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4AKJ
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BU of 4akj by Molmil
Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin
Descriptor: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
Authors:Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I.
Deposit date:2012-02-23
Release date:2013-01-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
4AJZ
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BU of 4ajz by Molmil
Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin
Descriptor: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
Authors:Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I.
Deposit date:2012-02-21
Release date:2013-01-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
4AK0
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BU of 4ak0 by Molmil
Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin
Descriptor: INSULIN A CHAIN, INSULIN B CHAIN
Authors:Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I.
Deposit date:2012-02-21
Release date:2013-01-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
4AJX
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BU of 4ajx by Molmil
Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin
Descriptor: IMIDAZOLE, INSULIN, N-(16-Carboxyhexadecanoyl)-L-glutamic acid, ...
Authors:Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I.
Deposit date:2012-02-20
Release date:2013-01-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
4APD
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BU of 4apd by Molmil
Liraglutide
Descriptor: LIRAGLUTIDE, N-hexadecanoyl-L-glutamic acid
Authors:Ludvigsen, S, Steensgaard, D.B, Thomsen, J.K, Strauss, H, Normann, M.
Deposit date:2012-04-02
Release date:2013-07-10
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Liraglutide
To be Published
2W44
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BU of 2w44 by Molmil
Structure DeltaA1-A4 insulin
Descriptor: CHLORIDE ION, INSULIN, RESORCINOL, ...
Authors:Thorsoee, K.S, Schlein, M, Brandt, J, Schluckebier, G, Naver, H.
Deposit date:2008-11-21
Release date:2009-12-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Kinetic Evidence for the Sequential Association of Insulin Binding Sites 1 and 2 to the Insulin Receptor and the Influence of Receptor Isoform.
Biochemistry, 49, 2010
4ZGM
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BU of 4zgm by Molmil
Crystal structure of Semaglutide peptide backbone in complex with the GLP-1 receptor extracellular domain
Descriptor: 3,6,9,12,15,18-hexaoxahexacosan-1-ol, Glucagon-like peptide 1 receptor, Semaglutide peptide backbone; 8Aib,34R-GLP-1(7-37)-OH
Authors:Reedtz-Runge, S.
Deposit date:2015-04-23
Release date:2015-09-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide.
J.Med.Chem., 58, 2015
5BTS
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BU of 5bts by Molmil
Structural and biophysical characterization of a covalent insulin dimer formed during storage of neutral formulation of human insulin
Descriptor: Insulin A chain, Insulin B chain
Authors:Norrman, M, Hjorth, C.F.
Deposit date:2015-06-03
Release date:2016-03-09
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin.
J.Pharm.Sci., 105, 2016
4EFX
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BU of 4efx by Molmil
Highly biologically active insulin with additional disulfide bond
Descriptor: Insulin, ZINC ION
Authors:Norrman, M, Vinther, T.N.
Deposit date:2012-03-30
Release date:2013-03-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Insulin analog with additional disulfide bond has increased stability and preserved activity.
Protein Sci., 22, 2013
6S4J
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BU of 6s4j by Molmil
Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB27, desB30 human insulin
Descriptor: IMIDAZOLE, Insulin, KUT [2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]
Authors:Johansson, E.
Deposit date:2019-06-28
Release date:2020-07-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular engineering of safe and efficacious oral basal insulin.
Nat Commun, 11, 2020
6S4I
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BU of 6s4i by Molmil
Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB30 human insulin
Descriptor: Insulin, NITRATE ION
Authors:Johansson, E.
Deposit date:2019-06-28
Release date:2020-07-15
Last modified:2020-08-12
Method:X-RAY DIFFRACTION (1.511 Å)
Cite:Molecular engineering of safe and efficacious oral basal insulin.
Nat Commun, 11, 2020
6S34
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BU of 6s34 by Molmil
Zinc free, dimeric human insulin determined to 1.35 Angstrom resolution
Descriptor: 1,2-ETHANEDIOL, Insulin A chain, Insulin B chain
Authors:Johansson, E.
Deposit date:2019-06-24
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Zinc free, dimeric human insulin determined to 1.35 Angstrom resolution
Not Published

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