Author results

2O5K
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CRYSTAL STRUCTURE OF GSK3BETA IN COMPLEX WITH A BENZOIMIDAZOL INHIBITOR
Descriptor:Glycogen synthase kinase-3 beta, 2-(2,4-DICHLORO-PHENYL)-7-HYDROXY-1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID [2-(4-METHANESULFONYLAMINO-PHENYL)-ETHYL]-AMIDE
Authors:Shin, D., Lee, S.C., Heo, Y.S., Cho, Y.S., Kim, Y.E., Hyun, Y.L., Cho, J.M., Lee, Y.S., Ro, S.
Deposit date:2006-12-06
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Design and synthesis of 7-hydroxy-1H-benzoimidazole derivatives as novel inhibitors of glycogen synthase kinase-3beta
Bioorg.Med.Chem.Lett., 17, 2007
2HJW
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CRYSTAL STRUCTURE OF THE BC DOMAIN OF ACC2
Descriptor:Acetyl-CoA carboxylase 2
Authors:Cho, Y.S., Lee, J.I., Shin, D., Kim, H.T., Lee, T.G., Heo, Y.S.
Deposit date:2006-07-02
Release date:2007-07-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the biotin carboxylase domain of human acetyl-CoA carboxylase 2.
Proteins, 70, 2008
3JRW
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PHOSPHORYLATED BC DOMAIN OF ACC2
Descriptor:Acetyl-CoA carboxylase 2
Authors:Cho, Y.S., Lee, J.I., Shin, D., Kim, H.T., Lee, T.G., Heo, Y.S.
Deposit date:2009-09-09
Release date:2010-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK
Biochem.Biophys.Res.Commun., 391, 2010
3JRX
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CRYSTAL STRUCTURE OF THE BC DOMAIN OF ACC2 IN COMPLEX WITH SORAPHEN A
Descriptor:Acetyl-CoA carboxylase 2, SORAPHEN A
Authors:Cho, Y.S., Lee, J.I., Shin, D., Kim, H.T., Lee, T.G., Heo, Y.S.
Deposit date:2009-09-09
Release date:2010-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK.
Biochem.Biophys.Res.Commun., 391, 2010
4LFU
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI SDIA IN THE SPACE GROUP C2
Descriptor:Regulatory protein SdiA, TETRAETHYLENE GLYCOL, CHLORIDE ION
Authors:Kim, T., Duong, T., Wu, C.A., Choi, J., Lan, N., Kang, S.W., Lokanath, N.K., Shin, D., Hwang, H.Y., Kim, K.K.
Deposit date:2013-06-27
Release date:2014-03-19
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor
Acta Crystallogr.,Sect.D, 70, 2014
4LGW
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI SDIA IN THE SPACE GROUP P6522
Descriptor:Regulatory protein SdiA, GLYCEROL
Authors:Kim, T., Duong, T., Wu, C.A., Choi, J., Lan, N., Kang, S.W., Lokanath, N.K., Shin, D., Hwang, H.Y., Kim, K.K.
Deposit date:2013-06-28
Release date:2014-03-19
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor
Acta Crystallogr.,Sect.D, 70, 2014
4ZQS
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NEW COMPACT CONFORMATION OF LINEAR UB2 STRUCTURE
Descriptor:ubiquitin
Authors:Thach, T.T., Shin, D., Han, S., Lee, S.
Deposit date:2015-05-11
Release date:2016-04-20
Method:X-RAY DIFFRACTION (1.804 Å)
Cite:New conformations of linear polyubiquitin chains from crystallographic and solution-scattering studies expand the conformational space of polyubiquitin.
Acta Crystallogr D Struct Biol, 72, 2016
4Q9D
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X-RAY STRUCTURE OF A PUTATIVE THIAMIN DIPHOSPHATE-DEPENDENT ENZYME ISOLATED FROM MYCOBACTERIUM SMEGMATIS
Descriptor:Benzoylformate decarboxylase, MAGNESIUM ION, FORMIC ACID
Authors:Andrews, F.H., Horton, J.D., Yoon, H.J., Malik, A.M.K., Logsdon, M.G., Shin, D.H., Kneen, M.M., Suh, S.W., McLeish, M.J.
Deposit date:2014-04-30
Release date:2015-04-29
Last modified:2015-06-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The kinetic characterization and X-ray structure of a putative benzoylformate decarboxylase from M. smegmatis highlights the difficulties in the functional annotation of ThDP-dependent enzymes.
Biochim.Biophys.Acta, 1854, 2015
4KMF
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CRYSTAL STRUCTURE OF ZALPHA DOMAIN FROM CARASSIUS AURATUS PKZ IN COMPLEX WITH Z-DNA
Descriptor:Interferon-inducible and double-stranded-dependent eIF-2kinase, DNA (5'-D(*TP*CP*GP*CP*GP*CP*G)-3'), MANGANESE (II) ION
Authors:Kim, D., Kim, K.K.
Deposit date:2013-05-08
Release date:2013-07-03
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Distinct Z-DNA binding mode of a PKR-like protein kinase containing a Z-DNA binding domain (PKZ).
Nucleic Acids Res., 42, 2014
5ZU1
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CRYSTAL STRUCTURE OF BZ JUNCTION IN DIVERSE SEQUENCE
Descriptor:Double-stranded RNA-specific adenosine deaminase, DNA (5'-D(*GP*TP*CP*GP*CP*GP*CP*GP*CP*CP*TP*TP*AP*AP*AP*CP*C)-3'), DNA (5'-D(*AP*CP*GP*GP*TP*TP*TP*AP*AP*GP*GP*CP*GP*CP*GP*CP*G)-3')
Authors:Kim, K.K., Kim, D.
Deposit date:2018-05-05
Release date:2018-08-29
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (3.009 Å)
Cite:Sequence preference and structural heterogeneity of BZ junctions.
Nucleic Acids Res., 46, 2018
5ZUO
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CRYSTAL STRUCTURE OF BZ JUNCTION IN DIVERSE SEQUENCE
Descriptor:Double-stranded RNA-specific adenosine deaminase, DNA (5'-D(*GP*TP*CP*GP*CP*GP*CP*GP*CP*GP*AP*TP*AP*AP*AP*CP*C)-3'), DNA (5'-D(*AP*CP*GP*GP*TP*TP*TP*AP*TP*CP*GP*CP*GP*CP*GP*CP*G)-3')
Authors:Kim, K.K., Kim, D.
Deposit date:2018-05-08
Release date:2018-08-29
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.902 Å)
Cite:Sequence preference and structural heterogeneity of BZ junctions.
Nucleic Acids Res., 46, 2018
5ZUP
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CRYSTAL STRUCTURE OF BZ JUNCTION IN DIVERSE SEQUENCE
Descriptor:Double-stranded RNA-specific adenosine deaminase, (5'-D(*GP*TP*CP*GP*CP*GP*CP*GP*CP*AP*AP*TP*AP*AP*AP*CP*C)-3'), (5'-D(*AP*CP*GP*GP*TP*TP*TP*AP*TP*CP*GP*CP*GP*CP*GP*CP*G)-3')
Authors:Kim, K.K., Kim, D.
Deposit date:2018-05-08
Release date:2018-08-29
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Sequence preference and structural heterogeneity of BZ junctions.
Nucleic Acids Res., 46, 2018
1L8L
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MOLECULAR BASIS FOR THE LOCAL CONFOMATIONAL REARRANGEMENT OF HUMAN PHOSPHOSERINE PHOSPHATASE
Descriptor:L-3-phosphoserine phosphatase, D-2-AMINO-3-PHOSPHONO-PROPIONIC ACID
Authors:Kim, H.Y., Heo, Y.S., Kim, J.H., Park, M.H., Moon, J., Park, S.Y., Lee, T.G., Jeon, Y.H., Ro, S., Hwang, K.Y.
Deposit date:2002-03-21
Release date:2003-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase.
J.Biol.Chem., 277, 2002
1L8O
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MOLECULAR BASIS FOR THE LOCAL CONFORMATIONAL REARRANGEMENT OF HUMAN PHOSPHOSERINE PHOSPHATASE
Descriptor:L-3-phosphoserine phosphatase, PHOSPHATE ION, SERINE
Authors:Kim, H.Y., Heo, Y.S., Kim, J.H., Park, M.H., Moon, J., Park, S.Y., Lee, T.G., Jeon, Y.H., Ro, S., Hwang, K.Y.
Deposit date:2002-03-21
Release date:2003-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase
J.Biol.Chem., 277, 2002
1M4H
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CRYSTAL STRUCTURE OF BETA-SECRETASE COMPLEXED WITH INHIBITOR OM00-3
Descriptor:beta-Secretase, Inhibitor OM00-3
Authors:Hong, L., Turner, R.T., Koelsch, G., Ghosh, A.K., Tang, J.
Deposit date:2002-07-02
Release date:2002-08-28
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Memapsin 2 (beta-Secretase) in Complex with Inhibitor OM00-3
Biochemistry, 41, 2002
4OWI
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PEPTIDE STRUCTURE
Descriptor:p53LZ2
Authors:Lee, J.-H.
Deposit date:2014-02-02
Release date:2014-05-21
Last modified:2015-01-14
Method:X-RAY DIFFRACTION (1.202 Å)
Cite:Protein grafting of p53TAD onto a leucine zipper scaffold generates a potent HDM dual inhibitor.
Nat Commun, 5, 2014
5GWO
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CRYSTAL STRUCTURE OF RCAR3:PP2C S265F/I267M WITH (+)-ABA
Descriptor:Probable protein phosphatase 2C 50, ABA receptor RCAR3, MAGNESIUM ION, ...
Authors:Han, S., Lee, S.
Deposit date:2016-09-12
Release date:2017-09-13
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.816 Å)
Cite:Modulation of ABA Signaling by Altering VxG Phi L Motif of PP2Cs in Oryza sativa.
Mol Plant, 10, 2017
5GWP
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CRYSTAL STRUCTURE OF RCAR3:PP2C WILD-TYPE WITH (+)-ABA
Descriptor:Probable protein phosphatase 2C 50, ABA receptor RCAR3, MAGNESIUM ION, ...
Authors:Han, S., Lee, S.
Deposit date:2016-09-12
Release date:2017-09-13
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.577 Å)
Cite:Modulation of ABA Signaling by Altering VxG Phi L Motif of PP2Cs in Oryza sativa.
Mol Plant, 10, 2017
6G0C
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CRYSTAL STRUCTURE OF SDEA CATALYTIC CORE
Descriptor:Ubiquitinating/deubiquitinating enzyme SdeA, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, 1,2-ETHANEDIOL
Authors:Kalayil, S., Bhogaraju, S., Basquin, J., Dikic, I.
Deposit date:2018-03-17
Release date:2018-05-30
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination.
Nature, 557, 2018