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7OQ4
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BU of 7oq4 by Molmil
Cryo-EM structure of the ATV RNAP Inhibitory Protein (RIP) bound to the DNA-binding channel of the host's RNA polymerase
Descriptor: Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ...
Authors:Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F.
Deposit date:2021-06-02
Release date:2021-08-25
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
7OQY
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BU of 7oqy by Molmil
Cryo-EM structure of the cellular negative regulator TFS4 bound to the archaeal RNA polymerase
Descriptor: Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ...
Authors:Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F.
Deposit date:2021-06-04
Release date:2021-08-25
Last modified:2021-11-03
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
7OK0
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BU of 7ok0 by Molmil
Cryo-EM structure of the Sulfolobus acidocaldarius RNA polymerase at 2.88 A
Descriptor: Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ...
Authors:Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F.
Deposit date:2021-05-17
Release date:2021-08-25
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
1R6G
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BU of 1r6g by Molmil
Crystal structure of the thyroid hormone receptor beta ligand binding domain in complex with a beta selective compound
Descriptor: 2-[3,5-DIBROMO-4-(4-HYDROXY-3-{HYDROXY[(2-PHENYLETHYL)AMINO]METHYL}PHENOXY)PHENYL]ETHANE-1,1-DIOL, Thyroid hormone receptor beta-1
Authors:Hangeland, J.J, Dejneka, T, Friends, T.J, Devasthale, P, Mellstrom, K, Sandberg, J, Grynfarb, M, Doweyko, A.M, Sack, J.S, Einspahr, H, Farnegardh, M, Husman, B, Ljunggren, J, Koehler, K, Sheppard, C, Malm, J, Ryono, D.E.
Deposit date:2003-10-15
Release date:2005-02-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Thyroid receptor ligands. Part 2: Thyromimetics with improved selectivity for the thyroid hormone receptor beta.
Bioorg.Med.Chem.Lett., 14, 2004
2MC5
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BU of 2mc5 by Molmil
A bacteriophage transcription regulator inhibits bacterial transcription initiation by -factor displacement
Descriptor: 45L
Authors:Liu, B, Shadrin, A, Sheppard, C, Xu, Y, Severinov, K, Matthews, S, Wigneshweraraj, S.
Deposit date:2013-08-14
Release date:2014-03-26
Last modified:2014-04-30
Method:SOLUTION NMR
Cite:A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor displacement.
Nucleic Acids Res., 42, 2014
2MC6
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BU of 2mc6 by Molmil
A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor displacement
Descriptor: DNA-directed RNA polymerase subunit beta', RNA polymerase inhibitor p7
Authors:Liu, B, Shadrin, A, Sheppard, C, Xu, Y, Severinov, K, Matthews, S, Wigneshweraraj, S.
Deposit date:2013-08-15
Release date:2014-04-02
Last modified:2014-05-07
Method:SOLUTION NMR
Cite:A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor displacement.
Nucleic Acids Res., 42, 2014
5LGM
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BU of 5lgm by Molmil
Gp5.7 mutant L42A
Descriptor: Fusion protein 5.5/5.7
Authors:Liu, B, Matthews, S.
Deposit date:2016-07-07
Release date:2017-08-16
Method:SOLUTION NMR
Cite:Gp5.7 mutant L42A
to be published
2LMC
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BU of 2lmc by Molmil
Structure of T7 transcription factor Gp2-E. coli RNAp jaw domain complex
Descriptor: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit beta
Authors:Liu, M.
Deposit date:2011-11-29
Release date:2012-03-14
Last modified:2012-10-03
Method:SOLUTION NMR
Cite:Structural and Mechanistic Basis for the Inhibition of Escherichia coli RNA Polymerase by T7 Gp2.
Mol.Cell, 47, 2012

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