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2P4N
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BU of 2p4n by Molmil
Human Monomeric Kinesin (1BG2) and Bovine Tubulin (1JFF) Docked into the 9-Angstrom Cryo-EM Map of Nucleotide-Free Kinesin Complexed to the Microtubule
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Sindelar, C.V, Downing, K.H.
Deposit date:2007-03-12
Release date:2008-07-08
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (9 Å)
Cite:The beginning of kinesin's force-generating cycle visualized at 9-A resolution.
J.Cell Biol., 177, 2007
1MKJ
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BU of 1mkj by Molmil
Human Kinesin Motor Domain With Docked Neck Linker
Descriptor: ADENOSINE-5'-DIPHOSPHATE, KINESIN HEAVY CHAIN, MAGNESIUM ION, ...
Authors:Sindelar, C.V, Budny, M.J, Rice, S, Naber, N, Fletterick, R, Cooke, R.
Deposit date:2002-08-29
Release date:2002-10-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Two conformations in the human kinesin power stroke defined by X-ray crystallography and EPR spectroscopy.
Nat.Struct.Biol., 9, 2002
5KG8
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BU of 5kg8 by Molmil
Rigor myosin X co-complexed with an actin filament
Descriptor: Actin, alpha skeletal muscle, Unconventional myosin-X
Authors:Sindelar, C.V, Houdusse, A, Sweeney, L.
Deposit date:2016-06-12
Release date:2016-09-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:The myosin X motor is optimized for movement on actin bundles.
Nat Commun, 7, 2016
3DCO
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BU of 3dco by Molmil
Drosophila NOD (3DC4) and Bovine Tubulin (1JFF) Docked into the 11-Angstrom Cryo-EM Map of Nucleotide-Free NOD Complexed to the Microtubule
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Bovine Alpha Tubulin, Bovine Beta Tubulin, ...
Authors:Sindelar, C.V, Cochran, J.C, Kull, F.J.
Deposit date:2008-06-04
Release date:2009-02-10
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (11 Å)
Cite:ATPase cycle of the nonmotile kinesin NOD allows microtubule end tracking and drives chromosome movement.
Cell(Cambridge,Mass.), 136, 2009
6PWB
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BU of 6pwb by Molmil
Rigid body fitting of flagellin FlaB, and flagellar coiling proteins, FcpA and FcpB, into a 10 Angstrom structure of the asymmetric flagellar filament purified from Leptospira biflexa Patoc WT cells resolved via subtomogram averaging
Descriptor: Flagellar coiling protein A (FcpA), Flagellar coiling protein B (FcpB), Flagellin B1 (FlaB1)
Authors:Gibson, K.H, Sindelar, C.V, Trajtenberg, F, Buschiazzo, A, San Martin, F, Mechaly, A.
Deposit date:2019-07-22
Release date:2020-03-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (9.83 Å)
Cite:An asymmetric sheath controls flagellar supercoiling and motility in the leptospira spirochete.
Elife, 9, 2020
8UZ0
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BU of 8uz0 by Molmil
Straight actin filament from Arp2/3 branch junction sample (ADP)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Chavali, S.S, Chou, S.Z, Sindelar, C.V.
Deposit date:2023-11-14
Release date:2024-01-31
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex.
Nat Commun, 15, 2024
8UXW
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BU of 8uxw by Molmil
Arp2/3 branch junction complex, ADP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Chavali, S.S, Chou, S.Z, Sindelar, C.V.
Deposit date:2023-11-11
Release date:2024-01-31
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex.
Nat Commun, 15, 2024
8UXX
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BU of 8uxx by Molmil
Arp2/3 branch junction complex, BeFx state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Chavali, S.S, Chou, S.Z, Sindelar, C.V.
Deposit date:2023-11-11
Release date:2024-01-31
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex.
Nat Commun, 15, 2024
8UZ1
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BU of 8uz1 by Molmil
Straight actin filament from Arp2/3 branch junction sample (ADP-BeFx)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Chavali, S.S, Chou, S.Z, Sindelar, C.V.
Deposit date:2023-11-14
Release date:2024-01-31
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex.
Nat Commun, 15, 2024
2XRP
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BU of 2xrp by Molmil
Human Doublecortin N-DC Repeat (1MJD) and Mammalian Tubulin (1JFF and 3HKE) Docked into the 8-Angstrom Cryo-EM Map of Doublecortin- Stabilised Microtubules
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, NEURONAL MIGRATION PROTEIN DOUBLECORTIN, ...
Authors:Fourniol, F.J, Sindelar, C.V, Amigues, B, Clare, D.K, Thomas, G, Perderiset, M, Francis, F, Houdusse, A, Moores, C.A.
Deposit date:2010-09-18
Release date:2010-11-24
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:Template-Free 13-Protofilament Microtubule-Map Assembly Visualized at 8 A Resolution.
J.Cell Biol., 191, 2010
6D8C
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BU of 6d8c by Molmil
Cryo-EM structure of FLNaABD E254K bound to phalloidin-stabilized F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Iwamoto, D.V, Huehn, A.R, Simon, B, Huet-Calderwood, C, Baldassarre, M, Sindelar, C.V, Calderwood, D.A.
Deposit date:2018-04-26
Release date:2018-09-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structural basis of the filamin A actin-binding domain interaction with F-actin.
Nat. Struct. Mol. Biol., 25, 2018
3J8X
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BU of 3j8x by Molmil
High-resolution structure of no-nucleotide kinesin on microtubules
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ...
Authors:Shang, Z, Zhou, K, Xu, C, Csencsits, R, Cochran, J.C, Sindelar, C.V.
Deposit date:2014-11-20
Release date:2014-12-10
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (5 Å)
Cite:High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation.
Elife, 3, 2014
3J8Y
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BU of 3j8y by Molmil
High-resolution structure of ATP analog-bound kinesin on microtubules
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Shang, Z, Zhou, K, Xu, C, Csencsits, R, Cochran, J.C, Sindelar, C.V.
Deposit date:2014-11-20
Release date:2014-12-10
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (5 Å)
Cite:High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation.
Elife, 3, 2014
6C1H
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BU of 6c1h by Molmil
High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V.
Deposit date:2018-01-04
Release date:2018-01-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6C1D
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BU of 6c1d by Molmil
High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V.
Deposit date:2018-01-04
Release date:2018-01-31
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6C1G
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BU of 6c1g by Molmil
High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V.
Deposit date:2018-01-04
Release date:2018-01-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6WVR
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BU of 6wvr by Molmil
Tubulin dimers from a 13-protofilament, Taxol stabilized microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Debs, G.E, Cha, M, Huehn, A.R, Sindelar, C.V.
Deposit date:2020-05-06
Release date:2020-05-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Dynamic and asymmetric fluctuations in the microtubule wall captured by high-resolution cryoelectron microscopy.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WVM
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BU of 6wvm by Molmil
High curvature lateral interaction within a 13-protofilament, Taxol stabilized microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Debs, G.E, Cha, M, Huehn, A.R, Sindelar, C.V.
Deposit date:2020-05-06
Release date:2020-05-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Dynamic and asymmetric fluctuations in the microtubule wall captured by high-resolution cryoelectron microscopy.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WVL
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BU of 6wvl by Molmil
Low curvature lateral interaction within a 13-protofilament, Taxol stabilized microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Debs, G.E, Cha, M, Huehn, A.R, Sindelar, C.V.
Deposit date:2020-05-06
Release date:2020-05-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Dynamic and asymmetric fluctuations in the microtubule wall captured by high-resolution cryoelectron microscopy.
Proc.Natl.Acad.Sci.USA, 117, 2020
4AQV
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BU of 4aqv by Molmil
Model of human kinesin-5 motor domain (3HQD) and mammalian tubulin heterodimer (1JFF) docked into the 9.7-angstrom cryo-EM map of microtubule-bound kinesin-5 motor domain in the AMPPPNP state.
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-LIKE PROTEIN KIF11, ...
Authors:Goulet, A, Behnke-Parks, W.M, Sindelar, C.V, Rosenfeld, S.S, Moores, C.A.
Deposit date:2012-04-19
Release date:2012-11-21
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (9.7 Å)
Cite:The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5.
J.Biol.Chem., 287, 2012
4AQW
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BU of 4aqw by Molmil
Model of human kinesin-5 motor domain (1II6, 3HQD) and mammalian tubulin heterodimer (1JFF) docked into the 9.5-angstrom cryo-EM map of microtubule-bound kinesin-5 motor domain in the rigor state.
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-LIKE PROTEIN KIF11, ...
Authors:Goulet, A, Behnke-Parks, W.M, Sindelar, C.V, Rosenfeld, S.S, Moores, C.A.
Deposit date:2012-04-19
Release date:2012-11-21
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5.
J.Biol.Chem., 287, 2012
7T7X
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BU of 7t7x by Molmil
Munc13-1 C1-C2B-MUN-C2C Upright conformation spanning two lipid bilayers
Descriptor: Protein unc-13 homolog A
Authors:Grushin, K, Sindelar, C.V.
Deposit date:2021-12-15
Release date:2022-02-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Munc13 structural transitions and oligomers that may choreograph successive stages in vesicle priming for neurotransmitter release.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T7C
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BU of 7t7c by Molmil
The hexagonal organization of Munc13-1 C1-C2B-MUN-C2C domains between lipid bilayers
Descriptor: Protein unc-13 homolog A Chimera
Authors:Grushin, K, Sindelar, C.V.
Deposit date:2021-12-15
Release date:2022-02-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Munc13 structural transitions and oligomers that may choreograph successive stages in vesicle priming for neurotransmitter release.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T7V
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BU of 7t7v by Molmil
Munc13-1 C1-C2B-MUN-C2C Lateral conformation on lipid bilayer surface
Descriptor: Protein unc-13 homolog A
Authors:Grushin, K, Sindelar, C.V.
Deposit date:2021-12-15
Release date:2022-02-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Munc13 structural transitions and oligomers that may choreograph successive stages in vesicle priming for neurotransmitter release.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T81
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BU of 7t81 by Molmil
Model of Munc13-1 C1-C2B-MUN-C2C 2D crystal between lipid bilayers.
Descriptor: Protein unc-13 homolog A
Authors:Grushin, K, Sindelar, C.V.
Deposit date:2021-12-15
Release date:2022-02-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Munc13 structural transitions and oligomers that may choreograph successive stages in vesicle priming for neurotransmitter release.
Proc.Natl.Acad.Sci.USA, 119, 2022

 

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