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5E5V
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STRUCTURE OF AMYLOID FORMING PEPTIDE NFGAILS (RESIDUES 22-28) FROM ISLET AMYLOID POLYPEPTIDE
Descriptor:NFGAILS (22-28) from islet amyloid polypeptide, synthesized
Authors:Soriaga, A.B., Macdonald, R., Sawaya, M.R., Sangwan, S., Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
5E5X
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STRUCTURE OF THE AMYLOID FORMING PEPTIDE ANFLVH (RESIDUES 13-18) FROM ISLET AMYLOID POLYPEPTIDE
Descriptor:ANFLVH (residues 13-18) from islet amyloid polypeptide
Authors:Soriaga, A.B., Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
5E5Z
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STRUCTURE OF THE AMYLOID FORMING PEPTIDE LVHSSN (RESIDUES
Descriptor:LVHSSN (residues 16-21) from islet amyloid polypeptide
Authors:Soriaga, A.B., Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.664 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
5E61
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STRUCTURE OF AMYLOID-FORMING PEPTIDE FGAILSS (RESIDUES 23-29) FROM ISLET AMYLOID POLYPEPTIDE
Descriptor:FGAILSS (residues 23-29) from islet amyloid polypeptide
Authors:Soriaga, A.B., Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
3PZZ
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STRUCTURE OF AN AMYLOID FORMING PEPTIDE GAIIGL (29-34) FROM AMYLOID BETA
Descriptor:Amyloid beta A4 protein
Authors:Soriaga, A.B., Laganowsky, A.L., Sawaya, M.R., Eisenberg, D.
Deposit date:2010-12-14
Release date:2011-10-12
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Molecular basis for amyloid-beta polymorphism.
Proc.Natl.Acad.Sci.USA, 108, 2011
3Q2X
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STRUCTURE OF AN AMYLOID FORMING PEPTIDE NKGAII (RESIDUES 27-32) FROM AMYLOID BETA
Descriptor:Amyloid beta A4 protein
Authors:Soriaga, A.B., Sawaya, M.R., Eisenberg, D.
Deposit date:2010-12-20
Release date:2011-10-12
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:Molecular basis for amyloid-beta polymorphism.
Proc.Natl.Acad.Sci.USA, 108, 2011
3SB6
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CU-MEDIATED DIMER OF T4 LYSOZYME D61H/K65H/R76H/R80H BY SYNTHETIC SYMMETRIZATION
Descriptor:Lysozyme, COPPER (II) ION, CHLORIDE ION
Authors:Soriaga, A.B., Laganowsky, A., Zhao, M., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-03
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SB7
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CU-MEDIATED TRIMER OF T4 LYSOZYME D61H/K65H/R76H/R80H BY SYNTHETIC SYMMETRIZATION
Descriptor:Lysozyme, GLYCEROL, COPPER (II) ION
Authors:Soriaga, A.B., Laganowsky, A., Zhao, M., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-03
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SB8
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CU-MEDIATED DIMER OF T4 LYSOZYME D61H/K65H BY SYNTHETIC SYMMETRIZATION
Descriptor:Lysozyme, COPPER (II) ION
Authors:Soriaga, A.B., Laganowsky, A., Zhao, M., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-03
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SB9
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CU-MEDIATED DIMER OF T4 LYSOZYME R76H/R80H BY SYNTHETIC SYMMETRIZATION
Descriptor:Lysozyme, FORMIC ACID, COPPER (II) ION
Authors:Soriaga, A.B., Laganowsky, A., Zhao, M., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-03
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SBA
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ZN-MEDIATED HEXAMER OF T4 LYSOZYME R76H/R80H BY SYNTHETIC SYMMETRIZATION
Descriptor:Lysozyme, ZINC ION, CHLORIDE ION
Authors:Soriaga, A.B., Laganowsky, A., Zhao, M., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-03
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
4QXX
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STRUCTURE OF THE AMYLOID FORMING PEPTIDE GNLVS (RESIDUES 26-30) FROM THE EOSINOPHIL MAJOR BASIC PROTEIN (EMBP)
Descriptor:Bone marrow proteoglycan
Authors:Soriaga, A.B., Soragni, A., Sawaya, M.R., Eisenberg, D.
Deposit date:2014-07-22
Release date:2015-03-18
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (1.445 Å)
Cite:Toxicity of Eosinophil MBP Is Repressed by Intracellular Crystallization and Promoted by Extracellular Aggregation.
Mol.Cell, 57, 2015
4RP6
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STRUCTURE OF THE AMYLOID-FORMING SEGMENT LTIITLE FROM P53 (RESIDUES 252-258)
Descriptor:LTIITLE heptapeptide segment from p53
Authors:Soriaga, A.B., Soragni, A., Eisenberg, D.
Deposit date:2014-10-29
Release date:2016-01-13
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (1.703 Å)
Cite:A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas.
Cancer Cell, 29, 2016
4RP7
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STRUCTURE OF THE AMYLOID-FORMING SEGMENT TIITLE FROM P53 (RESIDUES 253-258)
Descriptor:TIITLE hexapeptide segment from p53, ZINC ION
Authors:Soriaga, A.B., Soragni, A., Eisenberg, D.
Deposit date:2014-10-29
Release date:2016-01-13
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (1.576 Å)
Cite:A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas.
Cancer Cell, 29, 2016
3SB5
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ZN-MEDIATED TRIMER OF T4 LYSOZYME R125C/E128C BY SYNTHETIC SYMMETRIZATION
Descriptor:Lysozyme, ZINC ION, CHLORIDE ION, ...
Authors:Laganowsky, A., Soriaga, A.B., Zhao, M., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-03
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SBB
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DISULPHIDE-MEDIATED TETRAMER OF T4 LYSOZYME R76C/R80C BY SYNTHETIC SYMMETRIZATION
Descriptor:Lysozyme, CHLORIDE ION
Authors:Laganowsky, A., Soriaga, A.B., Zhao, M., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-03
Release date:2011-09-21
Last modified:2015-01-28
Method:X-RAY DIFFRACTION (1.434 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SER
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ZN-MEDIATED POLYMER OF MALTOSE-BINDING PROTEIN K26H/K30H BY SYNTHETIC SYMMETRIZATION
Descriptor:Maltose-binding periplasmic protein, MALTOSE, CHLORIDE ION, ...
Authors:Zhao, M., Soriaga, A.B., Laganowsky, A., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-11
Release date:2011-09-21
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SES
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CU-MEDIATED DIMER OF MALTOSE-BINDING PROTEIN A216H/K220H BY SYNTHETIC SYMMETRIZATION
Descriptor:Maltose-binding periplasmic protein, MALTOSE, COPPER (II) ION, ...
Authors:Zhao, M., Soriaga, A.B., Laganowsky, A., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-11
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SET
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NI-MEDIATED DIMER OF MALTOSE-BINDING PROTEIN A216H/K220H BY SYNTHETIC SYMMETRIZATION (FORM I)
Descriptor:Maltose-binding periplasmic protein, MALTOSE, NICKEL (II) ION
Authors:Zhao, M., Soriaga, A.B., Laganowsky, A., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-11
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SEU
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ZN-MEDIATED POLYMER OF MALTOSE-BINDING PROTEIN A216H/K220H BY SYNTHETIC SYMMETRIZATION (FORM III)
Descriptor:Maltose-binding periplasmic protein, MALTOSE, ZINC ION, ...
Authors:Zhao, M., Soriaga, A.B., Laganowsky, A., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-11
Release date:2011-09-21
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SEV
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ZN-MEDIATED TRIMER OF MALTOSE-BINDING PROTEIN E310H/K314H BY SYNTHETIC SYMMETRIZATION
Descriptor:Maltose-binding periplasmic protein, MALTOSE, ZINC ION, ...
Authors:Zhao, M., Soriaga, A.B., Laganowsky, A., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-11
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SEW
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ZN-MEDIATED POLYMER OF MALTOSE-BINDING PROTEIN A216H/K220H BY SYNTHETIC SYMMETRIZATION (FORM I)
Descriptor:Maltose-binding periplasmic protein, MALTOSE, ZINC ION, ...
Authors:Zhao, M., Soriaga, A.B., Laganowsky, A., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-11
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SEX
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NI-MEDIATED DIMER OF MALTOSE-BINDING PROTEIN A216H/K220H BY SYNTHETIC SYMMETRIZATION (FORM II)
Descriptor:Maltose-binding periplasmic protein, MALTOSE, IODIDE ION, ...
Authors:Zhao, M., Soriaga, A.B., Laganowsky, A., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-11
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SEY
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ZN-MEDIATED POLYMER OF MALTOSE-BINDING PROTEIN A216H/K220H BY SYNTHETIC SYMMETRIZATION (FORM II)
Descriptor:Maltose-binding periplasmic protein, MALTOSE, ZINC ION, ...
Authors:Zhao, M., Soriaga, A.B., Laganowsky, A., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-11
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
2Y29
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STRUCTURE OF SEGMENT KLVFFA FROM THE AMYLOID-BETA PEPTIDE (AB, RESIDUES 16-21), ALTERNATE POLYMORPH III
Descriptor:AMYLOID BETA A4 PROTEIN
Authors:Colletier, J., Laganowsky, A., Sawaya, M.R., Eisenberg, D.
Deposit date:2010-12-14
Release date:2011-10-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular Basis for Amyloid-{Beta} Polymorphism.
Proc.Natl.Acad.Sci.USA, 108, 2011
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