Author results

3ZFI
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RAP1A PROTEIN (SMA2260) FROM SERRATIA MARCESCENS
Descriptor:RAP1A PROTEIN
Authors:Srikannathasan, V., O'Rourke, P.E.F., Rao, V.A., English, G., Coulthurst, S.J., Hunter, W.N.
Deposit date:2012-12-11
Release date:2013-06-19
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural Basis for Type Vi Secreted Peptidoglycan Dl-Endopeptidase Function, Specificity and Neutralization in Serratia Marcescens
Acta Crystallogr.,Sect.D, 69, 2013
3ZIB
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RAP2A PROTEIN (SMA2265) FROM SERRATIA MARCESCENS
Descriptor:RAP2A SMA2265
Authors:Srikannathasan, V., O'Rourke, P.E.F., Rao, V.A., English, G., Coulthurst, S.J., Hunter, W.N.
Deposit date:2013-01-08
Release date:2013-06-19
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for Type Vi Secreted Peptidoglycan Dl-Endopeptidase Function, Specificity and Neutralization in Serratia Marcescens
Acta Crystallogr.,Sect.D, 69, 2013
4BI3
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STRUCTURE AND FUNCTION OF AMIDASE TOXIN - ANTITOXIN COMBINATIONS ASSOCIATED WITH THE TYPE VI SECRETION SYSTEM OF SERRATIA MARCESCENS.
Descriptor:SSP1, SULFATE ION, POTASSIUM ION
Authors:Srikannathasan, V., English, G., Bui, N.K., Trunk, K., Rourke, P.E.F.O., Rao, V.A., Vollmer, W., Coulthurst, S.J., Hunter, W.N.
Deposit date:2013-04-09
Release date:2013-06-19
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Basis for Type Vi Secreted Peptidoglycan Dl-Endopeptidase Function, Specificity and Neutralization in Serratia Marcescens
Acta Crystallogr.,Sect.D, 69, 2013
4BI4
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STRUCTURE AND FUNCTION OF AMIDASE TOXIN - ANTITOXIN COMBINATIONS ASSOCIATED WITH THE TYPE VI SECRETION SYSTEM OF SERRATIA MARCESCENS.
Descriptor:SSP1 C50A MUTANT, GLYCEROL
Authors:Srikannathasan, V., English, G., Bui, N.K., Trunk, K., Rourke, P.E.F.O., Rao, V.A., Vollmer, W., Coulthurst, S.J., Hunter, W.N.
Deposit date:2013-04-09
Release date:2013-06-19
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural Basis for Type Vi Secreted Peptidoglycan Dl-Endopeptidase Function, Specificity and Neutralization in Serratia Marcescens
Acta Crystallogr.,Sect.D, 69, 2013
4BI8
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CRYSTAL STRUCTURE OF THE TYPE VI EFFECTOR-IMMUNITY COMPLEX SSP1-RAP1A FROM SERRATIA MARCESCENS
Descriptor:RAP1A, SSSP1
Authors:Srikannathasan, V., Coulthurst, S.J., Hunter, W.N.
Deposit date:2013-04-09
Release date:2013-06-19
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Type Vi Secreted Peptidoglycan Dl-Endopeptidase Function, Specificity and Neutralization in Serratia Marcescens
Acta Crystallogr.,Sect.D, 69, 2013
5A1H
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CRYSTAL STRUCTURE OF HUMAN SPINDLIN3
Descriptor:SPINDLIN-3
Authors:Srikannathasan, V., Gileadi, C., Johansson, C., Shrestha, L., Tallon, R., Burgess-Brown, N.A., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Oppermann, U.
Deposit date:2015-04-30
Release date:2015-06-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Human Spindlin3
To be Published
5A1L
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CRYSTAL STRUCTURE OF JMJC DOMAIN OF HUMAN HISTONE DEMETHYLASE UTY WITH S21056A
Descriptor:UBIQUITOUSLY TRANSCRIBED TETRATRICOPEPTIDE REPEAT PROTEIN Y-LINKED TRANSCRIPT VARIANT 57, FE (II) ION, 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propan-1-ol, ...
Authors:Srikannathasan, V., Gileadi, C., Johansson, C., Krojer, T., Tumber, A., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Brennan, P., Oppermann, U.
Deposit date:2015-05-01
Release date:2015-06-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Jmjc Domain of Human Histone Demethylase Uty with S21056A
To be Published
5LTU
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CRYSTAL STRUCTURE OF NUDT4A- DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE 2
Descriptor:Diphosphoinositol polyphosphate phosphohydrolase 2, 1,2-ETHANEDIOL
Authors:Srikannathasan, V., Nunez, C.A., Tallant, C., Siejka, P., Mathea, S., Newman, J., Strain-Damerell, C., Elkins, J.M., Burgess-Brown, N., Arrowsmith, C.H., Edwards, A.M., Bountra, C., von Delft, F., Huber, K.
Deposit date:2016-09-07
Release date:2017-09-20
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Crystal Structure of Human NUDT4A- Diphosphoinositol polyphosphate phosphohydrolase 2
To Be Published
5LUG
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CRYSTAL STRUCTURE OF HUMAN SPINDLIN-2B PROTEIN IN COMPLEX WITH ART(M3L)QTA(2MR)KS PEPTIDE
Descriptor:Spindlin-like protein 2, isoform CRA_a, ALA-ARG-THR-M3L-GLN-THR-ALA-2MR-LYS-SER, ...
Authors:Srikannathasan, V., Gileadi, C., Talon, R., Shrestha, L., Kopec, J., Szykowska, A., Burgess-Brown, N., Arrowsmith, C.H., Edwards, A.M., Bountra, C., von Delft, F., Oppermann, U., Huber, K.
Deposit date:2016-09-08
Release date:2017-09-20
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of human Spindlin-2B protein in complex with ART(M3L)QTA(2MR)KS peptide
To be published
5LW9
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CRYSTAL STRUCTURE OF HUMAN JARID1B IN COMPLEX WITH S40563A
Descriptor:Lysine-specific demethylase 5B,Lysine-specific demethylase 5B, ZINC ION, MANGANESE (II) ION, ...
Authors:Srikannathasan, V., Le Bihan, Y.V., Szykowska, A., Johansson, C., Gileadi, C., Arrowsmith, C.H., Edwards, A.M., Bountra, C., von Delft, F., Oppermann, U., Huber, K.
Deposit date:2016-09-15
Release date:2016-09-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of human JARID1B in complex with S40563a
to be published
5LWB
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CRYSTAL STRUCTURE OF HUMAN JARID1B IN COMPLEX WITH S40650A
Descriptor:Lysine-specific demethylase 5B,Lysine-specific demethylase 5B,Lysine-specific demethylase 5B, ZINC ION, MANGANESE (II) ION, ...
Authors:Srikannathasan, V., Le Bihan, Y.V., Szykowska, A., Johansson, C., Gileadi, C., Arrowsmith, C.H., Edwards, A.M., Bountra, C., von Delft, F., Oppermann, U., Huber, K.
Deposit date:2016-09-15
Release date:2016-10-26
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Crystal structure of human JARID1B in complex with S40650a
to be published
5T3P
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CRYSTAL STRUCTURE OF HUMAN PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7
Descriptor:Peroxisomal coenzyme A diphosphatase NUDT7, 1,2-ETHANEDIOL
Authors:Srikannathasan, V., Nunez, C.A., Tallant, C., Siejka, P., Mathea, S., Kopec, J., Elkins, J.M., Burgess-Brown, N., Arrowsmith, C.H., Edwards, A.M., Bountra, C., von Delft, F., Huber, K.
Deposit date:2016-08-26
Release date:2017-09-13
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystal structure of Human Peroxisomal coenzyme A diphosphatase NUDT7
To Be Published
6EIN
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CRYSTAL STRUCTURE OF KDM5B IN COMPLEX WITH S49365A.
Descriptor:Lysine-specific demethylase 5B,Lysine-specific demethylase 5B, 8-[4-[2-(4-propanoylpiperazin-1-yl)ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one, ZINC ION, ...
Authors:Srikannathasan, V., Newman, J.A., Szykowska, A., Wright, M., Ruda, G.F., Vazquez-Rodriguez, S.A., Kupinska, K., Strain-Damerell, C., Burgess-Brown, N.A., Arrowsmith, C.H., Edwards, A., Bountra, C., Oppermann, U., Huber, K., von Delft, F.
Deposit date:2017-09-19
Release date:2018-05-02
Last modified:2018-09-12
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Crystal structure of KDM5B in complex with S49365a.
To Be Published
6EIU
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CRYSTAL STRUCTURE OF KDM5B IN COMPLEX WITH KDOPZ29A
Descriptor:Lysine-specific demethylase 5B,Lysine-specific demethylase 5B, ZINC ION, MANGANESE (II) ION, ...
Authors:Srikannathasan, V., Newman, J.A., Szykowska, A., Wright, M., Ruda, G.F., Vazquez-Rodriguez, S.A., Kupinska, K., Strain-Damerell, C., Burgess-Brown, N.A., Arrowsmith, C.H., Edwards, A., Bountra, C., Oppermann, U., Huber, K., von Delft, F.
Deposit date:2017-09-19
Release date:2018-05-02
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal structure of KDM5B in complex with KDOPZ29a.
to be published
6EIY
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CRYSTAL STRUCTURE OF KDM5B IN COMPLEX WITH KDOPZ000034A.
Descriptor:Lysine-specific demethylase 5B,Lysine-specific demethylase 5B, ZINC ION, MANGANESE (II) ION, ...
Authors:Srikannathasan, V., Newman, J.A., Szykowska, A., Wright, M., Ruda, G.F., Vazquez-Rodriguez, S.A., Kupinska, K., Strain-Damerell, C., Burgess-Brown, N.A., Arrowsmith, C.H., Edwards, A., Bountra, C., Oppermann, U., Huber, K., von Delft, F.
Deposit date:2017-09-19
Release date:2018-05-02
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of KDM5B in complex with KDOPZ000034a.
to be published
6EJ0
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CRYSTAL STRUCTURE OF KDM5B IN COMPLEX WITH KDOPZ000049A.
Descriptor:Lysine-specific demethylase 5B,Lysine-specific demethylase 5B, ZINC ION, MANGANESE (II) ION, ...
Authors:Srikannathasan, V., Newman, J.A., Szykowska, A., Wright, M., Ruda, G.F., Vazquez-Rodriguez, S.A., Kupinska, K., Strain-Damerell, C., Burgess-Brown, N.A., Arrowsmith, C.H., Edwards, A., Bountra, C., Oppermann, U., Huber, K., von Delft, F.
Deposit date:2017-09-19
Release date:2018-05-02
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal structure of KDM5B in complex with KDOPZ000049a.
to be published
6EJ1
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CRYSTAL STRUCTURE OF KDM5B IN COMPLEX WITH KDOPZ48A.
Descriptor:Lysine-specific demethylase 5B,Lysine-specific demethylase 5B, ZINC ION, MANGANESE (II) ION, ...
Authors:Srikannathasan, V., Newman, J.A., Szykowska, A., Wright, M., Ruda, G.F., Vazquez-Rodriguez, S.A., Kupinska, K., Strain-Damerell, C., Burgess-Brown, N.A., Arrowsmith, C.H., Edwards, A., Bountra, C., Oppermann, U., Huber, K., von Delft, F.
Deposit date:2017-09-19
Release date:2018-05-02
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Crystal structure of KDM5B in complex with KDOPZ48a.
to be published
6EK6
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CRYSTAL STRUCTURE OF KDM5B IN COMPLEX WITH S49195A.
Descriptor:Lysine-specific demethylase 5B,Lysine-specific demethylase 5B, ZINC ION, MANGANESE (II) ION, ...
Authors:Srikannathasan, V., Szykowska, A., Newman, J.A., Ruda, G.F., Strain-Damerell, C., Burgess-Brown, N.A., Vazquez-Rodriguez, S., Wright, M., Brennan, P.E., Arrowsmith, C.H., Edwards, A., Bountra, C., Oppermann, U., Huber, K., von Delft, F.
Deposit date:2017-09-25
Release date:2018-03-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of KDM5B in complex with S49195a.
To be published
6EKK
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CRYSTAL STRUCTURE OF GEF DOMAIN OF DENND 1A IN COMPLEX WITH RAB GTPASE RAB35-GDP BOUND STATE.
Descriptor:DENN domain-containing protein 1A, Ras-related protein Rab-35, SULFATE ION, ...
Authors:Srikannathasan, V., Szykowska, A., Tallant, C., Strain-Damerell, C., Kopec, J., Kupinska, K., Mukhopadhyay, S., Gavin, M., Wang, D., Chalk, R., Burgess-Brown, N.A., Arrowsmith, C.H., Edwards, A., Bountra, C., von Delft, F., Huber, K.
Deposit date:2017-09-26
Release date:2018-10-17
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal structure of DENND1A-RAB35 complex with GDP bound state.
To be published
6I8Y
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CRYSTAL STRUCTURE OF SPINDLIN1 IN COMPLEX WITH THE METHYLTRANSFERASE INHIBITOR A366
Descriptor:Spindlin-1, 5'-methoxy-6'-[3-(pyrrolidin-1-yl)propoxy]spiro[cyclobutane-1,3'-indol]-2'-amine, 1,2-ETHANEDIOL, ...
Authors:Srikannathasan, V., Johansson, C., Gileadi, C., Shrestha, L., Sorrell, F.J., Krojer, T., Burgess-Brown, N.A., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Oppermann, U.C.T.
Deposit date:2018-11-21
Release date:2018-12-26
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Crystal structure of Spindlin1 in complex with the Methyltransferase inhibitor A366
To Be Published
4B6I
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CRYSTAL STRUCTURE RAP2B (SMA2266) FROM SERRATIA MARCESCENS
Descriptor:SMA2266
Authors:Srikannathasan, V., Hunter, W.N.
Deposit date:2012-08-13
Release date:2012-08-22
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:New Secreted Toxins and Immunity Proteins Encoded within the Type Vi Secretion System Gene Cluster of Serratia Marcescens.
Mol.Microbiol., 86, 2012
5CDM
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2.5A STRUCTURE OF QPT-1 WITH S.AUREUS DNA GYRASE AND DNA
Descriptor:DNA gyrase subunit B,DNA gyrase subunit B, DNA gyrase subunit A, DNA (5'-D(P*GP*AP*GP*CP*GP*TP*AP*C*GP*GP*CP*CP*GP*TP*AP*CP*GP*CP*TP*T)-3'), ...
Authors:Bax, B.D., Srikannathasan, V., Chan, P.F.
Deposit date:2015-07-04
Release date:2015-12-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.
Nat Commun, 6, 2015
5CDN
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2.8A STRUCTURE OF ETOPOSIDE WITH S.AUREUS DNA GYRASE AND DNA
Descriptor:DNA gyrase subunit A, DNA gyrase subunit B,DNA gyrase subunit B, DNA (5'-D(P*GP*AP*GP*CP*GP*TP*AP**GP*GP*CP*CP*GP*TP*AP*CP*GP*CP*TP*C)-3'), ...
Authors:Bax, B.D., Srikannathasan, V., Chan, P.F.
Deposit date:2015-07-04
Release date:2015-12-16
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.
Nat Commun, 6, 2015
5CDO
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3.15A STRUCTURE OF QPT-1 WITH S.AUREUS DNA GYRASE AND DNA
Descriptor:DNA gyrase subunit A, DNA gyrase subunit B,DNA gyrase subunit B, DNA (5'-D(P*GP*AP*GP*CP*GP*TP*AP*C*GP*GP*CP*CP*GP*TP*AP*CP*GP*CP*TP*T)-3'), ...
Authors:Bax, B.D., Srikannathasan, V., Chan, P.F.
Deposit date:2015-07-04
Release date:2015-12-16
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.
Nat Commun, 6, 2015
5CDP
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2.45A STRUCTURE OF ETOPOSIDE WITH S.AUREUS DNA GYRASE AND DNA
Descriptor:DNA gyrase subunit A, DNA gyrase subunit B, DNA (5'-D(*AP*GP*CP*CP*GP*TP*AP*G*GP*GP*TP*AP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3'), ...
Authors:Bax, B.D., Srikannathasan, V., Chan, P.F.
Deposit date:2015-07-04
Release date:2015-12-16
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.
Nat Commun, 6, 2015