(3H)-ONE
Authors:Wang, S., Griffiths, G., Midgley, C.A., Barnett, A.L., Cooper, M., Grabarek, J., Ingram, L., Jackson, W., Kontopidis, G., McClue, S.J., McInnes, C., McLachlan, J., Meades, C., Mezna, M., Stuart, I., Thomas, M.P., Zheleva, D.I., Lane, D.P., Jackson, R.C., Glover, D.M., Blake, D.G., Fischer, P.M.
Deposit date:2010-08-01
Release date:2010-11-10
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery and Characterisation of 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Transcriptional Cdk Inhibitors as Anticancer Agents
Chem.Biol., 17, 2010
6DDD
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STRUCTURE OF THE 50S RIBOSOMAL SUBUNIT FROM METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS IN COMPLEX WITH THE OXAZOLIDINONE ANTIBIOTIC LZD-5
Descriptor:50S ribosomal protein L19, 50S ribosomal protein L2, 50S ribosomal protein L20, ...
Authors:Belousoff, M.J., Venugopal, H., Bamert, R.S., Lithgow, T.
Deposit date:2018-05-10
Release date:2019-03-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:cryoEM-Guided Development of Antibiotics for Drug-Resistant Bacteria.
ChemMedChem, 14, 2019
6DDG
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STRUCTURE OF THE 50S RIBOSOMAL SUBUNIT FROM METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS IN COMPLEX WITH THE OXAZOLIDINONE ANTIBIOTIC LZD-6
Descriptor:50S ribosomal protein L19, 50S ribosomal protein L2, 50S ribosomal protein L20, ...
Authors:Belousoff, M.J., Venugopal, H., Bamert, R.S., Lithgow, T.
Deposit date:2018-05-10
Release date:2019-03-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:cryoEM-Guided Development of Antibiotics for Drug-Resistant Bacteria.
ChemMedChem, 14, 2019