7V8V
 
 | | Crystal structure of PsEst3 S128A mutant | | Descriptor: | esterase | | Authors: | Son, J, Kim, H, Kim, H.W. | | Deposit date: | 2021-08-23 | | Release date: | 2022-08-31 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and biochemical insights into PsEst3, a new GHSR-type esterase obtained from Paenibacillus sp. R4.
Iucrj, 10, 2023
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7V8W
 | | Crystal structure of PsEst3 S128A variant complexed with malonate | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, MALONIC ACID, ... | | Authors: | Son, J, Kim, H, Kim, H.W. | | Deposit date: | 2021-08-23 | | Release date: | 2022-08-31 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural and biochemical insights into PsEst3, a new GHSR-type esterase obtained from Paenibacillus sp. R4.
Iucrj, 10, 2023
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7V8X
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7V8U
 | | Crystal structure of PsEst3 wild-type | | Descriptor: | Esterase, NITROBENZENE, SULFATE ION | | Authors: | Son, J, Kim, H, Kim, H.W. | | Deposit date: | 2021-08-23 | | Release date: | 2022-08-31 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural and biochemical insights into PsEst3, a new GHSR-type esterase obtained from Paenibacillus sp. R4.
Iucrj, 10, 2023
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5CZY
 | | Crystal structure of LegAS4 | | Descriptor: | GLYCEROL, Legionella effector LegAS4, S-ADENOSYLMETHIONINE | | Authors: | Son, J, Hwang, K.Y, Lee, W.C. | | Deposit date: | 2015-08-01 | | Release date: | 2015-09-23 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of Legionella pneumophila type IV secretion system effector LegAS4
Biochem.Biophys.Res.Commun., 465, 2015
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5ZFX
 | | Crystal Structure of Triosephosphate isomerase from Opisthorchis viverrini | | Descriptor: | MAGNESIUM ION, Triosephosphate isomerase | | Authors: | Son, J, Kim, S, Kim, S.E, Lee, H, Lee, M.R, Hwang, K.Y. | | Deposit date: | 2018-03-07 | | Release date: | 2018-10-24 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.751 Å) | | Cite: | Structural Analysis of an Epitope Candidate of Triosephosphate Isomerase in Opisthorchis viverrini.
Sci Rep, 8, 2018
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5ZG5
 | | Crystal Structure of Triosephosphate isomerase SADsubAAA mutant from Opisthorchis viverrini | | Descriptor: | Triosephosphate isomerase | | Authors: | Son, J, Kim, S, Kim, S.E, Lee, H, Lee, M.R, Hwang, K.Y. | | Deposit date: | 2018-03-07 | | Release date: | 2018-10-24 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.597 Å) | | Cite: | Structural Analysis of an Epitope Candidate of Triosephosphate Isomerase in Opisthorchis viverrini.
Sci Rep, 8, 2018
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5ZGA
 | | Crystal Structure of Triosephosphate isomerase SAD deletion and N115A mutant from Opisthorchis viverrini | | Descriptor: | Triosephosphate isomerase | | Authors: | Son, J, Kim, S, Kim, S.E, Lee, H, Lee, M.R, Hwang, K.Y. | | Deposit date: | 2018-03-08 | | Release date: | 2018-10-24 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.793 Å) | | Cite: | Structural Analysis of an Epitope Candidate of Triosephosphate Isomerase in Opisthorchis viverrini.
Sci Rep, 8, 2018
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5ZG4
 | | Crystal Structure of Triosephosphate isomerase SAD deletion mutant from Opisthorchis viverrini | | Descriptor: | Triosephosphate isomerase | | Authors: | Son, J, Kim, S, Kim, S.E, Lee, H, Lee, M.R, Hwang, K.Y. | | Deposit date: | 2018-03-07 | | Release date: | 2018-10-24 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.746 Å) | | Cite: | Structural Analysis of an Epitope Candidate of Triosephosphate Isomerase in Opisthorchis viverrini.
Sci Rep, 8, 2018
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7L9C
 | | Receiver Domain of RssB | | Descriptor: | Regulator of RpoS | | Authors: | Deaconescu, A.M, Son, J, Schwartz, J. | | Deposit date: | 2021-01-03 | | Release date: | 2021-04-07 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Phospho-dependent signaling during the general stress response by the atypical response regulator and ClpXP adaptor RssB.
Protein Sci., 30, 2021
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7LCM
 | | Receiver Domain of RssB bound to beryllofluoride | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Regulator of RpoS | | Authors: | Deaconescu, A.M, Schwartz, J, Son, J. | | Deposit date: | 2021-01-11 | | Release date: | 2021-04-07 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Phospho-dependent signaling during the general stress response by the atypical response regulator and ClpXP adaptor RssB.
Protein Sci., 30, 2021
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7Y28
 | | Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1 | | Descriptor: | 1-[6-(3-fluorophenyl)benzimidazol-1-yl]-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ... | | Authors: | Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y. | | Deposit date: | 2022-06-09 | | Release date: | 2023-07-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1.
Embo Mol Med, 15, 2023
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7Y3S
 | | Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1 | | Descriptor: | 1-(6-bromanyl-7-methyl-imidazo[4,5-b]pyridin-3-yl)-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ... | | Authors: | Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y. | | Deposit date: | 2022-06-12 | | Release date: | 2023-07-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1.
Embo Mol Med, 15, 2023
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7Y1W
 | | Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1 | | Descriptor: | (2R,3S)-2-[3-[4,5-bis(chloranyl)benzimidazol-1-yl]propyl]piperidin-3-ol, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ... | | Authors: | Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y. | | Deposit date: | 2022-06-09 | | Release date: | 2023-07-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1.
Embo Mol Med, 15, 2023
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7Y1H
 | | Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1 | | Descriptor: | 1-(5-chloranyl-4-methyl-benzimidazol-1-yl)-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ... | | Authors: | Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y. | | Deposit date: | 2022-06-08 | | Release date: | 2023-07-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1.
Embo Mol Med, 15, 2023
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7E3Q
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7E3R
 | | Crystal structure of TrmL from Vibrio vulnificus | | Descriptor: | tRNA (cytidine(34)-2'-O)-methyltransferase | | Authors: | Kim, J, Son, J. | | Deposit date: | 2021-02-09 | | Release date: | 2022-02-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Crystal structure of tRNA mehtyltransferase TrmL from Vibrio vulnificus
To be published
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7E3T
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7E3S
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5EY2
 | | Crystal structure of CodY from Bacillus cereus | | Descriptor: | GTP-sensing transcriptional pleiotropic repressor CodY | | Authors: | Han, A, Lee, W.C, Son, J, Kim, S.H, Hwang, K.Y. | | Deposit date: | 2015-11-24 | | Release date: | 2016-09-14 | | Last modified: | 2020-02-19 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The structure of the pleiotropic transcription regulator CodY provides insight into its GTP-sensing mechanism
Nucleic Acids Res., 44, 2016
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5FA9
 | | Bifunctional Methionine Sulfoxide Reductase AB (MsrAB) from Treponema denticola | | Descriptor: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Peptide methionine sulfoxide reductase MsrA | | Authors: | Han, A, Son, J, Kim, H.-Y, Hwang, K.Y. | | Deposit date: | 2015-12-11 | | Release date: | 2016-09-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.302 Å) | | Cite: | Essential Role of the Linker Region in the Higher Catalytic Efficiency of a Bifunctional MsrA-MsrB Fusion Protein
Biochemistry, 55, 2016
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6KIE
 | | Crystal structure of human leucyl-tRNA synthetase, Leu-AMS-bound form | | Descriptor: | 5'-O-(L-leucylsulfamoyl)adenosine, LEUCINE, Leucine--tRNA ligase, ... | | Authors: | Kim, S, Son, J, Kim, S, Hwang, K.Y. | | Deposit date: | 2019-07-18 | | Release date: | 2021-01-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation.
Cell Rep, 35, 2021
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6KID
 | | Crystal structure of human leucyl-tRNA synthetase, ATP-bound form | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, LEUCINE, Leucine--tRNA ligase, ... | | Authors: | Kim, S, Son, J, Kim, S, Hwang, K.Y. | | Deposit date: | 2019-07-18 | | Release date: | 2021-01-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation.
Cell Rep, 35, 2021
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6KQY
 | | Crystal structure of human leucyl-tRNA synthetase, Leucine-bound form | | Descriptor: | LEUCINE, Leucine--tRNA ligase, cytoplasmic, ... | | Authors: | Kim, S, Son, J, Kim, S, Hwang, K.Y. | | Deposit date: | 2019-08-20 | | Release date: | 2021-01-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation.
Cell Rep, 35, 2021
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6KR7
 | | Crystal structure of methylated human leucyl-tRNA synthetase, Leu-AMS-bound form | | Descriptor: | 5'-O-(L-leucylsulfamoyl)adenosine, LEUCINE, Leucine--tRNA ligase, ... | | Authors: | Kim, S, Son, J, Kim, S, Hwang, K.Y. | | Deposit date: | 2019-08-21 | | Release date: | 2021-01-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation.
Cell Rep, 35, 2021
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