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1S78
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BU of 1s78 by Molmil
Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Pertuzumab Fab heavy chain, ...
Authors:Franklin, M.C, Carey, K.D, Vajdos, F.F, Leahy, D.J, de Vos, A.M, Sliwkowski, M.X.
Deposit date:2004-01-29
Release date:2004-04-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex.
Cancer Cell, 5, 2004
1M17
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BU of 1m17 by Molmil
Epidermal Growth Factor Receptor tyrosine kinase domain with 4-anilinoquinazoline inhibitor erlotinib
Descriptor: [6,7-BIS(2-METHOXY-ETHOXY)QUINAZOLINE-4-YL]-(3-ETHYNYLPHENYL)AMINE, epidermal growth factor receptor
Authors:Stamos, J, Sliwkowski, M.X, Eigenbrot, C.
Deposit date:2002-06-17
Release date:2002-09-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor.
J.Biol.Chem., 277, 2002
1M14
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BU of 1m14 by Molmil
Tyrosine Kinase Domain from Epidermal Growth Factor Receptor
Descriptor: Epidermal growth factor receptor
Authors:Stamos, J, Sliwkowski, M.X, Eigenbrot, C.
Deposit date:2002-06-17
Release date:2002-09-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor.
J.Biol.Chem., 277, 2002
1HAE
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BU of 1hae by Molmil
HEREGULIN-ALPHA EPIDERMAL GROWTH FACTOR-LIKE DOMAIN, NMR, 20 STRUCTURES
Descriptor: HEREGULIN-ALPHA
Authors:Jacobsen, N.E, Skelton, N.J, Fairbrother, W.J.
Deposit date:1995-11-30
Release date:1996-07-11
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:High-resolution solution structure of the EGF-like domain of heregulin-alpha.
Biochemistry, 35, 1996
1HAF
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BU of 1haf by Molmil
HEREGULIN-ALPHA EPIDERMAL GROWTH FACTOR-LIKE DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: HEREGULIN-ALPHA
Authors:Jacobsen, N.E, Skelton, N.J, Fairbrother, W.J.
Deposit date:1995-11-30
Release date:1996-07-11
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:High-resolution solution structure of the EGF-like domain of heregulin-alpha.
Biochemistry, 35, 1996
3P11
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BU of 3p11 by Molmil
anti-EGFR/HER3 Fab DL11 in complex with domains I-III of the HER3 extracellular region
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab DL11 heavy chain, ...
Authors:Eigenbrot, C, Shia, S.
Deposit date:2010-09-29
Release date:2011-10-26
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.
Cancer Cell, 20, 2011
3P0Y
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BU of 3p0y by Molmil
anti-EGFR/HER3 Fab DL11 in complex with domain III of EGFR extracellular region
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
Authors:Eigenbrot, C, Shia, S.
Deposit date:2010-09-29
Release date:2011-10-26
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.
Cancer Cell, 20, 2011
3P0V
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BU of 3p0v by Molmil
anti-EGFR/HER3 Fab DL11 alone
Descriptor: CALCIUM ION, Fab DL11 heavy chain, Fab DL11 light chain
Authors:Eigenbrot, C, Shia, S.
Deposit date:2010-09-29
Release date:2011-10-19
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.
Cancer Cell, 20, 2011

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