Author results

1TQ9
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NON-COVALENT SWAPPED DIMER OF BOVINE SEMINAL RIBONUCLEASE IN COMPLEX WITH 2'-DEOXYCYTIDINE-2'-DEOXYADENOSINE-3',5'-MONOPHOSPHATE
Descriptor:Ribonuclease, seminal, 2'-DEOXYCYTIDINE-2'-DEOXYADENOSINE-3',5'-MONOPHOSPHATE
Authors:Sica, F., Di Fiore, A., Merlino, A., Mazzarella, L.
Deposit date:2004-06-17
Release date:2004-09-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and Stability of the Non-covalent Swapped Dimer of Bovine Seminal Ribonuclease: AN ENZYME TAILORED TO EVADE RIBONUCLEASE PROTEIN INHIBITOR
J.Biol.Chem., 279, 2004
1N3Z
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CRYSTAL STRUCTURE OF THE [S-CARBOXYAMIDOMETHYL-CYS31, S-CARBOXYAMIDOMETHYL-CYS32] MONOMERIC DERIVATIVE OF THE BOVINE SEMINAL RIBONUCLEASE IN THE LIGANDED STATE
Descriptor:Ribonuclease, seminal, 3'-URIDINEMONOPHOSPHATE, ...
Authors:Sica, F., Di Fiore, A., Zagari, A., Mazzarella, L.
Deposit date:2002-10-30
Release date:2003-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The unswapped chain of bovine seminal ribonuclease: Crystal structure of the free and liganded monomeric derivative
Proteins, 52, 2003
1N1X
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CRYSTAL STRUCTURE ANALYSIS OF THE MONOMERIC [S-CARBOXYAMIDOMETHYL-CYS31, S-CARBOXYAMIDOMETHYL-CYS32] BOVINE SEMINAL RIBONUCLEASE
Descriptor:Ribonuclease, seminal
Authors:Sica, F., Di Fiore, A., Zagari, A., Mazzarella, L.
Deposit date:2002-10-21
Release date:2003-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The unswapped chain of bovine seminal ribonuclease: Crystal structure of the free and liganded monomeric derivative
Proteins, 52, 2003
2EFF
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CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX BETWEEN CYAY AND CO(II)
Descriptor:Protein cyaY, COBALT (II) ION
Authors:Sica, F., Franzese, M.
Deposit date:2007-02-22
Release date:2007-10-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Understanding the binding properties of an unusual metal-binding protein - a study of bacterial frataxin
Febs J., 274, 2007
2P1X
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CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX BETWEEN CYAY AND EU(III)
Descriptor:Protein cyaY, EUROPIUM (III) ION
Authors:Sica, F., Franzese, M.
Deposit date:2007-03-06
Release date:2007-10-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Understanding the binding properties of an unusual metal-binding protein-a study of bacterial frataxin
Febs J., 274, 2007
4N4C
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CRYSTAL STRUCTURE OF THE C-TERMINAL SWAPPED DIMER OF A BOVINE SEMINAL RIBONUCLEASE MUTANT
Descriptor:Seminal ribonuclease, PHOSPHATE ION
Authors:Pica, A., Russo Krauss, I., Merlino, A., Sica, F.
Deposit date:2013-10-08
Release date:2013-11-06
Last modified:2013-12-04
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:The multiple forms of bovine seminal ribonuclease: Structure and stability of a C-terminal swapped dimer.
Febs Lett., 587, 2013
1Y92
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CRYSTAL STRUCTURE OF THE P19A/N67D VARIANT OF BOVINE SEMINAL RIBONUCLEASE
Descriptor:Seminal ribonuclease
Authors:Picone, D., Di Fiore, A., Ercole, C., Franzese, M., Sica, F., Tomaselli, S., Mazzarella, L.
Deposit date:2004-12-14
Release date:2004-12-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Role of the Hinge Loop in Domain Swapping: THE SPECIAL CASE OF BOVINE SEMINAL RIBONUCLEASE.
J.Biol.Chem., 280, 2005
1Y94
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CRYSTAL STRUCTURE OF THE G16S/N17T/P19A/S20A/N67D VARIANT OF BOVINE SEMINAL RIBONUCLEASE
Descriptor:Seminal ribonuclease
Authors:Picone, D., Di Fiore, A., Ercole, C., Franzese, M., Sica, F., Tomaselli, S., Mazzarella, L.
Deposit date:2004-12-14
Release date:2004-12-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Role of the Hinge Loop in Domain Swapping: THE SPECIAL CASE OF BOVINE SEMINAL RIBONUCLEASE.
J.Biol.Chem., 280, 2005
3BCM
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CRYSTAL STRUCTURE OF THE UNSWAPPED FORM OF P19A/L28Q/N67D BS-RNASE
Descriptor:Seminal ribonuclease, PHOSPHATE ION
Authors:Merlino, A., Ercole, C., Picone, D., Pizzo, E., Mazzarella, L., Sica, F.
Deposit date:2007-11-13
Release date:2008-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme
J.Mol.Biol., 376, 2008
3BCO
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CRYSTAL STRUCTURE OF THE SWAPPED FORM OF P19A/L28Q/N67D BS-RNASE
Descriptor:Seminal ribonuclease
Authors:Merlino, A., Ercole, C., Picone, D., Pizzo, E., Mazzarella, L., Sica, F.
Deposit date:2007-11-13
Release date:2008-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme
J.Mol.Biol., 376, 2008
3BCP
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CRYSTAL STRUCTURE OF THE SWAPPED NON COVALENT FORM OF P19A/L28Q/N67D BS-RNASE
Descriptor:Seminal ribonuclease
Authors:Merlino, A., Ercole, C., Picone, D., Pizzo, E., Mazzarella, L., Sica, F.
Deposit date:2007-11-13
Release date:2008-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme
J.Mol.Biol., 376, 2008
11BG
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A POTENTIAL ALLOSTERIC SUBSITE GENERATED BY DOMAIN SWAPPING IN BOVINE SEMINAL RIBONUCLEASE
Descriptor:PROTEIN (BOVINE SEMINAL RIBONUCLEASE), SULFATE ION, URIDYLYL-2'-5'-PHOSPHO-GUANOSINE
Authors:Vitagliano, L., Adinolfi, S., Sica, F., Merlino, A., Zagari, A., Mazzarella, L.
Deposit date:1999-03-11
Release date:1999-11-05
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A potential allosteric subsite generated by domain swapping in bovine seminal ribonuclease.
J.Mol.Biol., 293, 1999
1R5C
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X-RAY STRUCTURE OF THE COMPLEX OF BOVINE SEMINAL RIBONUCLEASE SWAPPING DIMER WITH D(CPA)
Descriptor:Ribonuclease, seminal, 2'-DEOXYCYTIDINE-2'-DEOXYADENOSINE-3',5'-MONOPHOSPHATE
Authors:Merlino, A., Vitagliano, L., Sica, F., Zagari, A., Mazzarella, L.
Deposit date:2003-10-10
Release date:2004-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Population shift vs induced fit: The case of bovine seminal ribonuclease swapping dimer
Biopolymers, 73, 2004
1R5D
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X-RAY STRUCTURE OF BOVINE SEMINAL RIBONUCLEASE SWAPPING DIMER FROM A NEW CRYSTAL FORM
Descriptor:Ribonuclease, seminal
Authors:Merlino, A., Vitagliano, L., Sica, F., Zagari, A., Mazzarella, L.
Deposit date:2003-10-10
Release date:2004-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Population shift vs induced fit: The case of bovine seminal ribonuclease swapping dimer
Biopolymers, 73, 2004
1R37
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ALCOHOL DEHYDROGENASE FROM SULFOLOBUS SOLFATARICUS COMPLEXED WITH NAD(H) AND 2-ETHOXYETHANOL
Descriptor:NAD-dependent alcohol dehydrogenase, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Esposito, L., Bruno, I., Sica, F., Raia, C.A., Giordano, A., Rossi, M., Mazzarella, L., Zagari, A.
Deposit date:2003-09-30
Release date:2004-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a ternary complex of the alcohol dehydrogenase from Sulfolobus solfataricus
Biochemistry, 42, 2003
1YV4
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X-RAY STRUCTURE OF M23L ONCONASE AT 100K
Descriptor:P-30 protein, SULFATE ION
Authors:Merlino, A., Mazzarella, L., Carannante, A., Di Fiore, A., Di Donato, A., Notomista, E., Sica, F.
Deposit date:2005-02-15
Release date:2005-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:The Importance of Dynamic Effects on the Enzyme Activity: X-RAY STRUCTURE AND MOLECULAR DYNAMICS OF ONCONASE MUTANTS
J.Biol.Chem., 280, 2005
1YV6
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X-RAY STRUCTURE OF M23L ONCONASE AT 298K
Descriptor:P-30 protein, SULFATE ION
Authors:Merlino, A., Mazzarella, L., Carannante, A., Di Fiore, A., Di Donato, A., Notomista, E., Sica, F.
Deposit date:2005-02-15
Release date:2005-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:The Importance of Dynamic Effects on the Enzyme Activity: X-RAY STRUCTURE AND MOLECULAR DYNAMICS OF ONCONASE MUTANTS
J.Biol.Chem., 280, 2005
1YV7
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X-RAY STRUCTURE OF (C87S,DES103-104) ONCONASE
Descriptor:P-30 protein, SULFATE ION
Authors:Merlino, A., Mazzarella, L., Carannante, A., Di Fiore, A., Di Donato, A., Notomista, E., Sica, F.
Deposit date:2005-02-15
Release date:2005-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Importance of Dynamic Effects on the Enzyme Activity: X-RAY STRUCTURE AND MOLECULAR DYNAMICS OF ONCONASE MUTANTS
J.Biol.Chem., 280, 2005
3F8G
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THE X-RAY STRUCTURE OF A DIMERIC VARIANT OF HUMAN PANCREATIC RIBONUCLEASE WITH HIGH CYTOTOXIC AND ANTITUMOR ACTIVITIES
Descriptor:Ribonuclease pancreatic, SULFATE ION
Authors:Merlino, A., Avella, G., Mazzarella, L., Sica, F.
Deposit date:2008-11-12
Release date:2009-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant.
Protein Sci., 18, 2009
3FKZ
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X-RAY STRUCTURE OF THE NON COVALENT SWAPPED FORM OF THE S16G/T17N/A19P/A20S/K31C/S32C MUTANT OF BOVINE PANCREATIC RIBONUCLEASE
Descriptor:Ribonuclease pancreatic
Authors:Merlino, A., Russo Krauss, I., Perillo, M., Mattia, C.A., Ercole, C., Picone, D., Vergara, A., Sica, F.
Deposit date:2008-12-18
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Toward an antitumor form of bovine pancreatic ribonuclease: The crystal structure of three noncovalent dimeric mutants
Biopolymers, 91, 2009
3FL0
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X-RAY STRUCTURE OF THE NON COVALENT SWAPPED FORM OF THE Q28L/K31C/S32C MUTANT OF BOVINE PANCREATIC RIBONUCLEASE IN COMPLEX WITH 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE
Descriptor:Ribonuclease pancreatic, 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE
Authors:Merlino, A., Russo Krauss, I., Perillo, M., Mattia, C.A., Ercole, C., Picone, D., Vergara, A., Sica, F.
Deposit date:2008-12-18
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Toward an antitumor form of bovine pancreatic ribonuclease: The crystal structure of three noncovalent dimeric mutants
Biopolymers, 91, 2009
3FL1
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X-RAY STRUCTURE OF THE NON COVALENT SWAPPED FORM OF THE A19P/Q28L/K31C/S32C MUTANT OF BOVINE PANCREATIC RIBONUCLEASE IN COMPLEX WITH 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE
Descriptor:Ribonuclease pancreatic, TREHALOSE, 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE, ...
Authors:Merlino, A., Russo Krauss, I., Perillo, M., Mattia, C.A., Ercole, C., Picone, D., Vergara, A., Sica, F.
Deposit date:2008-12-18
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Toward an antitumor form of bovine pancreatic ribonuclease: The crystal structure of three noncovalent dimeric mutants
Biopolymers, 91, 2009
3FL3
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X-RAY STRUCTURE OF THE LIGAND FREE NON COVALENT SWAPPED FORM OF THE A19P/Q28L/K31C/S32C MUTANT OF BOVINE PANCREATIC RIBONUCLEASE
Descriptor:Ribonuclease pancreatic, TREHALOSE
Authors:Merlino, A., Russo Krauss, I., Perillo, M., Mattia, C.A., Ercole, C., Picone, D., Vergara, A., Sica, F.
Deposit date:2008-12-18
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Toward an antitumor form of bovine pancreatic ribonuclease: The crystal structure of three noncovalent dimeric mutants
Biopolymers, 91, 2009
4I7Y
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CRYSTAL STRUCTURE OF HUMAN ALPHA THROMBIN IN COMPLEX WITH A 27-MER APTAMER BOUND TO EXOSITE II
Descriptor:Prothrombin, DNA (27-MER), D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ...
Authors:Pica, A., Russo Krauss, I., Merlino, A., Mazzarella, L., Sica, F.
Deposit date:2012-12-01
Release date:2013-10-16
Last modified:2014-01-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Duplex-quadruplex motifs in a peculiar structural organization cooperatively contribute to thrombin binding of a DNA aptamer.
Acta Crystallogr.,Sect.D, 69, 2013
5EW1
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HUMAN THROMBIN SANDWICHED BETWEEN TWO DNA APTAMERS: HD22 AND HD1-DELTAT3
Descriptor:thrombin light chain, Thrombin heavy chain, HD22 (27mer), ...
Authors:Pica, A., Russo Krauss, I., Parente, V., Sica, F.
Deposit date:2015-11-20
Release date:2016-11-30
Last modified:2017-01-18
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers.
Nucleic Acids Res., 45, 2017
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