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1A0L
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BU of 1a0l by Molmil
HUMAN BETA-TRYPTASE: A RING-LIKE TETRAMER WITH ACTIVE SITES FACING A CENTRAL PORE
Descriptor: (2S)-3-(4-carbamimidoylphenyl)-2-hydroxypropanoic acid, BETA-TRYPTASE
Authors:Pereira, P.J.B, Bergner, A, Macedo-Ribeiro, S, Huber, R, Matschiner, G, Fritz, H, Sommerhoff, C.P, Bode, W.
Deposit date:1997-12-03
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.
Nature, 392, 1998
1ZLI
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BU of 1zli by Molmil
Crystal structure of the tick carboxypeptidase inhibitor in complex with human carboxypeptidase B
Descriptor: Carboxypeptidase B, ZINC ION, carboxypeptidase inhibitor
Authors:Arolas, J.L, Popowicz, G.M, Lorenzo, J, Sommerhoff, C.P, Huber, R, Aviles, F.X, Holak, T.A.
Deposit date:2005-05-06
Release date:2005-07-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode
J.Mol.Biol., 350, 2005
1ZLH
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BU of 1zlh by Molmil
Crystal structure of the tick carboxypeptidase inhibitor in complex with bovine carboxypeptidase A
Descriptor: Carboxypeptidase A1, ZINC ION, carboxypeptidase inhibitor
Authors:Arolas, J.L, Popowicz, G.M, Lorenzo, J, Sommerhoff, C.P, Huber, R, Aviles, F.X, Holak, T.A.
Deposit date:2005-05-06
Release date:2005-07-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode
J.Mol.Biol., 350, 2005
1LTO
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BU of 1lto by Molmil
Human alpha1-tryptase
Descriptor: alpha tryptase I
Authors:Marquardt, U, Zettl, F, Huber, R, Bode, W, Sommerhoff, C.P.
Deposit date:2002-05-20
Release date:2003-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structure of Human alpha1-Tryptase Reveals a Blocked Substrate-binding Region
J.MOL.BIOL., 321, 2002
1LDT
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BU of 1ldt by Molmil
COMPLEX OF LEECH-DERIVED TRYPTASE INHIBITOR WITH PORCINE TRYPSIN
Descriptor: CALCIUM ION, TRYPSIN, TRYPTASE INHIBITOR
Authors:Stubbs, M.T.
Deposit date:1997-05-15
Release date:1998-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The three-dimensional structure of recombinant leech-derived tryptase inhibitor in complex with trypsin. Implications for the structure of human mast cell tryptase and its inhibition.
J.Biol.Chem., 272, 1997
1BX7
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BU of 1bx7 by Molmil
HIRUSTASIN FROM HIRUDO MEDICINALIS AT 1.2 ANGSTROMS
Descriptor: HIRUSTASIN, SULFATE ION
Authors:Uson, I, Sheldrick, G.M, De La Fortelle, E, Bricogne, G, Di Marco, S, Priestle, J.P, Gruetter, M.G, Mittl, P.R.E.
Deposit date:1998-10-14
Release date:1999-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The 1.2 A crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors.
Structure Fold.Des., 7, 1999
1BX8
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BU of 1bx8 by Molmil
HIRUSTASIN FROM HIRUDO MEDICINALIS AT 1.4 ANGSTROMS
Descriptor: HIRUSTASIN, SULFATE ION
Authors:Uson, I, Sheldrick, G.M, De La Fortelle, E, Bricogne, G, Di Marco, S, Priestle, J.P, Gruetter, M.G, Mittl, P.R.E.
Deposit date:1998-10-14
Release date:1999-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The 1.2 A crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors.
Structure Fold.Des., 7, 1999
1AN1
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BU of 1an1 by Molmil
LEECH-DERIVED TRYPTASE INHIBITOR/TRYPSIN COMPLEX
Descriptor: CALCIUM ION, TRYPSIN, TRYPTASE INHIBITOR
Authors:Priestle, J.P, Di Marco, S.
Deposit date:1997-06-26
Release date:1998-07-01
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.
Structure, 5, 1997
2LFL
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BU of 2lfl by Molmil
NMR solution structure of the intermediate IIIb of TdPI-short
Descriptor: Tryptase inhibitor
Authors:Bronsoms, S, Pantoja-Uceda, D, Gabrijelcic-Geiger, D, Sanglas, L, Aviles, F, Santoro, J, Sommerhoff, C, Arolas, J.
Deposit date:2011-07-06
Release date:2011-11-09
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Oxidative folding and structural analyses of a kunitz-related inhibitor and its disulfide intermediates: functional implications.
J.Mol.Biol., 414, 2011
2LFK
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BU of 2lfk by Molmil
NMR solution structure of native TdPI-short
Descriptor: Tryptase inhibitor
Authors:Bronsoms, S, Pantoja-Uceda, D, Gabrijelcic-Geiger, D, Sanglas, L, Aviles, F, Santoro, J, Sommerhoff, C, Arolas, J.
Deposit date:2011-07-06
Release date:2011-11-09
Last modified:2023-12-06
Method:SOLUTION NMR
Cite:Oxidative folding and structural analyses of a kunitz-related inhibitor and its disulfide intermediates: functional implications.
J.Mol.Biol., 414, 2011
2KMO
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BU of 2kmo by Molmil
Solution structure of native Leech-derived tryptase inhibitor, LDTI
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMR
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BU of 2kmr by Molmil
Solution structure of intermediate IIc of Leech-derived tryptase inhibitor, LDTI.
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMP
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BU of 2kmp by Molmil
Solution structure of intermeidate IIa of Leeck-derived tryptase inhibitor, LDTI.
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMQ
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BU of 2kmq by Molmil
Solution structure of intermediate IIb of Leech-derived tryptase inhibitor, LDTI.
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
1TFX
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BU of 1tfx by Molmil
COMPLEX OF THE SECOND KUNITZ DOMAIN OF TISSUE FACTOR PATHWAY INHIBITOR WITH PORCINE TRYPSIN
Descriptor: CALCIUM ION, TISSUE FACTOR PATHWAY INHIBITOR, TRYPSIN
Authors:Stubbs, M.T, Huber, R.
Deposit date:1997-01-21
Release date:1998-01-21
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa.
J.Mol.Biol., 269, 1997
2IT8
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BU of 2it8 by Molmil
Solution structure of a linear analog of the cyclic squash trypsin inhibitor MCoTI-II
Descriptor: Trypsin inhibitor 2
Authors:Avrutina, O, Chiche, L, Diederichsen, U, Heitz, A, Kolmar, H.
Deposit date:2006-10-19
Release date:2007-10-02
Last modified:2014-04-02
Method:SOLUTION NMR
Cite:Knottin cyclization: Structure and stability of cyclic and linear squash inhibitors do not differ significantly
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217705

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