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4V7L
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BU of 4v7l by Molmil
The structures of viomycin bound to the 70S ribosome.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Stanley, R.E, Blaha, G.
Deposit date:2009-11-12
Release date:2014-07-09
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome.
Nat.Struct.Mol.Biol., 17, 2010
4V7M
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BU of 4v7m by Molmil
The structures of Capreomycin bound to the 70S ribosome.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Stanley, R.E, Blaha, G.
Deposit date:2009-11-12
Release date:2014-07-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome.
Nat.Struct.Mol.Biol., 17, 2010
7UXA
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BU of 7uxa by Molmil
Human tRNA Splicing Endonuclease Complex bound to pre-tRNA-ARG
Descriptor: MAGNESIUM ION, RNA (78-MER), tRNA-splicing endonuclease subunit Sen15, ...
Authors:Stanley, R.E, Hayne, C.K.
Deposit date:2022-05-05
Release date:2023-02-08
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex.
Nat.Struct.Mol.Biol., 30, 2023
4V6A
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BU of 4v6a by Molmil
Structure of EF-P bound to the 70S ribosome.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Stanley, R.E, Blaha, G.
Deposit date:2009-06-15
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Formation of the first peptide bond: the structure of EF-P bound to the 70S ribosome.
Science, 325, 2009
4HPQ
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BU of 4hpq by Molmil
Crystal Structure of the Atg17-Atg31-Atg29 Complex
Descriptor: Atg17, Atg29, Atg31
Authors:Stanley, R.E, Ragusa, M.J, Hurley, J.H.
Deposit date:2012-10-24
Release date:2012-12-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:Architecture of the atg17 complex as a scaffold for autophagosome biogenesis.
Cell(Cambridge,Mass.), 151, 2012
7UWF
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BU of 7uwf by Molmil
Human Rix1 sub-complex scaffold
Descriptor: Modulator of non-genomic activity of estrogen receptor, WD repeat-containing protein 18
Authors:Gordon, J, Stanley, R.E.
Deposit date:2022-05-03
Release date:2022-11-02
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM reveals the architecture of the PELP1-WDR18 molecular scaffold.
Nat Commun, 13, 2022
7TJ2
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BU of 7tj2 by Molmil
SARS-CoV-2 endoribonuclease Nsp15 bound to dsRNA
Descriptor: RNA (31-MER), Uridylate-specific endoribonuclease nsp15
Authors:Frazier, M.N, Krahn, J.M, Butay, K.J, Dillard, L.B, Borgnia, M.J, Stanley, R.E.
Deposit date:2022-01-14
Release date:2022-03-23
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Flipped over U: structural basis for dsRNA cleavage by the SARS-CoV-2 endoribonuclease.
Nucleic Acids Res., 50, 2022
7TQV
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BU of 7tqv by Molmil
SARS-CoV-2 endoribonuclease Nsp15 bound to dsRNA
Descriptor: RNA (33-MER), Uridylate-specific endoribonuclease
Authors:Frazier, M.N, Krahn, J.M, Butay, K.J, Dillard, L.B, Borgnia, M.J, Stanley, R.E.
Deposit date:2022-01-27
Release date:2022-03-23
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Flipped over U: structural basis for dsRNA cleavage by the SARS-CoV-2 endoribonuclease.
Nucleic Acids Res., 50, 2022
6OF4
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BU of 6of4 by Molmil
Precursor ribosomal RNA processing complex, apo-state.
Descriptor: CLP1_P domain-containing protein, Ribonuclease
Authors:Pillon, M.C, Hsu, A.L, Krahn, J.M, Williams, J.G, Goslen, K.H, Sobhany, M, Borgnia, M.J, Stanley, R.E.
Deposit date:2019-03-28
Release date:2019-09-11
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex.
Nat.Struct.Mol.Biol., 26, 2019
7SWL
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BU of 7swl by Molmil
CryoEM structure of the N-terminal-deleted Rix7 AAA-ATPase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kocaman, S, Stanley, R.E, Lo, Y.H, Krahn, J, Dandey, V.P, Sobhany, M, Petrovich, M, Williams, J.G, Deterding, L.J, Borgnia, M.J, Etigunta, S.
Deposit date:2021-11-20
Release date:2022-03-02
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly.
Pnas Nexus, 1, 2022
7T3I
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BU of 7t3i by Molmil
CryoEM structure of the Rix7 D2 Walker B mutant
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, Rix7, ...
Authors:Kocaman, S, Stanley, R.E.
Deposit date:2021-12-08
Release date:2022-03-02
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly.
Pnas Nexus, 1, 2022
7T0V
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BU of 7t0v by Molmil
CryoEM structure of the crosslinked Rix7 AAA-ATPase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kocaman, S, Stanley, R.E, Lo, Y.H, Krahn, J, Dandey, V.P, Sobhany, M, Petrovich, M, Williams, J.G, Deterding, L.J, Borgnia, M.J, Etigunta, S.
Deposit date:2021-11-30
Release date:2022-03-02
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly.
Pnas Nexus, 1, 2022
6MAT
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BU of 6mat by Molmil
Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Rix7 mutant, unknown protein
Authors:Lo, Y.H, Sobhany, M, Hsu, A.L, Ford, B.L, Krahn, J.M, Borgnia, M.J, Stanley, R.E.
Deposit date:2018-08-28
Release date:2019-02-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7.
Nat Commun, 10, 2019
6OF2
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BU of 6of2 by Molmil
Precursor ribosomal RNA processing complex, State 2.
Descriptor: CLP1_P domain-containing protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Pillon, M.C, Hsu, A.L, Krahn, J.M, Williams, J.G, Goslen, K.H, Sobhany, M, Borgnia, M.J, Stanley, R.E.
Deposit date:2019-03-28
Release date:2019-09-11
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex.
Nat.Struct.Mol.Biol., 26, 2019
6OF3
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BU of 6of3 by Molmil
Precursor ribosomal RNA processing complex, State 1.
Descriptor: CLP1_P domain-containing protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Pillon, M.C, Hsu, A.L, Krahn, J.M, Williams, J.G, Goslen, K.H, Sobhany, M, Borgnia, M.J, Stanley, R.E.
Deposit date:2019-03-28
Release date:2019-09-11
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex.
Nat.Struct.Mol.Biol., 26, 2019
7N06
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BU of 7n06 by Molmil
SARS-CoV-2 Nsp15 endoribonuclease post-cleavage state
Descriptor: RNA (5'-R(*AP*UP*A)-3'), Uridylate-specific endoribonuclease
Authors:Frazier, M.N, Dillard, L.B, Krahn, J.M, Stanley, R.E.
Deposit date:2021-05-25
Release date:2021-06-02
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U.
Nucleic Acids Res., 49, 2021
7N33
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BU of 7n33 by Molmil
SARS-CoV-2 Nsp15 endoribonuclease pre-cleavage state
Descriptor: RNA (5'-R(*A)-D(*(UFT))-R(P*A)-3'), Uridylate-specific endoribonuclease
Authors:Frazier, M.N, Dillard, L.B, Krahn, J.M, Stanley, R.E.
Deposit date:2021-05-31
Release date:2021-06-09
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U.
Nucleic Acids Res., 49, 2021
5DTC
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BU of 5dtc by Molmil
UBL Structure
Descriptor: Ribosome biogenesis protein YTM1
Authors:Romes, E.M, Stanley, R.E.
Deposit date:2015-09-17
Release date:2015-12-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Crystal Structure of the Ubiquitin-like Domain of Ribosome Assembly Factor Ytm1 and Characterization of Its Interaction with the AAA-ATPase Midasin.
J.Biol.Chem., 291, 2016
7K0R
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BU of 7k0r by Molmil
Nucleotide bound SARS-CoV-2 Nsp15
Descriptor: PHOSPHATE ION, URIDINE-5'-MONOPHOSPHATE, Uridylate-specific endoribonuclease
Authors:Pillon, M.C, Stanley, R.E.
Deposit date:2020-09-04
Release date:2020-12-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics.
Nat Commun, 12, 2021
5SUI
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BU of 5sui by Molmil
Ribosome assembly factor NSA1: C-terminal truncation
Descriptor: Ribosome biogenesis protein NSA1
Authors:Lo, Y.H, Stanley, R.E.
Deposit date:2016-08-03
Release date:2017-04-26
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Ribosome assembly factor
To Be Published
5SUM
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BU of 5sum by Molmil
Ribosome assembly factor NSA1
Descriptor: Ribosome biogenesis protein NSA1
Authors:Lo, Y.H, Stanley, R.E.
Deposit date:2016-08-03
Release date:2017-04-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ribosome assembly factor
To Be Published
4J2G
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BU of 4j2g by Molmil
Atg13 HORMA domain
Descriptor: KLTH0A00704p, SULFATE ION
Authors:Jao, C, Stanley, R.E, Ragusa, M.J, Hurley, J.H.
Deposit date:2013-02-04
Release date:2013-03-20
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:A HORMA domain in Atg13 mediates PI 3-kinase recruitment in autophagy.
Proc.Natl.Acad.Sci.USA, 110, 2013

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