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4NZH
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BU of 4nzh by Molmil
A. fumigatus flavin-dependent ornithine monooxygenase R279A mutant
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, L-ornithine, ...
Authors:Robinson, R, Franceschini, S, Sobrado, P.
Deposit date:2013-12-12
Release date:2015-03-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:A. fumigatus flavin-dependent ornithine monooxygenase R279A mutant
To be Published
2OZ0
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BU of 2oz0 by Molmil
Mechanistic and Structural Studies of H373Q Flavocytochrome b2: Effects of Mutating the Active Site Base
Descriptor: Cytochrome b2, FLAVIN MONONUCLEOTIDE, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Tsai, C.-L, Gokulan, K, Sobrado, P, Sacchettini, J.C, Fitzpatrick, P.F.
Deposit date:2007-02-23
Release date:2007-09-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanistic and structural studies of H373Q flavocytochrome b2: effects of mutating the active site base.
Biochemistry, 46, 2007
4D7E
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BU of 4d7e by Molmil
An unprecedented NADPH domain conformation in Lysine Monooxygenase NbtG from Nocardia farcinica
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, L-LYS MONOOXYGENASE
Authors:Binda, C, Robinson, R, Keul, N, Rodriguez, P, Robinson, H.H, Mattevi, A, Sobrado, P.
Deposit date:2014-11-24
Release date:2015-04-01
Last modified:2015-06-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:An Unprecedented Nadph Domain Conformation in Lysine Monooxygenase Nbtg Provides Insights Into Uncoupling of Oxygen Consumption from Substrate Hydroxylation.
J.Biol.Chem., 290, 2015
4B69
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BU of 4b69 by Molmil
A. fumigatus ornithine hydroxylase (SidA) bound to ornithine
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, L-ORNITHINE N5 MONOOXYGENASE, ...
Authors:Franceschini, S, Fedkenheuer, M, Vogelaar, N.J, Robinson, H.H, Sobrado, P, Mattevi, A.
Deposit date:2012-08-09
Release date:2012-10-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Insight Into the Mechanism of Oxygen Activation and Substrate Selectivity of Flavin-Dependent N-Hydroxylating Monooxygenases.
Biochemistry, 51, 2012
4B66
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BU of 4b66 by Molmil
A. fumigatus ornithine hydroxylase (SidA), reduced state bound to NADP and Arg
Descriptor: ARGININE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Franceschini, S, Fedkenheuer, M, Vogelaar, N.J, Robinson, H.H, Sobrado, P, Mattevi, A.
Deposit date:2012-08-09
Release date:2012-10-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Insight Into the Mechanism of Oxygen Activation and Substrate Selectivity of Flavin-Dependent N-Hydroxylating Monooxygenases.
Biochemistry, 51, 2012
4B63
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BU of 4b63 by Molmil
A. fumigatus ornithine hydroxylase (SidA) bound to NADP and ornithine
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, L-ORNITHINE N5 MONOOXYGENASE, ...
Authors:Franceschini, S, Fedkenheuer, M, Vogelaar, N.J, Robinson, H.H, Sobrado, P, Mattevi, A.
Deposit date:2012-08-09
Release date:2012-10-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insight Into the Mechanism of Oxygen Activation and Substrate Selectivity of Flavin-Dependent N-Hydroxylating Monooxygenases.
Biochemistry, 51, 2012
4B67
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BU of 4b67 by Molmil
A. fumigatus ornithine hydroxylase (SidA), re-oxidised state bound to NADP and ornithine
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, L-ORNITHINE N5 MONOOXYGENASE, ...
Authors:Franceschini, S, Fedkenheuer, M, Vogelaar, N.J, Robinson, H.H, Sobrado, P, Mattevi, A.
Deposit date:2012-08-09
Release date:2012-10-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Insight Into the Mechanism of Oxygen Activation and Substrate Selectivity of Flavin-Dependent N-Hydroxylating Monooxygenases.
Biochemistry, 51, 2012
4B64
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BU of 4b64 by Molmil
A. fumigatus ornithine hydroxylase (SidA) bound to NADP and Lysine
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, L-ORNITHINE N5 MONOOXYGENASE, ...
Authors:Franceschini, S, Fedkenheuer, M, Vogelaar, N.J, Robinson, H.H, Sobrado, P, Mattevi, A.
Deposit date:2012-08-09
Release date:2012-10-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural Insight Into the Mechanism of Oxygen Activation and Substrate Selectivity of Flavin-Dependent N-Hydroxylating Monooxygenases.
Biochemistry, 51, 2012
4B68
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BU of 4b68 by Molmil
A. fumigatus ornithine hydroxylase (SidA), re-oxidised state bound to NADP and Arg
Descriptor: ARGININE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Franceschini, S, Fedkenheuer, M, Vogelaar, N.J, Robinson, H.H, Sobrado, P, Mattevi, A.
Deposit date:2012-08-09
Release date:2012-10-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural Insight Into the Mechanism of Oxygen Activation and Substrate Selectivity of Flavin-Dependent N-Hydroxylating Monooxygenases.
Biochemistry, 51, 2012
4B65
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BU of 4b65 by Molmil
A. fumigatus ornithine hydroxylase (SidA), reduced state bound to NADP(H)
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, L-ORNITHINE N5 MONOOXYGENASE, ...
Authors:Franceschini, S, Fedkenheuer, M, Vogelaar, N.J, Robinson, H.H, Sobrado, P, Mattevi, A.
Deposit date:2012-08-09
Release date:2012-10-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structural Insight Into the Mechanism of Oxygen Activation and Substrate Selectivity of Flavin-Dependent N-Hydroxylating Monooxygenases.
Biochemistry, 51, 2012
4WX1
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BU of 4wx1 by Molmil
Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant F66A determined from a crystal soaked with UDP-Galactopyranose
Descriptor: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GLYCEROL, SULFATE ION, ...
Authors:Qureshi, I.A, Chaudhary, R.
Deposit date:2014-11-13
Release date:2014-12-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics.
Biochemistry, 53, 2014
7LRN
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BU of 7lrn by Molmil
Structure of the Siderophore Interacting Protein from Acinetbacter baumannii
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADPH-dependent ferric siderophore reductase
Authors:Tanner, J.J, Korasick, D.A.
Deposit date:2021-02-16
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural and Biochemical Characterization of the Flavin-Dependent Siderophore-Interacting Protein from Acinetobacter baumannii .
Acs Omega, 6, 2021
5HHF
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BU of 5hhf by Molmil
Crystal structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant H63A with covalent FAD-Galactopyranose and bound UDP
Descriptor: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, MESO-ERYTHRITOL, SULFATE ION, ...
Authors:Tanner, J.J.
Deposit date:2016-01-10
Release date:2016-02-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:In Crystallo Capture of a Covalent Intermediate in the UDP-Galactopyranose Mutase Reaction.
Biochemistry, 55, 2016
6C7S
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BU of 6c7s by Molmil
Structure of Rifampicin Monooxygenase with Product Bound
Descriptor: (1E,3S,4R,5S,6R,7R,8R,9S,10S,11E,13E)-15-amino-1-{[(2S)-5,7-dihydroxy-2,4-dimethyl-8-{(E)-[(4-methylpiperazin-1-yl)imino]methyl}-1,6,9-trioxo-1,2,6,9-tetrahydronaphtho[2,1-b]furan-2-yl]oxy}-7,9-dihydroxy-3-methoxy-4,6,8,10,14-pentamethyl-15-oxopentadeca-1,11,13-trien-5-yl acetate, 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Liu, L.-K, Tanner, J.J.
Deposit date:2018-01-23
Release date:2018-04-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Evidence for Rifampicin Monooxygenase Inactivating Rifampicin by Cleaving Its Ansa-Bridge.
Biochemistry, 57, 2018
4GDE
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BU of 4gde by Molmil
Crystal structure of NADPH-reduced Aspergillus fumigatus UDP-galactopyranose
Descriptor: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, UDP-galactopyranose mutase
Authors:Tanner, J.J, Dhatwalia, R.D, Singh, H.
Deposit date:2012-07-31
Release date:2012-10-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identification of the NAD(P)H Binding Site of Eukaryotic UDP-Galactopyranose Mutase.
J.Am.Chem.Soc., 134, 2012
7US3
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BU of 7us3 by Molmil
Structure of Putrescine N-hydroxylase Involved Complexed with NADP+
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putrescine N-hydroxylase, ...
Authors:Tanner, J.J, Bogner, A.N.
Deposit date:2022-04-22
Release date:2022-11-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Kinetic and Structural Characterization of a Flavin-Dependent Putrescine N -Hydroxylase from Acinetobacter baumannii.
Biochemistry, 61, 2022
5KOW
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BU of 5kow by Molmil
Structure of rifampicin monooxygenase
Descriptor: ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, Pentachlorophenol 4-monooxygenase
Authors:Tanner, J.J, Liu, L.-K.
Deposit date:2016-07-01
Release date:2016-09-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Structure of the Antibiotic Deactivating, N-hydroxylating Rifampicin Monooxygenase.
J.Biol.Chem., 291, 2016
5KOX
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BU of 5kox by Molmil
Structure of rifampicin monooxygenase complexed with rifampicin
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Pentachlorophenol 4-monooxygenase, RIFAMPICIN
Authors:Tanner, J.J, Liu, L.-K.
Deposit date:2016-07-01
Release date:2016-09-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Structure of the Antibiotic Deactivating, N-hydroxylating Rifampicin Monooxygenase.
J.Biol.Chem., 291, 2016
5VWT
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BU of 5vwt by Molmil
Crystal structure of oxidized Aspergillus fumigatus UDP-galactopyranose mutase complexed with NADPH
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ...
Authors:Tanner, J.J.
Deposit date:2017-05-22
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Identification of the NAD(P)H binding site of eukaryotic UDP-galactopyranose mutase.
J. Am. Chem. Soc., 134, 2012
5VWU
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BU of 5vwu by Molmil
Crystal structure of oxidized Aspergillus fumigatus UDP-galactopyranose mutase complexed with NADH
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ...
Authors:Tanner, J.J.
Deposit date:2017-05-22
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Identification of the NAD(P)H binding site of eukaryotic UDP-galactopyranose mutase.
J. Am. Chem. Soc., 134, 2012
7JVK
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BU of 7jvk by Molmil
Structure of the M101A variant of the SidA ornithine hydroxylase with the FAD in the "out" conformation
Descriptor: ACETATE ION, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-08-21
Release date:2020-12-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Determinants of Flavin Dynamics in a Class B Monooxygenase.
Biochemistry, 59, 2020
7JVL
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BU of 7jvl by Molmil
Structure of the M101A variant of the SidA ornithine hydroxylase complexed with NADP and the FAD in the "out" conformation
Descriptor: ACETATE ION, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-08-21
Release date:2020-12-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Determinants of Flavin Dynamics in a Class B Monooxygenase.
Biochemistry, 59, 2020
4YMK
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BU of 4ymk by Molmil
Crystal Structure of Stearoyl-Coenzyme A Desaturase 1
Descriptor: Acyl-CoA desaturase 1, STEAROYL-COENZYME A, ZINC ION, ...
Authors:Bai, Y, McCoy, J.G, Rajashankar, K.R, Zhou, M.
Deposit date:2015-03-06
Release date:2015-06-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.605 Å)
Cite:X-ray structure of a mammalian stearoyl-CoA desaturase.
Nature, 524, 2015
5CKU
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BU of 5cku by Molmil
Structure of Aspergillus fumigatus ornithine hydroxylase (SidA) mutant N323A bound to NADP and ornithine
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, L-ornithine, ...
Authors:Tanner, J.J, Qureshi, I.A.
Deposit date:2015-07-15
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Contribution to catalysis of ornithine binding residues in ornithine N5-monooxygenase.
Arch.Biochem.Biophys., 585, 2015
6X0K
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BU of 6x0k by Molmil
Structure of dithionite-reduced SidA ornithine hydroxylase with the FAD "in" and complexed with L-ornithine
Descriptor: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, L-ornithine, L-ornithine N(5)-monooxygenase
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-05-15
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.231 Å)
Cite:Trapping conformational states of a flavin-dependent N -monooxygenase in crystallo reveals protein and flavin dynamics.
J.Biol.Chem., 295, 2020

 

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