Author results

2JOO
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THE NMR SOLUTION STRUCTURE OF RECOMBINANT RGD-HIRUDIN
分子名称:Hirudin variant-1
著者Song, X., Mo, W., Liu, X., Yan, X., Song, H., Dai, L.
登録日2007-03-14
公開日2008-03-18
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The NMR solution structure of recombinant RGD-hirudin
Biochem.Biophys.Res.Commun., 360, 2007
4F7G
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CRYSTAL STRUCTURE OF TALIN AUTOINHIBITION COMPLEX
分子名称:Talin-1
著者Song, X., Qin, J., Ye, S., Zhang, R.
登録日2012-05-16
公開日2012-07-04
最終更新日2012-11-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion.
Cell Res., 22, 2012
5UN1
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CRYSTAL STRUCTURE OF GLUN1/GLUN2B DELTA-ATD NMDA RECEPTOR
分子名称:N-methyl-D-aspartate receptor subunit NR1-3a, Ionotropic glutamate receptor subunit NR2B, GLYCINE, ...
著者Song, X., Gouaux, E.
登録日2017-01-30
公開日2018-02-07
最終更新日2018-05-02
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Mechanism of NMDA receptor channel block by MK-801 and memantine.
Nature, 556, 2018
4OUL
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CRYSTAL STRUCTURE OF HUMAN CAPRIN-2 C1Q DOMAIN
分子名称:Caprin-2, CALCIUM ION, GLYCEROL
著者Song, X., Li, L.
登録日2014-02-17
公開日2014-10-29
最終更新日2015-04-08
実験手法X-RAY DIFFRACTION (1.949 Å)
主引用文献Structural insights into the C1q domain of Caprin-2 in canonical Wnt signaling
J.Biol.Chem., 289, 2014
4OUM
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CRYSTAL STRUCTURE OF HUMAN CAPRIN-2 C1Q DOMAIN
分子名称:Caprin-2, TETRAETHYLENE GLYCOL, CITRATE ANION, ...
著者Song, X., Li, L.
登録日2014-02-18
公開日2014-10-29
最終更新日2015-04-08
実験手法X-RAY DIFFRACTION (1.491 Å)
主引用文献Structural insights into the C1q domain of Caprin-2 in canonical Wnt signaling
J.Biol.Chem., 289, 2014
4OUS
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CRYSTAL STRUCTURE OF ZEBRAFISH CAPRIN-2 C1Q DOMAIN
分子名称:Caprin-2, CALCIUM ION
著者Song, X., Li, L.
登録日2014-02-18
公開日2014-10-29
最終更新日2015-04-08
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Structural insights into the C1q domain of Caprin-2 in canonical Wnt signaling
J.Biol.Chem., 289, 2014
2B3O
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CRYSTAL STRUCTURE OF HUMAN TYROSINE PHOSPHATASE SHP-1
分子名称:Tyrosine-protein phosphatase, non-receptor type 6
著者Yang, J., Liu, L., He, D., Song, X., Liang, X., Zhao, Z.J., Zhou, G.W.
登録日2005-09-20
公開日2005-10-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of human protein-tyrosine phosphatase SHP-1.
J.Biol.Chem., 278, 2003
2F7Z
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PROTEIN KINASE A BOUND TO (R)-1-(1H-INDOL-3-YLMETHYL)-2-(2-PYRIDIN-4-YL-[1,7]NAPHTYRIDIN-5-YLOXY)-EHYLAMINE
分子名称:cAMP-dependent protein kinase, alpha-catalytic subunit, PKI, ...
著者Li, Q., Woods, K.W., Thomas, S., Zhu, G.D., Packard, G., Fisher, J., Li, T., Gong, J., Dinges, J., Song, X., Abrams, J., Luo, Y., Johnson, E.F., Shi, Y., Liu, X., Klinghofer, V., Des Jong, R., Oltersdorf, T., Stoll, V.S., Jakob, C.G., Rosenberg, S.H., Giranda, V.L.
登録日2005-12-01
公開日2006-06-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer.
Bioorg.Med.Chem.Lett., 16, 2006
2MDT
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A PILT N-TERMINUS DOMAIN PROTEIN SSO1118 FROM HYPERTHEMOPHILIC ARCHAEON SULFOLOBUS SOLFATARICUS P2
分子名称:Putative uncharacterized protein
著者Xuan, J., Song, X., Wang, J., Feng, Y.
登録日2013-09-17
公開日2013-11-20
最終更新日2013-12-25
実験手法SOLUTION NMR
主引用文献A PilT N-terminus domain protein SSO1118 from hyperthemophilic archaeon Sulfolobus solfataricus P2
J.Biomol.Nmr, 57, 2013
2O1Y
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SOLUTION STRUCTURE OF THE ANTI-APOPTOTIC PROTEIN BCL-XL IN COMPLEX WITH AN ACYL-SULFONAMIDE-BASED LIGAND
分子名称:Apoptosis regulator Bcl-X, 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE
著者Bruncko, M., Oost, T.K., Belli, B.A., Ding, H., Joseph, M.K., Kunzer, A., Martineau, D., McClellan, W.J., Mitten, M., Ng, S.C., Nimmer, P.M., Oltersdorf, T., Park, C.M., Petros, A.M., Shoemaker, A.R., Song, X., Wang, X., Wendt, M.D., Zhang, H., Fesik, S.W., Rosenberg, S.H., Elmore, S.W.
登録日2006-11-29
公開日2007-02-27
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL.
J.Med.Chem., 50, 2007
2O21
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SOLUTION STRUCTURE OF THE ANTI-APOPTOTIC PROTEIN BCL-2 IN COMPLEX WITH AN ACYL-SULFONAMIDE-BASED LIGAND
分子名称:Apoptosis regulator Bcl-2, 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE
著者Bruncko, M., Oost, T.K., Belli, B.A., Ding, H., Joseph, M.K., Kunzer, A., Martineau, D., McClellan, W.J., Mitten, M., Ng, S.C., Nimmer, P.M., Oltersdorf, T., Park, C.M., Petros, A.M., Shoemaker, A.R., Song, X., Wang, X., Wendt, M.D., Zhang, H., Fesik, S.W., Rosenberg, S.H., Elmore, S.W.
登録日2006-11-29
公開日2007-02-27
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL.
J.Med.Chem., 50, 2007
2O22
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SOLUTION STRUCTURE OF THE ANTI-APOPTOTIC PROTEIN BCL-2 IN COMPLEX WITH AN ACYL-SULFONAMIDE-BASED LIGAND
分子名称:Apoptosis regulator Bcl-2, N-[(4-{[1,1-dimethyl-2-(phenylthio)ethyl]amino}-3-nitrophenyl)sulfonyl]-4-(4,4-dimethylpiperidin-1-yl)benzamide
著者Bruncko, M., Oost, T.K., Belli, B.A., Ding, H., Joseph, M.K., Kunzer, A., Martineau, D., McClellan, W.J., Mitten, M., Ng, S.C., Nimmer, P.M., Oltersdorf, T., Park, C.M., Petros, A.M., Shoemaker, A.R., Song, X., Wang, X., Wendt, M.D., Zhang, H., Fesik, S.W., Rosenberg, S.H., Elmore, S.W.
登録日2006-11-29
公開日2007-02-27
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL.
J.Med.Chem., 50, 2007
2O2F
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SOLUTION STRUCTURE OF THE ANTI-APOPTOTIC PROTEIN BCL-2 IN COMPLEX WITH AN ACYL-SULFONAMIDE-BASED LIGAND
分子名称:Apoptosis regulator Bcl-2, 4-(4-BENZYL-4-METHOXYPIPERIDIN-1-YL)-N-[(4-{[1,1-DIMETHYL-2-(PHENYLTHIO)ETHYL]AMINO}-3-NITROPHENYL)SULFONYL]BENZAMIDE
著者Bruncko, M., Oost, T.K., Belli, B.A., Ding, H., Joseph, M.K., Kunzer, A., Martineau, D., McClellan, W.J., Mitten, M., Ng, S.C., Nimmer, P.M., Oltersdorf, T., Park, C.M., Petros, A.M., Shoemaker, A.R., Song, X., Wang, X., Wendt, M.D., Zhang, H., Fesik, S.W., Rosenberg, S.H., Elmore, S.W.
登録日2006-11-29
公開日2007-02-27
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL.
J.Med.Chem., 50, 2007
2O2M
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SOLUTION STRUCTURE OF THE ANTI-APOPTOTIC PROTEIN BCL-XL IN COMPLEX WITH AN ACYL-SULFONAMIDE-BASED LIGAND
分子名称:Apoptosis regulator Bcl-X, 4-(4-BENZYL-4-METHOXYPIPERIDIN-1-YL)-N-[(4-{[1,1-DIMETHYL-2-(PHENYLTHIO)ETHYL]AMINO}-3-NITROPHENYL)SULFONYL]BENZAMIDE
著者Bruncko, M., Oost, T.K., Belli, B.A., Ding, H., Joseph, M.K., Kunzer, A., Martineau, D., McClellan, W.J., Mitten, M., Ng, S.C., Nimmer, P.M., Oltersdorf, T., Park, C.M., Petros, A.M., Shoemaker, A.R., Song, X., Wang, X., Wendt, M.D., Zhang, H., Fesik, S.W., Rosenberg, S.H., Elmore, S.W.
登録日2006-11-30
公開日2007-02-27
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL.
J.Med.Chem., 50, 2007
2O2N
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SOLUTION STRUCTURE OF THE ANTI-APOPTOTIC PROTEIN BCL-XL IN COMPLEX WITH AN ACYL-SULFONAMIDE-BASED LIGAND
分子名称:Apoptosis regulator Bcl-X, 4-[4-(BIPHENYL-2-YLMETHYL)PIPERAZIN-1-YL]-N-[(4-{[1,1-DIMETHYL-2-(PHENYLTHIO)ETHYL]AMINO}-3-NITROPHENYL)SULFONYL]BENZAMIDE
著者Bruncko, M., Oost, T.K., Belli, B.A., Ding, H., Joseph, M.K., Kunzer, A., Martineau, D., McClellan, W.J., Mitten, M., Ng, S.C., Nimmer, P.M., Oltersdorf, T., Park, C.M., Petros, A.M., Shoemaker, A.R., Song, X., Wang, X., Wendt, M.D., Zhang, H., Fesik, S.W., Rosenberg, S.H., Elmore, S.W.
登録日2006-11-30
公開日2007-02-27
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL.
J.Med.Chem., 50, 2007
2UZT
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PKA STRUCTURES OF AKT, INDAZOLE-PYRIDINE INHIBITORS
分子名称:CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, ...
著者Zhu, G.D., Gandhi, V.B., Gong, J., Thomas, S., Woods, K.W., Song, X., Li, T., Diebold, R.B., Luo, Y., Liu, X., Guan, R., Klinghofer, V., Johnson, E.F., Bouska, J., Olson, A., Marsh, K.C., Stoll, V.S., Mamo, M., Polakowski, J., Campbell, T.J., Penning, T.D., Li, Q., Rosenberg, S.H., Giranda, V.L.
登録日2007-05-01
公開日2007-06-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Syntheses of Potent, Selective, and Orally Bioavailable Indazole-Pyridine Series of Protein Kinase B/Akt Inhibitors with Reduced Hypotension.
J.Med.Chem., 50, 2007
2UZU
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PKA STRUCTURES OF INDAZOLE-PYRIDINE SERIES OF AKT INHIBITORS
分子名称:CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, ...
著者Zhu, G.D., Gandhi, V.B., Gong, J., Thomas, S., Woods, K.W., Song, X., Li, T., Diebold, R.B., Luo, Y., Liu, X., Guan, R., Klinghofer, V., Johnson, E.F., Bouska, J., Olson, A., Marsh, K.C., Stoll, V.S., Mamo, M., Polakowski, J., Campbell, T.J., Penning, T.D., Li, Q., Rosenberg, S.H., Giranda, V.L.
登録日2007-05-01
公開日2007-06-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Syntheses of Potent, Selective, and Orally Bioavailable Indazole-Pyridine Series of Protein Kinase B/Akt Inhibitors with Reduced Hypotension.
J.Med.Chem., 50, 2007
2UZV
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PKA STRUCTURES OF INDAZOLE-PYRIDINE SERIES OF AKT INHIBITORS
分子名称:CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA,, CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT, ...
著者Zhu, G.D., Gandhi, V.B., Gong, J., Thomas, S., Woods, K.W., Song, X., Li, T., Diebold, R.B., Luo, Y., Liu, X., Guan, R., Klinghofer, V., Johnson, E.F., Bouska, J., Olson, A., Marsh, K.C., Stoll, V.S., Mamo, M., Polakowski, J., Campbell, T.J., Penning, T.D., Li, Q., Rosenberg, S.H., Giranda, V.L.
登録日2007-05-01
公開日2007-06-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Syntheses of Potent, Selective, and Orally Bioavailable Indazole-Pyridine Series of Protein Kinase B/Akt Inhibitors with Reduced Hypotension.
J.Med.Chem., 50, 2007
2UZW
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PKA STRUCTURES OF INDAZOLE-PYRIDINE SERIES OF AKT INHIBITORS
分子名称:CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, ...
著者Zhu, G.D., Gandhi, V.B., Gong, J., Thomas, S., Woods, K.W., Song, X., Li, T., Diebold, R.B., Luo, Y., Liu, X., Guan, R., Klinghofer, V., Johnson, E.F., Bouska, J., Olson, A., Marsh, K.C., Stoll, V.S., Mamo, M., Polakowski, J., Campbell, T.J., Penning, T.D., Li, Q., Rosenberg, S.H., Giranda, V.L.
登録日2007-05-01
公開日2007-06-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Syntheses of Potent, Selective, and Orally Bioavailable Indazole-Pyridine Series of Protein Kinase B/Akt Inhibitors with Reduced Hypotension.
J.Med.Chem., 50, 2007
1SV2
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CRYSTAL STRUCTURE OF PEPTIDE DEFORMYLASE FROM LEPTOSPIRA INTERROGANS (LIPDF) AT PH7.5
分子名称:Peptide deformylase, ZINC ION, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ...
著者Zhou, Z., Song, X., Li, Y., Gong, W.
登録日2004-03-27
公開日2005-08-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Novel conformational states of peptide deformylase from pathogenic bacterium Leptospira interrogans: implications for population shift
J.Biol.Chem., 280, 2005
1SZZ
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CRYSTAL STRUCTURE OF PEPTIDE DEFORMYLASE FROM LEPTOSPIRA INTERROGANS COMPLEXED WITH INHIBITOR ACTINONIN
分子名称:Peptide deformylase, ZINC ION, ACTINONIN
著者Zhou, Z., Song, X., Li, Y., Gong, W.
登録日2004-04-06
公開日2005-08-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Novel conformational states of peptide deformylase from pathogenic bacterium Leptospira interrogans: implications for population shift
J.Biol.Chem., 280, 2005
1VEV
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CRYSTAL STRUCTURE OF PEPTIDE DEFORMYLASE FROM LEPTOSPIRA INTERROGANS (LIPDF) AT PH6.5
分子名称:Peptide deformylase, ZINC ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者Zhou, Z., Song, X., Li, Y., Gong, W.
登録日2004-04-06
公開日2005-08-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Novel conformational states of peptide deformylase from pathogenic bacterium Leptospira interrogans: implications for population shift
J.Biol.Chem., 280, 2005
1VEY
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CRYSTAL STRUCTURE OF PEPTIDE DEFORMYLASE FROM LEPTOSPIRA INTERROGANS (LIPDF) AT PH7.0
分子名称:Peptide deformylase, ZINC ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
著者Zhou, Z., Song, X., Li, Y., Gong, W.
登録日2004-04-06
公開日2005-08-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Novel conformational states of peptide deformylase from pathogenic bacterium Leptospira interrogans: implications for population shift
J.Biol.Chem., 280, 2005
1VEZ
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CRYSTAL STRUCTURE OF PEPTIDE DEFORMYLASE FROM LEPTOSPIRA INTERROGANS(LIPDF) AT PH8.0
分子名称:Peptide deformylase, ZINC ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Zhou, Z., Song, X., Li, Y., Gong, W.
登録日2004-04-06
公開日2005-08-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Novel conformational states of peptide deformylase from pathogenic bacterium Leptospira interrogans: implications for population shift
J.Biol.Chem., 280, 2005
1Y6H
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CRYSTAL STRUCTURE OF LIPDF
分子名称:Peptide deformylase, ZINC ION, FORMIC ACID, ...
著者Zhou, Z., Song, X., Li, Y., Gong, W.
登録日2004-12-06
公開日2004-12-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Unique structural characteristics of peptide deformylase from pathogenic bacterium Leptospira interrogans
J.Mol.Biol., 339, 2004