Author results

4IQ6
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GSK-3BETA WITH INHIBITOR 6-CHLORO-N-CYCLOHEXYL-4-(1H-PYRROLO[2,3-B]PYRIDIN-3-YL)PYRIDIN-2-AMINE
Descriptor:Glycogen synthase kinase-3 beta, 6-chloro-N-cyclohexyl-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-amine
Authors:Tong, Y., Stewart, K.D., Florjancic, A.S., Harlan, J.E., Merta, P.J., Przytulinska, M., Soni, N., Swinger, K.S., Zhu, H., Johnson, E.F., Shoemaker, A.R., Penning, T.D.
Deposit date:2013-01-10
Release date:2013-04-24
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195.
ACS Med Chem Lett, 4, 2013
3JXW
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DISCOVERY OF 3H-BENZO[4,5]THIENO[3,2-D]PYRIMIDIN-4-ONES AS POTENT, HIGHLY SELECTIVE AND ORALLY BIOAVAILABLE PIM KINASES INHIBITORS
Descriptor:Proto-oncogene serine/threonine-protein kinase Pim-1, 8-[(E)-2-cyclopropylethenyl]-2-[(dimethylamino)methyl][1]benzothieno[3,2-d]pyrimidin-4(3H)-one
Authors:Stoll, V.S.
Deposit date:2009-09-21
Release date:2009-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery of 3H-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective and Orally Bioavailable Pim Kinases Inhibitors
TO BE PUBLISHED
3JY0
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DISCOVERY OF 3H-BENZO[4,5]THIENO[3,2-D]PYRIMIDIN-4-ONES AS POTENT, HIGHLY SELECTIVE AND ORALLY BIOAVAILABLE PIM KINASES INHIBITORS
Descriptor:Proto-oncogene serine/threonine-protein kinase Pim-1, 8-chloro-2-{[(3S)-3-hydroxypyrrolidin-1-yl]methyl}[1]benzothieno[3,2-d]pyrimidin-4(3H)-one
Authors:Stoll, V.S.
Deposit date:2009-09-21
Release date:2009-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery of 3H-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective and Orally Bioavailable Pim Kinases Inhibitors
To be Published
3JYA
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DISCOVERY OF 3H-BENZO[4,5]THIENO[3,2-D]PYRIMIDIN-4-ONES AS POTENT, HIGHLY SELECTIVE AND ORALLY BIOAVAILABLE PIM KINASES INHIBITORS
Descriptor:Proto-oncogene serine/threonine-protein kinase Pim-1, 6,9-dichloro[1]benzothieno[3,2-d]pyrimidin-4(3H)-one
Authors:Stoll, V.S.
Deposit date:2009-09-21
Release date:2009-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery of 3H-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective and Orally Bioavailable Pim Kinases Inhibitors
TO BE PUBLISHED
5JZC
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HELICAL FILAMENT
Descriptor:DNA repair protein RAD51 homolog 1
Authors:Short, J., Liu, Y.
Deposit date:2016-05-16
Release date:2016-09-21
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy.
Nucleic Acids Res., 44, 2016
5NP7
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CRYOEM STRUCTURE OF HUMAN RAD51 ON SINGLE-STRANDED DNA TO 4.2A RESOLUTION.
Descriptor:DNA repair protein RAD51 homolog 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Short, J.M., Venkitaraman, A.
Deposit date:2017-04-13
Release date:2017-05-03
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy.
Nucleic Acids Res., 44, 2016