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4TN3
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BU of 4tn3 by Molmil
Structure of the BBox-Coiled-coil region of Rhesus Trim5alpha
Descriptor: TRIM5/cyclophilin A fusion protein/T4 Lysozyme chimera, ZINC ION
Authors:Kirkpatrick, J.J, Stoye, J.P, Taylor, I.A, Goldstone, D.C.
Deposit date:2014-06-03
Release date:2014-07-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1989 Å)
Cite:Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice.
Proc.Natl.Acad.Sci.USA, 111, 2014
5AJA
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BU of 5aja by Molmil
Crystal structure of mandrill SAMHD1 (amino acid residues 1-114) bound to Vpx isolated from mandrill and human DCAF1 (amino acid residues 1058-1396)
Descriptor: PROTEIN VPRBP, SAM DOMAIN AND HD DOMAIN-CONTAINING PROTEIN, VPX PROTEIN, ...
Authors:Schwefel, D, Boucherit, V.C, Christodoulou, E, Walker, P.A, Stoye, J.P, Bishop, K.N, Taylor, I.A.
Deposit date:2015-02-20
Release date:2015-04-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.649 Å)
Cite:Molecular Determinants for Recognition of Divergent Samhd1 Proteins by the Lentiviral Accessory Protein Vpx.
Cell Host Microbe., 17, 2015
3BP9
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BU of 3bp9 by Molmil
Structure of B-tropic MLV capsid N-terminal domain
Descriptor: GLYCEROL, Gag protein, ISOPROPYL ALCOHOL
Authors:Gulnahar, M.B, Dodding, M.P, Goldstone, D.C, Haire, L.F, Stoye, J.P, Taylor, I.A.
Deposit date:2007-12-18
Release date:2008-02-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of B-MLV capsid amino-terminal domain reveals key features of viral tropism, gag assembly and core formation
J.Mol.Biol., 376, 2008
4CC9
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BU of 4cc9 by Molmil
Crystal structure of human SAMHD1 (amino acid residues 582-626) bound to Vpx isolated from sooty mangabey and human DCAF1 (amino acid residues 1058-1396)
Descriptor: DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, PROTEIN VPRBP, PROTEIN VPX, ...
Authors:Schwefel, D, Groom, H.C.T, Boucherit, V.C, Christodoulou, E, Walker, P.A, Stoye, J.P, Bishop, K.N, Taylor, I.A.
Deposit date:2013-10-19
Release date:2013-12-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.473 Å)
Cite:Structural Basis of Lentiviral Subversion of a Cellular Protein Degradation Pathway.
Nature, 505, 2014
1U7K
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BU of 1u7k by Molmil
Structure of a hexameric N-terminal domain from murine leukemia virus capsid
Descriptor: Gag polyprotein
Authors:Mortuza, G.B, Haire, L.F, Stevens, A, Smerdon, S.J, Stoye, J.P, Taylor, I.A.
Deposit date:2004-08-04
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:High-resolution structure of a retroviral capsid hexameric amino-terminal domain.
Nature, 431, 2004
2V4X
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BU of 2v4x by Molmil
Crystal Structure of Jaagsiekte Sheep Retrovirus Capsid N-terminal domain
Descriptor: CAPSID PROTEIN P27
Authors:Mortuza, G.B, Goldstone, D.C, Pashley, C, Haire, L.F, Palmarini, M, Taylor, W.R, Stoye, J.P, Taylor, I.A.
Deposit date:2008-09-30
Release date:2008-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of the Capsid Amino-Terminal Domain from the Betaretrovirus, Jaagsiekte Sheep Retrovirus.
J.Mol.Biol., 386, 2009
2XGV
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BU of 2xgv by Molmil
Structure of the N-terminal domain of capsid protein from Rabbit Endogenous Lentivirus (RELIK)
Descriptor: PSIV CAPSID N-TERMINAL DOMAIN
Authors:Goldstone, D.C, Robertson, L.E, Haire, L.F, Stoye, J.P, Taylor, I.A.
Deposit date:2010-06-07
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Functional Analysis of Prehistoric Lentiviruses Uncovers an Ancient Molecular Interface.
Cell Host Microbe, 8, 2010
2XGU
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BU of 2xgu by Molmil
Structure of the N-terminal domain of capsid protein from Rabbit Endogenous Lentivirus (RELIK)
Descriptor: ACETATE ION, RELIK CAPSID N-TERMINAL DOMAIN
Authors:Goldstone, D.C, Taylor, I.A, Robertson, L.E, Haire, L.F, Stoye, J.P.
Deposit date:2010-06-07
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:Structural and Functional Analysis of Prehistoric Lentiviruses Uncovers an Ancient Molecular Interface.
Cell Host Microbe, 8, 2010
2XGY
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BU of 2xgy by Molmil
Complex of Rabbit Endogenous Lentivirus (RELIK)Capsid with Cyclophilin A
Descriptor: GLYCEROL, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A, RELIK CAPSID N-TERMINAL DOMAIN
Authors:Goldstone, D.C, Robertson, L.E, Haire, L.F, Stoye, J.P, Taylor, I.A.
Deposit date:2010-06-08
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Functional Analysis of Prehistoric Lentiviruses Uncovers an Ancient Molecular Interface.
Cell Host Microbe, 8, 2010
2Y4Z
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BU of 2y4z by Molmil
Structure of the amino-terminal capsid restriction escape mutation N- MLV L10W
Descriptor: CAPSID PROTEIN P30, GLYCEROL
Authors:Goldstone, D.C, Holden-Dye, K, Ohkura, S, Stoye, J.P, Taylor, I.A.
Deposit date:2011-01-11
Release date:2011-11-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Novel Escape Mutants Suggest an Extensive Trim5Alpha Binding Site Spanning the Entire Outer Surface of the Murine Leukemia Virus Capsid Protein.
Plos Pathog., 7, 2011
3U1N
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BU of 3u1n by Molmil
Structure of the catalytic core of human SAMHD1
Descriptor: PHOSPHATE ION, SAM domain and HD domain-containing protein 1, ZINC ION
Authors:Goldstone, D.C, Ennis-Adeniran, V, Walker, P.A, Haire, L.F, Webb, M, Taylor, I.A.
Deposit date:2011-09-30
Release date:2011-11-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
Nature, 480, 2011
5W9A
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BU of 5w9a by Molmil
The structure of the Trim5alpha Bbox- coiled coil in complex LC3B
Descriptor: Microtubule-associated proteins 1A/1B light chain 3B, Tripartite motif-containing protein 5, ZINC ION
Authors:Keown, J.R, Goldstone, D.C.
Deposit date:2017-06-22
Release date:2018-10-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:A helical LC3-interacting region mediates the interaction between the retroviral restriction factor Trim5 alpha and mammalian autophagy-related ATG8 proteins.
J. Biol. Chem., 293, 2018
6S7X
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BU of 6s7x by Molmil
dARC1 capsid domain dimer, orthorhombic form at 1.7 Angstrom
Descriptor: Activity-regulated cytoskeleton associated protein 1, CHLORIDE ION, SODIUM ION
Authors:Cottee, M.A, Taylor, I.A.
Deposit date:2019-07-07
Release date:2020-01-15
Last modified:2020-01-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure ofDrosophila melanogasterARC1 reveals a repurposed molecule with characteristics of retroviral Gag.
Sci Adv, 6, 2020
6S7Y
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BU of 6s7y by Molmil
dARC1 capsid domain dimer, hexagonal form at 2.3 Angstrom
Descriptor: Activity-regulated cytoskeleton associated protein 1
Authors:Cottee, M.A, Taylor, I.A.
Deposit date:2019-07-07
Release date:2020-01-15
Last modified:2020-01-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure ofDrosophila melanogasterARC1 reveals a repurposed molecule with characteristics of retroviral Gag.
Sci Adv, 6, 2020
5M1H
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BU of 5m1h by Molmil
Structure of a Spumaretrovirus Gag central domain reveals an ancient retroviral capsid
Descriptor: Gag protein
Authors:Taylor, I.A, Nicastro, G, Ball, N.
Deposit date:2016-10-07
Release date:2016-10-26
Last modified:2016-11-23
Method:SOLUTION NMR
Cite:Structure of a Spumaretrovirus Gag Central Domain Reveals an Ancient Retroviral Capsid.
Plos Pathog., 12, 2016
5M1G
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BU of 5m1g by Molmil
Structure of a Spumaretrovirus Gag central domain reveals an ancient retroviral capsid
Descriptor: Gag protein
Authors:Nicastro, G, Ball, N, Taylor, I.A.
Deposit date:2016-10-07
Release date:2016-10-26
Last modified:2019-10-30
Method:SOLUTION NMR
Cite:Structure of a Spumaretrovirus Gag Central Domain Reveals an Ancient Retroviral Capsid.
Plos Pathog., 12, 2016
4JMR
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BU of 4jmr by Molmil
A unique spumavirus gag N-terminal domain with functional properties of orthoretroviral Matrix and Capsid
Descriptor: Env protein, Gag protein
Authors:Taylor, I.A, Goldstone, D.C, Flower, T.G, Ball, N.J.
Deposit date:2013-03-14
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A Unique Spumavirus Gag N-terminal Domain with Functional Properties of Orthoretroviral Matrix and Capsid.
Plos Pathog., 9, 2013
4JNH
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BU of 4jnh by Molmil
A unique spumavirus gag N-terminal domain with functional properties of orthoretroviral Matrix and Capsid
Descriptor: Gag polyprotein
Authors:Taylor, I.A, Goldstone, D.C, Flower, T.G, Ball, N.J.
Deposit date:2013-03-15
Release date:2013-05-29
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:A Unique Spumavirus Gag N-terminal Domain with Functional Properties of Orthoretroviral Matrix and Capsid.
Plos Pathog., 9, 2013
7NLI
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BU of 7nli by Molmil
S. cerevisiae Ty1 p22 restriction factor, Gag CA-CTD, AUG2 variant
Descriptor: Ty1 Gag p22
Authors:Cottee, M.A, Letham, S.C, Taylor, I.A.
Deposit date:2021-02-22
Release date:2021-10-06
Method:X-RAY DIFFRACTION (3.119 Å)
Cite:Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control.
Nat Commun, 12, 2021
7NLG
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BU of 7nlg by Molmil
S. cerevisiae Ty1 p22 restriction factor, Gag CA-CTD, AUG2 variant A273V mutant
Descriptor: Ty1 Gag p22
Authors:Cottee, M.A, Taylor, I.A.
Deposit date:2021-02-22
Release date:2021-10-06
Method:X-RAY DIFFRACTION (3.528 Å)
Cite:Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control.
Nat Commun, 12, 2021
7NLH
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BU of 7nlh by Molmil
S. cerevisiae Ty1 p22 restriction factor, Gag CA-CTD, AUG1 variant
Descriptor: Ty1 Gag p22
Authors:Cottee, M.A, Taylor, I.A.
Deposit date:2021-02-22
Release date:2021-10-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control.
Nat Commun, 12, 2021
5AO2
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BU of 5ao2 by Molmil
Crystal structure of human SAMHD1 (amino acid residues 115-583) R164A variant bound to dGTP
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION
Authors:Schwefel, D, Taylor, I.A.
Deposit date:2015-09-09
Release date:2015-10-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.966 Å)
Cite:Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction.
Plos Pathog., 11, 2015
5AO0
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BU of 5ao0 by Molmil
Crystal structure of human SAMHD1 (amino acid residues 41-583) bound to ddGTP
Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION, ...
Authors:Schwefel, D, Taylor, I.A.
Deposit date:2015-09-09
Release date:2015-10-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.731 Å)
Cite:Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction.
Plos Pathog., 11, 2015
5AO4
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BU of 5ao4 by Molmil
Crystal structure of in vitro phosphorylated human SAMHD1 (amino acid residues 115-626) bound to GTP
Descriptor: DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION, GUANOSINE-5'-TRIPHOSPHATE
Authors:Arnold, L.H, Schwefel, D, Taylor, I.A.
Deposit date:2015-09-09
Release date:2015-10-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction.
Plos Pathog., 11, 2015
5AO1
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BU of 5ao1 by Molmil
Crystal structure of human SAMHD1 (amino acid residues 115-583) bound to ddGTP
Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION, ...
Authors:Schwefel, D, Taylor, I.A.
Deposit date:2015-09-09
Release date:2015-10-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.545 Å)
Cite:Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction.
Plos Pathog., 11, 2015

 

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