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6C5V
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BU of 6c5v by Molmil
An anti-gH/gL antibody that neutralizes dual-tropic infection defines a site of vulnerability on Epstein-Barr virus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab AMMO1 heavy chain, Antibody Fab AMMO1 light chain, ...
Authors:Snijder, J, Ortego, M.S, Weidle, C, Stuart, A.B, Gray, M.A, McElrath, M.J, Pancera, M, Veesler, D, McGuire, A.T, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-01-16
Release date:2018-05-02
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.
Immunity, 48, 2018
5N8Y
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BU of 5n8y by Molmil
KaiCBA circadian clock backbone model based on a Cryo-EM density
Descriptor: Circadian clock protein KaiA, Circadian clock protein KaiB, Circadian clock protein kinase KaiC
Authors:Schuller, J.M, Snijder, J, Loessl, P, Heck, A.J.R, Foerster, F.
Deposit date:2017-02-24
Release date:2017-03-29
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structures of the cyanobacterial circadian oscillator frozen in a fully assembled state.
Science, 355, 2017
5SZS
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BU of 5szs by Molmil
Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Walls, A.C, Tortorici, M.A, Frenz, B, Snijder, J, Li, W, Rey, F.A, DiMaio, F, Bosch, B.J, Veesler, D.
Deposit date:2016-08-15
Release date:2016-09-14
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy.
Nat.Struct.Mol.Biol., 23, 2016
6B3O
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BU of 6b3o by Molmil
Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion
Descriptor: Spike glycoprotein
Authors:Walls, A.C, Tortorici, M.A, Snijder, J, Xiong, X, Bosch, B.J, Rey, F.A, Veesler, D.
Deposit date:2017-09-22
Release date:2017-10-04
Last modified:2020-01-01
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6NB8
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BU of 6nb8 by Molmil
Crystal structure of anti- SARS-CoV human neutralizing S230 antibody Fab fragment
Descriptor: S230 antigen-binding (Fab) fragment, heavy chain, light chain
Authors:Walls, A.J, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, J, Quispe, J, Cameroni, E, Gopal, R, Dai, M, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB5
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BU of 6nb5 by Molmil
Crystal structure of anti- MERS-CoV human neutralizing LCA60 antibody Fab fragment
Descriptor: LCA60 antigen-binding (Fab) fragment, heavy chain, light chain
Authors:Walls, A.J, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, J, Quispe, J, Cameroni, E, Gopal, R, Dai, M, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6U1T
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BU of 6u1t by Molmil
Crystal structure of anti-Nipah virus (NiV) F 5B3 antibody Fab fragment
Descriptor: CHLORIDE ION, antigen-binding (Fab) fragment, heavy chain, ...
Authors:Dang, H.V, Chan, Y.P, Park, Y.J, Snijder, J, Da Silva, S.C, Vu, B, Yan, L, Feng, Y.R, Rockx, B, Geisbert, T, Mire, C, Mire, C.E, BBroder, C.C, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-08-16
Release date:2019-10-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.483 Å)
Cite:An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections.
Nat.Struct.Mol.Biol., 26, 2019
7BG1
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BU of 7bg1 by Molmil
Structure of anti-FLAG M2 Fab domain remodeled based on proteomic sequencing
Descriptor: CHLORIDE ION, SULFATE ION, anti-FLAG M2 heavy chain, ...
Authors:Pronker, M.F, Snijder, J.
Deposit date:2021-01-05
Release date:2021-07-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Mass Spectrometry-Based De Novo Sequencing of Monoclonal Antibodies Using Multiple Proteases and a Dual Fragmentation Scheme.
J.Proteome Res., 20, 2021
6TYS
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BU of 6tys by Molmil
A potent cross-neutralizing antibody targeting the fusion glycoprotein inhibits Nipah virus and Hendra virus infection
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5B3 antibody heavy chain, ...
Authors:Dang, H.V, Chan, Y.P, Park, Y.J, Snijder, J, Da Silva, S.C, Vu, B, Yan, L, Feng, Y.R, Rockx, B, Geisbert, T, Mire, C.E, Broder, C.B, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-08-09
Release date:2019-10-09
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections.
Nat.Struct.Mol.Biol., 26, 2019
6MYY
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BU of 6myy by Molmil
Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 3 Fabs bound, sharpened map
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ...
Authors:Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D.
Deposit date:2018-11-02
Release date:2018-11-14
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
6MZJ
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BU of 6mzj by Molmil
Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 2 Fabs bound, sharpened map
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ...
Authors:Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D.
Deposit date:2018-11-05
Release date:2018-11-14
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
6BLA
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BU of 6bla by Molmil
Structure of AMM01 Fab, an anti EBV gH/gL neutralizing antibody
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AMM01 Fab Heavy chain, ...
Authors:Pancera, M, Weidle, C, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-11-09
Release date:2018-04-25
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.
Immunity, 48, 2018
6BFU
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BU of 6bfu by Molmil
Glycan shield and fusion activation of a deltacoronavirus spike glycoprotein fine-tuned for enteric infections
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein, ...
Authors:Xiong, X, Tortorici, M.A, Snijder, S, Yoshioka, C, Walls, A.C, Li, W, Seattle Structural Genomics Center for Infectious Disease (SSGCID), McGuire, A.T, Rey, F.A, Bosch, B.J, Veesler, D.
Deposit date:2017-10-27
Release date:2017-11-22
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Glycan Shield and Fusion Activation of a Deltacoronavirus Spike Glycoprotein Fine-Tuned for Enteric Infections.
J. Virol., 92, 2018
6NB7
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BU of 6nb7 by Molmil
SARS-CoV complex with human neutralizing S230 antibody Fab fragment (state 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S230 heavy chain, ...
Authors:Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB4
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BU of 6nb4 by Molmil
MERS-CoV S complex with human neutralizing LCA60 antibody Fab fragment (state 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LCA60 heavy chain, ...
Authors:Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB6
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BU of 6nb6 by Molmil
SARS-CoV complex with human neutralizing S230 antibody Fab fragment (state 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S230 heavy chain, ...
Authors:Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB3
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BU of 6nb3 by Molmil
MERS-CoV complex with human neutralizing LCA60 antibody Fab fragment (state 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LCA60 heavy chain, ...
Authors:Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6Y3Y
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BU of 6y3y by Molmil
Human Coronavirus HKU1 Haemagglutinin-Esterase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-esterase, ...
Authors:Hurdiss, D.L, Drulyte, I, Pronker, M.F.
Deposit date:2020-02-19
Release date:2020-04-08
Last modified:2020-09-30
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans.
Nat Commun, 11, 2020
8A0Y
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BU of 8a0y by Molmil
Crystal structure of mouse contactin 2 immunoglobulin domains
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-2, ...
Authors:Chataigner, L.M.P, Janssen, B.J.C.
Deposit date:2022-05-30
Release date:2023-11-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Contactin 2 homophilic adhesion structure and conformational plasticity.
Structure, 32, 2024
8BON
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BU of 8bon by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the macrocyclic peptide S1B3inL1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrocyclic peptide S1B3inL1, ...
Authors:Hurdiss, D.L.
Deposit date:2022-11-15
Release date:2023-06-28
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein.
Proc.Natl.Acad.Sci.USA, 120, 2023
7PNQ
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BU of 7pnq by Molmil
Human coronavirus OC43 spike glycoprotein ectodomain in complex with the 43E6 antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 43E6 antibody heavy chain, 43E6 antibody light chain, ...
Authors:Hurdiss, D.L.
Deposit date:2021-09-07
Release date:2022-04-20
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes.
Nat Commun, 13, 2022
7PO5
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BU of 7po5 by Molmil
Human coronavirus OC43 spike glycoprotein ectodomain in complex with the 47C9 antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 47C9 antibody heavy chain, 47C9 antibody light chain, ...
Authors:Hurdiss, D.L.
Deposit date:2021-09-08
Release date:2022-04-20
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes.
Nat Commun, 13, 2022
7PNM
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BU of 7pnm by Molmil
Human coronavirus OC43 spike glycoprotein ectodomain in complex with the 46C12 antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 46C12 antibody heavy chain, ...
Authors:Hurdiss, D.L.
Deposit date:2021-09-07
Release date:2022-04-20
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes.
Nat Commun, 13, 2022
8OPN
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BU of 8opn by Molmil
Human Coronavirus HKU1 spike glycoprotein in complex with an alpha2,8-linked 9-O-acetylated disialoside (1-up state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 9-O-acetyl-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid-(2-8)-N-acetyl-alpha-neuraminic acid, ...
Authors:Pronker, M.F, Creutznacher, R, Hurdiss, D.L.
Deposit date:2023-04-07
Release date:2023-08-02
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Sialoglycan binding triggers spike opening in a human coronavirus.
Nature, 624, 2023
8OHN
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BU of 8ohn by Molmil
Human Coronavirus HKU1 spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Pronker, M.F, Hurdiss, D.L.
Deposit date:2023-03-21
Release date:2023-08-02
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Sialoglycan binding triggers spike opening in a human coronavirus.
Nature, 624, 2023

 

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