6DNY
 
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2MOV
 | | Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal Derived AGEs. | | Descriptor: | Advanced glycosylation end product-specific receptor, N~5~-[(5R)-5-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl]-L-ornithine | | Authors: | Shekhtman, A, Xue, J, Ray, R, Singer, D, Bohme, D, Burz, D.S, Rai, V, Hoffman, R. | | Deposit date: | 2014-05-05 | | Release date: | 2014-06-25 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs.
Biochemistry, 53, 2014
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8FG1
 | | Human diaphanous inhibitory domain bound to diaphanous autoregulatory domain | | Descriptor: | Protein diaphanous homolog 1 | | Authors: | Ramirez, L.M.S, Theophall, G, Premo, A, Manigrasso, M, Yepuri, G, Burz, D, Ramasamy, R, Schmidt, A.M, Shekhtman, A. | | Deposit date: | 2022-12-12 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-15 | | Method: | SOLUTION NMR | | Cite: | Disruption of the productive encounter complex results in dysregulation of DIAPH1 activity.
J.Biol.Chem., 299, 2023
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6VXG
 | | Structure of the C-terminal Domain of RAGE and Its Inhibitor | | Descriptor: | Advanced glycosylation end product-specific receptor, N-(4-{7-cyano-4-[(morpholin-4-yl)methyl]quinolin-2-yl}phenyl)acetamide | | Authors: | Ramirez, L, Shekhtman, A. | | Deposit date: | 2020-02-21 | | Release date: | 2021-02-24 | | Last modified: | 2022-03-09 | | Method: | SOLUTION NMR | | Cite: | Small-molecule antagonism of the interaction of the RAGE cytoplasmic domain with DIAPH1 reduces diabetic complications in mice.
Sci Transl Med, 13, 2021
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7MLA
 | | Solution NMR structure of HDMX in complex with Zn and MCo-52-2 | | Descriptor: | MCo-52-2, Protein Mdm4, ZINC ION | | Authors: | Ramirez, L.S, Theophall, G, Chaudhuri, D, Camarero, J.C, Shekhtman, A. | | Deposit date: | 2021-04-28 | | Release date: | 2022-05-04 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of HDMX in complex with Zn and cyclotide 52-2
To Be Published
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1JEG
 | | Solution structure of the SH3 domain from C-terminal Src Kinase complexed with a peptide from the tyrosine phosphatase PEP | | Descriptor: | HEMATOPOIETIC CELL PROTEIN-TYROSINE PHOSPHATASE 70Z-PEP, TYROSINE-PROTEIN KINASE CSK | | Authors: | Ghose, R, Shekhtman, A, Goger, M.J, Ji, H, Cowburn, D. | | Deposit date: | 2001-06-17 | | Release date: | 2001-10-31 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | A novel, specific interaction involving the Csk SH3 domain and its natural ligand.
Nat.Struct.Biol., 8, 2001
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6DST
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2L7U
 | | Structure of CEL-PEP-RAGE V domain complex | | Descriptor: | Advanced glycosylation end product-specific receptor, Serum albumin peptide | | Authors: | Xue, J, Rai, V, Schmidt, A, Frolov, S, Reverdatto, S, Singer, D, Chabierski, S, Xie, J, Burz, D, Shekhtman, A, Hoffman, R. | | Deposit date: | 2010-12-23 | | Release date: | 2011-05-18 | | Last modified: | 2023-11-29 | | Method: | SOLUTION NMR | | Cite: | Advanced glycation end product recognition by the receptor for AGEs.
Structure, 19, 2011
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2K6X
 | | Autoregulation of a Group 1 Bacterial Sigma Factor Involves the Formation of a Region 1.1- Induced Compacted Structure | | Descriptor: | RNA polymerase sigma factor rpoD | | Authors: | Schwartz, E.C, Shekhtman, A, Dutta, K, Pratt, M.R, Cowburn, D, Darst, S, Muir, T.W. | | Deposit date: | 2008-07-28 | | Release date: | 2008-10-28 | | Last modified: | 2021-10-20 | | Method: | SOLUTION NMR | | Cite: | Autoregulation of a Group 1 Bacterial Sigma Factor Involves the Formation of a Region 1.1 - Induced Compacted Structure
Chem.Biol., 15, 2008
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2LMB
 | | Solution Structure of C-terminal RAGE (ctRAGE) | | Descriptor: | Advanced glycosylation end product-specific receptor | | Authors: | Rai, V, Maldonado, A.Y, Burz, D.S, Reverdatto, S, Schmidt, A, Shekhtman, A. | | Deposit date: | 2011-11-29 | | Release date: | 2011-12-21 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Signal transduction in receptor for advanced glycation end products (RAGE): solution structure of C-terminal rage (ctRAGE) and its binding to mDia1.
J.Biol.Chem., 287, 2012
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5I0A
 | | RecA mini intein in complex with cisplatin | | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, Cisplatin, Intein, ... | | Authors: | Li, Z, Zhang, J, Li, H.M. | | Deposit date: | 2016-02-03 | | Release date: | 2016-09-21 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural insights into protein splicing inhibition by platinum therapeutics as potential anti-microbials
To be published
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5K08
 | | RecA mini intein-Zeise's salt complex | | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, RecA mini intein, SULFATE ION, ... | | Authors: | Li, Z, Li, H.M. | | Deposit date: | 2016-05-17 | | Release date: | 2016-09-21 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.401 Å) | | Cite: | Structural insights into protein splicing inhibition by platinum therapeutics as potential anti-microbials
To be published
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2M86
 | | Solution structure of Hdm2 with engineered cyclotide | | Descriptor: | E3 ubiquitin-protein ligase Mdm2, MCo-PMI | | Authors: | Majumder, S, Ji, Y, Millard, M, Borra, R, Bi, T, Elnagar, A.Y, Neamati, N, Camarero, J.A. | | Deposit date: | 2013-05-07 | | Release date: | 2013-07-31 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide.
J.Am.Chem.Soc., 135, 2013
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