Author results

6K3I
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SALMONELLA HOOK IN CURVED STATE - 66 SUBUNIT MODELS
Descriptor:Flagellar hook protein FlgE
Authors:Shibata, S., Matsunami, H., Wolf, M., Aizawa, S.
Deposit date:2019-05-19
Release date:2019-10-02
Last modified:2019-11-27
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Torque transmission mechanism of the curved bacterial flagellar hook revealed by cryo-EM.
Nat.Struct.Mol.Biol., 26, 2019
5Z1L
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CRYO-EM STRUCTURE OF METHANOCCUS MARIPALUDIS ARCHAELLUM
Descriptor:Flagellin
Authors:Meshcheryakov, V.A., Shibata, S., Schreiber, M.T., Villar-Briones, A., Jarrell, K.F., Aizawa, S., Wolf, M.
Deposit date:2017-12-26
Release date:2019-02-13
Last modified:2019-05-15
Method:ELECTRON MICROSCOPY (4 Å)
Cite:High-resolution archaellum structure reveals a conserved metal-binding site.
Embo Rep., 20, 2019
3A6P
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CRYSTAL STRUCTURE OF EXPORTIN-5:RANGTP:PRE-MIRNA COMPLEX
Descriptor:Exportin-5, 13-mer peptide, GTP-binding nuclear protein Ran, ...
Authors:Okada, C., Yamashita, E., Lee, S.J., Shibata, S., Katahira, J., Nakagawa, A., Yoneda, Y., Tsukihara, T.
Deposit date:2009-09-07
Release date:2009-12-08
Last modified:2012-04-25
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:A high-resolution structure of the pre-microRNA nuclear export machinery
Science, 326, 2009
4EG1
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH SUBSTRATE METHIONINE
Descriptor:Methionyl-tRNA synthetase, putative, GLYCEROL, ...
Authors:Koh, C.Y., Kim, J.E., Shibata, S., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2012-03-30
Release date:2012-09-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Structure, 20, 2012
4EG3
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH PRODUCT METHIONYL-ADENYLATE
Descriptor:Methionyl-tRNA synthetase, putative, GLYCEROL, ...
Authors:Koh, C.Y., Kim, J.E., Shibata, S., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2012-03-30
Release date:2012-09-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Structure, 20, 2012
4EG4
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR CHEM 1289
Descriptor:Methionyl-tRNA synthetase, putative, GLYCEROL, ...
Authors:Koh, C.Y., Kim, J.E., Shibata, S., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2012-03-30
Release date:2012-09-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.151 Å)
Cite:Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Structure, 20, 2012
4EG5
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR CHEM 1312
Descriptor:Methionyl-tRNA synthetase, putative, GLYCEROL, ...
Authors:Koh, C.Y., Kim, J.E., Shibata, S., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2012-03-30
Release date:2012-09-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Structure, 20, 2012
4EG6
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR CHEM 1325
Descriptor:Methionyl-tRNA synthetase, putative, GLYCEROL, ...
Authors:Koh, C.Y., Kim, J.E., Shibata, S., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2012-03-30
Release date:2012-09-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Structure, 20, 2012
4EG7
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR CHEM 1331
Descriptor:Methionyl-tRNA synthetase, putative, GLYCEROL, ...
Authors:Koh, C.Y., Kim, J.E., Shibata, S., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2012-03-30
Release date:2012-09-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.747 Å)
Cite:Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Structure, 20, 2012
4EG8
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH COMPOUND CHEM 89
Descriptor:Methionyl-tRNA synthetase, putative, GLYCEROL, ...
Authors:Koh, C.Y., Kim, J.E., Shibata, S., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2012-03-30
Release date:2012-09-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.596 Å)
Cite:Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Structure, 20, 2012
4EGA
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR CHEM 1320
Descriptor:Methionyl-tRNA synthetase, putative, GLYCEROL, ...
Authors:Koh, C.Y., Kim, J.E., Shibata, S., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2012-03-30
Release date:2012-09-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.698 Å)
Cite:Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Structure, 20, 2012
4MVW
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR 1-{3-[(3,5-DICHLOROBENZYL)AMINO]PROPYL}-3-THIOPHEN-3-YLUREA (CHEM 1433)
Descriptor:Methionyl-tRNA synthetase, GLYCEROL, DIMETHYL SULFOXIDE, ...
Authors:Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2013-09-24
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Plos Negl Trop Dis, 8, 2014
4MVX
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR 1-{3-[(3,5-DICHLOROBENZYL)AMINO]PROPYL}-3-PHENYLUREA (CHEM 1356)
Descriptor:Methionyl-tRNA synthetase, GLYCEROL, DIMETHYL SULFOXIDE, ...
Authors:Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2013-09-24
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Plos Negl Trop Dis, 8, 2014
4MVY
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR 1-{3-[(3,5-DICHLOROBENZYL)AMINO]PROPYL}-3-(3-HYDROXYPHENYL)UREA (CHEM 1387)
Descriptor:Methionyl-tRNA synthetase, GLYCEROL, DIMETHYL SULFOXIDE, ...
Authors:Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2013-09-24
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.314 Å)
Cite:Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Plos Negl Trop Dis, 8, 2014
4MW0
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR 1-{3-[(3,5-DICHLOROBENZYL)AMINO]PROPYL}-3-(2-HYDROXYPHENYL)UREA (CHEM 1392)
Descriptor:Methionyl-tRNA synthetase, GLYCEROL, DIMETHYL SULFOXIDE, ...
Authors:Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2013-09-24
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Plos Negl Trop Dis, 8, 2014
4MW1
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR 1-{3-[(3-CHLORO-5-METHOXYBENZYL)AMINO]PROPYL}-3-THIOPHEN-3-YLUREA (CHEM 1444)
Descriptor:Methionyl-tRNA synthetase, GLYCEROL, DIMETHYL SULFOXIDE, ...
Authors:Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2013-09-24
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.494 Å)
Cite:Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Plos Negl Trop Dis, 8, 2014
4MW2
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR 1-(3-{[5-CHLORO-2-HYDROXY-3-(PROP-2-EN-1-YL)BENZYL]AMINO}PROPYL)-3-THIOPHEN-3-YLUREA (CHEM 1472)
Descriptor:Methionyl-tRNA synthetase, GLYCEROL, DIMETHYL SULFOXIDE, ...
Authors:Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2013-09-24
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Plos Negl Trop Dis, 8, 2014
4MW4
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR 1-{3-[(5-CHLORO-2-HYDROXY-3-IODOBENZYL)AMINO]PROPYL}-3-THIOPHEN-3-YLUREA (CHEM 1473)
Descriptor:Methionyl-tRNA synthetase, GLYCEROL, DIMETHYL SULFOXIDE, ...
Authors:Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2013-09-24
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Plos Negl Trop Dis, 8, 2014
4MW5
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR 1-{3-[(3-CHLORO-5-METHOXYBENZYL)AMINO]PROPYL}-3-PHENYLUREA (CHEM 1415)
Descriptor:Methionyl-tRNA synthetase, GLYCEROL, DIMETHYL SULFOXIDE, ...
Authors:Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2013-09-24
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.347 Å)
Cite:Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Plos Negl Trop Dis, 8, 2014
4MW6
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR 1-(3-{[2-(BENZYLOXY)-5-CHLORO-3-(PROP-2-EN-1-YL)BENZYL]AMINO}PROPYL)-3-THIOPHEN-3-YLUREA (CHEM 1476)
Descriptor:Methionyl-tRNA synthetase, GLYCEROL, DIMETHYL SULFOXIDE, ...
Authors:Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2013-09-24
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.558 Å)
Cite:Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Plos Negl Trop Dis, 8, 2014
4MW7
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR 1-{3-[(5-CHLORO-2-ETHOXY-3-IODOBENZYL)AMINO]PROPYL}-3-THIOPHEN-3-YLUREA (CHEM 1469)
Descriptor:Methionyl-tRNA synthetase, GLYCEROL, DIMETHYL SULFOXIDE, ...
Authors:Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2013-09-24
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Plos Negl Trop Dis, 8, 2014
4MW9
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR 1-{3-[(3-ETHYNYLBENZYL)AMINO]PROPYL}-3-THIOPHEN-3-YLUREA (CHEM 1478)
Descriptor:Methionyl-tRNA synthetase, GLYCEROL, DIMETHYL SULFOXIDE, ...
Authors:Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2013-09-24
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Plos Negl Trop Dis, 8, 2014
4MWB
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR 1-(3-{[(2,5-DICHLOROTHIOPHEN-3-YL)METHYL]AMINO}PROPYL)-3-THIOPHEN-3-YLUREA (CHEM 1509)
Descriptor:Methionyl-tRNA synthetase, GLYCEROL, DIMETHYL SULFOXIDE, ...
Authors:Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2013-09-24
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.313 Å)
Cite:Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Plos Negl Trop Dis, 8, 2014
4MWC
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR 1-(3-{[(2-METHYL-1-BENZOTHIOPHEN-3-YL)METHYL]AMINO}PROPYL)-3-THIOPHEN-3-YLUREA (CHEM 1540)
Descriptor:Methionyl-tRNA synthetase, GLYCEROL, DIMETHYL SULFOXIDE, ...
Authors:Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2013-09-24
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.649 Å)
Cite:Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Plos Negl Trop Dis, 8, 2014
4MWD
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TRYPANOSOMA BRUCEI METHIONYL-TRNA SYNTHETASE IN COMPLEX WITH INHIBITOR 1-{3-[(3,5-DICHLOROBENZYL)AMINO]PROPYL}-3-THIOPHEN-3-YLUREA (CHEM 1433) AND ATP ANALOG AMPPCP
Descriptor:Methionyl-tRNA synthetase, GLYCEROL, DIMETHYL SULFOXIDE, ...
Authors:Koh, C.Y., Kim, J.E., Wetzel, A.B., de van der Schueren, W.J., Shibata, S., Liu, J., Zhang, Z., Fan, E., Verlinde, C.L.M.J., Hol, W.G.J.
Deposit date:2013-09-24
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.253 Å)
Cite:Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Plos Negl Trop Dis, 8, 2014
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