6DB8
 
 | | Structural basis for promiscuous binding and activation of fluorogenic dyes by DIR2s RNA aptamer | | Descriptor: | 2-[(Z)-(3-methyl-1,3-benzoxazol-2(3H)-ylidene)methyl]-3-(3-sulfopropyl)-1,3-benzothiazol-3-ium, Fab-Heavy chain, Fab-Light chain, ... | | Authors: | Shao, Y, Shelke, S.A, Laski, A, Piccirilli, J.A. | | Deposit date: | 2018-05-02 | | Release date: | 2018-11-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.86541343 Å) | | Cite: | Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif.
Nat Commun, 9, 2018
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6DB9
 | | Structural basis for promiscuous binding and activation of fluorogenic dyes by DIR2s RNA aptamer | | Descriptor: | Fab-Heavy-Chain, Fab-Light-Chain, MAGNESIUM ION, ... | | Authors: | Shao, Y, Shelke, S.A, Laski, A, Piccirilli, J.A. | | Deposit date: | 2018-05-02 | | Release date: | 2018-11-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.025 Å) | | Cite: | Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif.
Nat Commun, 9, 2018
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5C7W
 | | 5'-monophosphate Z:P Guanine Riboswitch bound to hypoxanthine. | | Descriptor: | 5'-monophosphate Z:P guanine riboswitch, COBALT HEXAMMINE(III), HYPOXANTHINE | | Authors: | Hernandez, A.R, Shao, Y, Hoshika, S, Yang, Z, Shelke, S.A, Herrou, J, Kim, H.-J, Kim, M.-J, Piccirilli, J.A, Benner, S.A. | | Deposit date: | 2015-06-25 | | Release date: | 2015-08-12 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.22 Å) | | Cite: | A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair.
Angew.Chem.Int.Ed.Engl., 54, 2015
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5C7U
 | | 5'-monophosphate wt Guanine Riboswitch bound to hypoxanthine. | | Descriptor: | 5'-monophosphate wt guanine riboswitch, COBALT HEXAMMINE(III), HYPOXANTHINE | | Authors: | Hernandez, A.R, Shao, Y, Hoshika, S, Yang, Z, Shelke, S.A, Herrou, J, Kim, H.-J, Kim, M.-J, Piccirilli, J.A, Benner, S.A. | | Deposit date: | 2015-06-24 | | Release date: | 2015-08-12 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair.
Angew.Chem.Int.Ed.Engl., 54, 2015
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4Q9Q
 | | Crystal structure of an RNA aptamer bound to bromo-ligand analog in complex with Fab | | Descriptor: | (5Z)-5-(3-bromobenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ... | | Authors: | Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | | Deposit date: | 2014-05-01 | | Release date: | 2014-06-18 | | Last modified: | 2017-07-26 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
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4Q9R
 | | Crystal structure of an RNA aptamer bound to trifluoroethyl-ligand analog in complex with Fab | | Descriptor: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ... | | Authors: | Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | | Deposit date: | 2014-05-01 | | Release date: | 2014-06-18 | | Last modified: | 2017-07-26 | | Method: | X-RAY DIFFRACTION (3.12 Å) | | Cite: | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
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6B14
 | | Crystal structure of Spinach RNA aptamer in complex with Fab BL3-6S97N | | Descriptor: | Heavy chain of Fab BL3-6S97N, Light chain of Fab BL3-6S97N, MAGNESIUM ION, ... | | Authors: | DasGupta, S, Shelke, S.A, Piccirilli, J.A. | | Deposit date: | 2017-09-16 | | Release date: | 2017-12-27 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Affinity maturation of a portable Fab-RNA module for chaperone-assisted RNA crystallography.
Nucleic Acids Res., 46, 2018
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6B3K
 | | Crystal structure of mutant Spinach RNA aptamer in complex with Fab BL3-6 | | Descriptor: | Heavy chain of Fab BL3-6, Light chain of Fab BL3-6, MAGNESIUM ION, ... | | Authors: | DasGupta, S, Koirala, D, Shelke, S.A, Piccirilli, J.A. | | Deposit date: | 2017-09-22 | | Release date: | 2017-12-27 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Affinity maturation of a portable Fab-RNA module for chaperone-assisted RNA crystallography.
Nucleic Acids Res., 46, 2018
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6MWN
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3OT0
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6XJQ
 | | Crystal structure of a self-alkylating ribozyme - alkylated form with biotinylated epoxide substrate | | Descriptor: | 2-{[(4R)-4-hydroxyhexyl]oxy}ethyl 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate, Fab HAVx Heavy Chain, Fab HAVx Light Chain, ... | | Authors: | Koirala, D, Piccirilli, J.A. | | Deposit date: | 2020-06-24 | | Release date: | 2022-01-19 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.708 Å) | | Cite: | Structural basis for substrate binding and catalysis by a self-alkylating ribozyme.
Nat.Chem.Biol., 18, 2022
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6XJY
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6XJW
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6XJZ
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4KZD
 | | Crystal structure of an RNA aptamer in complex with fluorophore and Fab | | Descriptor: | 4-(3,5-difluoro-4-hydroxybenzyl)-1,2-dimethyl-1H-imidazol-5-ol, BL3-6 Fab antibody, heavy chain, ... | | Authors: | Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | | Deposit date: | 2013-05-29 | | Release date: | 2014-06-18 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.186 Å) | | Cite: | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
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4KZE
 | | Crystal structure of an RNA aptamer in complex with Fab | | Descriptor: | BL3-6 Fab antibody, heavy chain, light chain, ... | | Authors: | Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | | Deposit date: | 2013-05-29 | | Release date: | 2014-06-18 | | Last modified: | 2014-07-30 | | Method: | X-RAY DIFFRACTION (2.404 Å) | | Cite: | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
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