Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
2JOO
DownloadVisualize
BU of 2joo by Molmil
The NMR Solution Structure of Recombinant RGD-hirudin
Descriptor: Hirudin variant-1
Authors:Song, X, Mo, W, Liu, X, Yan, X, Song, H, Dai, L.
Deposit date:2007-03-14
Release date:2008-03-18
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:The NMR solution structure of recombinant RGD-hirudin
Biochem.Biophys.Res.Commun., 360, 2007
8D0A
DownloadVisualize
BU of 8d0a by Molmil
Crystal structure of human USP30 in complex with a covalent inhibitor 829 and a Fab
Descriptor: Ubiquitin carboxyl-terminal hydrolase 30, ZINC ION, mouse anti-huUSP30 Fab heavy chain, ...
Authors:Song, X, Butler, J, Li, C, Zhang, K, Zhang, D, Hao, Y.
Deposit date:2022-05-25
Release date:2023-02-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:TBD
To Be Published
8D1T
DownloadVisualize
BU of 8d1t by Molmil
Crystal structure of human USP30 in complex with a covalent inhibitor 552 and a Fab
Descriptor: (1R,2R,4S,7E)-7-[amino(sulfanyl)methylidene]-2-{[(1P)-3-chloro-3'-(1-cyanocyclopropyl)[1,1'-biphenyl]-4-carbonyl]amino}-7-azabicyclo[2.2.1]heptan-7-ium, 1,2-ETHANEDIOL, Ubiquitin carboxyl-terminal hydrolase 30, ...
Authors:Song, X, Butler, J, Li, C, Zhang, K, Zhang, D, Hao, Y.
Deposit date:2022-05-27
Release date:2023-02-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:TBD
To Be Published
5UN1
DownloadVisualize
BU of 5un1 by Molmil
Crystal structure of GluN1/GluN2B delta-ATD NMDA receptor
Descriptor: (5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Song, X, Gouaux, E.
Deposit date:2017-01-30
Release date:2018-02-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Mechanism of NMDA receptor channel block by MK-801 and memantine.
Nature, 556, 2018
8SP6
DownloadVisualize
BU of 8sp6 by Molmil
COMPLEX STRUCTURE OF CDYL2 WITH AN ANTAGONIST
Descriptor: (1s,4s)-bicyclo[2.2.1]heptane, (5R0)FAL(MLZ)(5R5), Chromodomain Y-like protein 2, ...
Authors:Song, X, Beldar, S, Dong, A, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2023-05-02
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:COMPLEX STRUCTURE OF CDYL2 WITH AN ANTAGONIST
To be published
7SLZ
DownloadVisualize
BU of 7slz by Molmil
CRYSTAL STRUCTURE OF GID4 IN COMPLEX WITH BPF023596
Descriptor: Glucose-induced degradation protein 4 homolog, N-[(1s,4s)-4-(1H-benzimidazol-2-yl)cyclohexyl]-N~2~-[(1H-indol-2-yl)methyl]glycinamide
Authors:Song, X, Dong, A, Calabrese, M, Wang, F, Owen, D, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2021-10-25
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:CRYSTAL STRUCTURE OF GID4 IN COMPLEX WITH BPF023596
To Be Published
6JC3
DownloadVisualize
BU of 6jc3 by Molmil
The Cryo-EM structure of nucleoprotein-RNA complex of Newcastle disease virus
Descriptor: Nucleocapsid, polyU
Authors:Song, X, Shan, H, Zhu, Y, Ding, W, Ouyang, S, Shen, Q.T, Liu, Z.J.
Deposit date:2019-01-28
Release date:2019-08-07
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Self-capping of nucleoprotein filaments protects the Newcastle disease virus genome.
Elife, 8, 2019
4F7G
DownloadVisualize
BU of 4f7g by Molmil
Crystal structure of talin autoinhibition complex
Descriptor: Talin-1
Authors:Song, X, Qin, J, Ye, S, Zhang, R.
Deposit date:2012-05-16
Release date:2012-07-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion.
Cell Res., 22, 2012
8IA1
DownloadVisualize
BU of 8ia1 by Molmil
plastidial glycerol-3-phosphate acyltransferases (GPAT) from the green alga Myrmecia incisa
Descriptor: Glycerol-3-phosphate acyltransferase, chloroplastic
Authors:Song, X.
Deposit date:2023-02-07
Release date:2024-02-07
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Unique recognition of the microalgal plastidial glycerol-3-phosphate acyltransferase for acyl-ACP
To Be Published
6JN2
DownloadVisualize
BU of 6jn2 by Molmil
Crystal structure of the coiled-coil domains of human DOT1L in complex with AF10
Descriptor: Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein AF-10
Authors:Song, X, Wang, M, Yang, N, Xu, R.M.
Deposit date:2019-03-13
Release date:2019-09-18
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:A higher-order configuration of the heterodimeric DOT1L-AF10 coiled-coil domains potentiates their leukemogenenic activity.
Proc.Natl.Acad.Sci.USA, 116, 2019
7CYC
DownloadVisualize
BU of 7cyc by Molmil
Cryo-EM structures of Alphacoronavirus spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Song, X, Shi, Y, Ding, W, Liu, Z.J, Peng, G.
Deposit date:2020-09-03
Release date:2020-12-23
Last modified:2021-06-02
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Cryo-EM analysis of the HCoV-229E spike glycoprotein reveals dynamic prefusion conformational changes.
Nat Commun, 12, 2021
7CYD
DownloadVisualize
BU of 7cyd by Molmil
Cryo-EM structures of Alphacoronavirus spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Song, X, Shi, Y, Ding, W, Liu, Z.J, Peng, G.
Deposit date:2020-09-03
Release date:2020-12-23
Last modified:2021-06-02
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Cryo-EM analysis of the HCoV-229E spike glycoprotein reveals dynamic prefusion conformational changes.
Nat Commun, 12, 2021
6M1H
DownloadVisualize
BU of 6m1h by Molmil
CryoEM structure of human PAC1 receptor in complex with maxadilan
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Song, X, Wang, J, Zhang, D, Wang, H.W, Ma, Y.
Deposit date:2020-02-26
Release date:2020-03-11
Last modified:2020-05-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism.
Cell Res., 30, 2020
6M1I
DownloadVisualize
BU of 6m1i by Molmil
CryoEM structure of human PAC1 receptor in complex with PACAP38
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Song, X, Wang, J, Zhang, D, Wang, H.W, Ma, Y.
Deposit date:2020-02-26
Release date:2020-03-11
Last modified:2020-05-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism.
Cell Res., 30, 2020
4OUM
DownloadVisualize
BU of 4oum by Molmil
Crystal structure of human Caprin-2 C1q domain
Descriptor: CITRATE ANION, Caprin-2, ISOPROPYL ALCOHOL, ...
Authors:Song, X, Li, L.
Deposit date:2014-02-18
Release date:2014-10-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.491 Å)
Cite:Structural insights into the C1q domain of Caprin-2 in canonical Wnt signaling
J.Biol.Chem., 289, 2014
4OUS
DownloadVisualize
BU of 4ous by Molmil
Crystal structure of zebrafish Caprin-2 C1q domain
Descriptor: CALCIUM ION, Caprin-2
Authors:Song, X, Li, L.
Deposit date:2014-02-18
Release date:2014-10-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Structural insights into the C1q domain of Caprin-2 in canonical Wnt signaling
J.Biol.Chem., 289, 2014
4OUL
DownloadVisualize
BU of 4oul by Molmil
Crystal structure of human Caprin-2 C1q domain
Descriptor: CALCIUM ION, Caprin-2, GLYCEROL
Authors:Song, X, Li, L.
Deposit date:2014-02-17
Release date:2014-10-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:Structural insights into the C1q domain of Caprin-2 in canonical Wnt signaling
J.Biol.Chem., 289, 2014
8G2G
DownloadVisualize
BU of 8g2g by Molmil
Crystal structure of PRMT3 with compound YD1113
Descriptor: 5'-S-[2-(benzylcarbamamido)ethyl]-5'-thioadenosine, Protein arginine N-methyltransferase 3, SULFATE ION
Authors:Song, X, Dong, A, Arrowsmith, C.H, Edwards, A.M, Deng, Y, Huang, R, Min, J.
Deposit date:2023-02-03
Release date:2023-04-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors.
Acta Pharm Sin B, 13, 2023
8G2F
DownloadVisualize
BU of 8g2f by Molmil
Crystal Structure of PRMT3 with Compound II710
Descriptor: 5'-S-[3-(N'-benzylcarbamimidamido)propyl]-5'-thioadenosine, Protein arginine N-methyltransferase 3
Authors:Song, X, Dong, A, Deng, Y, Huang, R, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2023-02-03
Release date:2023-05-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors.
Acta Pharm Sin B, 13, 2023
8G2H
DownloadVisualize
BU of 8g2h by Molmil
Crystal Structure of PRMT4 with Compound YD1113
Descriptor: 5'-S-[2-(benzylcarbamamido)ethyl]-5'-thioadenosine, GLYCEROL, Histone-arginine methyltransferase CARM1, ...
Authors:Song, X, Dong, A, Deng, Y, Huang, R, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2023-02-03
Release date:2023-12-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors.
Acta Pharm Sin B, 13, 2023
8G2I
DownloadVisualize
BU of 8g2i by Molmil
Crystal Structure of PRMT4 with Compound YD1290
Descriptor: 5'-([2-(benzylcarbamamido)ethyl]{3-[N'-(3-bromophenyl)carbamimidamido]propyl}amino)-5'-deoxyadenosine, Histone-arginine methyltransferase CARM1, UNKNOWN ATOM OR ION
Authors:Song, X, Dong, A, Deng, Y, Huang, R, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2023-02-03
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors.
Acta Pharm Sin B, 13, 2023
2UZT
DownloadVisualize
BU of 2uzt by Molmil
PKA structures of AKT, indazole-pyridine inhibitors
Descriptor: (2S)-1-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}-3-PHENYLPROPAN-2-AMINE, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, CAMP-DEPENDENT PROTEIN KINASE, ...
Authors:Zhu, G.D, Gandhi, V.B, Gong, J, Thomas, S, Woods, K.W, Song, X, Li, T, Diebold, R.B, Luo, Y, Liu, X, Guan, R, Klinghofer, V, Johnson, E.F, Bouska, J, Olson, A, Marsh, K.C, Stoll, V.S, Mamo, M, Polakowski, J, Campbell, T.J, Penning, T.D, Li, Q, Rosenberg, S.H, Giranda, V.L.
Deposit date:2007-05-01
Release date:2007-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Syntheses of Potent, Selective, and Orally Bioavailable Indazole-Pyridine Series of Protein Kinase B/Akt Inhibitors with Reduced Hypotension.
J.Med.Chem., 50, 2007
2UZU
DownloadVisualize
BU of 2uzu by Molmil
PKA structures of indazole-pyridine series of AKT inhibitors
Descriptor: (2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, CAMP-DEPENDENT PROTEIN KINASE, ...
Authors:Zhu, G.D, Gandhi, V.B, Gong, J, Thomas, S, Woods, K.W, Song, X, Li, T, Diebold, R.B, Luo, Y, Liu, X, Guan, R, Klinghofer, V, Johnson, E.F, Bouska, J, Olson, A, Marsh, K.C, Stoll, V.S, Mamo, M, Polakowski, J, Campbell, T.J, Penning, T.D, Li, Q, Rosenberg, S.H, Giranda, V.L.
Deposit date:2007-05-01
Release date:2007-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Syntheses of Potent, Selective, and Orally Bioavailable Indazole-Pyridine Series of Protein Kinase B/Akt Inhibitors with Reduced Hypotension.
J.Med.Chem., 50, 2007
2UZV
DownloadVisualize
BU of 2uzv by Molmil
PKA structures of indazole-pyridine series of AKT inhibitors
Descriptor: (2S)-1-[3-(CYCLOHEXYLMETHOXY)PHENYL]-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA,, CAMP-DEPENDENT PROTEIN KINASE, ...
Authors:Zhu, G.D, Gandhi, V.B, Gong, J, Thomas, S, Woods, K.W, Song, X, Li, T, Diebold, R.B, Luo, Y, Liu, X, Guan, R, Klinghofer, V, Johnson, E.F, Bouska, J, Olson, A, Marsh, K.C, Stoll, V.S, Mamo, M, Polakowski, J, Campbell, T.J, Penning, T.D, Li, Q, Rosenberg, S.H, Giranda, V.L.
Deposit date:2007-05-01
Release date:2007-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Syntheses of Potent, Selective, and Orally Bioavailable Indazole-Pyridine Series of Protein Kinase B/Akt Inhibitors with Reduced Hypotension.
J.Med.Chem., 50, 2007
2UZW
DownloadVisualize
BU of 2uzw by Molmil
PKA structures of indazole-pyridine series of AKT inhibitors
Descriptor: 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.] PYRAZOLE, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, CAMP-DEPENDENT PROTEIN KINASE, ...
Authors:Zhu, G.D, Gandhi, V.B, Gong, J, Thomas, S, Woods, K.W, Song, X, Li, T, Diebold, R.B, Luo, Y, Liu, X, Guan, R, Klinghofer, V, Johnson, E.F, Bouska, J, Olson, A, Marsh, K.C, Stoll, V.S, Mamo, M, Polakowski, J, Campbell, T.J, Penning, T.D, Li, Q, Rosenberg, S.H, Giranda, V.L.
Deposit date:2007-05-01
Release date:2007-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Syntheses of Potent, Selective, and Orally Bioavailable Indazole-Pyridine Series of Protein Kinase B/Akt Inhibitors with Reduced Hypotension.
J.Med.Chem., 50, 2007

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon