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2C5Z
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BU of 2c5z by Molmil
Structure and CTD binding of the Set2 SRI domain
Descriptor: SET DOMAIN PROTEIN 2
Authors:Vojnic, E, Simon, B, Strahl, B.D, Sattler, M, Cramer, P.
Deposit date:2005-11-03
Release date:2005-11-14
Last modified:2018-05-09
Method:SOLUTION NMR
Cite:Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription.
J. Biol. Chem., 281, 2006
5D7E
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BU of 5d7e by Molmil
Crystal structure of Taf14 YEATS domain in complex with H3K9ac
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, H3K9ac, ...
Authors:Andrews, F.H, Shanle, E.K, Strahl, B.D, Kutateladze, T.G.
Deposit date:2015-08-13
Release date:2015-09-23
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Association of Taf14 with acetylated histone H3 directs gene transcription and the DNA damage response.
Genes Dev., 29, 2015
4BY7
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BU of 4by7 by Molmil
elongating RNA Polymerase II-Bye1 TLD complex
Descriptor: , 5'-D(*DAP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*DTP)-3', 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P.
Deposit date:2013-07-18
Release date:2013-09-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue.
Proc. Natl. Acad. Sci. U.S.A., 110, 2013
4BXZ
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BU of 4bxz by Molmil
RNA Polymerase II-Bye1 complex
Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
Authors:Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P.
Deposit date:2013-07-16
Release date:2013-09-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (4.8 Å)
Cite:Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue
Proc.Natl.Acad.Sci.USA, 110, 2013
4BY1
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BU of 4by1 by Molmil
elongating RNA Polymerase II-Bye1 TLD complex soaked with AMPCPP
Descriptor: 5'-D(*AP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP *TP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*AP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3', ...
Authors:Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P.
Deposit date:2013-07-17
Release date:2013-09-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue
Proc.Natl.Acad.Sci.USA, 110, 2013
4BXX
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BU of 4bxx by Molmil
Arrested RNA polymerase II-Bye1 complex
Descriptor: 5'-D(*AP*GP*CP*TP*AP*GP*CP*TP*TP*AP*CP*CP*TP*GP *GP*TP*GP* BRUP*TP*GP*CP*TP*CP*TP*AP*AP*DC)-3', 5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP)-3', 5'-D(*GP*AP*GP*GP*TP*AP*AP*GP*CP*TP*AP*GP*CP*TP)-3', ...
Authors:Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P.
Deposit date:2013-07-16
Release date:2013-09-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue
Proc.Natl.Acad.Sci.USA, 110, 2013
8DS8
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BU of 8ds8 by Molmil
Crystal structure of human TNRC18 BAH domain in complex with H3K9me3 peptide
Descriptor: Histone H3.1, Trinucleotide repeat-containing gene 18 protein
Authors:Song, J.K, Lu, J.W.
Deposit date:2022-07-21
Release date:2023-08-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons.
Nature, 623, 2023
5IOK
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BU of 5iok by Molmil
Crystal structure of Taf14 YEATS domain in complex with histone H3K9cr
Descriptor: (ACE)QTAR(KCR)ST, DI(HYDROXYETHYL)ETHER, Transcription initiation factor TFIID subunit 14
Authors:Andrews, F.H, Kuateladze, T.G.
Deposit date:2016-03-08
Release date:2016-04-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:The Taf14 YEATS domain is a reader of histone crotonylation.
Nat.Chem.Biol., 12, 2016
4RG2
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BU of 4rg2 by Molmil
Tudor Domain of Tumor suppressor p53BP1 with small molecule ligand
Descriptor: 1,2-ETHANEDIOL, 3-bromo-N-[3-(tert-butylamino)propyl]benzamide, Tumor suppressor p53-binding protein 1, ...
Authors:Dong, A, Mader, P, James, L, Perfetti, M, Tempel, W, Frye, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC)
Deposit date:2014-09-29
Release date:2014-10-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1.
ACS Chem. Biol., 10, 2015
6AXJ
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BU of 6axj by Molmil
Crystal structure of the Yaf9 YEATS domain bound to H3K27ac
Descriptor: ALY-SER-ALA-PRO-ALA, GLYCEROL, Protein AF-9 homolog, ...
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2017-09-06
Release date:2017-11-22
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.379 Å)
Cite:Yaf9 subunit of the NuA4 and SWR1 complexes targets histone H3K27ac through its YEATS domain.
Nucleic Acids Res., 46, 2018
7RGW
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BU of 7rgw by Molmil
Crystal structure of HERC2 DOC domain
Descriptor: DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase HERC2
Authors:Liu, J, Tencer, A.H, Kutateladze, T.G.
Deposit date:2021-07-15
Release date:2022-07-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The ZZ domain of HERC2 is a receptor of arginylated substrates.
Sci Rep, 12, 2022
6VIL
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BU of 6vil by Molmil
Crystal structure of mouse BAHCC1 BAH domain in complex with H3K27me3
Descriptor: BAH and coiled-coil domain-containing protein 1, Histone H3.1
Authors:Song, J, Lu, J.
Deposit date:2020-01-13
Release date:2020-09-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:BAHCC1 binds H3K27me3 via a conserved BAH module to mediate gene silencing and oncogenesis.
Nat.Genet., 52, 2020
8I3G
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BU of 8i3g by Molmil
Crystal structure of Eaf3-Eaf7 complex
Descriptor: Chromatin modification-related protein EAF3, Chromatin modification-related protein EAF7
Authors:Chen, Z, Xu, C.
Deposit date:2023-01-17
Release date:2023-05-31
Last modified:2023-06-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis for Eaf3-mediated assembly of Rpd3S and NuA4.
Cell Discov, 9, 2023
8I3F
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BU of 8i3f by Molmil
Crystal structure of Rco1-Eaf3 with peptide of histone H3 N-terminal
Descriptor: Chromatin modification-related protein EAF3, Histone H3, RCO1 isoform 1, ...
Authors:Chen, Z, Xu, C.
Deposit date:2023-01-17
Release date:2023-05-31
Last modified:2023-06-14
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Molecular basis for Eaf3-mediated assembly of Rpd3S and NuA4.
Cell Discov, 9, 2023
7UHE
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BU of 7uhe by Molmil
Taf14 ET domain in complex with C-terminal tail of Taf2
Descriptor: C-terminal tail of Transcription initiation factor TFIID subunit 2, Transcription initiation factor TFIID subunit 14
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2022-03-26
Release date:2022-08-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Taf2 mediates DNA binding of Taf14.
Nat Commun, 13, 2022
6O7G
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BU of 6o7g by Molmil
Solution structure of MLL4 PHD6 domain in complex with histone H4K16ac peptide
Descriptor: Histone H4, Histone-lysine N-methyltransferase 2D, ZINC ION
Authors:Zhang, Y, Kutateladze, T.G.
Deposit date:2019-03-07
Release date:2019-05-22
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.
Nat Commun, 10, 2019
6OIE
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BU of 6oie by Molmil
The double PHD finger (DPF) of MORF in complex with histone H3K14cr
Descriptor: Histone H3.1t peptide, Histone acetyltransferase KAT6B, ZINC ION
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2019-04-09
Release date:2019-11-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.075 Å)
Cite:Histone H3K23-specific acetylation by MORF is coupled to H3K14 acylation.
Nat Commun, 10, 2019
6PZV
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BU of 6pzv by Molmil
Crystal Structure of Bovine DNMT1 RFTS domain in complex with H3K9me3 and Ubiquitin
Descriptor: CITRATE ANION, DNA (cytosine-5)-methyltransferase 1, Histone H3.3, ...
Authors:Ren, W, Song, J.
Deposit date:2019-08-01
Release date:2020-07-15
Last modified:2020-08-12
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation.
Proc.Natl.Acad.Sci.USA, 117, 2020
4X34
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BU of 4x34 by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K381acK382me2
Descriptor: THR-SER-ARG-HIS-ALY-MLY-LEU-MET-PHE-LYS, Tumor suppressor p53-binding protein 1
Authors:Tong, Q, Kutateladze, T.G.
Deposit date:2014-11-27
Release date:2015-03-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:An Acetyl-Methyl Switch Drives a Conformational Change in p53.
Structure, 23, 2015
4YHZ
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BU of 4yhz by Molmil
Crystal structure of 304M3-B Fab in complex with H3K4me3 peptide
Descriptor: Fab Heavy Chain, Fab Light Chain, GLYCEROL, ...
Authors:Hattori, T, Dementieva, I.S, Montano, S.P, Koide, S.
Deposit date:2015-02-27
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation.
Proc.Natl.Acad.Sci.USA, 113, 2016
4YHY
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BU of 4yhy by Molmil
Crystal structure of 309M3-B in complex with trimethylated Lys
Descriptor: Fab Heavy Chain, Fab Light Chain, N-TRIMETHYLLYSINE
Authors:Hattori, T, Dementieva, I.S, Montano, S.P, Koide, S.
Deposit date:2015-02-27
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation.
Proc.Natl.Acad.Sci.USA, 113, 2016
4YHP
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BU of 4yhp by Molmil
Crystal structure of 309M3-B Fab in complex with H3K9me3 peptide
Descriptor: Fab Heavy Chain, Fab Light Chain, H3K9me3 peptide
Authors:Hattori, T, Dementieva, I.S, Montano, S.P, Koide, S.
Deposit date:2015-02-27
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation.
Proc.Natl.Acad.Sci.USA, 113, 2016
5C6D
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BU of 5c6d by Molmil
Crystal structure of USP7 in complex with UHRF1
Descriptor: E3 ubiquitin-protein ligase UHRF1, Ubiquitin carboxyl-terminal hydrolase 7
Authors:Zhang, Z.-M, Song, J.
Deposit date:2015-06-22
Release date:2015-09-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.292 Å)
Cite:An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1.
Cell Rep, 12, 2015
5DAH
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BU of 5dah by Molmil
Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide
Descriptor: Histone H3 peptide, Protein AF-10, SULFATE ION, ...
Authors:Chen, S, Patel, D.J.
Deposit date:2015-08-19
Release date:2015-10-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.611 Å)
Cite:The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Mol.Cell, 60, 2015
5DAG
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BU of 5dag by Molmil
Crystal structure of PZP domain of human AF10 protein
Descriptor: Protein AF-10, ZINC ION
Authors:Chen, S, Patel, D.J.
Deposit date:2015-08-19
Release date:2015-10-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Mol.Cell, 60, 2015

 

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