4NFF
| Human kallikrein-related peptidase 2 in complex with PPACK | Descriptor: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Kallikrein-2 | Authors: | Skala, W, Brandstetter, H, Magdolen, V, Goettig, P. | Deposit date: | 2013-10-31 | Release date: | 2014-10-29 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity J.Biol.Chem., 289, 2014
|
|
4NFE
| Human kallikrein-related peptidase 2 in complex with benzamidine | Descriptor: | BENZAMIDINE, Kallikrein-2, SULFATE ION | Authors: | Skala, W, Brandstetter, H, Magdolen, V, Goettig, P. | Deposit date: | 2013-10-31 | Release date: | 2014-10-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity J.Biol.Chem., 289, 2014
|
|
5MS3
| Kallikrein-related peptidase 8 calcium complex | Descriptor: | CALCIUM ION, Kallikrein-8 | Authors: | Debela, M, Magdolen, V, Skala, W, Bode, W, Brandstetter, H, Goettig, P. | Deposit date: | 2016-12-30 | Release date: | 2018-01-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Specificity profiles and antagonistic Ca2+ and Zn2+ regulation of human KLK8/neuropsin activity by modules identified in crystal structures To Be Published
|
|
5MS4
| Kallikrein-related peptidase 8 leupeptin inhibitor complex | Descriptor: | CALCIUM ION, Kallikrein-8, LEUPEPTIN, ... | Authors: | Debela, M, Magdolen, V, Skala, W, Bode, W, Brandstetter, H, Goettig, P. | Deposit date: | 2016-12-30 | Release date: | 2018-01-17 | Last modified: | 2019-10-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin. Sci Rep, 8, 2018
|
|