Author results

1A28
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HORMONE-BOUND HUMAN PROGESTERONE RECEPTOR LIGAND-BINDING DOMAIN
Descriptor:PROGESTERONE RECEPTOR, PROGESTERONE
Authors:Sigler, P.B., Williams, S.P.
Deposit date:1998-01-19
Release date:1998-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Atomic structure of progesterone complexed with its receptor.
Nature, 393, 1998
1GOT
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HETEROTRIMERIC COMPLEX OF A GT-ALPHA/GI-ALPHA CHIMERA AND THE GT-BETA-GAMMA SUBUNITS
Descriptor:GT-ALPHA/GI-ALPHA CHIMERA, GT-BETA, GT-GAMMA, ...
Authors:Lambright, D.G., Sondek, J., Bohm, A., Skiba, N.P., Hamm, H.E., Sigler, P.B.
Deposit date:1996-08-07
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The 2.0 A crystal structure of a heterotrimeric G protein.
Nature, 379, 1996
1TBG
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BETA-GAMMA DIMER OF THE HETEROTRIMERIC G-PROTEIN TRANSDUCIN
Descriptor:TRANSDUCIN
Authors:Sondek, J.S., Bohm, A., Lambright, D.G., Hamm, H.E., Sigler, P.B.
Deposit date:1996-06-15
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a G-protein beta gamma dimer at 2.1A resolution.
Nature, 379, 1996
1WRP
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FLEXIBILITY OF THE DNA-BINDING DOMAINS OF TRP REPRESSOR
Descriptor:TRP REPRESSOR, TRYPTOPHAN
Authors:Schewitz, R.W., Otwinowski, Z., Lawson, C.L., Joachimiak, A.J., Sigler, P.B.
Deposit date:1987-12-01
Release date:1988-04-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Flexibility of the DNA-binding domains of trp repressor.
Proteins, 3, 1988
2OZ9
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E. COLI TRP HOLOREPRESSOR, ORTHORHOMBIC CRYSTAL FORM
Descriptor:Trp operon repressor, SODIUM ION, SULFATE ION, ...
Authors:Lawson, C.L., Sigler, P.B.
Deposit date:2007-02-25
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Flexibility of the DNA-binding domains of trp repressor.
Proteins, 3, 1988
3WRP
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FLEXIBILITY OF THE DNA-BINDING DOMAINS OF TRP REPRESSOR
Descriptor:TRP REPRESSOR
Authors:Zhang, R.-G., Sigler, P.B.
Deposit date:1987-12-01
Release date:1988-04-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Flexibility of the DNA-binding domains of trp repressor.
Proteins, 3, 1988
1C9B
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CRYSTAL STRUCTURE OF A HUMAN TBP CORE DOMAIN-HUMAN TFIIB CORE DOMAIN COMPLEX BOUND TO AN EXTENDED, MODIFIED ADENOVIRAL MAJOR LATE PROMOTER (ADMLP)
Descriptor:ADMLP TATA-BOX DNA CONTAINING IIB RECOGNITION ELEMENT, GENERAL TRANSCRIPTION FACTOR IIB, TATA BOX BINDING PROTEIN
Authors:Tsai, F.T.F., Sigler, P.B.
Deposit date:1999-08-01
Release date:2000-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis of preinitiation complex assembly on human pol II promoters.
EMBO J., 19, 2000
1PP2
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THE REFINED CRYSTAL STRUCTURE OF DIMERIC PHOSPHOLIPASE A2 AT 2.5 ANGSTROMS. ACCESS TO A SHIELDED CATALYTIC CENTER
Descriptor:CALCIUM-FREE PHOSPHOLIPASE A2
Authors:Brunie, S., Sigler, P.B.
Deposit date:1986-03-10
Release date:1986-05-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The refined crystal structure of dimeric phospholipase A2 at 2.5 A. Access to a shielded catalytic center.
J.Biol.Chem., 260, 1985
1B9Y
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STRUCTURAL ANALYSIS OF PHOSDUCIN AND ITS PHOSPHORYLATION-REGULATED INTERACTION WITH TRANSDUCIN BETA-GAMMA
Descriptor:PROTEIN (TRANSDUCIN), PROTEIN (PHOSDUCIN), GADOLINIUM ATOM
Authors:Gaudet, R., Sigler, P.B.
Deposit date:1999-02-16
Release date:1999-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin.
Mol.Cell, 3, 1999
1D3U
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TATA-BINDING PROTEIN/TRANSCRIPTION FACTOR (II)B/BRE+TATA-BOX COMPLEX FROM PYROCOCCUS WOESEI
Descriptor:DNA 24-MER: BRE+TATA-BOX, DNA 23-MER: BRE+TATA-BOX, TATA-BINDING PROTEIN, ...
Authors:Littlefield, O., Korkhin, Y., Sigler, P.B.
Deposit date:1999-10-01
Release date:1999-11-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structural basis for the oriented assembly of a TBP/TFB/promoter complex.
Proc.Natl.Acad.Sci.USA, 96, 1999
1TAD
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GTPASE MECHANISM OF GPROTEINS FROM THE 1.7-ANGSTROM CRYSTAL STRUCTURE OF TRANSDUCIN ALPHA-GDP-ALF4-
Descriptor:TRANSDUCIN-ALPHA, CALCIUM ION, CACODYLATE ION, ...
Authors:Sondek, J., Lambright, D.G., Noel, J.P., Hamm, H.E., Sigler, P.B.
Deposit date:1995-01-05
Release date:1995-05-08
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:GTPase mechanism of Gproteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4.
Nature, 372, 1994
1AON
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CRYSTAL STRUCTURE OF THE ASYMMETRIC CHAPERONIN COMPLEX GROEL/GROES/(ADP)7
Descriptor:GROEL, GROEL/GROES COMPLEX, MAGNESIUM ION, ...
Authors:Xu, Z., Horwich, A.L., Sigler, P.B.
Deposit date:1997-07-08
Release date:1997-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of the asymmetric GroEL-GroES-(ADP)7 chaperonin complex.
Nature, 388, 1997
1B9X
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STRUCTURAL ANALYSIS OF PHOSDUCIN AND ITS PHOSPHORYLATION-REGULATED INTERACTION WITH TRANSDUCIN
Descriptor:PROTEIN (TRANSDUCIN), PROTEIN (PHOSDUCIN), GADOLINIUM ATOM
Authors:Gaudet, R., Sigler, P.B.
Deposit date:1999-02-16
Release date:1999-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin.
Mol.Cell, 3, 1999
1POA
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INTERFACIAL CATALYSIS: THE MECHANISM OF PHOSPHOLIPASE A2
Descriptor:PHOSPHOLIPASE A2, CALCIUM ION
Authors:Scott, D.L., Otwinowski, Z., Sigler, P.B.
Deposit date:1992-09-07
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Interfacial catalysis: the mechanism of phospholipase A2.
Science, 250, 1990
1POB
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CRYSTAL STRUCTURE OF COBRA-VENOM PHOSPHOLIPASE A2 IN A COMPLEX WITH A TRANSITION-STATE ANALOGUE
Descriptor:PHOSPHOLIPASE A2, CALCIUM ION, 1-O-OCTYL-2-HEPTYLPHOSPHONYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
Authors:White, S.P., Scott, D.L., Otwinowski, Z., Sigler, P.B.
Deposit date:1992-09-07
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of cobra-venom phospholipase A2 in a complex with a transition-state analogue.
Science, 250, 1990
1POC
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CRYSTAL STRUCTURE OF BEE-VENOM PHOSPHOLIPASE A2 IN A COMPLEX WITH A TRANSITION-STATE ANALOGUE
Descriptor:PHOSPHOLIPASE A2, CALCIUM ION, 1-O-OCTYL-2-HEPTYLPHOSPHONYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
Authors:Scott, D.L., Otwinowski, Z., Sigler, P.B.
Deposit date:1992-09-07
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of bee-venom phospholipase A2 in a complex with a transition-state analogue.
Science, 250, 1990
1POE
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STRUCTURES OF FREE AND INHIBITED HUMAN SECRETORY PHOSPHOLIPASE A2 FROM INFLAMMATORY EXUDATE
Descriptor:PHOSPHOLIPASE A2, CALCIUM ION, 1-O-OCTYL-2-HEPTYLPHOSPHONYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
Authors:Scott, D.L., White, S.P., Sigler, P.B.
Deposit date:1992-09-07
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of free and inhibited human secretory phospholipase A2 from inflammatory exudate.
Science, 254, 1991
1R4O
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CRYSTALLOGRAPHIC ANALYSIS OF THE INTERACTION OF THE GLUCOCORTICOID RECEPTOR WITH DNA
Descriptor:5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*GP*AP*TP*GP*TP*TP*CP*TP*G)-3', Glucocorticoid receptor, ZINC ION
Authors:Luisi, B.F., Xu, W.X., Otwinowski, Z., Freedman, L.P., Yamamoto, K.R., Sigler, P.B.
Deposit date:2003-10-07
Release date:2003-10-21
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic Analysis of the Interaction of The Glucocorticoid Receptor with DNA
Nature, 352, 1991
1TAG
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STRUCTURAL DETERMINANTS FOR ACTIVATION OF THE ALPHA-SUBUNIT OF A HETEROTRIMERIC G PROTEIN
Descriptor:TRANSDUCIN-ALPHA, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Lambright, D.G., Noel, J.P., Hamm, H.E., Sigler, P.B.
Deposit date:1994-11-23
Release date:1995-02-07
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein.
Nature, 369, 1994
1TRO
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CRYSTAL STRUCTURE OF TRP REPRESSOR OPERATOR COMPLEX AT ATOMIC RESOLUTION
Descriptor:DNA (5'-D(*TP*GP*TP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*TP*AP*GP*T P*AP*C)-3'), PROTEIN (TRP REPRESSOR), TRYPTOPHAN
Authors:Otwinowski, Z., Schevitz, R.W., Zhang, R.-G., Lawson, C.L., Joachimiak, A.J., Marmorstein, R., Luisi, B.F., Sigler, P.B.
Deposit date:1992-08-30
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of trp repressor/operator complex at atomic resolution.
Nature, 335, 1988
1YFG
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YEAST INITIATOR TRNA
Descriptor:YEAST INITIATOR TRNA
Authors:Basavappa, R., Sigler, P.B.
Deposit date:1997-05-08
Release date:1997-09-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The 3 A crystal structure of yeast initiator tRNA: functional implications in initiator/elongator discrimination.
EMBO J., 10, 1991
2TRC
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PHOSDUCIN/TRANSDUCIN BETA-GAMMA COMPLEX
Descriptor:TRANSDUCIN, PHOSDUCIN, GADOLINIUM ATOM
Authors:Gaudet, R., Bohm, A., Sigler, P.B.
Deposit date:1997-01-06
Release date:1997-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin.
Cell(Cambridge,Mass.), 87, 1996
1A52
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ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN COMPLEXED TO ESTRADIOL
Descriptor:ESTROGEN RECEPTOR, ESTRADIOL, GOLD ION
Authors:Tanenbaum, D.M., Wang, Y., Sigler, P.B.
Deposit date:1998-02-19
Release date:1998-09-16
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains.
Proc.Natl.Acad.Sci.USA, 95, 1998
1AIP
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EF-TU EF-TS COMPLEX FROM THERMUS THERMOPHILUS
Descriptor:ELONGATION FACTOR TU, ELONGATION FACTOR TS
Authors:Wang, Y., Jiang, Y., Meyering-Voss, M., Sprinzl, M., Sigler, P.B.
Deposit date:1997-04-22
Release date:1997-10-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the EF-Tu.EF-Ts complex from Thermus thermophilus.
Nat.Struct.Biol., 4, 1997
1AIS
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TATA-BINDING PROTEIN/TRANSCRIPTION FACTOR (II)B/TATA-BOX COMPLEX FROM PYROCOCCUS WOESEI
Descriptor:DNA (5'-D(*AP*AP*CP*TP*TP*AP*CP*TP*TP*TP*(5IU)P*(5IU)P*AP*AP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*TP*TP*AP*AP*AP*AP*AP*GP*TP*AP*AP*GP*TP*T )-3'), PROTEIN (TATA-BINDING PROTEIN), ...
Authors:Kosa, P.F., Ghosh, G., Dedecker, B.S., Sigler, P.B.
Deposit date:1997-04-24
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The 2.1-A crystal structure of an archaeal preinitiation complex: TATA-box-binding protein/transcription factor (II)B core/TATA-box.
Proc.Natl.Acad.Sci.USA, 94, 1997