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6N1R
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BU of 6n1r by Molmil
Tetrahedral oligomeric complex of GyrA N-terminal fragment, solved by cryoEM in tetrahedral symmetry
Descriptor: DNA gyrase subunit A
Authors:Soczek, K.M, Grant, T, Rosenthal, P.B, Mondragon, A.
Deposit date:2018-11-10
Release date:2018-12-05
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:CryoEM structures of open dimers of Gyrase A in complex with DNA illuminate mechanism of strand passage.
Elife, 7, 2018
6N1P
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BU of 6n1p by Molmil
Dihedral oligomeric complex of GyrA N-terminal fragment with DNA, solved by cryoEM in C2 symmetry
Descriptor: DNA (44-MER), DNA gyrase subunit A
Authors:Soczek, K.M, Grant, T, Rosenthal, P.B, Mondragon, A.
Deposit date:2018-11-10
Release date:2018-12-05
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (6.35 Å)
Cite:CryoEM structures of open dimers of Gyrase A in complex with DNA illuminate mechanism of strand passage.
Elife, 7, 2018
6N1Q
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BU of 6n1q by Molmil
Dihedral oligomeric complex of GyrA N-terminal fragment, solved by cryoEM in D2 symmetry
Descriptor: DNA gyrase subunit A
Authors:Soczek, K.M, Grant, T, Rosenthal, P.B, Mondragon, A.
Deposit date:2018-11-10
Release date:2018-12-05
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (5.16 Å)
Cite:CryoEM structures of open dimers of Gyrase A in complex with DNA illuminate mechanism of strand passage.
Elife, 7, 2018
8FYA
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BU of 8fya by Molmil
Cryo-EM structure of Cas1:Cas2-DEDDh:PAM-containing prespacer complex
Descriptor: Cas1, Cas2-DEDDh, DNA (28-MER), ...
Authors:Skopintsev, P, Tuck, O.T, Soczek, K.M, Doudna, J.
Deposit date:2023-01-25
Release date:2023-05-03
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Genome expansion by a CRISPR trimmer-integrase.
Nature, 618, 2023
8FYC
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BU of 8fyc by Molmil
Cryo-EM structure of Cas1:Cas2-DEDDh:half-site integration complex linear CRISPR repeat conformation
Descriptor: Cas1, Cas2-DEDDh, DEDDh, ...
Authors:Skopintsev, P, Tuck, O.T, Soczek, K.M, Doudna, J.
Deposit date:2023-01-25
Release date:2023-05-03
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Genome expansion by a CRISPR trimmer-integrase.
Nature, 618, 2023
8FYD
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BU of 8fyd by Molmil
Cryo-EM structure of Cas1:Cas2-DEDDh:half-site integration complex bent CRISPR repeat conformation
Descriptor: Cas1, Cas2-DEDDh, DNA (13-MER), ...
Authors:Skopintsev, P, Tuck, O.T, Soczek, K.M, Doudna, J.
Deposit date:2023-01-25
Release date:2023-05-03
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Genome expansion by a CRISPR trimmer-integrase.
Nature, 618, 2023
8FY9
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BU of 8fy9 by Molmil
Cryo-EM structure of Cas1:Cas2-DEDDh:PAM-deficient prespacer complex
Descriptor: Cas1, Cas2-DEDDh, DNA (28-MER)
Authors:Skopintsev, P, Tuck, O.T, Soczek, K.M, Doudna, J.
Deposit date:2023-01-25
Release date:2023-05-03
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Genome expansion by a CRISPR trimmer-integrase.
Nature, 618, 2023
8FYB
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BU of 8fyb by Molmil
Cryo-EM structure of Cas1:Cas2-DEDDh:half-site integration complex
Descriptor: Cas1, Cas2-DEDDh, DNA (17-MER), ...
Authors:Skopintsev, P, Tuck, O.T, Soczek, K.M, Doudna, J.
Deposit date:2023-01-25
Release date:2023-05-03
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Genome expansion by a CRISPR trimmer-integrase.
Nature, 618, 2023
7S37
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BU of 7s37 by Molmil
Cas9:sgRNA (S. pyogenes) in the open-protein conformation
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Single-guide RNA
Authors:Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A.
Deposit date:2021-09-04
Release date:2022-04-20
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
7S36
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BU of 7s36 by Molmil
Cas9:sgRNA:DNA (S. pyogenes) with 0 RNA:DNA base pairs, closed-protein/bent-DNA conformation
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target DNA strand, Single-guide RNA, ...
Authors:Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A.
Deposit date:2021-09-04
Release date:2022-04-20
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
7S38
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BU of 7s38 by Molmil
Cas9:sgRNA:DNA (S. pyogenes) forming a 3-base-pair R-loop
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target DNA strand, Single-guide RNA, ...
Authors:Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A.
Deposit date:2021-09-04
Release date:2022-04-20
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
7S3H
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BU of 7s3h by Molmil
Cas9:sgRNA:DNA (S. pyogenes) with 0 RNA:DNA base pairs, open-protein/linear-DNA conformation
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target DNA strand, Single-guide RNA, ...
Authors:Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A.
Deposit date:2021-09-06
Release date:2022-04-20
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
8DC2
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BU of 8dc2 by Molmil
Cryo-EM structure of CasLambda (Cas12l) bound to crRNA and DNA
Descriptor: CasLambda, DNA NTS, DNA TS, ...
Authors:Al-Shayeb, B, Skopintsev, P, Soczek, K, Doudna, J.
Deposit date:2022-06-15
Release date:2022-12-14
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Diverse virus-encoded CRISPR-Cas systems include streamlined genome editors.
Cell, 185, 2022
7LYS
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BU of 7lys by Molmil
Cryo-EM structure of CasPhi-2 (Cas12j) bound to crRNA and DNA
Descriptor: CasPhi-2, NTS-DNA, TS-DNA, ...
Authors:Pausch, P, Soczek, K, Nogales, E, Doudna, J.
Deposit date:2021-03-08
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:DNA interference states of the hypercompact CRISPR-Cas Phi effector.
Nat.Struct.Mol.Biol., 28, 2021
7LYT
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BU of 7lyt by Molmil
Cryo-EM structure of CasPhi-2 (Cas12j) bound to crRNA and Phosphorothioate-DNA
Descriptor: CasPhi, MAGNESIUM ION, NTS-DNA*, ...
Authors:Pausch, P, Soczek, K, Nogales, E, Doudna, J.
Deposit date:2021-03-08
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:DNA interference states of the hypercompact CRISPR-Cas Phi effector.
Nat.Struct.Mol.Biol., 28, 2021
7M5O
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BU of 7m5o by Molmil
Cryo-EM structure of CasPhi-2 (Cas12j) bound to crRNA
Descriptor: CasPhi, ZINC ION, crRNA
Authors:Pausch, P, Soczek, K, Nogales, E, Doudna, J.
Deposit date:2021-03-24
Release date:2021-08-04
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:DNA interference states of the hypercompact CRISPR-Cas Phi effector.
Nat.Struct.Mol.Biol., 28, 2021
8ESC
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BU of 8esc by Molmil
Structure of the Yeast NuA4 Histone Acetyltransferase Complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ...
Authors:Patel, A.B, Zukin, S.A, Nogales, E.
Deposit date:2022-10-13
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure and flexibility of the yeast NuA4 histone acetyltransferase complex.
Elife, 11, 2022

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