Author results

1JSW
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NATIVE L-ASPARTATE AMMONIA LYASE
分子名称:L-ASPARTATE AMMONIA-LYASE, BETA-D-GLUCOSE, ACETATE ION
著者Shi, W., Dunbar, J., Farber, G.K.
登録日1997-02-19
公開日1997-06-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structure of L-aspartate ammonia-lyase from Escherichia coli.
Biochemistry, 36, 1997
4P96
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FADR, FATTY ACID RESPONSIVE TRANSCRIPTION FACTOR FROM VIBRIO CHOLERAE
分子名称:Fatty acid metabolism regulator protein
著者Shi, W., Kull, F.J.
登録日2014-04-02
公開日2015-02-04
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The 40-residue insertion in Vibrio cholerae FadR facilitates binding of an additional fatty acyl-CoA ligand.
Nat Commun, 6, 2015
4PDK
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FADR, FATTY ACID RESPONSIVE TRANSCRIPTION FACTOR FROM VIBRIO CHOLERAE, IN COMPLEX WITH OLEOYL-COA
分子名称:Fatty acid metabolism regulator protein, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name)
著者Shi, W., Kull, F.J.
登録日2014-04-19
公開日2015-02-18
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The 40-residue insertion in Vibrio cholerae FadR facilitates binding of an additional fatty acyl-CoA ligand.
Nat Commun, 6, 2015
1BZY
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HUMAN HGPRTASE WITH TRANSITION STATE INHIBITOR
分子名称:HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, MAGNESIUM ION, PHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN-2-YLMETHYL] ESTER, ...
著者Shi, W., Li, C., Tyler, P.C., Furneaux, R.H., Grubmeyer, C., Schramm, V.L., Almo, S.C.
登録日1998-11-05
公開日1999-06-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor.
Nat.Struct.Biol., 6, 1999
1CI0
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PNP OXIDASE FROM SACCHAROMYCES CEREVISIAE
分子名称:PROTEIN (PNP OXIDASE), FLAVIN MONONUCLEOTIDE
著者Shi, W., Ostrov, D.A., Gerchman, S.E., Graziano, V., Kycia, H., Studier, B., Almo, S.C., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日1999-04-06
公開日1999-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Structure of PNP Oxidase from S. Cerevisiae
To be Published
1CJB
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MALARIAL PURINE PHOSPHORIBOSYLTRANSFERASE
分子名称:PROTEIN (HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE), MAGNESIUM ION, (1S)-1(9-DEAZAHYPOXANTHIN-9YL)1,4-DIDEOXY-1,4-IMINO-D-RIBITOL-5-PHOSPHATE, ...
著者Shi, W., Li, C.M., Tyler, P.C., Furneaux, R.H., Cahill, S.M., Girvin, M.E., Grubmeyer, C., Schramm, V.L., Almo, S.C.
登録日1999-04-08
公開日1999-08-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor.
Biochemistry, 38, 1999
1DQN
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CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH A TRANSITION STATE ANALOGUE
分子名称:GUANINE PHOSPHORIBOSYLTRANSFERASE, MAGNESIUM ION, PHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN-2-YLMETHYL] ESTER, ...
著者Shi, W., Munagala, N.R., Wang, C.C., Li, C.M., Tyler, P.C., Furneaux, R.H., Grubmeyer, C., Schramm, V.L., Almo, S.C.
登録日2000-01-04
公開日2000-07-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).
Biochemistry, 39, 2000
1DQP
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CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH IMMUCILLING
分子名称:GUANINE PHOSPHORIBOSYLTRANSFERASE, 1,4-DIDEOXY-1,4-IMINO-1-(S)-(9-DEAZAGUANIN-9-YL)-D-RIBITOL, ISOPROPYL ALCOHOL
著者Shi, W., Munagala, N.R., Wang, C.C., Li, C.M., Tyler, P.C., Furneaux, R.H., Grubmeyer, C., Schramm, V.L., Almo, S.C.
登録日2000-01-04
公開日2000-07-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).
Biochemistry, 39, 2000
1EZR
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CRYSTAL STRUCTURE OF NUCLEOSIDE HYDROLASE FROM LEISHMANIA MAJOR
分子名称:NUCLEOSIDE HYDROLASE, CALCIUM ION
著者Shi, W., Schramm, V.L., Almo, S.C.
登録日2000-05-11
公開日2000-05-24
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-a crystal structure.
J.Biol.Chem., 274, 1999
1G2O
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CRYSTAL STRUCTURE OF PURINE NUCLEOSIDE PHOSPHORYLASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH A TRANSITION-STATE INHIBITOR
分子名称:PURINE NUCLEOSIDE PHOSPHORYLASE, PHOSPHATE ION, 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL
著者Shi, W., Basso, L.A., Tyler, P.C., Furneaux, R.H., Blanchard, J.S., Almo, S.C., Schramm, V.L.
登録日2000-10-20
公開日2001-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces.
Biochemistry, 40, 2001
1G2P
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CRYSTAL STRUCTURE OF ADENINE PHOSPHORIBOSYLTRANSFERASE
分子名称:ADENINE PHOSPHORIBOSYLTRANSFERASE 1, SULFATE ION
著者Shi, W., Tanaka, K.S.E., Almo, S.C., Schramm, V.L.
登録日2000-10-20
公開日2001-12-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural analysis of adenine phosphoribosyltransferase from Saccharomyces cerevisiae.
Biochemistry, 40, 2001
1G2Q
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CRYSTAL STRUCTURE OF ADENINE PHOSPHORIBOSYLTRANSFERASE
分子名称:ADENINE PHOSPHORIBOSYLTRANSFERASE 1
著者Shi, W., Tanaka, K.S.E., Almo, S.C., Schramm, V.L.
登録日2000-10-20
公開日2001-12-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural analysis of adenine phosphoribosyltransferase from Saccharomyces cerevisiae.
Biochemistry, 40, 2001
1I80
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CRYSTAL STRUCTURE OF M. TUBERCULOSIS PNP IN COMPLEX WITH IMINORIBITOL, 9-DEAZAHYPOXANTHINE AND PHOSPHATE ION
分子名称:PURINE NUCLEOSIDE PHOSPHORYLASE, PHOSPHATE ION, 9-DEAZAHYPOXANTHINE, ...
著者Shi, W., Basso, L.A., Tyler, P.C., Furneaux, R.H., Blanchard, J.S., Almo, S.C., Schramm, V.L.
登録日2001-03-12
公開日2001-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces.
Biochemistry, 40, 2001
1L1Q
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CRYSTAL STRUCTURE OF APRTASE FROM GIARDIA LAMBLIA COMPLEXED WITH 9-DEAZAADENINE
分子名称:Adenine phosphoribosyltransferase, SULFATE ION, 9-DEAZAADENINE
著者Shi, W., Sarver, A.E., Wang, C.C., Tanaka, K.S., Almo, S.C., Schramm, V.L.
登録日2002-02-19
公開日2002-11-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Closed Site Complexes of Adenine Phosphoribosyltransferase from Giardia lamblia Reveal a Mechanism of Ribosyl Migration.
J.Biol.Chem., 277, 2002
1L1R
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CRYSTAL STRUCTURE OF APRTASE FROM GIARDIA LAMBLIA COMPLEXED WITH 9-DEAZAADENINE, MG2+ AND PRPP
分子名称:Adenine phosphoribosyltransferase, MAGNESIUM ION, 9-DEAZAADENINE, ...
著者Shi, W., Sarver, A.E., Wang, C.C., Tanaka, K.S., Almo, S.C., Schramm, V.L.
登録日2002-02-19
公開日2002-11-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Closed Site Complexes of Adenine Phosphoribosyltransferase from Giardia lamblia Reveal a Mechanism of Ribosyl Migration.
J.Biol.Chem., 277, 2002
1NW4
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM PURINE NUCLEOSIDE PHOSPHORYLASE IN COMPLEX WITH IMMH AND SULFATE
分子名称:uridine phosphorylase, putative, SULFATE ION, ...
著者Shi, W., Ting, L.M., Kicska, G.A., Lewandowicz, A., Tyler, P.C., Evans, G.B., Furneaux, R.H., Kim, K., Almo, S.C., Schramm, V.L.
登録日2003-02-05
公開日2004-03-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Plasmodium falciparum Purine Nucleoside Phosphorylase: CRYSTAL STRUCTURES, IMMUCILLIN INHIBITORS, AND DUAL CATALYTIC FUNCTION.
J.Biol.Chem., 279, 2004
1Q1G
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM PNP WITH 5'-METHYLTHIO-IMMUCILLIN-H
分子名称:Uridine phosphorylase putative, SULFATE ION, 3,4-DIHYDROXY-2-[(METHYLSULFANYL)METHYL]-5-(4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)PYRROLIDINIUM, ...
著者Shi, W., Ting, L.M., Kicska, G.A., Lewandowicz, A., Tyler, P.C., Evans, G.B., Furneaux, R.H., Kim, K., Almo, S.C., Schramm, V.L.
登録日2003-07-19
公開日2004-03-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Plasmodium falciparum Purine Nucleoside Phosphorylase: CRYSTAL STRUCTURES, IMMUCILLIN INHIBITORS, AND DUAL CATALYTIC FUNCTION.
J.Biol.Chem., 279, 2004
1RR6
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STRUCTURE OF HUMAN PURINE NUCLEOSIDE PHOSPHORYLASE IN COMPLEX WITH IMMUCILLIN-H AND PHOSPHATE
分子名称:Purine nucleoside phosphorylase, PHOSPHATE ION, 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL
著者Shi, W., Lewandowicz, A., Tyler, P.C., Furneaux, R.H., Almo, S.C., Schramm, V.L.
登録日2003-12-08
公開日2005-02-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function.
J.Biol.Chem., 279, 2004
1RSZ
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STRUCTURE OF HUMAN PURINE NUCLEOSIDE PHOSPHORYLASE IN COMPLEX WITH DADME-IMMUCILLIN-H AND SULFATE
分子名称:Purine nucleoside phosphorylase, SULFATE ION, 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one
著者Shi, W., Lewandowicz, A., Tyler, P.C., Furneaux, R.H., Almo, S.C., Schramm, V.L.
登録日2003-12-10
公開日2005-02-22
最終更新日2018-12-12
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural comparison of human and malarial purine nucleoside phosphorylases
To be Published
1RT9
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STRUCTURE OF HUMAN PURINE NUCLEOSIDE PHOSPHORYLASE IN COMPLEX WITH IMMUCILLIN-H AND SULFATE
分子名称:Purine nucleoside phosphorylase, SULFATE ION, 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL
著者Shi, W., Lewandowicz, A., Tyler, P.C., Furneaux, R.H., Almo, S.C., Schramm, V.L.
登録日2003-12-10
公開日2005-02-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural comparison of human and malarial purine nucleoside phosphorylases
To be Published
1ZVM
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CRYSTAL STRUCTURE OF HUMAN CD38: CYCLIC-ADP-RIBOSYL SYNTHETASE/NAD+ GLYCOHYDROLASE
分子名称:ADP-ribosyl cyclase 1, SULFATE ION
著者Shi, W., Yang, T., Almo, S.C., Schramm, V.L., Sauve, A.
登録日2005-06-02
公開日2006-06-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of human CD38: Cyclic-ADP-ribosyl synthetase/NAD+ glycohydrolase
To be Published
3K9A
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CRYSTAL STRUCTURE OF HIV GP41 WITH MPER
分子名称:HIV glycoprotein gp41
著者Shi, W., Han, D., Habte, H., Cho, M., Chance, M.R.
登録日2009-10-15
公開日2010-05-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural characterization of HIV gp41 with the membrane-proximal external region
J.Biol.Chem., 285, 2010
4P9U
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FADR, FATTY ACID RESPONSIVE TRANSCRIPTION FACTOR FROM VIBRIO CHOLERAE, IN COMPLEX WITH DNA
分子名称:Fatty acid metabolism regulator protein, DNA (31-MER)
著者Kull, F.J., Shi, W.
登録日2014-04-05
公開日2015-02-04
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (3.208 Å)
主引用文献The 40-residue insertion in Vibrio cholerae FadR facilitates binding of an additional fatty acyl-CoA ligand.
Nat Commun, 6, 2015
1K27
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CRYSTAL STRUCTURE OF 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE IN COMPLEX WITH A TRANSITION STATE ANALOGUE
分子名称:5'-Deoxy-5'-Methylthioadenosine Phosphorylase, PHOSPHATE ION, (3S,4R)-2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-[(METHYLSULFANYL)METHYL]PYRROLIDINE-3,4-DIOL
著者Shi, W., Singh, V., Tyler, P.C., Furneaux, R.H., Almo, S.C., Schramm, V.L.
登録日2001-09-26
公開日2003-09-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A
Biochemistry, 43, 2004
1ZOS
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STRUCTURE OF 5'-METHYLTHIONADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE FROM S. PNEUMONIAE WITH A TRANSITION-STATE INHIBITOR MT-IMMA
分子名称:5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase, (3S,4R)-2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-[(METHYLSULFANYL)METHYL]PYRROLIDINE-3,4-DIOL
著者Shi, W., Singh, V., Zhen, R., Tyler, P.C., Furneaux, R.H., Almo, S.C., Schramm, V.L.
登録日2005-05-13
公開日2006-04-25
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae.
Biochemistry, 45, 2006