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1EK3
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BU of 1ek3 by Molmil
KAPPA-4 IMMUNOGLOBULIN VL, REC
Descriptor: CALCIUM ION, CHLORIDE ION, KAPPA-4 IMMUNOGLOBULIN LIGHT CHAIN VL
Authors:Pokkuluri, P.R, Huang, D.-B, Raffen, R, Stevens, F.J, Schiffer, M.
Deposit date:2000-03-06
Release date:2001-03-06
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Structure of Amyloidogenic Kappa-4 Immunoglobulin VL, REC
To be Published
1CD0
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BU of 1cd0 by Molmil
STRUCTURE OF HUMAN LAMDA-6 LIGHT CHAIN DIMER JTO
Descriptor: PROTEIN (JTO, A VARIABLE DOMAIN FROM LAMBDA-6 TYPE IMMUNOGLOBULIN LIGHT CHAIN)
Authors:Pokkuluri, P.R, Solomon, A, Weiss, D.T, Stevens, F.J, Schiffer, M.
Deposit date:1999-03-05
Release date:2000-03-06
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Tertiary structure of human lambda 6 light chains.
Amyloid, 6, 1999
2CD0
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BU of 2cd0 by Molmil
STRUCTURE OF HUMAN LAMBDA-6 LIGHT CHAIN DIMER WIL
Descriptor: PROTEIN (BENCE-JONES PROTEIN WIL, A VARIABLE DOMAIN FROM LAMBDA-6 TYPE IMMUNOGLOBULIN LIGHT CHAIN)
Authors:Pokkuluri, P.R, Solomon, A, Weiss, D.T, Stevens, F.J, Schiffer, M.
Deposit date:1999-03-08
Release date:2000-03-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Tertiary structure of human lambda 6 light chains.
Amyloid, 6, 1999
1QAC
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BU of 1qac by Molmil
CHANGE IN DIMERIZATION MODE BY REMOVAL OF A SINGLE UNSATISFIED POLAR RESIDUE
Descriptor: IMMUNOGLOBULIN LIGHT CHAIN VARIABLE DOMAIN
Authors:Pokkuluri, P.R, Cai, X, Johnson, G, Stevens, F.J, Schiffer, M.
Deposit date:1999-02-25
Release date:2000-02-23
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Change in dimerization mode by removal of a single unsatisfied polar residue located at the interface.
Protein Sci., 9, 2000
1EEU
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BU of 1eeu by Molmil
M4L/Y(27D)D/Q89D/T94H mutant of LEN
Descriptor: ISOPROPYL ALCOHOL, KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN)
Authors:Pokkuluri, P.R, Cai, X, Gu, M, Stevens, F.J, Schiffer, M.
Deposit date:2000-02-03
Release date:2001-02-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Factors contributing to decreased protein stability when aspartic acid residues are in beta-sheet regions.
Protein Sci., 11, 2002
1EFQ
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BU of 1efq by Molmil
Q38D mutant of LEN
Descriptor: KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN), URANYL (VI) ION, ZINC ION
Authors:Pokkuluri, P.R, Cai, X, Gu, M, Stevens, F.J, Schiffer, M.
Deposit date:2000-02-09
Release date:2001-02-09
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Factors contributing to decreased protein stability when aspartic acid residues are in beta-sheet regions.
Protein Sci., 11, 2002
1EEQ
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BU of 1eeq by Molmil
M4L/Y(27D)D/T94H Mutant of LEN
Descriptor: KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN)
Authors:Pokkuluri, P.R, Raffen, R, Dieckman, L, Boogaard, C, Stevens, F.J, Schiffer, M.
Deposit date:2000-02-01
Release date:2001-02-01
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Increasing protein stability by polar surface residues: domain-wide consequences of interactions within a loop.
Biophys.J., 82, 2002
5LVE
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BU of 5lve by Molmil
STRUCTURE OF THE VARIABLE DOMAIN OF HUMAN IMMUNOGLOBULIN K-4 LIGHT CHAIN LEN
Descriptor: BENCE-JONES PROTEIN LEN, ZINC ION
Authors:Schiffer, M, Huang, D.-B, Chang, C.-H.
Deposit date:1999-02-24
Release date:2000-02-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Change in dimerization mode by removal of a single unsatisfied polar residue located at the interface.
Protein Sci., 9, 2000
1BJM
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BU of 1bjm by Molmil
LOC NAKS, A LAMBDA 1 TYPE LIGHT-CHAIN DIMER (BENCE-JONES PROTEIN) CRYSTALLIZED IN NAKSO4
Descriptor: LOC - LAMBDA 1 TYPE LIGHT-CHAIN DIMER
Authors:Schiffer, M, Huang, D.B.
Deposit date:1995-05-26
Release date:1995-12-07
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three quaternary structures for a single protein.
Proc.Natl.Acad.Sci.USA, 93, 1996
4LVE
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BU of 4lve by Molmil
LEN K30T MUTANT: A DOMAIN FLIP AS A RESULT OF A SINGLE AMINO ACID SUBSTITUTION
Descriptor: LEN
Authors:Schiffer, M, Pokkuluri, P.R.
Deposit date:1998-05-12
Release date:1999-05-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A domain flip as a result of a single amino-acid substitution.
Structure, 6, 1998
3BJL
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BU of 3bjl by Molmil
LOC, A LAMBDA 1 TYPE LIGHT-CHAIN DIMER (BENCE-JONES PROTEIN) CRYSTALLIZED IN AMMONIUM SULFATE
Descriptor: LOC - LAMBDA 1 TYPE LIGHT-CHAIN DIMER
Authors:Schiffer, M, Huang, D.B.
Deposit date:1995-05-26
Release date:1995-12-07
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Three quaternary structures for a single protein.
Proc.Natl.Acad.Sci.USA, 93, 1996
1LVE
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BU of 1lve by Molmil
STRUCTURE OF THE VARIABLE DOMAIN OF HUMAN IMMUNOGLOBULIN K-4 LIGHT CHAIN LEN
Descriptor: LEN, A VARIABLE DOMAIN FROM KAPPA-4 TYPE
Authors:Schiffer, M, Huang, D.-B, Chang, C.-H.
Deposit date:1996-07-17
Release date:1998-01-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Variable domain structure of kappaIV human light chain Len: high homology to the murine light chain McPC603.
Mol.Immunol., 34, 1997
3LVE
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BU of 3lve by Molmil
LEN Q38E MUTANT: A DOMAIN FLIP FROM A SINGLE AMINO ACID SUBSTITUTION
Descriptor: LEN, ZINC ION
Authors:Schiffer, M, Pokkuluri, P.R.
Deposit date:1998-05-12
Release date:1999-05-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:A domain flip as a result of a single amino-acid substitution.
Structure, 6, 1998
4BJL
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BU of 4bjl by Molmil
LOCW, A LAMBDA 1 TYPE LIGHT-CHAIN DIMER (BENCE-JONES PROTEIN) CRYSTALLIZED IN DISTILLED WATER
Descriptor: LOC - LAMBDA 1 TYPE LIGHT-CHAIN DIMER
Authors:Schiffer, M, Huang, D.B.
Deposit date:1995-05-26
Release date:1995-12-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three quaternary structures for a single protein.
Proc.Natl.Acad.Sci.USA, 93, 1996
1WTL
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BU of 1wtl by Molmil
COMPARISON OF CRYSTAL STRUCTURES OF TWO HOMOLOGOUS PROTEINS: STRUCTURAL ORIGIN OF ALTERED DOMAIN INTERACTIONS IN IMMUNOGLOBULIN LIGHT CHAIN DIMERS
Descriptor: BENCE-JONES PROTEIN MCG (LIGHT CHAIN)
Authors:Huang, D.B, Chang, C.H, Schiffer, M.
Deposit date:1994-06-08
Release date:1994-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Comparison of crystal structures of two homologous proteins: structural origin of altered domain interactions in immunoglobulin light-chain dimers.
Biochemistry, 33, 1994
3UMT
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BU of 3umt by Molmil
scFv12, Anti-BclA antibody single chain variable fragment
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, scFv heavy chain and light chain
Authors:Pokkuluri, P.R.
Deposit date:2011-11-14
Release date:2012-11-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Systematic stability engineering of single-chain antibodies
To be Published
2LVE
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BU of 2lve by Molmil
RECOMBINANT LEN
Descriptor: RLEN
Authors:Schiffer, M, Pokkuluri, P.R.
Deposit date:1998-05-13
Release date:1999-05-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A domain flip as a result of a single amino-acid substitution.
Structure, 6, 1998
1LIL
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BU of 1lil by Molmil
BENCE JONES PROTEIN CLE, A LAMBDA III IMMUNOGLOBULIN LIGHT-CHAIN DIMER
Descriptor: LAMBDA III BENCE JONES PROTEIN CLE
Authors:Schiffer, M, Huang, D.B.
Deposit date:1996-05-13
Release date:1997-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Pitfalls of molecular replacement: the structure determination of an immunoglobulin light-chain dimer.
Acta Crystallogr.,Sect.D, 52, 1996
3MCG
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BU of 3mcg by Molmil
THREE-DIMENSIONAL STRUCTURE OF A LIGHT CHAIN DIMER CRYSTALLIZED IN WATER. CONFORMATIONAL FLEXIBILITY OF A MOLECULE IN TWO CRYSTAL FORMS
Descriptor: IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN)
Authors:Ely, K.R, Herron, J.N, Edmundson, A.B.
Deposit date:1989-05-09
Release date:1990-10-15
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of a light chain dimer crystallized in water. Conformational flexibility of a molecule in two crystal forms.
J.Mol.Biol., 210, 1989
2MCG
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BU of 2mcg by Molmil
THREE-DIMENSIONAL STRUCTURE OF A LIGHT CHAIN DIMER CRYSTALLIZED IN WATER. CONFORMATIONAL FLEXIBILITY OF A MOLECULE IN TWO CRYSTAL FORMS
Descriptor: IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN)
Authors:Ely, K.R, Herron, J.N, Edmundson, A.B.
Deposit date:1989-05-09
Release date:1990-10-15
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of a light chain dimer crystallized in water. Conformational flexibility of a molecule in two crystal forms.
J.Mol.Biol., 210, 1989

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