Author results

1JM6
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PYRUVATE DEHYDROGENASE KINASE, ISOZYME 2, CONTAINING ADP
Descriptor:Pyruvate dehydrogenase kinase, isozyme 2, MAGNESIUM ION, ...
Authors:Steussy, C.N., Popov, K.M., Bowker-Kinley, M.M., Sloan, R.B., Harris, R.A., Hamilton, J.A.
Deposit date:2001-07-17
Release date:2001-10-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of pyruvate dehydrogenase kinase. Novel folding pattern for a serine protein kinase.
J.Biol.Chem., 276, 2001
1X9E
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CRYSTAL STRUCTURE OF HMG-COA SYNTHASE FROM ENTEROCOCCUS FAECALIS
Descriptor:HMG-CoA synthase, SULFATE ION
Authors:Steussy, C.N., Vartia, A.A., Burgner II, J.W., Sutherlin, A., Rodwell, V.W., Stauffacher, C.V.
Deposit date:2004-08-20
Release date:2005-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:X-ray Crystal Structures of HMG-CoA Synthase from Enterococcus faecalis and a Complex with Its Second Substrate/Inhibitor Acetoacetyl-CoA
Biochemistry, 44, 2005
1YSL
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CRYSTAL STRUCTURE OF HMG-COA SYNTHASE FROM ENTEROCOCCUS FAECALIS WITH ACETOACETYL-COA LIGAND.
Descriptor:HMG-CoA synthase, SULFATE ION, GLYCEROL, ...
Authors:Steussy, C.N., Vartia, A.A., Burgner II, J.W., Sutherlin, A., Rodwell, V.W., Stauffacher, C.V.
Deposit date:2005-02-08
Release date:2005-11-08
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray Crystal Structures of HMG-CoA Synthase from Enterococcus faecalis and a Complex with Its Second Substrate/Inhibitor Acetoacetyl-CoA.
Biochemistry, 44, 2005
2HDB
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HMG-COA SYNTHASE FROM ENTEROCOCCUS FAECALIS. MUTATION ALANINE 110 TO GLYCINE
Descriptor:HMG-CoA synthase, SULFATE ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Steussy, C.N., Sutherlin, A., Stauffacher, C.V.
Deposit date:2006-06-20
Release date:2007-03-20
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A structural limitation on enzyme activity: the case of HMG-CoA synthase.
Biochemistry, 45, 2006
4I56
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HMG-COA REDUCTASE FROM PSEUDOMONAS MEVALONII COMPLEXED WITH DITHIO-HMG-COA
Descriptor:3-hydroxy-3-methylglutaryl-coenzyme A reductase, (3S,5S,9R,21S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,21-tetrahydroxy-8,8,21-trimethyl-10,14-dioxo-19-thioxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide, SULFATE ION, ...
Authors:Steussy, C.N., Stauffacher, C.V., Schmidt, T., Crichelow, C.J., Rodwell, V.W., Wrensford, L.V., Min, J., Burgner II, J.W.
Deposit date:2012-11-28
Release date:2013-07-17
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
Biochemistry, 52, 2013
4I64
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3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE FROM PSEUDOMONAS MEVALONII, A HIGH RESOLUTION NATIVE STRUCTURE
Descriptor:3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION
Authors:Steussy, C.N., Stauffacher, C.V., Schmidt, T., Burgner II, J.W., Rodwell, V.W., Wrensford, L.V., Critchelow, C.J., Min, J.
Deposit date:2012-11-29
Release date:2013-07-17
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
Biochemistry, 52, 2013
4I6A
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3-HYDROXY-3-METHYLGLUTARYL (HMG) COENZYME A REDUCTASE FROM PSEUDOMONAS MEVALONII COMPLEXED WITH HMG-COA
Descriptor:3-hydroxy-3-methylglutaryl-coenzyme A reductase, 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, SULFATE ION
Authors:Steussy, C.N., Stauffacher, C.V., Schmidt, T., Burgner II, J.W., Rodwell, V.W., Wrensford, L.V., Critchelow, C.J., Min, J.
Deposit date:2012-11-29
Release date:2013-07-17
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
Biochemistry, 52, 2013
4I6W
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3-HYDROXY-3-METHYLGLUTARYL (HMG) COENZYME-A REDUCTASE COMPLEXED WITH THIOMEVALONATE
Descriptor:3-hydroxy-3-methylglutaryl-coenzyme A reductase, (3S)-3-hydroxy-3-methyl-5-sulfanylpentanoic acid, SULFATE ION, ...
Authors:Steussy, C.N., Stauffacher, C.V., Schmidt, T., Burgner II, J.W., Rodwell, V.W., Wrensford, L.V., Critchelow, C.J., Min, J.
Deposit date:2012-11-30
Release date:2013-07-17
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
Biochemistry, 52, 2013
4I6Y
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3-HYDROXY-3-METHYL (HMG) COENZYME A REDUCTASE BOUND TO R-MEVALONATE
Descriptor:3-hydroxy-3-methylglutaryl-coenzyme A reductase, (R)-MEVALONATE, GLYCEROL, ...
Authors:Steussy, C.N., Stauffacher, C.V., Schmidt, T., Burgner II, J.W., Rodwell, V.W., Wrensford, L.V., Critchelow, C.J., Min, J.
Deposit date:2012-11-30
Release date:2013-07-17
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
Biochemistry, 52, 2013
4I4B
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HMG-COA REDUCTASE FROM PSEUDOMONAS MEVALONII COMPLEXED WITH NAD AND INTERMEDIATE HEMIACETAL FORM OF HMG-COA
Descriptor:3-hydroxy-3-methylglutaryl-coenzyme A reductase, (3R,5R,9R,19R,21S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,21-tetrahydroxy-8,8,21-trimethyl-10,14-dioxo-19-sulfanyl-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide, GLYCEROL, ...
Authors:Stauffacher, C.V., Steussy, C.N., Critchelow, C.J., Schmidt, T., Min, J., Wrensford, L.V., Burgner, J.W., Rodwell, V.W.
Deposit date:2012-11-27
Release date:2013-07-17
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
Biochemistry, 52, 2013
1R31
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HMG-COA REDUCTASE FROM PSEUDOMONAS MEVALONII COMPLEXED WITH HMG-COA
Descriptor:3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION, COENZYME A, ...
Authors:Watson, J.M., Steussy, C.N., Burgner, J.W., Lawrence, C.M., Tabernero, L., Rodwell, V.W., Stauffacher, C.V.
Deposit date:2003-09-30
Release date:2003-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Investigations of the Basis for Stereoselectivity from the Binary Complex of HMG-CoA Reductase.
To be Published
1R7I
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HMG-COA REDUCTASE FROM P. MEVALONII, NATIVE STRUCTURE AT 2.2 ANGSTROMS RESOLUTION.
Descriptor:3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION, GLYCEROL
Authors:Watson, J.M., Steussy, C.N., Burgner, J.W., Lawrence, C.M., Tabernero, L., Rodwell, V.W., Stauffacher, C.V.
Deposit date:2003-10-21
Release date:2003-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural Investigations of the Basis for Stereoselectivity from the Binary Complex of HMG-COA Reductase.
To be Published
2PNR
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CRYSTAL STRUCTURE OF THE ASYMMETRIC PDK3-L2 COMPLEX
Descriptor:[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, DIHYDROLIPOIC ACID
Authors:Vassylyev, D.G., Steussy, C.N., Devedjiev, Y.
Deposit date:2007-04-25
Release date:2007-08-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of an Asymmetric complex of Pyruvate Dehydrogenase Kinase 3 with Lipoyl domain 2 and its Biological Implications
J.Mol.Biol., 370, 2007
5JNP
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CRYSTAL STRUCTURE OF A RICE (ORYZA SATIVA) CELLULOSE SYNTHASE PLANT CONSERVED REGION (P-CR)
Descriptor:Probable cellulose synthase A catalytic subunit 8 [UDP-forming], CITRATE ANION, GLYCEROL, ...
Authors:Rushton, P.S., Olek, A.T., Makowski, L., Badger, J., Steussy, C.N., Carpita, N.C., Stauffacher, C.V.
Deposit date:2016-04-30
Release date:2016-12-28
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:Rice Cellulose SynthaseA8 Plant-Conserved Region Is a Coiled-Coil at the Catalytic Core Entrance.
Plant Physiol., 173, 2017
5V2L
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MEVALONATE DIPHOSPHATE MEDIATED ATP BINDING MECHANISM OF THE MEVALONATE DIPHOSPHATE DECARBOXYLASE FROM ENTEROCOCCUS FAECALIS
Descriptor:Mevalonate diphosphate decarboxylase, ADENOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION
Authors:Stauffacher, C.V., Chen, C.-L.
Deposit date:2017-03-05
Release date:2017-10-18
Last modified:2018-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis.
J. Biol. Chem., 292, 2017
5V2M
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MEVALONATE DIPHOSPHATE MEDIATED ATP BINDING MECHANISM OF THE MEVALONATE DIPHOSPHATE DECARBOXYLASE FROM ENTEROCOCCUS FAECALIS
Descriptor:Mevalonate diphosphate decarboxylase, SULFATE ION
Authors:Stauffacher, C.V., Chen, C.-L.
Deposit date:2017-03-05
Release date:2017-10-18
Last modified:2018-01-10
Method:X-RAY DIFFRACTION (1.989 Å)
Cite:Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis.
J. Biol. Chem., 292, 2017