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7PCK
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BU of 7pck by Molmil
CRYSTAL STRUCTURE OF WILD TYPE HUMAN PROCATHEPSIN K
Descriptor: PROTEIN (PROCATHEPSIN K)
Authors:Sivaraman, J, Lalumiere, M, Menard, R, Cygler, M.
Deposit date:1998-10-21
Release date:1999-10-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of wild-type human procathepsin K.
Protein Sci., 8, 1999
1ZPS
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BU of 1zps by Molmil
Crystal structure of Methanobacterium thermoautotrophicum phosphoribosyl-AMP cyclohydrolase HisI
Descriptor: ACETIC ACID, CADMIUM ION, Phosphoribosyl-AMP cyclohydrolase
Authors:Sivaraman, J, Myers, R.S, Boju, L, Sulea, T, Cygler, M, Davisson, V.J, Schrag, J.D, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2005-05-17
Release date:2005-08-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Methanobacterium thermoautotrophicum Phosphoribosyl-AMP Cyclohydrolase HisI.
Biochemistry, 44, 2005
1PS6
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BU of 1ps6 by Molmil
Crystal structure of E.coli PdxA
Descriptor: 4-HYDROXY-L-THREONINE-5-MONOPHOSPHATE, 4-hydroxythreonine-4-phosphate dehydrogenase, ZINC ION
Authors:Sivaraman, J, Li, Y, Banks, J, Cane, D.E, Matte, A, Cygler, M.
Deposit date:2003-06-20
Release date:2003-11-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway
J.Biol.Chem., 278, 2003
1PS7
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BU of 1ps7 by Molmil
Crystal structure of E.coli PdxA
Descriptor: 4-hydroxythreonine-4-phosphate dehydrogenase, ZINC ION
Authors:Sivaraman, J, Li, Y, Banks, J, Cane, D.E, Matte, A, Cygler, M.
Deposit date:2003-06-20
Release date:2003-11-04
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway
J.Biol.Chem., 278, 2003
1PTM
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BU of 1ptm by Molmil
Crystal structure of E.coli PdxA
Descriptor: 4-hydroxythreonine-4-phosphate dehydrogenase, PHOSPHATE ION, ZINC ION
Authors:Sivaraman, J, Li, Y, Banks, J, Cane, D.E, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2003-06-23
Release date:2003-11-04
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway
J.Biol.Chem., 278, 2003
1PRZ
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BU of 1prz by Molmil
Crystal structure of pseudouridine synthase RluD catalytic module
Descriptor: Ribosomal large subunit pseudouridine synthase D
Authors:Sivaraman, J, Iannuzzi, P, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2003-06-20
Release date:2003-11-04
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the RluD pseudouridine Synthase catalytic module, an enzyme that modifies 23S rRNA and is essential for normal cell growth of Escherichia coli
J.Mol.Biol., 335, 2003
1DEU
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BU of 1deu by Molmil
CRYSTAL STRUCTURE OF HUMAN PROCATHEPSIN X: A CYSTEINE PROTEASE WITH THE PROREGION COVALENTLY LINKED TO THE ACTIVE SITE CYSTEINE
Descriptor: PROCATHEPSIN X
Authors:Sivaraman, J, Nagler, D.K, Zhang, R, Menard, R, Cygler, M.
Deposit date:1999-11-15
Release date:2000-02-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine.
J.Mol.Biol., 295, 2000
1FG7
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BU of 1fg7 by Molmil
CRYSTAL STRUCTURE OF L-HISTIDINOL PHOSPHATE AMINOTRANSFERASE WITH PYRIDOXAL-5'-PHOSPHATE
Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, HISTIDINOL PHOSPHATE AMINOTRANSFERASE
Authors:Sivaraman, J, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2000-07-28
Release date:2001-08-22
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of histidinol phosphate aminotransferase (HisC) from Escherichia coli, and its covalent complex with pyridoxal-5'-phosphate and l-histidinol phosphate.
J.Mol.Biol., 311, 2001
1FG3
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BU of 1fg3 by Molmil
CRYSTAL STRUCTURE OF L-HISTIDINOL PHOSPHATE AMINOTRANSFERASE COMPLEXED WITH L-HISTIDINOL
Descriptor: HISTIDINOL PHOSPHATE AMINOTRANSFERASE, PHOSPHORIC ACID MONO-[2-AMINO-3-(3H-IMIDAZOL-4-YL)-PROPYL]ESTER, PYRIDOXAL-5'-PHOSPHATE
Authors:Sivaraman, J, Cygler, M.
Deposit date:2000-07-27
Release date:2001-08-22
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of histidinol phosphate aminotransferase (HisC) from Escherichia coli, and its covalent complex with pyridoxal-5'-phosphate and l-histidinol phosphate.
J.Mol.Biol., 311, 2001
1IJI
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BU of 1iji by Molmil
Crystal Structure of L-Histidinol Phosphate Aminotransferase with PLP
Descriptor: Histidinol Phosphate Aminotransferase, PYRIDOXAL-5'-PHOSPHATE
Authors:Sivaraman, J, Li, Y, Larocque, R, Schrag, J.D, Cygler, M, Matte, A.
Deposit date:2001-04-26
Release date:2001-08-29
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of histidinol phosphate aminotransferase (HisC) from Escherichia coli, and its covalent complex with pyridoxal-5'-phosphate and l-histidinol phosphate.
J.Mol.Biol., 311, 2001
1KSL
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BU of 1ksl by Molmil
STRUCTURE OF RSUA
Descriptor: RIBOSOMAL SMALL SUBUNIT PSEUDOURIDINE SYNTHASE A, URACIL
Authors:Sivaraman, J, Sauve, V, Larocque, R, Stura, E.A, Schrag, J.D, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2002-01-13
Release date:2002-04-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP.
Nat.Struct.Biol., 9, 2002
1KSV
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BU of 1ksv by Molmil
STRUCTURE OF RSUA
Descriptor: RIBOSOMAL SMALL SUBUNIT PSEUDOURIDINE SYNTHASE A, URIDINE-5'-MONOPHOSPHATE
Authors:Sivaraman, J, Sauve, V, Larocque, R, Stura, E.A, Schrag, J.D, Cygler, M, Matte, A.
Deposit date:2002-01-14
Release date:2002-04-24
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP.
Nat.Struct.Biol., 9, 2002
1KSK
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BU of 1ksk by Molmil
STRUCTURE OF RSUA
Descriptor: RIBOSOMAL SMALL SUBUNIT PSEUDOURIDINE SYNTHASE A, URACIL
Authors:Sivaraman, J, Sauve, V, Larocque, R, Stura, E.A, Schrag, J.D, Cygler, M, Matte, A.
Deposit date:2002-01-13
Release date:2002-04-24
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP.
Nat.Struct.Biol., 9, 2002
1MC3
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BU of 1mc3 by Molmil
CRYSTAL STRUCTURE OF RFFH
Descriptor: GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE
Authors:Sivaraman, J, Sauve, V, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2002-08-05
Release date:2002-11-20
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Escherichia coli Glucose-1-Phosphate Thymidylyltransferase (RffH) Complexed with dTTP and Mg2+
J.BIOL.CHEM., 277, 2002
5JYO
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BU of 5jyo by Molmil
Allosteric inhibition of Kidney Isoform of Glutaminase
Descriptor: 2-(pyridin-2-yl)-N-(5-{4-[6-({[3-(trifluoromethoxy)phenyl]acetyl}amino)pyridazin-3-yl]butyl}-1,3,4-thiadiazol-2-yl)acetamide, Glutaminase kidney isoform, mitochondrial
Authors:Sivaraman, J, Jayaraman, S.
Deposit date:2016-05-15
Release date:2016-08-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.098 Å)
Cite:Structural basis for exploring the allosteric inhibition of human kidney type glutaminase.
Oncotarget, 7, 2016
6JX6
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BU of 6jx6 by Molmil
Tetrameric form of Smac
Descriptor: Diablo homolog, mitochondrial
Authors:Sivaraman, J, Singh, S, Ng, J, Nayak, D.
Deposit date:2019-04-22
Release date:2019-12-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.805 Å)
Cite:Structural insights into a HECT-type E3 ligase AREL1 and its ubiquitination activitiesin vitro.
J.Biol.Chem., 294, 2019
6JX5
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BU of 6jx5 by Molmil
Hect domain of AREL1
Descriptor: Apoptosis-resistant E3 ubiquitin protein ligase 1
Authors:Sivaraman, J, Singh, S, Ng, J, Nayak, D.
Deposit date:2019-04-22
Release date:2019-12-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Structural insights into a HECT-type E3 ligase AREL1 and its ubiquitination activitiesin vitro.
J.Biol.Chem., 294, 2019
5DIN
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BU of 5din by Molmil
Structural Basis for the Indispensable Role of a Unique Zinc Finger Motif in LNX2 Ubiquitination
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ligand of Numb protein X 2, ZINC ION
Authors:Sivaraman, J, Nayak, D.
Deposit date:2015-09-01
Release date:2015-10-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.864 Å)
Cite:Structural basis for the indispensable role of a unique zinc finger motif in LNX2 ubiquitination.
Oncotarget, 6, 2015
5IAO
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BU of 5iao by Molmil
Structure and mapping of spontaneous mutational sites of PyrR from Mycobacterium tuberculosis
Descriptor: 5-FLUOROURACIL, Bifunctional protein PyrR
Authors:Sivaraman, J, Ghode, P, Ramachandran, S.
Deposit date:2016-02-21
Release date:2016-03-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:Structure and mapping of spontaneous mutational sites of PyrR from Mycobacterium tuberculosis
Biochem.Biophys.Res.Commun., 471, 2016
3LCV
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BU of 3lcv by Molmil
Crystal Structure of Antibiotic related Methyltransferase
Descriptor: S-ADENOSYLMETHIONINE, Sisomicin-gentamicin resistance methylase Sgm
Authors:Sivaraman, J, Husain, N.
Deposit date:2010-01-11
Release date:2010-06-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases.
Nucleic Acids Res., 2010
6K2C
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BU of 6k2c by Molmil
Extended Hect domain of UBE3C E3 Ligase
Descriptor: Ubiquitin-protein ligase E3C
Authors:Sivaraman, J, Singh, S.
Deposit date:2019-05-14
Release date:2020-03-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Crystal structure of HECT domain of UBE3C E3 ligase and its ubiquitination activity.
Biochem.J., 477, 2020
3VK6
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BU of 3vk6 by Molmil
Crystal structure of a phosphotyrosine binding domain
Descriptor: E3 ubiquitin-protein ligase Hakai, ZINC ION
Authors:Sivaraman, J, Mukherjee, M.
Deposit date:2011-11-09
Release date:2012-01-25
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherin
Embo J., 31, 2012
3P2K
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Structure of an antibiotic related Methyltransferase
Descriptor: 16S rRNA methylase, S-ADENOSYLMETHIONINE
Authors:Sivaraman, J, Husain, N.
Deposit date:2010-10-02
Release date:2010-11-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit.
Nucleic Acids Res., 39, 2011
3P2E
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BU of 3p2e by Molmil
Structure of an antibiotic related Methyltransferase
Descriptor: 16S rRNA methylase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Sivaraman, J, Husain, N.
Deposit date:2010-10-02
Release date:2010-11-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit.
Nucleic Acids Res., 2010
3P2I
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BU of 3p2i by Molmil
Structure of an antibiotic related Methyltransferase
Descriptor: 16S rRNA methylase
Authors:Sivaraman, J, Husain, N.
Deposit date:2010-10-02
Release date:2010-11-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit.
Nucleic Acids Res., 39, 2011

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