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6OQA
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BU of 6oqa by Molmil
Crystal structure of CEP250 bound to FKBP12 in the presence of FK506-like novel natural product
Descriptor: (3R,4E,7E,10R,11S,12R,13S,16R,17R,24aS)-11,17-dihydroxy-10,12,16-trimethyl-3-[(2R)-1-phenylbutan-2-yl]-6,9,10,11,12,13,14,15,16,17,22,23,24,24a-tetradecahydro-3H-13,17-epoxypyrido[2,1-c][1,4]oxazacyclohenicosine-1,18,19(21H)-trione, 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ...
Authors:Lee, S.-J, Shigdel, U.K, Townson, S.A, Verdine, G.L.
Deposit date:2019-04-26
Release date:2020-04-29
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W13
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BU of 6w13 by Molmil
Human 8-oxoguanine glycosylase interrogating fully intrahelical oxoG lesion DNA
Descriptor: 2-(2-ethoxyethoxy)ethanethiol, ACETATE ION, DNA (5'-D(P*AP*CP*CP*TP*GP*G)-3'), ...
Authors:Shigdel, U, Verdine, G.
Deposit date:2020-03-03
Release date:2020-09-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase.
Nat Commun, 11, 2020
6W0M
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BU of 6w0m by Molmil
Human 8-oxoguanine glycosylase crosslinked with oxoG lesion containing DNA
Descriptor: 2-(2-ethoxyethoxy)ethanethiol, DNA (5'-D(P*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3'), ...
Authors:Shigdel, U, Verdine, G.
Deposit date:2020-03-02
Release date:2020-09-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase.
Nat Commun, 11, 2020
6W0R
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BU of 6w0r by Molmil
Human 8-oxoguanine glycosylase interrogating fully intrahelical undamaged DNA
Descriptor: 2-(2-ethoxyethoxy)ethanethiol, DNA (5'-D(P*CP*AP*GP*GP*TP*C)-3'), DNA (5'-D(P*CP*CP*TP*GP*G)-3'), ...
Authors:Shigdel, U, Verdine, G.
Deposit date:2020-03-02
Release date:2020-09-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase.
Nat Commun, 11, 2020

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