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8UPT
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BU of 8upt by Molmil
Candidatus Methanomethylophilus alvus tRNAPyl in A-site of ribosome
Descriptor: RNA (71-MER)
Authors:Krahn, N, Zhang, J, Melnikov, S.V, Tharp, J.M, Villa, A, Patel, A, Howard, R.J, Gabir, H, Patel, T.R, Stetefeld, J, Puglisi, J, Soll, D.
Deposit date:2023-10-23
Release date:2024-01-10
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:tRNA shape is an identity element for an archaeal pyrrolysyl-tRNA synthetase from the human gut.
Nucleic Acids Res., 52, 2024
4TQD
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BU of 4tqd by Molmil
Crystal Structure of the C-terminal domain of IFRS bound with 3-iodo-L-Phe and ATP
Descriptor: 1,2-ETHANEDIOL, 3-iodo-L-phenylalanine, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Nakamura, A, O'Donoghue, P, Soll, D.
Deposit date:2014-06-11
Release date:2014-11-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1429 Å)
Cite:Polyspecific pyrrolysyl-tRNA synthetases from directed evolution.
Proc.Natl.Acad.Sci.USA, 111, 2014
4TQF
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BU of 4tqf by Molmil
Crystal Structure of the C-terminal domain of IFRS bound with 2-(5-bromothienyl)-L-Ala and ATP
Descriptor: 1,2-ETHANEDIOL, 3-(5-bromothiophen-2-yl)-L-alanine, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Nakamura, A, O'Donoghue, P, Soll, D.
Deposit date:2014-06-11
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7143 Å)
Cite:Polyspecific pyrrolysyl-tRNA synthetases from directed evolution.
Proc.Natl.Acad.Sci.USA, 111, 2014
6N9F
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BU of 6n9f by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic ACCA-DPhe and bound to mRNA and P-site tRNA at 3.7A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S19, ...
Authors:Melnikov, S.V, Khabibullina, N.F, Mairhofer, E, Vargas-Rodriguez, O, Reynolds, N.M, Micura, R, Soll, D, Polikanov, Y.S.
Deposit date:2018-12-03
Release date:2018-12-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site.
Nucleic Acids Res., 47, 2019
6N9E
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BU of 6n9e by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic CC-Pmn and bound to mRNA and P-site tRNA at 3.7A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S19, ...
Authors:Melnikov, S.V, Khabibullina, N.F, Mairhofer, E, Vargas-Rodriguez, O, Reynolds, N.M, Micura, R, Soll, D, Polikanov, Y.S.
Deposit date:2018-12-03
Release date:2018-12-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site.
Nucleic Acids Res., 47, 2019
4ZIB
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BU of 4zib by Molmil
Crystal Structure of the C-terminal domain of PylRS mutant bound with 3-benzothienyl-l-alanine and ATP
Descriptor: 1,2-ETHANEDIOL, 3-(1-benzothiophen-3-yl)-L-alanine, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Nakamura, A, Guo, L.T, Wang, Y.S, Soll, D.
Deposit date:2015-04-28
Release date:2016-03-02
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.054 Å)
Cite:Probing the active site tryptophan of Staphylococcus aureus thioredoxin with an analog.
Nucleic Acids Res., 43, 2015
4EO4
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BU of 4eo4 by Molmil
Crystal structure of the yeast mitochondrial threonyl-tRNA synthetase (MST1) in complex with seryl sulfamoyl adenylate
Descriptor: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, Threonine--tRNA ligase, mitochondrial, ...
Authors:Peterson, K.M, Ling, J, Simonovic, I, Soll, D, Simonovic, M.
Deposit date:2012-04-13
Release date:2012-07-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:The mechanism of pre-transfer editing in yeast mitochondrial threonyl-tRNA synthetase.
J.Biol.Chem., 287, 2012
1IRX
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BU of 1irx by Molmil
Crystal structure of class I lysyl-tRNA synthetase
Descriptor: ZINC ION, lysyl-tRNA synthetase
Authors:Nureki, O, Terada, T, Ishitani, R, Ambrogelly, A, Ibba, M, Soll, D, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2001-10-25
Release date:2002-04-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Functional convergence of two lysyl-tRNA synthetases with unrelated topologies.
Nat.Struct.Biol., 9, 2002
2CJ9
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BU of 2cj9 by Molmil
Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with an analog of seryladenylate
Descriptor: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, CHLORIDE ION, SERYL-TRNA SYNTHETASE, ...
Authors:Bilokapic, S, Maier, T, Ahel, D, Gruic-Sovulj, I, Soll, D, Weygand-Durasevic, I, Ban, N.
Deposit date:2006-03-29
Release date:2006-06-26
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition
Embo J., 25, 2006
2CJA
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BU of 2cja by Molmil
Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Bilokapic, S, Maier, T, Ahel, D, Gruic-Sovulj, I, Soll, D, Weygand-Durasevic, I, Ban, N.
Deposit date:2006-03-30
Release date:2006-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition
Embo J., 25, 2006
2CIM
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BU of 2cim by Molmil
Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase
Descriptor: CHLORIDE ION, PLATINUM (II) ION, SERYL-TRNA SYNTHETASE, ...
Authors:Bilokapic, S, Maier, T, Ahel, D, Gruic-Sovulj, I, Soll, D, Weygand-Durasevic, I, Ban, N.
Deposit date:2006-03-24
Release date:2006-06-26
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition
Embo J., 25, 2006
2CJB
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BU of 2cjb by Molmil
Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with serine
Descriptor: CHLORIDE ION, SERINE, SERYL-TRNA SYNTHETASE, ...
Authors:Bilokapic, S, Maier, T, Ahel, D, Gruic-Sovulj, I, Soll, D, Weygand-Durasevic, I, Ban, N.
Deposit date:2006-03-30
Release date:2006-06-26
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition
Embo J., 25, 2006
4DWQ
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BU of 4dwq by Molmil
RNA ligase RtcB-GMP/Mn(2+) complex
Descriptor: GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE, MALONATE ION, ...
Authors:Okada, C, Xia, S, Englert, M, Yao, M, Soll, D, Wang, J.
Deposit date:2012-02-26
Release date:2012-09-05
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OH.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DWR
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BU of 4dwr by Molmil
RNA ligase RtcB/Mn2+ complex
Descriptor: MANGANESE (II) ION, SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ...
Authors:Xia, S, Englert, M, Soll, D, Wang, J.
Deposit date:2012-02-26
Release date:2012-09-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OH.
Proc.Natl.Acad.Sci.USA, 109, 2012
4Y4O
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BU of 4y4o by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome with rRNA modifications and bound to protein Y (YfiA) at 2.3A resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
Authors:Polikanov, Y.S, Melnikov, S.V, Soll, D, Steitz, T.A.
Deposit date:2015-02-10
Release date:2015-03-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.
Nat.Struct.Mol.Biol., 22, 2015
4Y4P
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BU of 4y4p by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome with rRNA modifications and bound to mRNA and A-, P- and E-site tRNAs at 2.5A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Polikanov, Y.S, Melnikov, S.V, Soll, D, Steitz, T.A.
Deposit date:2015-02-10
Release date:2015-03-18
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.
Nat.Struct.Mol.Biol., 22, 2015
5UD5
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BU of 5ud5 by Molmil
Crystal structure of the tRNA binding domain of Pyrrolysyl-tRNA synthetase bound to tRNA(Pyl)
Descriptor: Pyrrolysine--tRNA ligase, RNA (70-MER), ZINC ION
Authors:Suzuki, T, Soll, D.
Deposit date:2016-12-23
Release date:2017-10-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.347 Å)
Cite:Crystal structures reveal an elusive functional domain of pyrrolysyl-tRNA synthetase.
Nat. Chem. Biol., 13, 2017
5V6X
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BU of 5v6x by Molmil
Crystal structure of the tRNA binding domain of Pyrrolysyl-tRNA synthetase mutant (32A NTD) bound to tRNA(Pyl)
Descriptor: Pyrrolysine--tRNA ligase, RNA (70-MER), ZINC ION
Authors:Suzuki, T, Soll, D.
Deposit date:2017-03-17
Release date:2017-10-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Crystal structures reveal an elusive functional domain of pyrrolysyl-tRNA synthetase.
Nat. Chem. Biol., 13, 2017
3A4N
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BU of 3a4n by Molmil
Crystal structure of archaeal O-phosphoseryl-tRNA(Sec) kinase
Descriptor: 1,2-ETHANEDIOL, IODIDE ION, L-seryl-tRNA(Sec) kinase, ...
Authors:Araiso, Y, Ishitani, R, Soll, D, Nureki, O.
Deposit date:2009-07-10
Release date:2009-10-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of a tRNA-dependent kinase essential for selenocysteine decoding
Proc.Natl.Acad.Sci.USA, 106, 2009
3A4L
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BU of 3a4l by Molmil
Crystal structure of archaeal O-phosphoseryl-tRNA(Sec) kinase
Descriptor: 1,2-ETHANEDIOL, IODIDE ION, L-seryl-tRNA(Sec) kinase, ...
Authors:Araiso, Y, Ishitani, R, Soll, D, Nureki, O.
Deposit date:2009-07-10
Release date:2009-10-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of a tRNA-dependent kinase essential for selenocysteine decoding
Proc.Natl.Acad.Sci.USA, 106, 2009
5J4C
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BU of 5j4c by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with cisplatin (soaked) and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Melnikov, S.V, Soll, D, Steitz, T.A, Polikanov, Y.S.
Deposit date:2016-03-31
Release date:2016-04-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome.
Nucleic Acids Res., 44, 2016
5J4B
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BU of 5j4b by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with cisplatin (co-crystallized) and bound to mRNA and A-, P- and E-site tRNAs at 2.6A resolution
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Melnikov, S.V, Soll, D, Steitz, T.A, Polikanov, Y.S.
Deposit date:2016-03-31
Release date:2016-04-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome.
Nucleic Acids Res., 44, 2016
2Z67
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BU of 2z67 by Molmil
Crystal structure of archaeal O-phosphoseryl-tRNA(Sec) selenium transferase (SepSecS)
Descriptor: O-phosphoseryl-tRNA(Sec) selenium transferase, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
Authors:Araiso, Y, Ishitani, R, Pailouer, S, Oshikane, H, Domae, N, Soll, D, Nureki, O.
Deposit date:2007-07-23
Release date:2008-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into RNA-dependent eukaryal and archaeal selenocysteine formation.
Nucleic Acids Res., 36, 2008
2ZNI
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BU of 2zni by Molmil
Crystal structure of Pyrrolysyl-tRNA synthetase-tRNA(Pyl) complex from Desulfitobacterium hafniense
Descriptor: CALCIUM ION, Pyrrolysyl-tRNA synthetase, bacterial tRNA
Authors:Nozawa, K, Araiso, Y, Soll, D, Ishitani, R, Nureki, O.
Deposit date:2008-04-25
Release date:2008-12-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular basis of orthogonality
Nature, 457, 2009
2ZNJ
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BU of 2znj by Molmil
Crystal structure of Pyrrolysyl-tRNA synthetase from Desulfitobacterium hafniense
Descriptor: Putative uncharacterized protein
Authors:Nozawa, K, Araiso, Y, Soll, D, Ishitani, R, Nureki, O.
Deposit date:2008-04-25
Release date:2008-12-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular basis of orthogonality
Nature, 457, 2009

 

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