Search by PDB author

PRO REGION C-TERMINUS: PROTEASE ACTIVE SITE INTERACTIONS ARE CRITICAL IN CATALYZING THE FOLDING OF ALPHA-LYTIC PROTEASE
Descriptor:	PROTEIN (ALPHA-LYTIC PROTEASE), SULFATE ION
Authors:	Peters, R.J, Shiau, A.K, Sohl, J.L, Anderson, D.E, Tang, G, Silen, J.L, Agard, D.A.
Deposit date:	1998-08-05
Release date:	1998-08-12
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Pro region C-terminus:protease active site interactions are critical in catalyzing the folding of alpha-lytic protease. Biochemistry, 37, 1998

9LPR

STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Bone, R, Agard, D.A.
Deposit date:	1991-08-05
Release date:	1993-01-15
Last modified:	2012-12-12
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991

5LPR

STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Fujishige, A, Bone, R, Agard, D.A.
Deposit date:	1991-08-05
Release date:	1993-01-15
Last modified:	2012-12-12
Method:	X-RAY DIFFRACTION (2.13 Å)
Cite:	Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991

7LPR

STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Fujishige, A, Bone, R, Agard, D.A.
Deposit date:	1991-08-05
Release date:	1993-01-15
Last modified:	2012-12-12
Method:	X-RAY DIFFRACTION (2.05 Å)
Cite:	Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991

8LPR

STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Fujishige, A, Bone, R, Agard, D.A.
Deposit date:	1991-08-05
Release date:	1993-01-15
Last modified:	2012-12-12
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991

6LPR

STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-NORLEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Bone, R, Agard, D.A.
Deposit date:	1991-08-05
Release date:	1993-01-15
Last modified:	2012-12-12
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991

3LPR

STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-NORLEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Bone, R, Agard, D.A.
Deposit date:	1991-08-05
Release date:	1993-01-15
Last modified:	2012-12-12
Method:	X-RAY DIFFRACTION (2.15 Å)
Cite:	Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991

2LPR

STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-VALINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Bone, R, Agard, D.A.
Deposit date:	1991-08-05
Release date:	1993-01-15
Last modified:	2012-12-12
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991

1P10

STRUCTURAL PLASTICITY AS A DETERMINANT OF ENZYME SPECIFICITY. CREATING BROADLY SPECIFIC PROTEASES
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-VALINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Bone, R, Agard, D.A.
Deposit date:	1989-04-24
Release date:	1990-04-15
Last modified:	2012-12-12
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	Structural plasticity broadens the specificity of an engineered protease. Nature, 339, 1989

1P09

STRUCTURAL PLASTICITY AS A DETERMINANT OF ENZYME SPECIFICITY. CREATING BROADLY SPECIFIC PROTEASES
Descriptor:	ALPHA-LYTIC PROTEASE, SULFATE ION
Authors:	Bone, R, Agard, D.A.
Deposit date:	1989-04-24
Release date:	1990-04-15
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Structural plasticity broadens the specificity of an engineered protease. Nature, 339, 1989

2ULL

MULTIPLE CONFORMATION STRUCTURE OF ALPHA-LYTIC PROTEASE AT 120 K
Descriptor:	ALPHA-LYTIC PROTEASE, SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE
Authors:	Rader, S.D, Agard, D.A.
Deposit date:	1996-11-26
Release date:	1997-07-07
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Conformational substates in enzyme mechanism: the 120 K structure of alpha-lytic protease at 1.5 A resolution. Protein Sci., 6, 1997

1P04

STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ISOLEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Bone, R, Agard, D.A.
Deposit date:	1989-04-24
Release date:	1990-04-15
Last modified:	2012-12-12
Method:	X-RAY DIFFRACTION (2.55 Å)
Cite:	Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. Biochemistry, 28, 1989

1P01

Serine protease mechanism. structure of an inhibitory complex oF ALPHA-LYTIC Protease and a tightly bound peptide boronic acid
Descriptor:	ALPHA-LYTIC PROTEASE, N-(tert-butoxycarbonyl)-L-alanyl-N-[(1R)-1-(dihydroxyboranyl)-2-methylpropyl]-L-prolinamide, SULFATE ION
Authors:	Bone, R, Agard, D.A.
Deposit date:	1989-04-24
Release date:	1990-04-15
Last modified:	2012-12-12
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Serine protease mechanism: structure of an inhibitory complex of alpha-lytic protease and a tightly bound peptide boronic acid. Biochemistry, 26, 1987

1P03

STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-VALINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Bone, R, Agard, D.A.
Deposit date:	1989-04-24
Release date:	1990-04-15
Last modified:	2012-12-12
Method:	X-RAY DIFFRACTION (2.15 Å)
Cite:	Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. Biochemistry, 28, 1989

1P05

STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-NORLEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Bone, R, Agard, D.A.
Deposit date:	1989-04-24
Release date:	1990-04-15
Last modified:	2012-12-12
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. Biochemistry, 28, 1989

1P06

STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Bone, R, Agard, D.A.
Deposit date:	1989-04-24
Release date:	1990-04-15
Last modified:	2012-12-12
Method:	X-RAY DIFFRACTION (2.34 Å)
Cite:	Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. Biochemistry, 28, 1989

1P02

STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Bone, R, Agard, D.A.
Deposit date:	1989-04-24
Release date:	1990-04-15
Last modified:	2012-12-12
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. Biochemistry, 28, 1989

1GBF

ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Mace, J.E, Agard, D.A.
Deposit date:	1995-09-06
Release date:	1996-01-29
Last modified:	2012-12-12
Method:	X-RAY DIFFRACTION (2.15 Å)
Cite:	Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. J.Mol.Biol., 254, 1995

1GBD

ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Mace, J.E, Agard, D.A.
Deposit date:	1995-09-06
Release date:	1996-01-29
Last modified:	2021-11-03
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. J.Mol.Biol., 254, 1995

1GBK

ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Mace, J.E, Agard, D.A.
Deposit date:	1995-09-06
Release date:	1996-01-29
Last modified:	2012-12-12
Method:	X-RAY DIFFRACTION (2.13 Å)
Cite:	Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. J.Mol.Biol., 254, 1995

1GBB

Alpha-lytic protease with met 190 replaced by ALA AND GLY 216 replaced by ALA complex with METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Mace, J.E, Agard, D.A.
Deposit date:	1995-09-06
Release date:	1996-01-29
Last modified:	2012-12-12
Method:	X-RAY DIFFRACTION (2.15 Å)
Cite:	Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. J.Mol.Biol., 254, 1995

1GBA

ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA
Descriptor:	ALPHA-LYTIC PROTEASE, SULFATE ION
Authors:	Mace, J.E, Agard, D.A.
Deposit date:	1995-09-06
Release date:	1996-01-29
Last modified:	2021-11-03
Method:	X-RAY DIFFRACTION (2.15 Å)
Cite:	Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. J.Mol.Biol., 254, 1995

1GBE

ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU
Descriptor:	ALPHA-LYTIC PROTEASE, SULFATE ION
Authors:	Mace, J.E, Agard, D.A.
Deposit date:	1995-09-06
Release date:	1996-01-29
Last modified:	2021-11-03
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. J.Mol.Biol., 254, 1995

1GBH

ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID
Descriptor:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:	Mace, J.E, Agard, D.A.
Deposit date:	1995-09-06
Release date:	1996-01-29
Last modified:	2021-11-03
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. J.Mol.Biol., 254, 1995

1GBJ

ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA
Descriptor:	ALPHA-LYTIC PROTEASE, SULFATE ION
Authors:	Mace, J.E, Agard, D.A.
Deposit date:	1995-09-06
Release date:	1996-01-29
Last modified:	2021-11-03
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity. J.Mol.Biol., 254, 1995

12 >

Total results:	30
Displayed results:	25
Sorted by:	Hit score (from highest)