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3UMR
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CRYSTAL STRUCTURE OF THE G202D MUTANT OF HUMAN G-ALPHA-I1
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, ...
Authors:Johnston, C.A., Afshar, K., Snyder, J.T., Tall, G.G., Gonczy, P., Siderovski, D.P., Willard, F.S.
Deposit date:2011-11-14
Release date:2012-10-24
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural Determinants Underlying the Temperature-sensitive Nature of a G-alpha Mutant in Asymmetric Cell Division of Caenorhabditis elegans
To be Published
2ZKM
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CRYSTAL STRUCTURE OF PHOSPHOLIPASE C BETA 2
Descriptor:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2, CALCIUM ION
Authors:Hicks, S.N., Jezyk, M.R., Gershberg, S., Seifert, J.P., Harden, T.K., Sondek, J.
Deposit date:2008-03-26
Release date:2008-08-12
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:General and versatile autoinhibition of PLC isozymes
Mol.Cell, 31, 2008
2PBI
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THE MULTIFUNCTIONAL NATURE OF GBETA5/RGS9 REVEALED FROM ITS CRYSTAL STRUCTURE
Descriptor:Regulator of G-protein signaling 9, Guanine nucleotide-binding protein subunit beta 5, GLYCEROL
Authors:Cheever, M.L., Snyder, J.T., Gershburg, S., Siderovski, D.P., Harden, T.K., Sondek, J.
Deposit date:2007-03-28
Release date:2008-01-29
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the multifunctional Gbeta5-RGS9 complex.
Nat.Struct.Mol.Biol., 15, 2008
2FJU
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ACTIVATED RAC1 BOUND TO ITS EFFECTOR PHOSPHOLIPASE C BETA 2
Descriptor:Ras-related C3 botulinum toxin substrate 1, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2, MAGNESIUM ION, ...
Authors:Jezyk, M.R., Snyder, J.T., Harden, T.K., Sondek, J.
Deposit date:2006-01-03
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Rac1 bound to its effector phospholipase C-beta2.
Nat.Struct.Mol.Biol., 13, 2006
1LB1
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CRYSTAL STRUCTURE OF THE DBL AND PLECKSTRIN HOMOLOGY DOMAINS OF DBS IN COMPLEX WITH RHOA
Descriptor:Guanine nucleotide exchange factor DBS, Transforming protein RhoA
Authors:Snyder, J.T., Worthylake, D.K., Rossman, K.L., Betts, L., Pruitt, W.M., Siderovski, D.P., Der, C.J., Sondek, J.
Deposit date:2002-04-01
Release date:2002-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol., 9, 2002
1KZ7
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CRYSTAL STRUCTURE OF THE DH/PH FRAGMENT OF MURINE DBS IN COMPLEX WITH THE PLACENTAL ISOFORM OF HUMAN CDC42
Descriptor:GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS, CDC42 HOMOLOG
Authors:Rossman, K.L., Worthylake, D.K., Snyder, J.T., Siderovski, D.P., Campbell, S.L., Sondek, J.
Deposit date:2002-02-06
Release date:2002-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.
EMBO J., 21, 2002
1KZG
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DBSCDC42(Y889F)
Descriptor:GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS, CDC42 HOMOLOG
Authors:Rossman, K.L., Worthylake, D.K., Snyder, J.T., Siderovski, D.P., Campbell, S.L., Sondek, J.
Deposit date:2002-02-06
Release date:2002-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.
EMBO J., 21, 2002
1KI1
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GUANINE NUCLEOTIDE EXCHANGE REGION OF INTERSECTIN IN COMPLEX WITH CDC42
Descriptor:G25K GTP-binding protein, placental isoform, intersectin long form, ...
Authors:Snyder, J.T., Pruitt, W.M., Der, C.J., Sondek, J.
Deposit date:2001-12-02
Release date:2002-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol., 9, 2002