1R62 | | CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF THE TWO-COMPONENT SYSTEM TRANSMITTER PROTEIN NRII (NTRB) | | Descriptor: | Nitrogen regulation protein NR(II) | | Authors: | Song, Y., Peisach, D., Pioszak, A.A., Xu, Z., Ninfa, A.J. | | Deposit date: | 2003-10-14 | | Release date: | 2004-06-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal Structure of the C-terminal Domain of the Two-Component System Transmitter Protein Nitrogen Regulator II (NRII; NtrB), Regulator of Nitrogen Assimilation in Escherichia coli.
Biochemistry, 43, 2004
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5HDM | | CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA GLUTAMATE-1-SEMIALDEHYDE-2,1-AMINOMUTASE | | Descriptor: | Glutamate-1-semialdehyde 2,1-aminomutase 1, chloroplastic, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ... | | Authors: | Song, Y., Pu, H., Liu, L. | | Deposit date: | 2016-01-05 | | Release date: | 2016-06-15 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Crystal structure of glutamate-1-semialdehyde-2,1-aminomutase from Arabidopsis thaliana
Acta Crystallogr.,Sect.F, 72, 2016
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5X7L | |
5YH1 | |
5YHX | | STRUCTURE OF LACTOCOCCUS LACTIS ZITR, WILD TYPE | | Descriptor: | Zinc transport transcriptional regulator, ZINC ION | | Authors: | Song, Y., Liu, H., Zhu, R., Yi, C., Chen, P. | | Deposit date: | 2017-10-01 | | Release date: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of Lactococcus lactis ZitR
Proc.Natl.Acad.Sci.Usa, 2017
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5YHY | | STRUCTURE OF LACTOCOCCUS LACTIS ZITR, C30S MUTANT | | Descriptor: | Zinc transport transcriptional regulator, ZINC ION | | Authors: | Song, Y., Liu, H., Zhu, R., Yi, C., Chen, P. | | Deposit date: | 2017-10-01 | | Release date: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure of Lactococcus lactis ZitR
Proc.Natl.Acad.Sci.Usa, 2017
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5YHZ | | STRUCTURE OF LACTOCOCCUS LACTIS ZITR, E41A MUTANT | | Descriptor: | Zinc transport transcriptional regulator, ZINC ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | | Authors: | Song, Y., Liu, H., Zhu, R., Yi, C., Chen, P. | | Deposit date: | 2017-10-01 | | Release date: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of Lactococcus lactis ZitR
Proc.Natl.Acad.Sci.Usa, 2017
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5YI0 | | STRUCTURE OF LACTOCOCCUS LACTIS ZITR, C30AH42A MUTANT | | Descriptor: | Zinc transport transcriptional regulator, ZINC ION | | Authors: | Song, Y., Liu, H., Zhu, R., Yi, C., Chen, P. | | Deposit date: | 2017-10-01 | | Release date: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of Lactococcus lactis ZitR
Proc.Natl.Acad.Sci.Usa, 2017
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5YI1 | | STRUCTURE OF LACTOCOCCUS LACTIS ZITR, C30AH42A MUTANT IN APO FORM | | Descriptor: | Zinc transport transcriptional regulator | | Authors: | Song, Y., Liu, H., Zhu, R., Yi, C., Chen, P. | | Deposit date: | 2017-10-01 | | Release date: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of Lactococcus lactis ZitR
Proc.Natl.Acad.Sci.Usa, 2017
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5YI2 | | STRUCTURE OF LACTOCOCCUS LACTIS ZITR, WILD TYPE IN COMPLEX WITH DNA | | Descriptor: | Zinc transport transcriptional regulator, DNA (5'-D(*TP*GP*TP*TP*AP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*A)-3'), ZINC ION | | Authors: | Song, Y., Liu, H., Zhu, R., Yi, C., Chen, P. | | Deposit date: | 2017-10-01 | | Release date: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of Lactococcus lactis ZitR
Proc.Natl.Acad.Sci.Usa, 2017
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5YI3 | | STRUCTURE OF LACTOCOCCUS LACTIS ZITR, C30S MUTANT IN COMPLEX WITH DNA | | Descriptor: | Zinc transport transcriptional regulator, DNA (5'-D(*TP*GP*TP*TP*AP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*A)-3'), ZINC ION | | Authors: | Song, Y., Liu, H., Zhu, R., Yi, C., Chen, P. | | Deposit date: | 2017-10-01 | | Release date: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure of Lactococcus lactis ZitR
Proc.Natl.Acad.Sci.Usa, 2017
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5V58 | |
5V59 | |
5XOR | |
5CVC | | STRUCTURE OF MAIZE SERINE RACEMASE | | Descriptor: | Serine racemase, MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Song, Y., Zou, L., Fan, J. | | Deposit date: | 2015-07-26 | | Release date: | 2016-03-16 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Crystal structure of maize serine racemase with pyridoxal 5'-phosphate.
Acta Crystallogr.,Sect.F, 72, 2016
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5VBL | | STRUCTURE OF APELIN RECEPTOR IN COMPLEX WITH AGONIST PEPTIDE | | Descriptor: | agonist peptide, Apelin receptor,Rubredoxin,Apelin receptor Chimera, ZINC ION, ... | | Authors: | Ma, Y., Yue, Y., Ma, Y., Zhang, Q., Zhou, Q., Song, Y., Shen, Y., Li, X., Ma, X., Li, C., Hanson, M.A., Han, G.W., Sickmier, E.A., Swaminath, G., Zhao, S., Stevems, R.C., Hu, L.A., Zhong, W., Zhang, M., Xu, F. | | Deposit date: | 2017-03-29 | | Release date: | 2017-05-31 | | Last modified: | 2017-07-19 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural Basis for Apelin Control of the Human Apelin Receptor
Structure, 25, 2017
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5WYD | | STRUCTURAL OF PSEUDOMONAS AERUGINOSA DSPI | | Descriptor: | Probable enoyl-CoA hydratase/isomerase, PENTANEDIAL, ISOPROPYL ALCOHOL, ... | | Authors: | Liu, L., Peng, C., Li, T., Li, C., He, L., Song, Y., Zhu, Y., Shen, Y., Bao, R. | | Deposit date: | 2017-01-12 | | Release date: | 2018-01-31 | | Last modified: | 2018-03-07 | | Method: | X-RAY DIFFRACTION (2.101 Å) | | Cite: | Functional and structural characterization of Pseudomonas aeruginosa DspI verified its role in pathogenicity via the modulation of diffusible signal factor (DSF) biosynthesis
To Be Published
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3SR4 | | CRYSTAL STRUCTURE OF HUMAN DOT1L IN COMPLEX WITH A SELECTIVE INHIBITOR | | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-79 specific, (2S)-2-azanyl-4-[[(2S,3S,4R,5R)-5-[6-(methylamino)purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]butanoic acid, ... | | Authors: | Diao, J., Chen, P., Yao, Y., Prasad, B.V.V., Song, Y. | | Deposit date: | 2011-07-06 | | Release date: | 2011-10-05 | | Last modified: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Selective Inhibitors of Histone Methyltransferase DOT1L: Design, Synthesis, and Crystallographic Studies.
J.Am.Chem.Soc., 133, 2011
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4I3K | | CRYSTAL STRUCTURE OF A METABOLIC REDUCTASE WITH 1-HYDROXY-6-(4-HYDROXYBENZYL)-4-METHYLPYRIDIN-2(1H)-ONE | | Descriptor: | Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... | | Authors: | Zheng, B., Yao, Y., Liu, Z., Deng, L., Anglin, J.L., Jiang, H., Prasad, B.V.V., Song, Y. | | Deposit date: | 2012-11-26 | | Release date: | 2013-05-22 | | Last modified: | 2013-07-10 | | Method: | X-RAY DIFFRACTION (3.3056 Å) | | Cite: | Crystallographic Investigation and Selective Inhibition of Mutant Isocitrate Dehydrogenase.
ACS Med Chem Lett, 4, 2013
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4I3L | | CRYSTAL STRUCTURE OF A METABOLIC REDUCTASE WITH 6-BENZYL-1-HYDROXY-4-METHYLPYRIDIN-2(1H)-ONE | | Descriptor: | Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... | | Authors: | Zheng, B., Yao, Y., Liu, Z., Deng, L., Anglin, J.L., Jiang, H., Prasad, B.V.V., Song, Y. | | Deposit date: | 2012-11-26 | | Release date: | 2013-05-22 | | Last modified: | 2013-07-10 | | Method: | X-RAY DIFFRACTION (3.292 Å) | | Cite: | Crystallographic Investigation and Selective Inhibition of Mutant Isocitrate Dehydrogenase.
ACS Med Chem Lett, 4, 2013
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4XRX | | CRYSTAL STRUCTURE OF A METABOLIC REDUCTASE WITH (E)-5-((1-METHYL-5-OXO-2-THIOXOIMIDAZOLIDIN-4-YLIDENE)METHYL)PYRIDIN-2(1H)-ONE | | Descriptor: | Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 5-[(E)-(1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl]pyridin-2(1H)-one | | Authors: | Zheng, B., Wu, F., Jiang, H., Kogiso, M., Yao, Y., Zhou, C., Li, X., Song, Y. | | Deposit date: | 2015-01-21 | | Release date: | 2015-12-09 | | Last modified: | 2017-09-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds.
J.Med.Chem., 58, 2015
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4XS3 | | CRYSTAL STRUCTURE OF A METABOLIC REDUCTASE WITH (E)-1-BENZYL-5-((1-METHYL-5-OXO-2-THIOXOIMIDAZOLIDIN-4-YLIDENE)METHYL)PYRIDIN-2(1H)-ONE | | Descriptor: | Isocitrate dehydrogenase [NADP] cytoplasmic, (E)-1-benzyl-5-((1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)pyridin-2(1H)-one, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Zheng, B., Wu, F., Jiang, H., Kogiso, M., Yao, Y., Zhou, C., Li, X., Song, Y. | | Deposit date: | 2015-01-21 | | Release date: | 2016-07-27 | | Last modified: | 2017-09-13 | | Method: | X-RAY DIFFRACTION (3.291 Å) | | Cite: | Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds.
J.Med.Chem., 58, 2015
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3RAS | | CRYSTAL STRUCTURE OF 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE (DXR) COMPLEXED WITH A LIPOPHILIC PHOSPHONATE INHIBITOR | | Descriptor: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-(N-HYDROXYACETAMIDO)-1-(3,4-DICHLOROPHENYL)PROPYLPHOSPHONIC ACID, ... | | Authors: | Diao, J., Deng, L., Prasad, B.V.V., Song, Y. | | Deposit date: | 2011-03-28 | | Release date: | 2011-05-25 | | Last modified: | 2012-07-25 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase by lipophilic phosphonates: SAR, QSAR, and crystallographic studies.
J.Med.Chem., 54, 2011
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4GAE | | CRYSTAL STRUCTURE OF PLASMODIUM DXR IN COMPLEX WITH A PYRIDINE-CONTAINING INHIBITOR | | Descriptor: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplast, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Diao, J., Xue, J., Cai, G., Deng, L., Song, Y. | | Deposit date: | 2012-07-25 | | Release date: | 2013-02-06 | | Last modified: | 2013-07-10 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Antimalarial and Structural Studies of Pyridine-containing Inhibitors of 1-Deoxyxylulose-5-phosphate Reductoisomerase.
ACS Med Chem Lett, 4, 2013
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2LP1 | | THE SOLUTION NMR STRUCTURE OF THE TRANSMEMBRANE C-TERMINAL DOMAIN OF THE AMYLOID PRECURSOR PROTEIN (C99) | | Descriptor: | C99 | | Authors: | Barrett, P.J., Song, Y., Van Horn, W.D., Hustedt, E.J., Schafer, J.M., Hadziselimovic, A., Beel, A.J., Sanders, C.R. | | Deposit date: | 2012-01-30 | | Release date: | 2012-06-06 | | Last modified: | 2012-06-20 | | Method: | SOLUTION NMR | | Cite: | The amyloid precursor protein has a flexible transmembrane domain and binds cholesterol.
Science, 336, 2012
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