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1IYO
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TOHO-1 BETA-LACTAMASE IN COMPLEX WITH CEFOTAXIME
分子名称:Toho-1 beta-lactamase, SULFATE ION, CEFOTAXIME, ...
著者Shimamura, T., Ibuka, A., Fushinobu, S., Wakagi, T., Ishiguro, M., Ishii, Y., Matsuzawa, H.
登録日2002-09-04
公開日2002-12-11
最終更新日2017-03-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Acyl-intermediate Structures of the Extended-spectrum Class A beta -Lactamase, Toho-1, in Complex with Cefotaxime, Cephalothin, and Benzylpenicillin.
J.Biol.Chem., 277, 2002
1IYP
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TOHO-1 BETA-LACTAMASE IN COMPLEX WITH CEPHALOTHIN
分子名称:Toho-1 beta-lactamase, SULFATE ION, CEPHALOTHIN GROUP
著者Shimamura, T., Ibuka, A., Fushinobu, S., Wakagi, T., Ishiguro, M., Ishii, Y., Matsuzawa, H.
登録日2002-09-04
公開日2002-12-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Acyl-intermediate Structures of the Extended-spectrum Class A beta -Lactamase, Toho-1, in Complex with Cefotaxime, Cephalothin, and Benzylpenicillin.
J.Biol.Chem., 277, 2002
1IYQ
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TOHO-1 BETA-LACTAMASE IN COMPLEX WITH BENZYLPENICILLIN
分子名称:Toho-1 beta-lactamase, SULFATE ION, OPEN FORM - PENICILLIN G
著者Shimamura, T., Ibuka, A., Fushinobu, S., Wakagi, T., Ishiguro, M., Ishii, Y., Matsuzawa, H.
登録日2002-09-04
公開日2002-12-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Acyl-intermediate Structures of the Extended-spectrum Class A beta -Lactamase, Toho-1, in Complex with Cefotaxime, Cephalothin, and Benzylpenicillin.
J.Biol.Chem., 277, 2002
2ZQ7
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APO STRUCTURE OF CLASS A BETA-LACTAMASE TOHO-1 E166A/R274N/R276N TRIPLE MUTANT
分子名称:Beta-lactamase Toho-1, SULFATE ION
著者Shimamura, T., Nitanai, Y., Uchiyama, T., Ago, H., Matsuzawa, H., Miyano, M.
登録日2008-08-07
公開日2009-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (0.94 Å)
主引用文献Improvement of the Crystal Quality by the Surface Mutations on a Beta-Lactamase Toho-1
To be Published
2ZQ8
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APO STRUCTURE OF CLASS A BETA-LACTAMASE TOHO-1 R274N/R276N DOUBLE MUTANT
分子名称:Beta-lactamase Toho-1, SULFATE ION
著者Shimamura, T., Nitanai, Y., Uchiyama, T., Ago, H., Matsuzawa, H., Miyano, M.
登録日2008-08-07
公開日2009-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.03 Å)
主引用文献Improvement of crystal quality by surface mutations of beta-lactamase Toho-1
Acta Crystallogr.,Sect.F, 65, 2009
3RZE
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STRUCTURE OF THE HUMAN HISTAMINE H1 RECEPTOR IN COMPLEX WITH DOXEPIN
分子名称:Histamine H1 receptor, Lysozyme chimera, (3E)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, ...
著者Shimamura, T., Han, G.W., Shiroishi, M., Weyand, S., Tsujimoto, H., Winter, G., Katritch, V., Abagyan, R., Cherezov, V., Liu, W., Kobayashi, T., Stevens, R., Iwata, S., GPCR Network (GPCR)
登録日2011-05-11
公開日2011-06-15
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the human histamine H1 receptor complex with doxepin.
Nature, 475, 2011
2X79
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INWARD FACING CONFORMATION OF MHP1
分子名称:HYDANTOIN TRANSPORT PROTEIN
著者Shimamura, T., Weyand, S., Beckstein, O., Rutherford, N.G., Hadden, J.M., Sharples, D., Sansom, M.S.P., Iwata, S., Henderson, P.J.F., Cameron, A.D.
登録日2010-02-25
公開日2010-05-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1.
Science, 328, 2010
4V4O
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CRYSTAL STRUCTURE OF THE CHAPERONIN COMPLEX CPN60/CPN10/(ADP)7 FROM THERMUS THERMOPHILUS
分子名称:cpn60(GroEL), cpn10(GroES), MAGNESIUM ION, ...
著者Shimamura, T., Koike-Takeshita, A., Yokoyama, K., Masui, R., Murai, N., Yoshida, M., Taguchi, H., Iwata, S.
登録日2004-05-23
公開日2014-07-09
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the native chaperonin complex from Thermus thermophilus revealed unexpected asymmetry at the cis-cavity
STRUCTURE, 12, 2004
2ZIY
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CRYSTAL STRUCTURE OF SQUID RHODOPSIN
分子名称:Rhodopsin, RETINAL, PALMITIC ACID
著者Miyano, M., Shimamura, T.
登録日2008-02-27
公開日2008-05-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Crystal structure of squid rhodopsin with intracellularly extended cytoplasmic region
J.Biol.Chem., 283, 2008
3VG9
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CRYSTAL STRUCTURE OF HUMAN ADENOSINE A2A RECEPTOR WITH AN ALLOSTERIC INVERSE-AGONIST ANTIBODY AT 2.7 A RESOLUTION
分子名称:Adenosine receptor A2a, antibody fab fragment light chain, antibody fab fragment heavy chain, ...
著者Hino, T., Arakawa, T., Iwanari, H., Yurugi-Kobayashi, T., Ikeda-Suno, C., Nakada-Nakura, Y., Kusano-Arai, O., Weyand, S., Shimamura, T., Nomura, N., Cameron, A.D., Kobayashi, T., Hamakubo, T., Iwata, S., Murata, T.
登録日2011-08-04
公開日2012-02-01
最終更新日2012-02-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
Nature, 482, 2012
3VGA
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CRYSTAL STRUCTURE OF HUMAN ADENOSINE A2A RECEPTOR WITH AN ALLOSTERIC INVERSE-AGONIST ANTIBODY AT 3.1 A RESOLUTION
分子名称:Adenosine receptor A2a, antibody fab fragment light chain, antibody fab fragment heavy chain, ...
著者Hino, T., Arakawa, T., Iwanari, H., Yurugi-Kobayashi, T., Ikeda-Suno, C., Nakada-Nakura, Y., Kusano-Arai, O., Weyand, S., Shimamura, T., Nomura, N., Cameron, A.D., Kobayashi, T., Hamakubo, T., Iwata, S., Murata, T.
登録日2011-08-04
公開日2012-02-01
最終更新日2012-02-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
Nature, 482, 2012
5WS3
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CRYSTAL STRUCTURES OF HUMAN OREXIN 2 RECEPTOR BOUND TO THE SELECTIVE ANTAGONIST EMPA DETERMINED BY SERIAL FEMTOSECOND CRYSTALLOGRAPHY AT SACLA
分子名称:Orexin receptor type 2,GlgA glycogen synthase,Orexin receptor type 2, N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide, OLEIC ACID, ...
著者Suno, R., Kimura, K., Nakane, T., Yamashita, K., Wang, J., Fujiwara, T., Yamanaka, Y., Im, D., Tsujimoto, H., Sasanuma, M., Horita, S., Hirokawa, T., Nango, E., Tono, K., Kameshima, T., Hatsui, T., Joti, Y., Yabashi, M., Shimamoto, K., Yamamoto, M., Rosenbaum, D.M., Iwata, S., Shimamura, T., Kobayashi, T.
登録日2016-12-05
公開日2017-12-13
最終更新日2018-06-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA.
Structure, 26, 2018
4X8Y
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CRYSTAL STRUCTURE OF HUMAN PGRMC1 CYTOCHROME B5-LIKE DOMAIN
分子名称:Membrane-associated progesterone receptor component 1, PROTOPORPHYRIN IX CONTAINING FE
著者Nakane, T., Yamamoto, T., Shimamura, T., Kobayashi, T., Kabe, Y., Suematsu, M.
登録日2014-12-11
公開日2016-03-23
最終更新日2016-03-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance
Nat Commun, 7, 2016
5WQC
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CRYSTAL STRUCTURE OF HUMAN OREXIN 2 RECEPTOR BOUND TO THE SELECTIVE ANTAGONIST EMPA DETERMINED BY THE SYNCHROTRON LIGHT SOURCE AT SPRING-8.
分子名称:Orexin receptor type 2,GlgA glycogen synthase,Orexin receptor type 2, N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide, OLEIC ACID, ...
著者Suno, R., Hirata, K., Yamashita, K., Tsujimoto, H., Sasanuma, M., Horita, S., Yamamoto, M., Rosenbaum, D.M., Iwata, S., Shimamura, T., Kobayashi, T.
登録日2016-11-25
公開日2017-11-29
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA
Structure, 26, 2018
2DCH
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CRYSTAL STRUCTURE OF ARCHAEAL INTRON-ENCODED HOMING ENDONUCLEASE I-TSP061I
分子名称:putative homing endonuclease, CHLORIDE ION, SULFATE ION
著者Nakayama, H., Tsuge, H., Shimamura, T., Miyano, M., Nomura, N., Sako, Y.
登録日2006-01-06
公開日2006-07-06
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Structure of a hyperthermophilic archaeal homing endonuclease, I-Tsp061I: contribution of cross-domain polar networks to thermostability.
J.Mol.Biol., 365, 2007
4YBQ
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RAT GLUT5 WITH FV IN THE OUTWARD-OPEN FORM
分子名称:Solute carrier family 2, facilitated glucose transporter member 5, antibody Fv fragment light chain, ...
著者Nomura, N., Shimamura, T., Iwata, S.
登録日2015-02-19
公開日2015-10-07
最終更新日2015-10-28
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献Structure and mechanism of the mammalian fructose transporter GLUT5
Nature, 526, 2015
5XJM
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COMPLEX STRUCTURE OF ANGIOTENSIN II TYPE 2 RECEPTOR WITH FAB
分子名称:Type-2 angiotensin II receptor,Soluble cytochrome b562,Type-2 angiotensin II receptor, FabH, FabL, ...
著者Asada, H., Horita, S., Shimamura, T., Iwata, S.
登録日2017-05-02
公開日2018-07-11
最終更新日2018-07-25
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog
Nat. Struct. Mol. Biol., 25, 2018
2VPW
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POLYSULFIDE REDUCTASE WITH BOUND MENAQUINONE
分子名称:THIOSULFATE REDUCTASE, NRFC PROTEIN, HYPOTHETICAL MEMBRANE SPANNING PROTEIN, ...
著者Jormakka, M., Yokoyama, K., Yano, T., Tamakoshi, M., Akimoto, S., Shimamura, T., Curmi, P., Iwata, S.
登録日2008-03-09
公開日2008-06-10
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Molecular Mechanism of Energy Conservation in Polysulfide Respiration.
Nat.Struct.Mol.Biol., 15, 2008
2VPX
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POLYSULFIDE REDUCTASE WITH BOUND QUINONE (UQ1)
分子名称:THIOSULFATE REDUCTASE, NRFC PROTEIN, HYPOTHETICAL MEMBRANE SPANNING PROTEIN, ...
著者Jormakka, M., Yokoyama, K., Yano, T., Tamakoshi, M., Akimoto, S., Shimamura, T., Curmi, P., Iwata, S.
登録日2008-03-09
公開日2008-06-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Molecular Mechanism of Energy Conservation in Polysulfide Respiration.
Nat.Struct.Mol.Biol., 15, 2008
2VPY
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POLYSULFIDE REDUCTASE WITH BOUND QUINONE INHIBITOR, PENTACHLOROPHENOL (PCP)
分子名称:THIOSULFATE REDUCTASE, NRFC PROTEIN, HYPOTHETICAL MEMBRANE SPANNING PROTEIN, ...
著者Jormakka, M., Yokoyama, K., Yano, T., Tamakoshi, M., Akimoto, S., Shimamura, T., Curmi, P., Iwata, S.
登録日2008-03-09
公開日2008-06-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular Mechanism of Energy Conservation in Polysulfide Respiration.
Nat.Struct.Mol.Biol., 15, 2008
2VPZ
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POLYSULFIDE REDUCTASE NATIVE STRUCTURE
分子名称:THIOSULFATE REDUCTASE, NRFC PROTEIN, HYPOTHETICAL MEMBRANE SPANNING PROTEIN, ...
著者Jormakka, M., Yokoyama, K., Yano, T., Tamakoshi, M., Akimoto, S., Shimamura, T., Curmi, P., Iwata, S.
登録日2008-03-09
公開日2008-06-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular Mechanism of Energy Conservation in Polysulfide Respiration
Nat.Struct.Mol.Biol., 15, 2008
2ZQ9
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CEPHALOTHIN ACYL-INTERMEDIATE STRUCTURE OF CLASS A BETA-LACTAMASE TOHO-1 E166A/R274N/R276N TRIPLE MUTANT
分子名称:Beta-lactamase Toho-1, SULFATE ION, 5-METHYLENE-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, ...
著者Nitanai, Y., Shimamura, T., Uchiyama, T., Ishii, Y., Takehira, M., Yutani, K., Matsuzawa, H., Miyano, M.
登録日2008-08-07
公開日2009-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates
To be Published
2ZQA
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CEFOTAXIME ACYL-INTERMEDIATE STRUCTURE OF CLASS A BETA-LACTA TOHO-1 E166A/R274N/R276N TRIPLE MUTANT
分子名称:Beta-lactamase Toho-1, CEFOTAXIME, C3' cleaved, ...
著者Nitanai, Y., Shimamura, T., Uchiyama, T., Ishii, Y., Takehira, M., Yutani, K., Matsuzawa, H., Miyano, M.
登録日2008-08-07
公開日2009-07-28
最終更新日2018-09-19
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates
To be Published
2ZQC
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AZTREONAM ACYL-INTERMEDIATE STRUCTURE OF CLASS A BETA-LACTAM TOHO-1 E166A/R274N/R276N TRIPLE MUTANT
分子名称:Beta-lactamase Toho-1, SULFATE ION, 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S,3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid
著者Nitanai, Y., Shimamura, T., Uchiyama, T., Ishii, Y., Takehira, M., Yutani, K., Matsuzawa, H., Miyano, M.
登録日2008-08-07
公開日2009-07-28
最終更新日2011-08-31
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates
To be Published
2ZQD
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CEFTAZIDIME ACYL-INTERMEDIATE STRUCTURE OF CLASS A BETA-LACT TOHO-1 E166A/R274N/R276N TRIPLE MUTANT
分子名称:Beta-lactamase Toho-1, SULFATE ION, ACYLATED CEFTAZIDIME
著者Nitanai, Y., Shimamura, T., Uchiyama, T., Ishii, Y., Takehira, M., Yutani, K., Matsuzawa, H., Miyano, M.
登録日2008-08-07
公開日2009-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates
To be Published
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