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2GAR
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A PH-DEPENDENT STABLIZATION OF AN ACTIVE SITE LOOP OBSERVED FROM LOW AND HIGH PH CRYSTAL STRUCTURES OF MUTANT MONOMERIC GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE
分子名称:GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE, PHOSPHATE ION
著者Su, Y., Yamashita, M.M., Greasley, S.E., Mullen, C.A., Shim, J.H., Jennings, P.A., Benkovic, S.J., Wilson, I.A.
登録日1998-05-13
公開日1998-08-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A pH-dependent stabilization of an active site loop observed from low and high pH crystal structures of mutant monomeric glycinamide ribonucleotide transformylase at 1.8 to 1.9 A.
J.Mol.Biol., 281, 1998
3GAR
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A PH-DEPENDENT STABLIZATION OF AN ACTIVE SITE LOOP OBSERVED FROM LOW AND HIGH PH CRYSTAL STRUCTURES OF MUTANT MONOMERIC GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE
分子名称:GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE, PHOSPHATE ION
著者Su, Y., Yamashita, M.M., Greasley, S.E., Mullen, C.A., Shim, J.H., Jennings, P.A., Benkovic, S.J., Wilson, I.A.
登録日1998-05-13
公開日1998-08-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A pH-dependent stabilization of an active site loop observed from low and high pH crystal structures of mutant monomeric glycinamide ribonucleotide transformylase at 1.8 to 1.9 A.
J.Mol.Biol., 281, 1998
1TP7
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CRYSTAL STRUCTURE OF THE RNA-DEPENDENT RNA POLYMERASE FROM HUMAN RHINOVIRUS 16
分子名称:Genome polyprotein, SULFATE ION, 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE
著者Appleby, T.C., Luecke, H., Shim, J.H., Wu, J.Z., Cheney, I.W., Zhong, W., Vogeley, L., Hong, Z., Yao, N.
登録日2004-06-15
公開日2005-06-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of complete rhinovirus RNA polymerase suggests front loading of protein primer.
J.Virol., 79, 2005
3OOB
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STRUCTURAL AND FUNCTIONAL INSIGHTS OF DIRECTLY TARGETING PIN1 BY EPIGALLOCATECHIN-3-GALLATE
分子名称:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ...
著者Urusova, D.V., Shim, J.-H., Kim, D.-J., Jung, S.K., Zykova, T.A., Bode, A.M., Dong, Z.
登録日2010-08-30
公開日2011-08-17
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Epigallocatechin-gallate suppresses tumorigenesis by directly targeting Pin1.
Cancer Prev Res (Phila), 4, 2011
2IJN
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ISOTHIAZOLES AS ACTIVE-SITE INHIBITORS OF HCV NS5B POLYMERASE
分子名称:RNA polymerase NS5B, (2R,3R)-3-{[3,5-BIS(TRIFLUOROMETHYL)PHENYL]AMINO}-2-CYANO-3-THIOXOPROPANAMIDE
著者Yan, S., Yao, N.
登録日2006-09-29
公開日2006-11-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Isothiazoles as active-site inhibitors of HCV NS5B polymerase
Bioorg.Med.Chem.Lett., 17, 2007
3G51
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STRUCTURAL DIVERSITY OF THE ACTIVE CONFORMATION OF THE N-TERMINAL KINASE DOMAIN OF P90 RIBOSOMAL S6 KINASE 2
分子名称:Ribosomal protein S6 kinase alpha-3, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Kurinov, I.
登録日2009-02-04
公開日2009-12-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural diversity of the active N-terminal kinase domain of p90 ribosomal S6 kinase 2
Plos One, 4, 2009
1C2T
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NEW INSIGHTS INTO INHIBITOR DESIGN FROM THE CRYSTAL STRUCTURE AND NMR STUDIES OF E. COLI GAR TRANSFORMYLASE IN COMPLEX WITH BETA-GAR AND 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID.
分子名称:GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE, 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID, GLYCINAMIDE RIBONUCLEOTIDE
著者Greasley, S.E., Yamashita, M.M., Cai, H., Benkovic, S.J., Boger, D.L., Wilson, I.A.
登録日1999-07-26
公開日2000-01-05
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献New insights into inhibitor design from the crystal structure and NMR studies of Escherichia coli GAR transformylase in complex with beta-GAR and 10-formyl-5,8,10-trideazafolic acid.
Biochemistry, 38, 1999
1C3E
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NEW INSIGHTS INTO INHIBITOR DESIGN FROM THE CRYSTAL STRUCTURE AND NMR STUDIES OF E. COLI GAR TRANSFORMYLATE IN COMPLEX WITH BETA-GAR AND 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID.
分子名称:GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE, 2-{4-[2-(2-AMINO-4-HYDROXY-QUINAZOLIN-6-YL)-1-CARBOXY-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, GLYCINAMIDE RIBONUCLEOTIDE
著者Greasley, S.E., Yamashita, M.M., Cai, H., Benkovic, S.J., Boger, D.L., Wilson, I.A.
登録日1999-07-27
公開日1999-12-29
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献New insights into inhibitor design from the crystal structure and NMR studies of Escherichia coli GAR transformylase in complex with beta-GAR and 10-formyl-5,8,10-trideazafolic acid.
Biochemistry, 38, 1999