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5F8J
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BU of 5f8j by Molmil
Enterovirus 71 Polymerase Elongation Complex (C1S4 Form)
Descriptor: GLYCEROL, Genome polyprotein, MAGNESIUM ION, ...
Authors:Shu, B, Gong, P.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.675 Å)
Cite:Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5F8L
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BU of 5f8l by Molmil
Enterovirus 71 Polymerase Elongation Complex (C3S1 Form)
Descriptor: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ...
Authors:Shu, B, Gong, P.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.812 Å)
Cite:Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5F8H
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BU of 5f8h by Molmil
Enterovirus 71 Polymerase Elongation Complex (C1S1/2 Form)
Descriptor: Genome polyprotein, MAGNESIUM ION, RNA (35-MER), ...
Authors:Shu, B, Gong, P.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5F8G
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BU of 5f8g by Molmil
Enterovirus 71 Polymerase Elongation Complex (C1S1 Form)
Descriptor: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), ...
Authors:Shu, B, Gong, P.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5F8N
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BU of 5f8n by Molmil
Enterovirus 71 Polymerase Elongation Complex (C3S6 Form)
Descriptor: GLYCEROL, Genome polyprotein, PYROPHOSPHATE 2-, ...
Authors:Shu, B, Gong, P.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.484 Å)
Cite:Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5F8I
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BU of 5f8i by Molmil
Enterovirus 71 Polymerase Elongation Complex (C1S2/3 Form)
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, GLYCEROL, Genome polyprotein, ...
Authors:Shu, B, Gong, P.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5F8M
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BU of 5f8m by Molmil
Enterovirus 71 Polymerase Elongation Complex (C3S4/5 Form)
Descriptor: GLYCEROL, Genome polyprotein, MAGNESIUM ION, ...
Authors:Shu, B, Gong, P.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
7WUV
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BU of 7wuv by Molmil
CryoEM structure of sNS1 hexamer
Descriptor: Core protein
Authors:Shu, B, Ooi, J.S.G, Lok, S.M.
Deposit date:2022-02-09
Release date:2022-12-21
Method:ELECTRON MICROSCOPY (8 Å)
Cite:CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
7WUS
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BU of 7wus by Molmil
CryoEM structure of a dimer of loose sNS1 tetramer
Descriptor: Core protein
Authors:Shu, B, Lok, S.M.
Deposit date:2022-02-09
Release date:2022-12-21
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
7WUT
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BU of 7wut by Molmil
CryoEM structure of stable sNS1 tetramer
Descriptor: Core protein
Authors:Shu, B, Ooi, J.S.G, Lok, S.M.
Deposit date:2022-02-09
Release date:2022-12-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
7WUR
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BU of 7wur by Molmil
CryoEM structure of sNS1 complexed with Fab5E3
Descriptor: Core protein, Fab 5E3 Heavy Chain, Fab 5E3 Light Chain
Authors:Shu, B, Lok, S.M.
Deposit date:2022-02-09
Release date:2022-12-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
7WUU
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BU of 7wuu by Molmil
CryoEM structure of loose sNS1 tetramer
Descriptor: Core protein
Authors:Shu, B, Lok, S.M.
Deposit date:2022-02-09
Release date:2022-12-21
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (8.3 Å)
Cite:CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
7YAR
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BU of 7yar by Molmil
ZIKV_Fab_G9E
Descriptor: E protein, M protein, heavy chain, ...
Authors:Shu, B, Thiam-Seng, N, Lok, S.
Deposit date:2022-06-28
Release date:2023-01-04
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus.
Plos Pathog., 19, 2023
7V3F
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BU of 7v3f by Molmil
DENV2_NGC_Fab_C10 28degree (1Fab:3E)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ...
Authors:Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M.
Deposit date:2021-08-10
Release date:2021-12-29
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
7V3J
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BU of 7v3j by Molmil
DENV2:F(ab')2-local
Descriptor: Envelope protein E, Fab_C10_heavy_chain, Fab_C10_light_chain, ...
Authors:Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M.
Deposit date:2021-08-10
Release date:2021-12-29
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
7V3G
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BU of 7v3g by Molmil
DENV2_NGC_Fab_C10 28degrees (2Fab:3E)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ...
Authors:Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M.
Deposit date:2021-08-10
Release date:2021-12-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
7V3I
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BU of 7v3i by Molmil
DENV2_NGC_Fab_C10 4degrees (3Fab:3E)
Descriptor: Envelope protein E, Fab_C10_heavy_chain, Fab_C10_light_chain, ...
Authors:Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M.
Deposit date:2021-08-10
Release date:2021-12-29
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
7V3H
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BU of 7v3h by Molmil
DENV2_NGC_Fab_C10 28degrees (3Fab:3E)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C10 IgG heavy chain variable region, ...
Authors:Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M.
Deposit date:2021-08-10
Release date:2021-12-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
7CW3
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BU of 7cw3 by Molmil
Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG (subregion around icosahedral 2-fold vertex)
Descriptor: Capsid protein, E1 glycoprotein, E2 glycoprotein, ...
Authors:Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M.
Deposit date:2020-08-27
Release date:2020-11-04
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
7CW0
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BU of 7cw0 by Molmil
Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG
Descriptor: Capsid protein, E1 glycoprotein, E2 glycoprotein, ...
Authors:Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M.
Deposit date:2020-08-27
Release date:2020-11-04
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
5Y6Z
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BU of 5y6z by Molmil
Crystal structure of the coxsackievirus A16 polymerase elongation complex
Descriptor: GLYCEROL, Genome polyprotein, MAGNESIUM ION, ...
Authors:Bi, P, Shu, B, Gong, P.
Deposit date:2017-08-15
Release date:2017-12-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the coxsackievirus A16 RNA-dependent RNA polymerase elongation complex reveals novel features in motif A dynamics
Virol Sin, 32, 2017
6LSE
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BU of 6lse by Molmil
Crystal structure of the enterovirus 71 polymerase elongation complex (C3S6A/C3S6B form)
Descriptor: Genome polyprotein, PYROPHOSPHATE 2-, RNA (35-MER), ...
Authors:Wang, M, Shu, B, Jing, X, Gong, P.
Deposit date:2020-01-17
Release date:2020-04-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures.
Nat Commun, 11, 2020
6LSF
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BU of 6lsf by Molmil
Crystal structure of the enterovirus 71 polymerase elongation complex (C2S6RA/C2S6RB form)
Descriptor: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ...
Authors:Wang, M, Shu, B, Jing, X, Gong, P.
Deposit date:2020-01-17
Release date:2020-04-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.152 Å)
Cite:Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures.
Nat Commun, 11, 2020
7CW2
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BU of 7cw2 by Molmil
Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-263 (subregion around icosahedral 5-fold vertex)
Descriptor: Capsid protein, E1 glycoprotein, E2 glycoprotein, ...
Authors:Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M.
Deposit date:2020-08-27
Release date:2020-11-04
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
7CVZ
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BU of 7cvz by Molmil
Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-263
Descriptor: Capsid protein, E1 glycoprotein, E2 glycoprotein, ...
Authors:Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M.
Deposit date:2020-08-27
Release date:2020-11-04
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020

 

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