Author results

1R62
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF THE TWO-COMPONENT SYSTEM TRANSMITTER PROTEIN NRII (NTRB)
Descriptor:Nitrogen regulation protein NR(II)
Authors:Song, Y., Peisach, D., Pioszak, A.A., Xu, Z., Ninfa, A.J.
Deposit date:2003-10-14
Release date:2004-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of the C-terminal Domain of the Two-Component System Transmitter Protein Nitrogen Regulator II (NRII; NtrB), Regulator of Nitrogen Assimilation in Escherichia coli.
Biochemistry, 43, 2004
5HDM
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CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA GLUTAMATE-1-SEMIALDEHYDE-2,1-AMINOMUTASE
Descriptor:Glutamate-1-semialdehyde 2,1-aminomutase 1, chloroplastic, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ...
Authors:Song, Y., Pu, H., Liu, L.
Deposit date:2016-01-05
Release date:2016-06-15
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal structure of glutamate-1-semialdehyde-2,1-aminomutase from Arabidopsis thaliana.
Acta Crystallogr.,Sect.F, 72, 2016
5X7L
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STRUCTURE OF TSRD FROM STREPTOMYCES LAURENTII
Descriptor:TsrD, ISOPROPYL ALCOHOL
Authors:Song, Y., Lin, Z., Deng, W., Liu, W.
Deposit date:2017-02-27
Release date:2018-03-07
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Structure of TsrD from Streptomyces laurentii
To Be Published
5YH1
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MEMBER OF S1P FAMILY OF RIBOSOMAL PROTEINS PF0399 DHH DOMAIN
Descriptor:Member of s1p family of ribosomal proteins, GLYCEROL, MANGANESE (II) ION
Authors:Song, Y., Liu, X.P.
Deposit date:2017-09-27
Release date:2018-08-01
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Member of s1p family of ribosomal proteins PF0399 DHH domain
To Be Published
6J3A
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STRUCTURE OF LMBA2991HD
Descriptor:Gamma-glutamyltranspeptidase
Authors:Song, Y.
Deposit date:2019-01-04
Release date:2020-01-15
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structure of LmbA2991HD
To Be Published
6J3I
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STRUCTURE OF LMBA2991T421A
Descriptor:Gamma-glutamyltranspeptidase
Authors:Song, Y.
Deposit date:2019-01-04
Release date:2020-01-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of LmbA2991T421A
To Be Published
6ITX
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STRUCTURE OF THE C-TERMINAL HEAD DOMAIN OF THE AVIAN ADENOVIRUS EDSV FIBER
Descriptor:Fiber protein, GLUTAMINE, SULFATE ION
Authors:Wei, Q., Song, Y.
Deposit date:2018-11-26
Release date:2019-10-09
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Unravelling the receptor binding property of egg drop syndrome virus (EDSV) from the crystal structure of EDSV fiber head.
Int.J.Biol.Macromol., 139, 2019
5V58
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CRYSTAL STRUCTURE OF HUMAN PROLYL-TRNA SYNTHETASE IN COMPLEX WITH AZE-SA
Descriptor:Bifunctional glutamate/proline--tRNA ligase, 5'-O-{[(2S)-azetidine-2-carbonyl]sulfamoyl}adenosine, ZINC ION
Authors:Zhou, H., Song, Y., Schimmel, P.
Deposit date:2017-03-13
Release date:2018-01-10
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid.
Nat Commun, 8, 2017
5V59
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF HUMAN ALARS IN COMPLEX WITH AZE-SA
Descriptor:Alanine--tRNA ligase, cytoplasmic, 5'-O-{[(2S)-azetidine-2-carbonyl]sulfamoyl}adenosine
Authors:Zhou, H., Song, Y., Schimmel, P.
Deposit date:2017-03-13
Release date:2018-01-10
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid.
Nat Commun, 8, 2017
5XOR
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CRYSTAL STRUCTURE OF N-TERMINAL REPLICASE PROTEIN OF PORCINE CIRCOVIRUS TYPE 2
Descriptor:Rep protein
Authors:Song, Y., Peng, G.
Deposit date:2017-05-30
Release date:2018-07-04
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (2.699 Å)
Cite:Crystal Structure of the Dimerized N Terminus of Porcine Circovirus Type 2 Replicase Protein Reveals a Novel Antiviral Interface
J. Virol., 92, 2018
5YHX
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STRUCTURE OF LACTOCOCCUS LACTIS ZITR, WILD TYPE
Descriptor:Zinc transport transcriptional regulator, ZINC ION
Authors:Song, Y., Liu, H., Zhu, R., Yi, C., Chen, P.
Deposit date:2017-10-01
Release date:2017-12-06
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
5YHY
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STRUCTURE OF LACTOCOCCUS LACTIS ZITR, C30S MUTANT
Descriptor:Zinc transport transcriptional regulator, ZINC ION
Authors:Song, Y., Liu, H., Zhu, R., Yi, C., Chen, P.
Deposit date:2017-10-01
Release date:2017-12-06
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
5YHZ
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STRUCTURE OF LACTOCOCCUS LACTIS ZITR, E41A MUTANT
Descriptor:Zinc transport transcriptional regulator, ZINC ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Song, Y., Liu, H., Zhu, R., Yi, C., Chen, P.
Deposit date:2017-10-01
Release date:2017-12-06
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
5YI0
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STRUCTURE OF LACTOCOCCUS LACTIS ZITR, C30AH42A MUTANT
Descriptor:Zinc transport transcriptional regulator, ZINC ION
Authors:Song, Y., Liu, H., Zhu, R., Yi, C., Chen, P.
Deposit date:2017-10-01
Release date:2017-12-06
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
5YI1
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STRUCTURE OF LACTOCOCCUS LACTIS ZITR, C30AH42A MUTANT IN APO FORM
Descriptor:Zinc transport transcriptional regulator
Authors:Song, Y., Liu, H., Zhu, R., Yi, C., Chen, P.
Deposit date:2017-10-01
Release date:2017-12-06
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
5YI2
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STRUCTURE OF LACTOCOCCUS LACTIS ZITR, WILD TYPE IN COMPLEX WITH DNA
Descriptor:Zinc transport transcriptional regulator, DNA (5'-D(*TP*GP*TP*TP*AP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*A)-3'), ZINC ION
Authors:Song, Y., Liu, H., Zhu, R., Yi, C., Chen, P.
Deposit date:2017-10-01
Release date:2017-12-06
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
5YI3
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STRUCTURE OF LACTOCOCCUS LACTIS ZITR, C30S MUTANT IN COMPLEX WITH DNA
Descriptor:Zinc transport transcriptional regulator, DNA (5'-D(*TP*GP*TP*TP*AP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*A)-3'), ZINC ION
Authors:Song, Y., Liu, H., Zhu, R., Yi, C., Chen, P.
Deposit date:2017-10-01
Release date:2017-12-06
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Proc.Natl.Acad.Sci.USA, 114, 2017
5CVC
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STRUCTURE OF MAIZE SERINE RACEMASE
Descriptor:Serine racemase, MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Song, Y., Zou, L., Fan, J.
Deposit date:2015-07-26
Release date:2016-03-16
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystal structure of maize serine racemase with pyridoxal 5'-phosphate.
Acta Crystallogr.,Sect.F, 72, 2016
5VBL
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STRUCTURE OF APELIN RECEPTOR IN COMPLEX WITH AGONIST PEPTIDE
Descriptor:agonist peptide, Apelin receptor,Rubredoxin,Apelin receptor Chimera, ZINC ION, ...
Authors:Ma, Y., Yue, Y., Ma, Y., Zhang, Q., Zhou, Q., Song, Y., Shen, Y., Li, X., Ma, X., Li, C., Hanson, M.A., Han, G.W., Sickmier, E.A., Swaminath, G., Zhao, S., Stevems, R.C., Hu, L.A., Zhong, W., Zhang, M., Xu, F.
Deposit date:2017-03-29
Release date:2017-05-31
Last modified:2017-07-19
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Apelin Control of the Human Apelin Receptor
Structure, 25, 2017
5YEI
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MECHANISTIC INSIGHT INTO THE REGULATION OF PSEUDOMONAS AERUGINOSA ASPARTATE KINASE
Descriptor:Aspartokinase, THREONINE, LYSINE, ...
Authors:Li, C., Yang, M., Liu, L., Peng, C., Li, T., He, L., Song, Y., Zhu, Y., Bao, R.
Deposit date:2017-09-17
Release date:2018-08-29
Last modified:2019-09-11
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Mechanistic insights into the allosteric regulation of Pseudomonas aeruginosa aspartate kinase.
Biochem.J., 475, 2018
6MO0
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STRUCTURE OF DENGUE VIRUS PROTEASE WITH AN ALLOSTERIC INHIBITOR THAT BLOCKS REPLICATION
Descriptor:FLAVIVIRUS_NS2B/Peptidase S7, 1-(4-{3-[4-(furan-3-yl)phenyl]-5-[(piperidin-4-yl)methoxy]pyrazin-2-yl}phenyl)methanamine
Authors:Lin, Y.-L., Nie, S., Hua, Y., Wu, J., Wu, F., Huo, T., Yao, Y., Song, Y.
Deposit date:2018-10-03
Release date:2019-05-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease.
J. Am. Chem. Soc., 141, 2019
6MO1
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STRUCTURE OF DENGUE VIRUS PROTEASE WITH AN ALLOSTERIC INHIBITOR THAT BLOCKS REPLICATION
Descriptor:FLAVIVIRUS_NS2B/Peptidase S7, 5-[4-(aminomethyl)phenyl]-6-[4-(furan-3-yl)phenyl]-N-[(piperidin-4-yl)methyl]pyrazin-2-amine
Authors:Lin, Y.-L., Hua, Y., Nie, S., Wu, J., Wu, F., Huo, T., Yao, Y., Song, Y.
Deposit date:2018-10-03
Release date:2019-05-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease.
J.Am.Chem.Soc., 141, 2019
6MO2
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STRUCTURE OF DENGUE VIRUS PROTEASE WITH AN ALLOSTERIC INHIBITOR THAT BLOCKS REPLICATION
Descriptor:FLAVIVIRUS_NS2B/Peptidase S7, 1-(4-{5-[(piperidin-4-yl)methoxy]-3-[4-(1H-pyrazol-4-yl)phenyl]pyrazin-2-yl}phenyl)methanamine
Authors:Lin, Y.-L., Nie, S., Hua, Y., Wu, J., Wu, F., Huo, T., Yao, Y., Song, Y.
Deposit date:2018-10-03
Release date:2019-05-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease.
J.Am.Chem.Soc., 141, 2019
3SR4
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CRYSTAL STRUCTURE OF HUMAN DOT1L IN COMPLEX WITH A SELECTIVE INHIBITOR
Descriptor:Histone-lysine N-methyltransferase, H3 lysine-79 specific, (2S)-2-azanyl-4-[[(2S,3S,4R,5R)-5-[6-(methylamino)purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]butanoic acid, ...
Authors:Diao, J., Chen, P., Yao, Y., Prasad, B.V.V., Song, Y.
Deposit date:2011-07-06
Release date:2011-10-05
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Selective Inhibitors of Histone Methyltransferase DOT1L: Design, Synthesis, and Crystallographic Studies.
J.Am.Chem.Soc., 133, 2011
4I3K
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CRYSTAL STRUCTURE OF A METABOLIC REDUCTASE WITH 1-HYDROXY-6-(4-HYDROXYBENZYL)-4-METHYLPYRIDIN-2(1H)-ONE
Descriptor:Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ...
Authors:Zheng, B., Yao, Y., Liu, Z., Deng, L., Anglin, J.L., Jiang, H., Prasad, B.V.V., Song, Y.
Deposit date:2012-11-26
Release date:2013-05-22
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (3.3056 Å)
Cite:Crystallographic Investigation and Selective Inhibition of Mutant Isocitrate Dehydrogenase.
ACS Med Chem Lett, 4, 2013