Author results

1HSB
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DIFFERENT LENGTH PEPTIDES BIND TO HLA-AW68 SIMILARLY AT THEIR ENDS BUT BULGE OUT IN THE MIDDLE
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-AW68.1), BETA 2-MICROGLOBULIN, BOUND PEPTIDE FRAGMENT, ...
Authors:Guo, H.-C., Strominger, J.L., Wiley, D.C.
Deposit date:1993-03-30
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle.
Nature, 360, 1992
1HSA
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THE THREE-DIMENSIONAL STRUCTURE OF HLA-B27 AT 2.1 ANGSTROMS RESOLUTION SUGGESTS A GENERAL MECHANISM FOR TIGHT PEPTIDE BINDING TO MHC
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-B*2705), BETA 2-MICROGLOBULIN, MODEL PEPTIDE SEQUENCE - ARAAAAAAA
Authors:Madden, D.R., Gorga, J.C., Strominger, J.L., Wiley, D.C.
Deposit date:1992-08-11
Release date:1992-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The three-dimensional structure of HLA-B27 at 2.1 A resolution suggests a general mechanism for tight peptide binding to MHC.
Cell(Cambridge,Mass.), 70, 1992
1HLA
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STRUCTURE OF THE HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN, HLA-A2
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A2) (ALPHA CHAIN), BETA 2-MICROGLOBULIN
Authors:Bjorkman, P.J., Saper, M.A., Samraoui, B., Bennett, W.S., Strominger, J.L., Wiley, D.C.
Deposit date:1987-10-15
Release date:1988-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the human class I histocompatibility antigen, HLA-A2.
Nature, 329, 1987
1SEB
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COMPLEX OF THE HUMAN MHC CLASS II GLYCOPROTEIN HLA-DR1 AND THE BACTERIAL SUPERANTIGEN SEB
Descriptor:HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, ENDOGENOUS PEPTIDE MODEL, POLY-ALA, ...
Authors:Jardetzky, T.S., Brown, J.H., Gorga, J.C., Stern, L.J., Urban, R.G., Chi, Y.I., Stauffacher, C., Strominger, J.L., Wiley, D.C.
Deposit date:1995-11-26
Release date:1996-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen.
Nature, 368, 1994
1UVQ
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CRYSTAL STRUCTURE OF HLA-DQ0602 IN COMPLEX WITH A HYPOCRETIN PEPTIDE
Descriptor:HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, OREXIN, GLYCINE, ...
Authors:Siebold, C., Hansen, B.E., Wyer, J.R., Harlos, K., Esnouf, R.E., Svejgaard, A., Bell, J.I., Strominger, J.L., Jones, E.Y., Fugger, L.
Deposit date:2004-01-22
Release date:2004-02-05
Last modified:2015-10-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Hla-Dq0602 that Protects Against Type 1 Diabetes and Confers Strong Susceptibility to Narcolepsy
Proc.Natl.Acad.Sci.USA, 101, 2004
1HHI
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THE ANTIGENIC IDENTITY OF PEPTIDE(SLASH)MHC COMPLEXES: A COMPARISON OF THE CONFORMATION OF FIVE PEPTIDES PRESENTED BY HLA-A2
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A*0201) (ALPHA CHAIN), BETA 2-MICROGLOBULIN, INFLUENZA A MATRIX PROTEIN M1 (RESIDUES 58-66)
Authors:Madden, D.R., Garboczi, D.N., Wiley, D.C.
Deposit date:1993-06-30
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2.
Cell(Cambridge,Mass.), 75, 1993
1TMC
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THE THREE-DIMENSIONAL STRUCTURE OF A CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE MISSING THE ALPHA3 DOMAIN OF THE HEAVY CHAIN
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-AW68), BETA 2-MICROGLOBULIN, DECAMERIC PEPTIDE (EVAPPEYHRK)
Authors:Collins, E.J., Garboczi, D.N., Karpusas, M.N., Wiley, D.C.
Deposit date:1994-12-19
Release date:1995-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The three-dimensional structure of a class I major histocompatibility complex molecule missing the alpha 3 domain of the heavy chain.
Proc.Natl.Acad.Sci.USA, 92, 1995
2HLA
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SPECIFICITY POCKETS FOR THE SIDE CHAINS OF PEPTIDE ANTIGENS IN HLA-AW68
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-Aw68), BETA 2-MICROGLOBULIN
Authors:Garrett, T.P.J., Saper, M.A., Wiley, D.C.
Deposit date:1989-10-05
Release date:1990-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Specificity pockets for the side chains of peptide antigens in HLA-Aw68.
Nature, 342, 1989
1HHG
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THE ANTIGENIC IDENTITY OF PEPTIDE(SLASH)MHC COMPLEXES: A COMPARISON OF THE CONFORMATION OF FIVE PEPTIDES PRESENTED BY HLA-A2
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A*0201) (ALPHA CHAIN), BETA 2-MICROGLOBULIN, HIV-1 GP120 ENVELOPE PROTEIN (RESIDUES 195-207)
Authors:Madden, D.R., Garboczi, D.N., Wiley, D.C.
Deposit date:1993-06-30
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2.
Cell(Cambridge,Mass.), 75, 1993
1HHH
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THE ANTIGENIC IDENTITY OF PEPTIDE(SLASH)MHC COMPLEXES: A COMPARISON OF THE CONFORMATION OF FIVE PEPTIDES PRESENTED BY HLA-A2
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A*0201) (ALPHA CHAIN), BETA 2-MICROGLOBULIN, HEPATITIS B NUCLEOCAPSID PROTEIN (RESIDUES 18-27)
Authors:Madden, D.R., Garboczi, D.N., Wiley, D.C.
Deposit date:1993-06-30
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2.
Cell(Cambridge,Mass.), 75, 1993
1HHJ
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THE ANTIGENIC IDENTITY OF PEPTIDE(SLASH)MHC COMPLEXES: A COMPARISON OF THE CONFORMATION OF FIVE PEPTIDES PRESENTED BY HLA-A2
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A*0201) (ALPHA CHAIN), BETA 2-MICROGLOBULIN, HIV-1 REVERSE TRANSCRIPTASE (RESIDUES 309-317)
Authors:Madden, D.R., Garboczi, D.N., Wiley, D.C.
Deposit date:1993-06-30
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2.
Cell(Cambridge,Mass.), 75, 1993
1HHK
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THE ANTIGENIC IDENTITY OF PEPTIDE(SLASH)MHC COMPLEXES: A COMPARISON OF THE CONFORMATION OF FIVE PEPTIDES PRESENTED BY HLA-A2
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A*0201) (ALPHA CHAIN), BETA 2-MICROGLOBULIN, NONAMERIC PEPTIDE FROM HTLV-1 TAX PROTEIN (RESIDUES 11-19)
Authors:Madden, D.R., Garboczi, D.N., Wiley, D.C.
Deposit date:1993-06-30
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2.
Cell(Cambridge,Mass.), 75, 1993
2CLR
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THREE DIMENSIONAL STRUCTURE OF A PEPTIDE EXTENDING OUT ONE END OF A CLASS I MHC BINDING SITE
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A 0201) (ALPHA CHAIN), BETA 2-MICROGLOBULIN, DECAMERIC PEPTIDE FROM CALRETICULIN
Authors:Collins, E.J., Garboczi, D.N., Wiley, D.C.
Deposit date:1994-08-01
Release date:1995-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of a peptide extending from one end of a class I MHC binding site.
Nature, 371, 1994
3HLA
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HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN A2.1
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A2.1) (ALPHA CHAIN), BETA 2-MICROGLOBULIN
Authors:Saper, M.A., Bjorkman, P.J., Wiley, D.C.
Deposit date:1989-10-06
Release date:1990-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 A resolution.
J.Mol.Biol., 219, 1991
1DLH
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CRYSTAL STRUCTURE OF THE HUMAN CLASS II MHC PROTEIN HLA-DR1 COMPLEXED WITH AN INFLUENZA VIRUS PEPTIDE
Descriptor:CLASS II HISTOCOMPATIBILITY ANTIGEN (HLA-DR1) (ALPHA CHAIN), CLASS II HISTOCOMPATIBILITY ANTIGEN (HLA-DR1) (BETA CHAIN), ENTEROTOXIN TYPE B PRECURSOR, ...
Authors:Stern, L.J.
Deposit date:1994-02-15
Release date:1994-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide.
Nature, 368, 1994
1AQD
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HLA-DR1 (DRA, DRB1 0101) HUMAN CLASS II HISTOCOMPATIBILITY PROTEIN (EXTRACELLULAR DOMAIN) COMPLEXED WITH ENDOGENOUS PEPTIDE
Descriptor:HLA-DR1 CLASS II HISTOCOMPATIBILITY PROTEIN, HLA-A2
Authors:Murthy, V.L., Stern, L.J.
Deposit date:1997-07-28
Release date:1998-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The class II MHC protein HLA-DR1 in complex with an endogenous peptide: implications for the structural basis of the specificity of peptide binding.
Structure, 5, 1997
1ESF
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STAPHYLOCOCCAL ENTEROTOXIN A
Descriptor:STAPHYLOCOCCAL ENTEROTOXIN A, CADMIUM ION
Authors:Schad, E.M., Svensson, L.A.
Deposit date:1995-05-25
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the superantigen staphylococcal enterotoxin type A.
EMBO J., 14, 1995
1JGD
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HLA-B*2709 BOUND TO DECA-PEPTIDE S10R
Descriptor:HUMAN LYMPHOCYTE ANTIGEN HLA-B27, BETA-2-MICROGLOBULIN, peptide s10R, ...
Authors:Hillig, R.C., Huelsmeyer, M., Saenger, W., Volz, A., Uchanska-Ziegler, B., Ziegler, A.
Deposit date:2001-06-25
Release date:2003-07-01
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Thermodynamic and structural analysis of peptide- and allele-dependent properties of two HLA-B27 subtypes exhibiting differential disease association
J.Biol.Chem., 279, 2004
1JGE
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HLA-B*2705 BOUND TO NONA-PEPTIDE M9
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-27 B*2705 ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Hulsmeyer, M., Hillig, R.C., Volz, A., Ruhl, M., Schroder, W., Saenger, W., Ziegler, A., Uchanska-Ziegler, B.
Deposit date:2001-06-25
Release date:2002-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:HLA-B27 subtypes differentially associated with disease exhibit subtle structural alterations
J.Biol.Chem., 277, 2002
1K5N
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HLA-B*2709 BOUND TO NONA-PEPTIDE M9
Descriptor:major histocompatibility complex molecule HLA-B*2709, beta-2-microglobulin, light chain, ...
Authors:Hulsmeyer, M., Hillig, R.C., Volz, A., Ruhl, M., Schroder, W., Saenger, W., Ziegler, A., Uchanska-Ziegler, B.
Deposit date:2001-10-11
Release date:2002-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:HLA-B27 Subtypes Differentially Associated with Disease Exhibit Subtle Structural Alterations
J.Biol.Chem., 277, 2002
1BX2
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CRYSTAL STRUCTURE OF HLA-DR2 (DRA*0101,DRB1*1501) COMPLEXED WITH A PEPTIDE FROM HUMAN MYELIN BASIC PROTEIN
Descriptor:PROTEIN (HLA-DR2), N-ACETYL-D-GLUCOSAMINE
Authors:Smith, K.J., Pyrdol, J., Gauthier, L., Wiley, D.C., Wucherpfennig, K.
Deposit date:1998-10-12
Release date:1998-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein.
J.Exp.Med., 188, 1998
1HD8
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CRYSTAL STRUCTURE OF A DEACYLATION-DEFECTIVE MUTANT OF PENICILLIN-BINDING PROTEIN 5 AT 2.3 A RESOLUTION
Descriptor:PENICILLIN-BINDING PROTEIN 5
Authors:Davies, C., White, S.W., Nicholas, R.A.
Deposit date:2000-11-11
Release date:2001-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of a Deacylation-Defective Mutant of Penicillin-Binding Protein 5 at 2.3-A Resolution
J.Biol.Chem., 276, 2001
1NJ4
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CRYSTAL STRUCTURE OF A DEACYLATION-DEFECTIVE MUTANT OF PENICILLIN-BINDING PROTEIN 5 AT 1.9 A RESOLUTION
Descriptor:Penicillin-binding protein 5
Authors:Nicola, G., Nicholas, R.A., Davies, C.
Deposit date:2002-12-30
Release date:2003-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of wild-type penicillin-binding protein 5 from Escherichia coli: implications for deacylation of the acyl-enzyme complex.
J.Biol.Chem., 278, 2003
1NZU
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WILD-TYPE PENICILLIN-BINDING PROTEIN 5 FROM E. COLI MODIFIED BY BETA-MERCAPTOETHANOL
Descriptor:Penicillin-binding protein 5, BETA-MERCAPTOETHANOL
Authors:Nicola, G., Nicholas, R.A., Davies, C.
Deposit date:2003-02-19
Release date:2004-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A large displacement of the SXN motif of Cys115-modified penicillin-binding protein 5 from Escherichia coli.
Biochem.J., 392, 2005
1OGT
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CRYSTAL STRUCTURE OF HLA-B*2705 COMPLEXED WITH THE VASOACTIVE INTESTINAL PEPTIDE TYPE 1 RECEPTOR (VIPR) PEPTIDE (RESIDUES 400-408)
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, BETA-2-MICROGLOBULIN, VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1, ...
Authors:Hulsmeyer, M., Fiorillo, M.T., Bettosini, F., Sorrentino, R., Saenger, W., Ziegler, A., Uchanska-Ziegler, B.
Deposit date:2003-05-13
Release date:2004-01-29
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Dual, HLA-B27 subtype-dependent conformation of a self-peptide.
J. Exp. Med., 199, 2004