Author results

1N1A
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN FKBP52
Descriptor:FKBP52
Authors:Li, P., Ding, Y., Wu, B., Shu, C., Shen, B., Rao, Z.
Deposit date:2002-10-16
Release date:2002-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the N-terminal domain of human FKBP52.
Acta Crystallogr.,Sect.D, 59, 2003
1P5Q
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CRYSTAL STRUCTURE OF FKBP52 C-TERMINAL DOMAIN
Descriptor:FK506-binding protein 4, SULFATE ION
Authors:Wu, B., Li, P., Lou, Z., Shu, C., Ding, Y., Shen, B., Rao, Z.
Deposit date:2003-04-28
Release date:2004-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:3D structure of human FK506-binding protein 52: Implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex
Proc.Natl.Acad.Sci.USA, 101, 2004
1Q1C
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CRYSTAL STRUCTURE OF N(1-260) OF HUMAN FKBP52
Descriptor:FK506-binding protein 4, DIMETHYL SULFOXIDE, 1,2-ETHANEDIOL
Authors:Wu, B., Li, P., Lou, Z., Ding, Y., Shu, C., Shen, B., Rao, Z.
Deposit date:2003-07-18
Release date:2004-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:3D structure of human FK506-binding protein 52: Implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex
Proc.Natl.Acad.Sci.USA, 101, 2004
1QZ2
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CRYSTAL STRUCTURE OF FKBP52 C-TERMINAL DOMAIN COMPLEX WITH THE C-TERMINAL PEPTIDE MEEVD OF HSP90
Descriptor:FK506-binding protein 4, 5-mer peptide from Heat shock protein HSP 90
Authors:Wu, B., Li, P., Lou, Z., Liu, Y., Ding, Y., Shu, C., Shen, B., Rao, Z.
Deposit date:2003-09-15
Release date:2004-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:3D structure of human FK506-binding protein 52: Implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex.
Proc.Natl.Acad.Sci.USA, 101, 2004
1RWZ
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CRYSTAL STRUCTURE OF PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) FROM A. FULGIDUS
Descriptor:DNA polymerase sliding clamp
Authors:Chapados, B.R., Hosfield, D.J., Han, S., Qiu, J., Yelent, B., Shen, B., Tainer, J.A.
Deposit date:2003-12-17
Release date:2004-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
Cell(Cambridge,Mass.), 116, 2004
1RXM
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C-TERMINAL REGION OF FEN-1 BOUND TO A. FULGIDUS PCNA
Descriptor:DNA polymerase sliding clamp, consensus FEN-1 peptide
Authors:Chapados, B.R., Hosfield, D.J., Han, S., Qiu, J., Yelent, B., Shen, B., Tainer, J.A.
Deposit date:2003-12-18
Release date:2004-01-27
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
Cell(Cambridge,Mass.), 116, 2004
1RXV
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CRYSTAL STRUCTURE OF A. FULGIDUS FEN-1 BOUND TO DNA
Descriptor:5'-d(*T*pA*pG*pC*pA*pT*pC*pG*pG), Flap structure-specific endonuclease
Authors:Chapados, B.R., Hosfield, D.J., Han, S., Qiu, J., Yelent, B., Shen, B., Tainer, J.A.
Deposit date:2003-12-18
Release date:2004-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
Cell(Cambridge,Mass.), 116, 2004
1RXW
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CRYSTAL STRUCTURE OF A. FULGIDUS FEN-1 BOUND TO DNA
Descriptor:5'-d(*C*pG*pA*pT*pG*pC*pT*pA)-3', 5'-d(*T*pA*pG*pC*pA*pT*pC*pG*pG)-3', Flap structure-specific endonuclease
Authors:Chapados, B.R., Hosfield, D.J., Han, S., Qiu, J., Yelent, B., Shen, B., Tainer, J.A.
Deposit date:2003-12-18
Release date:2004-01-27
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
Cell(Cambridge,Mass.), 116, 2004
1RXZ
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C-TERMINAL REGION OF A. FULGIDUS FEN-1 COMPLEXED WITH A. FULGIDUS PCNA
Descriptor:DNA polymerase sliding clamp, Flap structure-specific endonuclease
Authors:Chapados, B.R., Hosfield, D.J., Han, S., Qiu, J., Yelent, B., Shen, B., Tainer, J.A.
Deposit date:2003-12-18
Release date:2004-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
Cell(Cambridge,Mass.), 116, 2004
4LOX
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CRYSTAL STRUCTURE OF THE I-SMAMI LAGLIDADG HOMING ENDONUCLEASE BOUND TO CLEAVED DNA
Descriptor:LAGLIDADG homing endonuclease I-SmaMI, DNA (5'-D(*CP*GP*TP*AP*CP*AP*CP*CP*TP*GP*AP*TP*AP*A)-3'), DNA (5'-D(P*TP*GP*GP*AP*GP*GP*AP*TP*AP*CP*C)-3'), ...
Authors:Chik, J., Shen, B., Stoddard, B.
Deposit date:2013-07-14
Release date:2014-09-24
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Crystal structure of a LAGLIDADG endonuclease from the Sordaria Macrospore.
To be Published
4LQ0
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CRYSTAL STRUCTURE OF THE I-LTRWI LAGLIDADG HOMING ENDONUCLEASE BOUND TO TARGET DNA.
Descriptor:LAGLIDADG homing endonuclease, top strand DNA target, bottom strand DNA target, ...
Authors:Chik, J., Shen, B., Stoddard, B.
Deposit date:2013-07-16
Release date:2014-07-16
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structural Comparisons of LAGLIDADG Homing Endonucleases.
To be Published
4OQJ
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STREPTOMCYES ALBUS JA3453 OXAZOLOMYCIN KETOSYNTHASE DOMAIN OZMQ KS1
Descriptor:PKS, POTASSIUM ION, PHOSPHATE ION, ...
Authors:Nocek, B., Mack, J., Endras, M., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2014-02-09
Release date:2014-03-19
Last modified:2016-11-02
Method:X-RAY DIFFRACTION (1.904 Å)
Cite:Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
5UMP
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CRYSTAL STRUCTURE OF TNMS3, AN ANTIBIOTIC BINDING PROTEIN FROM STREPTOMYCES SP. CB03234
Descriptor:Glyoxalase/bleomycin resisance protein/dioxygenase
Authors:Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips, G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-01-29
Release date:2018-07-04
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Resistance to Enediyne Antitumor Antibiotics by Sequestration.
Cell Chem Biol, 25, 2018
5UMQ
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CRYSTAL STRUCTURE OF TNMS1, AN ANTIBIOTIC BINDING PROTEIN FROM STREPTOMYCES SP. CB03234
Descriptor:Glyoxalase/bleomycin resisance protein/dioxygenase
Authors:Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips, G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-01-29
Release date:2018-07-04
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Resistance to Enediyne Antitumor Antibiotics by Sequestration.
Cell Chem Biol, 25, 2018
5UMW
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CRYSTAL STRUCTURE OF TNMS2, AN ANTIBIOTIC BINDING PROTEIN FROM STREPTOMYCES SP. CB03234
Descriptor:Glyoxalase/bleomycin resisance protein/dioxygenase, RIBOFLAVIN
Authors:Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips, G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-01-29
Release date:2018-07-04
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Resistance to Enediyne Antitumor Antibiotics by Sequestration.
Cell Chem Biol, 25, 2018
5UMX
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CRYSTAL STRUCTURE OF TNMS3 IN COMPLEX WITH RIBOFLAVIN
Descriptor:Glyoxalase/bleomycin resisance protein/dioxygenase, RIBOFLAVIN
Authors:Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips, G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-01-29
Release date:2018-07-04
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Resistance to Enediyne Antitumor Antibiotics by Sequestration.
Cell Chem Biol, 25, 2018
5UMY
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CRYSTAL STRUCTURE OF TNMS3 IN COMPLEX WITH TIANCIMYCIN
Descriptor:Glyoxalase/bleomycin resisance protein/dioxygenase, (1aS,11S,11aR,14Z,18R)-3,8,18-trihydroxy-11a-[(1R)-1-hydroxyethyl]-7-methoxy-11,11a-dihydro-4H-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinoline-4,9(10H)-dione
Authors:Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips, G.N., SHen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-01-29
Release date:2018-07-04
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Resistance to Enediyne Antitumor Antibiotics by Sequestration.
Cell Chem Biol, 25, 2018
5W27
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CRYSTAL STRUCTURE OF TNMS3 IN COMPLEX WITH TIANCIMYCIN (TNM B)
Descriptor:Glyoxalase/bleomycin resisance protein/dioxygenase, methyl (2E)-3-[(1aS,11S,11aS,14Z,18R)-3,18-dihydroxy-4,9-dioxo-4,9,10,11-tetrahydro-11aH-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinolin-11a-yl]but-2-enoate
Authors:Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips, G.N., SHen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-06-05
Release date:2018-06-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of TnmS3 in complex with tiancimycin (TNM B)
To Be Published
6BBX
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CRYSTAL STRUCTURE OF TNMS3 IN COMPLEX WITH TNM C
Descriptor:Glyoxalase/bleomycin resisance protein/dioxygenase, methyl (2R,3R)-2,3-dihydroxy-3-[(1aS,11S,11aR,14Z,18R)-3,7,8,18-tetrahydroxy-4,9-dioxo-4,9,10,11-tetrahydro-11aH-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinolin-11a-yl]butanoate
Authors:Chang, C.Y., Chang, C., Nocek, B., Rudolf, J.D., Joachimiak, A., Phillips, G.N., Shen, B., Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-10-19
Release date:2018-07-04
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Resistance to Enediyne Antitumor Antibiotics by Sequestration.
Cell Chem Biol, 25, 2018
1J4H
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CRYSTAL STRUCTURE ANALYSIS OF THE FKBP12 COMPLEXED WITH 000107 SMALL MOLECULE
Descriptor:FKBP12, 3-PHENYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PROPIONIC ACID ETHYL ESTER
Authors:Li, P., Ding, Y., Wang, L., Wu, B., Shu, C., Li, S., Shen, B., Rao, Z.
Deposit date:2001-09-30
Release date:2003-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design and structure-based study of new potential FKBP12 inhibitors
Biophys.J., 85, 2003
1J4I
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CRYSTAL STRUCTURE ANALYSIS OF THE FKBP12 COMPLEXED WITH 000308 SMALL MOLECULE
Descriptor:FKBP12, 4-METHYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PENTANOIC ACID
Authors:Li, P., Ding, Y., Wang, L., Wu, B., Shu, C., Li, S., Shen, B., Rao, Z.
Deposit date:2001-09-30
Release date:2003-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design and structure-based study of new potential FKBP12 inhibitors
Biophys.J., 85, 2003
4OPE
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STREPTOMCYES ALBUS JA3453 OXAZOLOMYCIN KETOSYNTHASE DOMAIN OZMH KS7
Descriptor:NRPS/PKS, NITRATE ION
Authors:Osipiuk, J., Mack, J., Endres, M., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2014-02-05
Release date:2014-02-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4OPF
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STREPTOMCYES ALBUS JA3453 OXAZOLOMYCIN KETOSYNTHASE DOMAIN OZMH KS8
Descriptor:NRPS/PKS
Authors:Osipiuk, J., Bigelow, L., Endres, M., Babnigg, G., Bingman, C.A., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2014-02-05
Release date:2014-02-19
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4QYR
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STREPTOMYCES PLATENSIS ISOMIGRASTATIN KETOSYNTHASE DOMAIN MGSE KS3
Descriptor:AT-less polyketide synthase, GLYCEROL, ACETIC ACID, ...
Authors:Kim, Y., Li, H., Endres, M., Babnigg, J., Bingman, C.A., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2014-07-25
Release date:2014-08-20
Last modified:2016-12-07
Method:X-RAY DIFFRACTION (2.902 Å)
Cite:Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4TKT
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STREPTOMYCES PLATENSIS ISOMIGRASTATIN KETOSYNTHASE DOMAIN MGSF KS6
Descriptor:AT-less polyketide synthase, CHLORIDE ION, SULFATE ION, ...
Authors:Chang, C., Li, H., Endres, M., Bingman, C., Yennamalli, R., Lohman, J.R., Ma, M., Shen, B., Phillips Jr., G.N., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2014-05-27
Release date:2014-06-11
Last modified:2016-11-02
Method:X-RAY DIFFRACTION (2.4289 Å)
Cite:Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015