Author results

2MUX
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SUMO2 NON-COVALENTLY INTERACTS WITH USP25 AND DOWNREGULATES ITS ACTIVITY
分子名称:Ubiquitin carboxyl-terminal hydrolase 25
著者Shi, L., Zhang, N., Wen, Y.
登録日2014-09-18
公開日2016-04-20
実験手法SOLUTION NMR
主引用文献SUMO2 non-covalently interacts with USP25 and downregulates its activity
To be Published
2PZ0
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CRYSTAL STRUCTURE OF GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE (GDPD) FROM T. TENGCONGENSIS
分子名称:Glycerophosphoryl diester phosphodiesterase, CALCIUM ION, GLYCEROL
著者Shi, L., Liu, J.F., An, X.M., Liang, D.C.
登録日2007-05-17
公開日2008-04-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Crystal structure of glycerophosphodiester phosphodiesterase (GDPD) from Thermoanaerobacter tengcongensis, a metal ion-dependent enzyme: insight into the catalytic mechanism.
Proteins, 72, 2008
6ITW
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CRYSTAL STRUCTURE OF ATU4351 FROM AGROBACTERIUM TUMEFACIENS
分子名称:Type VI immunity protein Atu4351
著者Shi, L., Gao, Z., Zhang, H., Dong, Y.
登録日2018-11-26
公開日2019-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the type VI immunity protein Tdi1 (Atu4351) from Agrobacterium tumefaciens.
Acta Crystallogr F Struct Biol Commun, 75, 2019
3GM5
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CRYSTAL STRUCTURE OF A PUTATIVE METHYLMALONYL-COENZYME A EPIMERASE FROM THERMOANAEROBACTER TENGCONGENSIS AT 2.0 A RESOLUTION
分子名称:Lactoylglutathione lyase and related lyases, CITRIC ACID, SULFATE ION
著者Liang, D.-C., Shi, L., Gao, P., Yan, X.-X.
登録日2009-03-12
公開日2009-09-22
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a putative methylmalonyl-coenzyme a epimerase from Thermoanaerobacter tengcongensis at 2.0 A resolution
Proteins, 77, 2009
2KB7
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HYBRID SOLUTION AND SOLID-STATE NMR STRUCTURE OF MONOMERIC PHOSPHOLAMBAN IN LIPID BILAYERS
分子名称:Phospholamban
著者Traaseth, N.J., Shi, L., Verardi, R., Veglia, G.
登録日2008-11-21
公開日2009-06-16
最終更新日2011-07-13
実験手法SOLUTION NMR, SOLID-STATE NMR
主引用文献Structure and topology of monomeric phospholamban in lipid membranes determined by a hybrid solution and solid-state NMR approach.
Proc.Natl.Acad.Sci.USA, 106, 2009
2LZE
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LIGASE 10C
分子名称:a primordial catalytic fold generated by in vitro evolution, ZINC ION
著者Chao, F., Morelli, A., Haugner, J., Churchfield, L., Hagmann, L., Shi, L., Masterson, L., Sarangi, R., Veglia, G., Seelig, B.
登録日2012-10-01
公開日2012-10-24
最終更新日2013-02-06
実験手法SOLUTION NMR
主引用文献Structure and dynamics of a primordial catalytic fold generated by in vitro evolution.
Nat.Chem.Biol., 9, 2013
1Z68
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CRYSTAL STRUCTURE OF HUMAN FIBROBLAST ACTIVATION PROTEIN ALPHA
分子名称:fibroblast activation protein, alpha subunit, N-ACETYL-D-GLUCOSAMINE, ...
著者Aertgeerts, K., Levin, I., Shi, L., Prasad, G.S., Zhang, Y., Kraus, M.L., Salakian, S., Snell, G.P., Sridhar, V., Wijnands, R., Tennant, M.G.
登録日2005-03-21
公開日2005-04-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha.
J.Biol.Chem., 280, 2005
1ZJ6
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CRYSTAL STRUCTURE OF HUMAN ARL5
分子名称:ADP-ribosylation factor-like protein 5, SULFATE ION, GUANOSINE-3'-MONOPHOSPHATE-5'-DIPHOSPHATE
著者Wang, Z.X., Shi, L., Liu, J.F., An, X.M., Chang, W.R., Liang, D.C.
登録日2005-04-28
公開日2005-06-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献2.0A crystal structure of human ARL5-GDP3'P, a novel member of the small GTP-binding proteins
Biochem.Biophys.Res.Commun., 332, 2005
2KYV
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HYBRID SOLUTION AND SOLID-STATE NMR STRUCTURE ENSEMBLE OF PHOSPHOLAMBAN PENTAMER
分子名称:Phospholamban
著者Verardi, R., Shi, L., Traaseth, N.J., Veglia, G.
登録日2010-06-08
公開日2011-05-11
最終更新日2011-07-13
実験手法SOLUTION NMR, SOLID-STATE NMR
主引用文献Structural topology of phospholamban pentamer in lipid bilayers by a hybrid solution and solid-state NMR method.
Proc.Natl.Acad.Sci.USA, 108, 2011
2LPF
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R STATE STRUCTURE OF MONOMERIC PHOSPHOLAMBAN (C36A, C41F, C46A)
分子名称:Cardiac phospholamban
著者De Simone, A., Montalvao, R.W., Gustavsson, M., Shi, L., Veglia, G., Vendruscolo, M.
登録日2012-02-11
公開日2013-02-13
最終更新日2013-10-09
実験手法SOLUTION NMR
主引用文献Structures of the Excited States of Phospholamban and Shifts in Their Populations upon Phosphorylation.
Biochemistry, 52, 2013
2M3G
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STRUCTURE OF ANABAENA SENSORY RHODOPSIN DETERMINED BY SOLID STATE NMR SPECTROSCOPY
分子名称:Anabaena Sensory Rhodopsin, RETINAL
著者Wang, S., Munro, R.A., Shi, L., Kawamura, I., Okitsu, T., Wada, A., Kim, S., Jung, K., Brown, L.S., Ladizhansky, V.
登録日2013-01-17
公開日2013-08-21
最終更新日2015-06-17
実験手法SOLID-STATE NMR
主引用文献Solid-state NMR spectroscopy structure determination of a lipid-embedded heptahelical membrane protein.
Nat.Methods, 10, 2013
2M89
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SOLUTION STRUCTURE OF THE AHA1 DIMER FROM COLWELLIA PSYCHRERYTHRAEA
分子名称:Aha1 domain protein
著者Rossi, P., Sgourakis, N.G., Shi, L., Liu, G., Barbieri, C.M., Lee, H., Grant, T.D., Luft, J.R., Xiao, R., Acton, T.B., Montelione, G.T., Snell, E.H., Baker, D., Lange, O.A., Northeast Structural Genomics Consortium (NESG)
登録日2013-05-09
公開日2013-09-04
最終更新日2016-04-27
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献A hybrid NMR/SAXS-based approach for discriminating oligomeric protein interfaces using Rosetta.
Proteins, 83, 2015
2MT6
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SOLUTION STRUCTURE OF THE HUMAN UBIQUITIN CONJUGATING ENZYME UBE2W
分子名称:Ubiquitin-conjugating enzyme E2 W
著者Vittal, V., Shi, L., Wenzel, D.M., Brzovic, P.S., Klevit, R.E.
登録日2014-08-14
公開日2014-11-26
最終更新日2015-01-14
実験手法SOLUTION NMR
主引用文献Intrinsic disorder drives N-terminal ubiquitination by Ube2w.
Nat.Chem.Biol., 11, 2015
2MUU
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THE PROTEOLYTIC ACTIVITY OF UBIQUITIN-SPECIFIC PROTEASE 28 IS MODULATED BY THE N-TERMINAL DOMAIN
分子名称:Ubiquitin carboxyl-terminal hydrolase 28
著者Wen, Y., Shi, L., Zhang, N.
登録日2014-09-17
公開日2016-04-20
実験手法SOLUTION NMR
主引用文献The N-terminal ubiquitin-binding region of ubiquitin-specific protease 28 modulates its deubiquitination function: NMR structural and mechanistic insights.
Biochem.J., 471, 2015
2N0K
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CHEMICAL SHIFT ASSIGNMENTS AND STRUCTURE OF THE ALPHA-CRYSTALLIN DOMAIN FROM HUMAN, HSPB5
分子名称:Alpha-crystallin B chain
著者Rajagopal, P., Klevit, R.E., Shi, L., Baker, D.
登録日2015-03-09
公開日2015-06-03
最終更新日2017-02-15
実験手法SOLUTION NMR
主引用文献A conserved histidine modulates HSPB5 structure to trigger chaperone activity in response to stress-related acidosis.
Elife, 4, 2015
2N3J
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SOLUTION STRUCTURE OF THE ALPHA-CRYSTALLIN DOMAIN FROM THE REDOX-SENSITIVE CHAPERONE, HSPB1
分子名称:Heat shock protein beta-1
著者Rajagopal, P., Liu, Y., Shi, L., Klevit, R.E.
登録日2015-06-03
公開日2015-08-19
最終更新日2015-10-14
実験手法SOLUTION NMR
主引用文献Structure of the alpha-crystallin domain from the redox-sensitive chaperone, HSPB1.
J.Biomol.Nmr, 63, 2015
2ONC
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CRYSTAL STRUCTURE OF HUMAN DPP-4
分子名称:Dipeptidyl peptidase 4, N-ACETYL-D-GLUCOSAMINE, 2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE
著者Feng, J., Zhang, Z., Wallace, M.B., Stafford, J.A., Kaldor, S.W., Kassel, D.B., Navre, M., Shi, L., Skene, R.J., Asakawa, T., Takeuchi, K., Xu, R., Webb, D.R., Gwaltney, S.L.
登録日2007-01-23
公開日2008-03-04
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Discovery of alogliptin: a potent, selective, bioavailable, and efficacious inhibitor of dipeptidyl peptidase IV.
J.Med.Chem., 50, 2007
2QDL
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CRYSTAL STRUCTURE OF SCAFFOLDING PROTEIN TTCHEW FROM THERMOANAEROBACTER TENGCONGENSIS
分子名称:Chemotaxis signal transduction protein, GLYCEROL
著者Yao, W., Shi, L., Liang, D.C.
登録日2007-06-21
公開日2007-09-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of scaffolding protein CheW from thermoanaerobacter tengcongensis.
Biochem.Biophys.Res.Commun., 361, 2007
3G0B
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CRYSTAL STRUCTURE OF DIPEPTIDYL PEPTIDASE IV IN COMPLEX WITH TAK-322
分子名称:Dipeptidyl peptidase 4, N-ACETYL-D-GLUCOSAMINE, 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl}methyl)benzonitrile
著者Zhang, Z., Wallace, M.B., Feng, J., Stafford, J.A., Kaldor, S.W., Shi, L., Skene, R.J., Aertgeerts, K., Lee, B., Jennings, A., Xu, R., Kassel, D., Webb, D.R., Gwaltney, S.L.
登録日2009-01-27
公開日2010-02-16
最終更新日2016-04-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Design and Synthesis of Pyrimidinone and Pyrimidinedione Inhibitors of Dipeptidyl Peptidase IV.
J.Med.Chem., 54, 2011
3G0C
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CRYSTAL STRUCTURE OF DIPEPTIDYL PEPTIDASE IV IN COMPLEX WITH A PYRIMIDINEDIONE INHIBITOR 1
分子名称:Dipeptidyl peptidase 4, 7-(2-chlorobenzyl)-1,3-dimethyl-8-piperazin-1-yl-3,7-dihydro-1H-purine-2,6-dione, N-ACETYL-D-GLUCOSAMINE
著者Zhang, Z., Wallace, M.B., Feng, J., Stafford, J.A., Kaldor, S.W., Shi, L., Skene, R.J., Aertgeerts, K., Lee, B., Jennings, A., Xu, R., Kassel, D., Webb, D.R., Gwaltney, S.L.
登録日2009-01-27
公開日2010-02-16
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Design and Synthesis of Pyrimidinone and Pyrimidinedione Inhibitors of Dipeptidyl Peptidase IV.
J.Med.Chem., 54, 2011
3G0D
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CRYSTAL STRUCTURE OF DIPEPTIDYL PEPTIDASE IV IN COMPLEX WITH A PYRIMIDINEDIONE INHIBITOR 2
分子名称:Dipeptidyl peptidase 4, 2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE, N-ACETYL-D-GLUCOSAMINE
著者Zhang, Z., Wallace, M.B., Feng, J., Stafford, J.A., Kaldor, S.W., Shi, L., Skene, R.J., Aertgeerts, K., Lee, B., Jennings, A., Xu, R., Kassel, D., Webb, D.R., Gwaltney, S.L.
登録日2009-01-27
公開日2010-02-16
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Design and Synthesis of Pyrimidinone and Pyrimidinedione Inhibitors of Dipeptidyl Peptidase IV.
J.Med.Chem., 54, 2011
3G0G
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CRYSTAL STRUCTURE OF DIPEPTIDYL PEPTIDASE IV IN COMPLEX WITH A PYRIMIDINONE INHIBITOR 3
分子名称:Dipeptidyl peptidase 4, 2-({2-[(3R)-3-aminopiperidin-1-yl]-5-bromo-6-oxopyrimidin-1(6H)-yl}methyl)benzonitrile, N-ACETYL-D-GLUCOSAMINE
著者Zhang, Z., Wallace, M.B., Feng, J., Stafford, J.A., Kaldor, S.W., Shi, L., Skene, R.J., Aertgeerts, K., Lee, B., Jennings, A., Xu, R., Kassel, D., Webb, D.R., Gwaltney, S.L.
登録日2009-01-27
公開日2010-02-16
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Design and Synthesis of Pyrimidinone and Pyrimidinedione Inhibitors of Dipeptidyl Peptidase IV.
J.Med.Chem., 54, 2011
4HMK
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CRYSTAL STRUCTURE OF LEUT-E290S WITH BOUND BR
分子名称:Transporter, LEUCINE, SODIUM ION, ...
著者Kantcheva, A.K., Quick, M., Shi, L., Winther, A.M.L., Stolzenberg, S., Weinstein, H., Javitch, J.A., Nissen, P.
登録日2012-10-18
公開日2013-05-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The chloride binding site of Neurotransmitter Sodium Symporters
Proc.Natl.Acad.Sci.USA, 2013
4HOD
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CRYSTAL STRUCTURE OF LEUT-E290S WITH BOUND CL
分子名称:Transporter, LEUCINE, SODIUM ION, ...
著者Kantcheva, A.K., Quick, M., Shi, L., Winther, A.M.L., Stolzenberg, S., Weinstein, H., Javitch, J.A., Nissen, P.
登録日2012-10-22
公開日2013-05-08
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The chloride binding site of Neurotransmitter Sodium Symporters
Proc.Natl.Acad.Sci.USA, 2013
6G4J
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STRUCTURE OF THE PROTEIN KINASE YABT FROM BACILLUS SUBTILIS IN COMPLEX WITH AN ALPHAREP CRYSTALLIZATION HELPER
分子名称:Probable serine/threonine-protein kinase YabT, alphaREP bE8
著者Nessler, S., Cavagnino, A., Rabefiraisana, J.L.
登録日2018-03-27
公開日2019-01-30
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Structural Analysis of the Hanks-Type Protein Kinase YabT FromBacillus subtilisProvides New Insights in its DNA-Dependent Activation.
Front Microbiol, 9, 2018
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